Compounds > sorafenib
Page last updated: 2024-09-05

sorafenib and apigenin

sorafenib has been researched along with apigenin in 3 studies

Compound Research Comparison

Studies
(sorafenib)		Trials
(sorafenib)		Recent Studies (post-2010)
(sorafenib)		Studies
(apigenin)		Trials
(apigenin)		Recent Studies (post-2010) (apigenin)
6,5207305,2513,273752,086

Protein Interaction Comparison

ProteinTaxonomysorafenib (IC50)apigenin (IC50)
Chain A, Casein kinase II subunit alphaZea mays1.2
Chain A, Casein kinase II subunit alphaZea mays1.2
Chain A, Casein Kinase Ii Subunit AlphaZea mays1.2
Aldo-keto reductase family 1 member B10Homo sapiens (human)6.6
G2/mitotic-specific cyclin-B2Homo sapiens (human)4
Poly [ADP-ribose] polymerase tankyrase-1Homo sapiens (human)3.1311
Estrogen receptorHomo sapiens (human)1.253
Cytochrome P450 1A1Homo sapiens (human)0.427
MyeloperoxidaseHomo sapiens (human)3.8
Cytochrome P450 1A2Homo sapiens (human)0.795
Cyclin-dependent kinase 1Homo sapiens (human)4
Beta-glucuronidaseRattus norvegicus (Norway rat)2.8
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)6.67
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 23.02
Androgen receptorHomo sapiens (human)5.2
Serine/threonine-protein kinase pim-1Homo sapiens (human)0.94
AromataseHomo sapiens (human)3.275
17-beta-hydroxysteroid dehydrogenase type 1Homo sapiens (human)0.71
Pyruvate kinase PKMHomo sapiens (human)0.99
G2/mitotic-specific cyclin-B1Homo sapiens (human)4
G2/mitotic-specific cyclin-BMarthasterias glacialis (spiny starfish)2.175
Glycogen synthase kinase-3 betaRattus norvegicus (Norway rat)2.175
Casein kinase II subunit alpha'Homo sapiens (human)0.85
Amine oxidase [flavin-containing] AHomo sapiens (human)1.398
Amine oxidase [flavin-containing] BHomo sapiens (human)1.12
Dipeptidyl peptidase 4Homo sapiens (human)0.14
Proteasome subunit beta type-5Homo sapiens (human)1.4
Prostaglandin G/H synthase 2Homo sapiens (human)8
Receptor-type tyrosine-protein kinase FLT3Homo sapiens (human)1.45
Tyrosine-protein kinase SYKHomo sapiens (human)4.2
Xanthine dehydrogenase/oxidaseHomo sapiens (human)1.95
Glycogen synthase kinase-3 alphaHomo sapiens (human)1.4
Glycogen synthase kinase-3 betaHomo sapiens (human)1.4
Mitogen-activated protein kinase 10Homo sapiens (human)2.2
Casein kinase II subunit betaHomo sapiens (human)0.85
Casein kinase II subunit alphaHomo sapiens (human)0.84
Xanthine dehydrogenase/oxidaseBos taurus (cattle)3.57
MO15-related protein kinase Pfmrk Plasmodium falciparum (malaria parasite P. falciparum)7
Cyclin-dependent kinase 6Homo sapiens (human)2.08
Cyclin-dependent-like kinase 5 Homo sapiens (human)2.06
Cyclin homologHerpesvirus saimiri (strain 11)2.175
Cyclin-dependent kinase 5 activator 1Homo sapiens (human)2.06
Mitogen-activated protein kinase 14Homo sapiens (human)2.2
Cytochrome P450 1B1Homo sapiens (human)0.1925
Integrase Human immunodeficiency virus 11.5
Casein kinase II subunit alpha 3Homo sapiens (human)0.8
G2/mitotic-specific cyclin-B3Homo sapiens (human)4
Estrogen receptor betaHomo sapiens (human)0.13
Aurora kinase BHomo sapiens (human)3.96
NACHT, LRR and PYD domains-containing protein 3 Homo sapiens (human)10
Cyclin-dependent kinase 1Oryzias latipes (Japanese medaka)2.175
Poly [ADP-ribose] polymerase tankyrase-2Homo sapiens (human)2.9256
MAP kinase-interacting serine/threonine-protein kinase 2Homo sapiens (human)0.308
NADPH oxidase 4Homo sapiens (human)1.13
Inositol hexakisphosphate kinase 2Homo sapiens (human)7.1
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)4.5

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's3 (100.00)2.80

Authors

AuthorsStudies
Delabio, LC; Dutra, JP; Hembecker, M; Kita, DH; Moure, VR; Pereira, GDS; Scheiffer, G; Valdameri, G; Zattoni, IF1
Dodurga, Y; Elmas, L; Seçme, M; Şirin, N1
Akhtar, K; Arjmand, F; Khan, MA; Siddique, HR; Singh, D1

Reviews

1 review(s) available for sorafenib and apigenin

ArticleYear
Targeting breast cancer resistance protein (BCRP/ABCG2): Functional inhibitors and expression modulators.
    European journal of medicinal chemistry, 2022, Jul-05, Volume: 237

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; Breast Neoplasms; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Neoplasm Proteins; Neoplastic Stem Cells

2022

Other Studies

2 other study(ies) available for sorafenib and apigenin

ArticleYear
Investigation of possible effects of apigenin, sorafenib and combined applications on apoptosis and cell cycle in hepatocellular cancer cells.
    Gene, 2020, May-05, Volume: 737

    Topics: Apigenin; Apoptosis; Cell Cycle; Drug Synergism; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Sorafenib

2020
Apigenin alleviates cancer drug Sorafenib induced multiple toxic effects in Swiss albino mice via anti-oxidative stress.
    Toxicology and applied pharmacology, 2022, 07-15, Volume: 447

    Topics: Animals; Antineoplastic Agents; Antioxidants; Apigenin; Apoptosis; Humans; Mice; Neoplasms; Oxidative Stress; Sorafenib

2022