sorafenib has been researched along with amg 925 in 1 studies
| Studies (sorafenib) | Trials (sorafenib) | Recent Studies (post-2010) (sorafenib) | Studies (amg 925) | Trials (amg 925) | Recent Studies (post-2010) (amg 925) |
|---|---|---|---|---|---|
| 6,520 | 730 | 5,251 | 10 | 0 | 10 |
| Protein | Taxonomy | sorafenib (IC50) | amg 925 (IC50) |
|---|---|---|---|
| Cyclin-dependent kinase 1 | Homo sapiens (human) | 2.22 | |
| Cyclin-dependent kinase 4 | Homo sapiens (human) | 0.0097 | |
| G2/mitotic-specific cyclin-B1 | Homo sapiens (human) | 2.22 | |
| G1/S-specific cyclin-D1 | Homo sapiens (human) | 0.003 | |
| Cyclin-dependent kinase 2 | Homo sapiens (human) | 0.375 | |
| Receptor-type tyrosine-protein kinase FLT3 | Homo sapiens (human) | 0.002 | |
| Cyclin-dependent kinase 6 | Homo sapiens (human) | 0.008 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Alba, GQ; Ayres, M; Carlson, TJ; Chen, A; Chen, X; Cho, R; Connors, RV; Dai, K; DeGraffenreid, M; Deignan, JT; Duquette, J; Eksterowicz, J; Fan, P; Fisher, B; Fu, J; Gribble, MW; Huard, JN; Kaizerman, J; Kamb, A; Keegan, KS; Li, C; Li, K; Li, Y; Li, Z; Liang, L; Liu, W; Lively, SE; Lo, MC; Ma, J; McGee, LR; McMinn, DL; Medina, JC; Mihalic, JT; Modi, K; Ngo, R; Pattabiraman, K; Piper, DE; Queva, C; Ragains, ML; Suchomel, J; Thibault, S; Walker, N; Wang, X; Wang, Z; Wanska, M; Wehn, PM; Weidner, MF; Wickramasinghe, D; Zhang, AJ; Zhao, X | 1 |
1 other study(ies) available for sorafenib and amg 925
| Article | Year |
|---|---|
Discovery of AMG 925, a FLT3 and CDK4 dual kinase inhibitor with preferential affinity for the activated state of FLT3.
Topics: Animals; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase 6; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dogs; Drug Discovery; fms-Like Tyrosine Kinase 3; Heterocyclic Compounds, 3-Ring; Humans; Macaca fascicularis; Naphthyridines; Protein Kinase Inhibitors; Rats; Structure-Activity Relationship; U937 Cells | 2014 |