Compounds > sorafenib
Page last updated: 2024-09-05

sorafenib and benztropine

sorafenib has been researched along with benztropine in 2 studies

Compound Research Comparison

Studies
(sorafenib)		Trials
(sorafenib)		Recent Studies (post-2010)
(sorafenib)		Studies
(benztropine)		Trials
(benztropine)		Recent Studies (post-2010) (benztropine)
6,5207305,2517359385

Protein Interaction Comparison

ProteinTaxonomysorafenib (IC50)benztropine (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.061
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)1.391
Muscarinic acetylcholine receptor M2Homo sapiens (human)0.0366
Muscarinic acetylcholine receptor M4Homo sapiens (human)0.0037
Muscarinic acetylcholine receptor M5Homo sapiens (human)0.002
Alpha-2A adrenergic receptorHomo sapiens (human)0.544
Muscarinic acetylcholine receptor M1Homo sapiens (human)0.0005
Alpha-2B adrenergic receptorHomo sapiens (human)0.065
Alpha-2C adrenergic receptorHomo sapiens (human)0.395
Muscarinic acetylcholine receptor M3Homo sapiens (human)0.0106
Sodium-dependent noradrenaline transporter Homo sapiens (human)1.391
Histamine H2 receptorHomo sapiens (human)1.206
Alpha-1D adrenergic receptorHomo sapiens (human)0.052
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.024
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.061
Histamine H1 receptorHomo sapiens (human)0.0032
D(3) dopamine receptorHomo sapiens (human)0.654
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.2
5-hydroxytryptamine receptor 6Homo sapiens (human)2.788
Sodium-dependent dopamine transporter Homo sapiens (human)0.2948
Sigma non-opioid intracellular receptor 1Homo sapiens (human)0.139

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1

Reviews

1 review(s) available for sorafenib and benztropine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

1 other study(ies) available for sorafenib and benztropine

ArticleYear
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012