Page last updated: 2024-09-05

sorafenib and akt-i-1,2 compound

sorafenib has been researched along with akt-i-1,2 compound in 2 studies

Compound Research Comparison

Studies
(sorafenib)
Trials
(sorafenib)
Recent Studies (post-2010)
(sorafenib)
Studies
(akt-i-1,2 compound)
Trials
(akt-i-1,2 compound)
Recent Studies (post-2010) (akt-i-1,2 compound)
6,5207305,25156034

Protein Interaction Comparison

ProteinTaxonomysorafenib (IC50)akt-i-1,2 compound (IC50)
Low molecular weight phosphotyrosine protein phosphataseHomo sapiens (human)7.43
RAC-alpha serine/threonine-protein kinaseHomo sapiens (human)0.2748
RAC-beta serine/threonine-protein kinaseHomo sapiens (human)0.5861
RAC-gamma serine/threonine-protein kinaseHomo sapiens (human)1.4843

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alessi, DR; Arthur, JS; Bain, J; Cohen, P; Elliott, M; Hastie, CJ; Klevernic, I; McLauchlan, H; Plater, L; Shpiro, N1
Morphy, R1

Reviews

1 review(s) available for sorafenib and akt-i-1,2 compound

ArticleYear
Selectively nonselective kinase inhibition: striking the right balance.
    Journal of medicinal chemistry, 2010, Feb-25, Volume: 53, Issue:4

    Topics: Animals; Antineoplastic Agents; Drug Design; Drug Discovery; Humans; Protein Binding; Protein Kinase Inhibitors; Structure-Activity Relationship

2010

Other Studies

1 other study(ies) available for sorafenib and akt-i-1,2 compound

ArticleYear
The selectivity of protein kinase inhibitors: a further update.
    The Biochemical journal, 2007, Dec-15, Volume: 408, Issue:3

    Topics: Amino Acid Sequence; Animals; Cell Line; Drug Design; Enzyme Activation; Humans; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Recombinant Proteins; Spodoptera

2007