Compounds > sorafenib
Page last updated: 2024-09-05

sorafenib and at 9283

sorafenib has been researched along with at 9283 in 3 studies

Compound Research Comparison

Studies
(sorafenib)		Trials
(sorafenib)		Recent Studies (post-2010)
(sorafenib)		Studies
(at 9283)		Trials
(at 9283)		Recent Studies (post-2010) (at 9283)
6,5207305,25123020

Protein Interaction Comparison

ProteinTaxonomysorafenib (IC50)at 9283 (IC50)
Aurora kinase AHomo sapiens (human)0.4331
Tyrosine-protein kinase JAK2Homo sapiens (human)0.0014
Ribosomal protein S6 kinase alpha-4Homo sapiens (human)0.01
Tyrosine-protein kinase ABL1Homo sapiens (human)0.0055
Cyclin-dependent kinase 1Homo sapiens (human)1.7
Tyrosine-protein kinase YesHomo sapiens (human)0.001
Proto-oncogene tyrosine-protein kinase receptor RetHomo sapiens (human)0.001
Fibroblast growth factor receptor 1Homo sapiens (human)0.01
Proto-oncogene tyrosine-protein kinase SrcHomo sapiens (human)0.01
G2/mitotic-specific cyclin-B1Homo sapiens (human)1.7
Platelet-derived growth factor receptor alphaHomo sapiens (human)0.01
Vascular endothelial growth factor receptor 1 Homo sapiens (human)0.01
Fibroblast growth factor receptor 2Homo sapiens (human)0.0055
Fibroblast growth factor receptor 3Homo sapiens (human)0.01
Non-receptor tyrosine-protein kinase TYK2Homo sapiens (human)0.001
Vascular endothelial growth factor receptor 3Homo sapiens (human)0.001
Vascular endothelial growth factor receptor 2Homo sapiens (human)0.01
Receptor-type tyrosine-protein kinase FLT3Homo sapiens (human)0.01
Glycogen synthase kinase-3 betaHomo sapiens (human)0.001
Ribosomal protein S6 kinase alpha-3Homo sapiens (human)0.001
Tyrosine-protein kinase JAK3Homo sapiens (human)0.0011
Tyrosine-protein kinase MerHomo sapiens (human)0.001
Maternal embryonic leucine zipper kinaseHomo sapiens (human)0.685
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrialHomo sapiens (human)0.01
Serine/threonine-protein kinase D1Homo sapiens (human)0.01
Ribosomal protein S6 kinase alpha-2Homo sapiens (human)0.001
Cyclin-dependent kinase-like 3Homo sapiens (human)1.1
Dual specificity tyrosine-phosphorylation-regulated kinase 2Homo sapiens (human)0.57
Aurora kinase BHomo sapiens (human)0.3046
Serine/threonine-protein kinase 17AHomo sapiens (human)0.01

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (33.33)24.3611
2020's2 (66.67)2.80

Authors

AuthorsStudies
Aiche, S; Bassermann, F; Becker, W; Canevari, G; Casale, E; Depaolini, SR; Ehrlich, HC; Felder, ER; Feuchtinger, A; Garz, AK; Gohlke, BO; Götze, K; Greif, PA; Hahne, H; Heinzlmeir, S; Helm, D; Huenges, J; Jeremias, I; Kayser, G; Klaeger, S; Koch, H; Koenig, PA; Kramer, K; Kuster, B; Médard, G; Meng, C; Petzoldt, S; Polzer, H; Preissner, R; Qiao, H; Reinecke, M; Reiter, K; Rueckert, L; Ruland, J; Ruprecht, B; Schlegl, J; Schmidt, T; Schneider, S; Schoof, M; Spiekermann, K; Tõnisson, N; Vick, B; Vooder, T; Walch, A; Wilhelm, M; Wu, Z; Zecha, J; Zolg, DP1
Bharate, SB; Raghuvanshi, R1
Berger, BT; Chaikuad, A; Drápela, S; Knapp, S; Maier, L; Němec, V; Paruch, K; Souček, K1

Other Studies

3 other study(ies) available for sorafenib and at 9283

ArticleYear
The target landscape of clinical kinase drugs.
    Science (New York, N.Y.), 2017, 12-01, Volume: 358, Issue:6367

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cytokines; Drug Discovery; fms-Like Tyrosine Kinase 3; Humans; Leukemia, Myeloid, Acute; Lung Neoplasms; Mice; Molecular Targeted Therapy; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Proteomics; Xenograft Model Antitumor Assays

2017
Recent Developments in the Use of Kinase Inhibitors for Management of Viral Infections.
    Journal of medicinal chemistry, 2022, 01-27, Volume: 65, Issue:2

    Topics: Antiviral Agents; COVID-19; COVID-19 Drug Treatment; Drug Approval; Drug Repositioning; High-Throughput Screening Assays; Humans; Protein Kinase Inhibitors; SARS-CoV-2; United States; United States Food and Drug Administration; Virus Diseases

2022
Highly selective inhibitors of protein kinases CLK and HIPK with the furo[3,2-b]pyridine core.
    European journal of medicinal chemistry, 2021, Apr-05, Volume: 215

    Topics: Animals; Carrier Proteins; Crystallography, X-Ray; Furans; Humans; MCF-7 Cells; Mice; Molecular Structure; Protein Binding; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Pyridines; Structure-Activity Relationship

2021