Compounds > sorafenib
Page last updated: 2024-09-05

sorafenib and amg 458

sorafenib has been researched along with amg 458 in 1 studies

Compound Research Comparison

Studies
(sorafenib)		Trials
(sorafenib)		Recent Studies (post-2010)
(sorafenib)		Studies
(amg 458)		Trials
(amg 458)		Recent Studies (post-2010) (amg 458)
6,5207305,25115012

Protein Interaction Comparison

ProteinTaxonomysorafenib (IC50)amg 458 (IC50)
Aurora kinase AHomo sapiens (human)1
Tyrosine-protein kinase ABL1Homo sapiens (human)1
Insulin receptorHomo sapiens (human)1
Tyrosine-protein kinase LckHomo sapiens (human)0.865
Tyrosine-protein kinase Fes/FpsHomo sapiens (human)0.706
Macrophage colony-stimulating factor 1 receptorHomo sapiens (human)0.238
Tyrosine-protein kinase LynHomo sapiens (human)0.506
Insulin-like growth factor 1 receptorHomo sapiens (human)1
Hepatocyte growth factor receptorHomo sapiens (human)0.0434
Tyrosine-protein kinase FgrHomo sapiens (human)0.328
Mast/stem cell growth factor receptor KitHomo sapiens (human)10
Proto-oncogene tyrosine-protein kinase SrcHomo sapiens (human)1
Hepatocyte growth factor receptorMus musculus (house mouse)0.12
RAC-alpha serine/threonine-protein kinaseHomo sapiens (human)10
Vascular endothelial growth factor receptor 2Homo sapiens (human)0.845
Receptor-type tyrosine-protein kinase FLT3Homo sapiens (human)0.391
Tyrosine-protein kinase CSKHomo sapiens (human)0.165
Tyrosine-protein kinase BlkHomo sapiens (human)0.519
Cytoplasmic tyrosine-protein kinase BMXHomo sapiens (human)0.363
Tyrosine-protein kinase JAK3Homo sapiens (human)1
Angiopoietin-1 receptorHomo sapiens (human)1
Macrophage-stimulating protein receptorHomo sapiens (human)0.01
Tyrosine-protein kinase BTKHomo sapiens (human)1
Tyrosine-protein kinase ITK/TSKHomo sapiens (human)0.062
Aurora kinase BHomo sapiens (human)1

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Guo, M; He, J; Jiang, X; Jiang, Y; Li, J; Liu, J; Ouyang, L; Wang, J; Zhang, J; Zhang, S1

Reviews

1 review(s) available for sorafenib and amg 458

ArticleYear
Recent advances in the development of dual VEGFR and c-Met small molecule inhibitors as anticancer drugs.
    European journal of medicinal chemistry, 2016, Jan-27, Volume: 108

    Topics: Antineoplastic Agents; Drug Discovery; Humans; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-met; Pyridines; Quinazolines; Quinolones; Receptors, Vascular Endothelial Growth Factor; Small Molecule Libraries

2016