Compounds > sorafenib
Page last updated: 2024-09-05

sorafenib and ascorbic acid

sorafenib has been researched along with ascorbic acid in 5 studies

Compound Research Comparison

Studies
(sorafenib)		Trials
(sorafenib)		Recent Studies (post-2010)
(sorafenib)		Studies
(ascorbic acid)		Trials
(ascorbic acid)		Recent Studies (post-2010) (ascorbic acid)
6,5207305,25145,2612,49711,176

Protein Interaction Comparison

ProteinTaxonomysorafenib (IC50)ascorbic acid (IC50)
Chain A, Hyaluronidase, phage associatedStreptococcus pyogenes1000
UreaseCanavalia ensiformis (jack bean)8.59
Solute carrier family 23 member 1Homo sapiens (human)156

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Kim, JK; Seo, MS; Shim, JY1
Antony, AN; Bisetto, S; Doria, C; Hoek, JB; Levine, M; Monti, DA; Newberg, A; Rouleau, L1
Abel, T; Haralampiev, I; Herrmann, A; Huster, D; Luckner, M; Müller, P; Scheidt, HA1
Bito, T; Hirai, M; Hirano, T; Ishida, T; Kaku, K; Kume, M; Makimoto, H; Nakagawa, T; Nishigori, C; Nishioka, T; Shichiri, H; Yamamoto, K; Yano, I1

Reviews

1 review(s) available for sorafenib and ascorbic acid

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

4 other study(ies) available for sorafenib and ascorbic acid

ArticleYear
High-Dose Vitamin C Promotes Regression of Multiple Pulmonary Metastases Originating from Hepatocellular Carcinoma.
    Yonsei medical journal, 2015, Volume: 56, Issue:5

    Topics: Aged; Antineoplastic Agents; Ascorbic Acid; Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; Combined Modality Therapy; Female; Humans; Liver Neoplasms; Lung Neoplasms; Neoplasm Recurrence, Local; Niacinamide; Phenylurea Compounds; Sorafenib; Treatment Outcome

2015
Synergistic effects of ascorbate and sorafenib in hepatocellular carcinoma: New insights into ascorbate cytotoxicity.
    Free radical biology & medicine, 2016, Volume: 95

    Topics: Apoptosis; Ascorbic Acid; Carcinoma, Hepatocellular; Cell Proliferation; Drug Synergism; Hep G2 Cells; Humans; Hydrogen Peroxide; Liver Neoplasms; Mitochondria; Niacinamide; Phenylurea Compounds; Sorafenib

2016
The interaction of sorafenib and regorafenib with membranes is modulated by their lipid composition.
    Biochimica et biophysica acta, 2016, Volume: 1858, Issue:11

    Topics: Antineoplastic Agents; Ascorbic Acid; Cell Membrane; Cell Membrane Permeability; Cholesterol; Dithionite; Kinetics; Niacinamide; Oxidation-Reduction; Phenylurea Compounds; Phosphatidylcholines; Phosphatidylethanolamines; Pyridines; Sorafenib; Spin Labels; Staining and Labeling; Unilamellar Liposomes

2016
Effects of Ascorbyl-2-phosphate Magnesium on Human Keratinocyte Toxicity and Pathological Changes by Sorafenib.
    Biological & pharmaceutical bulletin, 2017, Volume: 40, Issue:9

    Topics: Antineoplastic Agents; Apoptosis; Ascorbic Acid; Cell Line; Hand-Foot Syndrome; Humans; Keratinocytes; Magnesium; Niacinamide; Phenylurea Compounds; Phosphorylation; Reactive Oxygen Species; RNA, Small Interfering; Signal Transduction; Skin; Sorafenib; STAT3 Transcription Factor

2017