Page last updated: 2024-09-05

sorafenib and alsterpaullone

sorafenib has been researched along with alsterpaullone in 5 studies

Compound Research Comparison

Studies
(sorafenib)
Trials
(sorafenib)
Recent Studies (post-2010)
(sorafenib)
Studies
(alsterpaullone)
Trials
(alsterpaullone)
Recent Studies (post-2010) (alsterpaullone)
6,5207305,25180031

Protein Interaction Comparison

ProteinTaxonomysorafenib (IC50)alsterpaullone (IC50)
Chain A, Glycogen Synthase Kinase-3 BetaHomo sapiens (human)0.004
Chain B, Glycogen Synthase Kinase-3 BetaHomo sapiens (human)0.004
Chain A, Glycogen Synthase Kinase-3 BetaHomo sapiens (human)0.004
G2/mitotic-specific cyclin-B2Homo sapiens (human)0.035
Cyclin-dependent kinase 1Homo sapiens (human)0.0321
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 21.5
G2/mitotic-specific cyclin-B1Homo sapiens (human)0.035
G2/mitotic-specific cyclin-BMarthasterias glacialis (spiny starfish)0.0263
Glycogen synthase kinase-3 betaRattus norvegicus (Norway rat)0.0263
Cyclin-A2Homo sapiens (human)0.015
Cyclin-dependent kinase 2Homo sapiens (human)0.015
Glycogen synthase kinase-3 alphaHomo sapiens (human)0.0043
Glycogen synthase kinase-3 betaHomo sapiens (human)0.0105
Cyclin-dependent-like kinase 5 Homo sapiens (human)0.0608
Cyclin-dependent kinase 5 activator 1Homo sapiens (human)0.0815
G2/mitotic-specific cyclin-B3Homo sapiens (human)0.035
Cyclin-dependent kinase 1Oryzias latipes (Japanese medaka)0.0263

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's1 (20.00)24.3611
2020's3 (60.00)2.80

Authors

AuthorsStudies
Alessi, DR; Arthur, JS; Bain, J; Cohen, P; Elliott, M; Hastie, CJ; Klevernic, I; McLauchlan, H; Plater, L; Shpiro, N1
Hajduk, PJ; Johnson, EF; Kifle, L; Merta, PJ; Metz, JT; Soni, NB1
Bharate, SB; Raghuvanshi, R1
Caballero, E; García-Cárceles, J; Gil, C; Martínez, A1
Laufer, S; Pillaiyar, T1

Reviews

2 review(s) available for sorafenib and alsterpaullone

ArticleYear
Kinase Inhibitors as Underexplored Antiviral Agents.
    Journal of medicinal chemistry, 2022, 01-27, Volume: 65, Issue:2

    Topics: Animals; Antiviral Agents; Drug Repositioning; Humans; Protein Kinase Inhibitors; Virus Diseases; Viruses

2022
Kinases as Potential Therapeutic Targets for Anti-coronaviral Therapy.
    Journal of medicinal chemistry, 2022, 01-27, Volume: 65, Issue:2

    Topics: Antiviral Agents; COVID-19; COVID-19 Drug Treatment; Humans; Protein Kinase Inhibitors; SARS-CoV-2; Signal Transduction; Virus Replication

2022

Other Studies

3 other study(ies) available for sorafenib and alsterpaullone

ArticleYear
The selectivity of protein kinase inhibitors: a further update.
    The Biochemical journal, 2007, Dec-15, Volume: 408, Issue:3

    Topics: Amino Acid Sequence; Animals; Cell Line; Drug Design; Enzyme Activation; Humans; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Recombinant Proteins; Spodoptera

2007
Navigating the kinome.
    Nature chemical biology, 2011, Volume: 7, Issue:4

    Topics: Drug Design; Pharmacogenetics; Protein Kinases; Proteome; Systems Biology

2011
Recent Developments in the Use of Kinase Inhibitors for Management of Viral Infections.
    Journal of medicinal chemistry, 2022, 01-27, Volume: 65, Issue:2

    Topics: Antiviral Agents; COVID-19; COVID-19 Drug Treatment; Drug Approval; Drug Repositioning; High-Throughput Screening Assays; Humans; Protein Kinase Inhibitors; SARS-CoV-2; United States; United States Food and Drug Administration; Virus Diseases

2022