Page last updated: 2024-09-05

sorafenib and benzimidazole

sorafenib has been researched along with benzimidazole in 3 studies

Compound Research Comparison

Studies (sorafenib)	Trials (sorafenib)	Recent Studies (post-2010) (sorafenib)	Studies (benzimidazole)	Trials (benzimidazole)	Recent Studies (post-2010) (benzimidazole)
6,520	730	5,251	1,186	16	702

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	2 (66.67)	24.3611
2020's	1 (33.33)	2.80

Authors

Authors	Studies
Korzeniecki, C; Priefer, R	1
Elmorsy, MA; Gomaa, RM; Mostafa, AS	1
Chuang, YT; Hsu, MH; Liao, YJ; Liu, CL; Suk, FM; Wang, JP	1

Reviews

1 review(s) available for sorafenib and benzimidazole

Article	Year
Targeting KRAS mutant cancers by preventing signaling transduction in the MAPK pathway. European journal of medicinal chemistry, 2021, Feb-05, Volume: 211 Topics: Humans; Models, Molecular; Molecular Structure; Mutation; Protein Kinase Inhibitors; Proto-Oncogene Proteins p21(ras); Signal Transduction	2021

Other Studies

2 other study(ies) available for sorafenib and benzimidazole

Article	Year
Design and synthesis of 2-phenyl benzimidazole derivatives as VEGFR-2 inhibitors with anti-breast cancer activity. Chemical biology & drug design, 2019, Volume: 93, Issue:4 Topics: Benzimidazoles; Binding Sites; Breast Neoplasms; Cell Line; Cell Survival; Doxorubicin; Drug Design; Female; Humans; Inhibitory Concentration 50; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Sorafenib; Structure-Activity Relationship; Vascular Endothelial Growth Factor Receptor-2	2019
Treatment with a new benzimidazole derivative bearing a pyrrolidine side chain overcomes sorafenib resistance in hepatocellular carcinoma. Scientific reports, 2019, 11-21, Volume: 9, Issue:1 Topics: Animals; Benzimidazoles; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Mice; Mice, Inbred NOD; Pyrrolidines; Sorafenib; Xenograft Model Antitumor Assays	2019

Article

Year

Design and synthesis of 2-phenyl benzimidazole derivatives as VEGFR-2 inhibitors with anti-breast cancer activity.

Chemical biology & drug design, 2019, Volume: 93, Issue:4

Topics: Benzimidazoles; Binding Sites; Breast Neoplasms; Cell Line; Cell Survival; Doxorubicin; Drug Design; Female; Humans; Inhibitory Concentration 50; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Sorafenib; Structure-Activity Relationship; Vascular Endothelial Growth Factor Receptor-2

2019

Treatment with a new benzimidazole derivative bearing a pyrrolidine side chain overcomes sorafenib resistance in hepatocellular carcinoma.

Scientific reports, 2019, 11-21, Volume: 9, Issue:1

Topics: Animals; Benzimidazoles; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Mice; Mice, Inbred NOD; Pyrrolidines; Sorafenib; Xenograft Model Antitumor Assays

2019