Page last updated: 2024-09-05

sorafenib and adenosine

sorafenib has been researched along with adenosine in 8 studies

Compound Research Comparison

Studies
(sorafenib)
Trials
(sorafenib)
Recent Studies (post-2010)
(sorafenib)
Studies
(adenosine)
Trials
(adenosine)
Recent Studies (post-2010) (adenosine)
6,5207305,25132,5361,0758,930

Protein Interaction Comparison

ProteinTaxonomysorafenib (IC50)adenosine (IC50)
high affinity choline transporter 1 isoform aHomo sapiens (human)0.3851
Sodium/nucleoside cotransporter 1Homo sapiens (human)5.5
Sodium/nucleoside cotransporter 2Homo sapiens (human)5.5
Adenosine receptor A3Homo sapiens (human)0.0011
Adenosine receptor A1Homo sapiens (human)0.0023
Equilibrative nucleoside transporter 1Homo sapiens (human)63
Solute carrier family 28 member 3Homo sapiens (human)3.3

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (50.00)24.3611
2020's4 (50.00)2.80

Authors

AuthorsStudies
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Ide, M; Kamikawa, T; Kashiwagi, H; Matsuo, A; Miura, T; Morikami, K; Muraoka, T; Nishihara, M1
Bar-Yehuda, S; Benjaminov, O; Ciuraru, NB; Cohen, S; Farbstein, M; Fishman, P; Fishman, S; Harpaz, Z; Kerns, WD; Medalia, G; Patoka, R; Silverman, MH; Singer, B; Stemmer, SM1
Hsiao, HH; Liu, TP; Lo, HL; Wei, LS; Yang, PM1
Alseth, I; Aukrust, P; Berges, N; Bjørås, M; Dahl, TB; Fladeby, C; Gregersen, I; Halvorsen, B; Holm, S; Klungland, A; Kong, XY; Nawaz, MS; Quiles-Jiménez, A; Segers, F; Suganthan, R; Vågbø, C; Vik, ES1
Bu, X; Chen, D; Chen, L; Chen, X; Cheng, C; He, W; Liang, H; Lin, Z; Niu, Y; Sun, L; Wan, A; Wan, G; Zhan, S; Zhang, X1
Cai, X; Cen, D; Gorshkov, K; Ji, L; Jiang, S; Liang, X; Lin, Z; Mao, Q; Tang, M; Wan, Z; Xia, S; Xu, J; Zheng, J1
Jiang, H; Lv, W; Ning, G; Wang, Y1

Reviews

1 review(s) available for sorafenib and adenosine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for sorafenib and adenosine

ArticleYear
CF102 for the treatment of hepatocellular carcinoma: a phase I/II, open-label, dose-escalation study.
    The oncologist, 2013, Volume: 18, Issue:1

    Topics: Adenosine; Adult; Aged; Apoptosis; Carcinoma, Hepatocellular; Child; Female; Humans; Leukocytes, Mononuclear; Liver Neoplasms; Male; Middle Aged; Niacinamide; Phenylurea Compounds; Purinergic P1 Receptor Agonists; Receptor, Adenosine A3; Sorafenib; Wnt Signaling Pathway

2013

Other Studies

6 other study(ies) available for sorafenib and adenosine

ArticleYear
Identification of a selective inhibitor of transforming growth factor β-activated kinase 1 by biosensor-based screening of focused libraries.
    Bioorganic & medicinal chemistry letters, 2017, 02-15, Volume: 27, Issue:4

    Topics: Biosensing Techniques; Humans; Kinetics; MAP Kinase Kinase Kinases; Protein Kinase Inhibitors; Surface Plasmon Resonance

2017
S-Adenosyl-L-methionine-competitive inhibitors of the histone methyltransferase EZH2 induce autophagy and enhance drug sensitivity in cancer cells.
    Anti-cancer drugs, 2015, Volume: 26, Issue:2

    Topics: Adenosine; Antineoplastic Combined Chemotherapy Protocols; Autophagy; Cell Line, Tumor; Cell Survival; Enhancer of Zeste Homolog 2 Protein; Enzyme Inhibitors; Gene Knockdown Techniques; Hep G2 Cells; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Humans; Indazoles; Niacinamide; Phenylurea Compounds; Polycomb Repressive Complex 2; Pyridones; S-Adenosylmethionine; Sorafenib

2015
Deletion of Endonuclease V suppresses chemically induced hepatocellular carcinoma.
    Nucleic acids research, 2020, 05-07, Volume: 48, Issue:8

    Topics: Adenosine; Animals; Antineoplastic Agents; Carcinogenesis; Cell Line; Deoxyribonuclease (Pyrimidine Dimer); Gene Expression; Humans; Inosine; Liver; Liver Neoplasms, Experimental; Mice, Knockout; RNA Editing; RNA, Transfer; Sequence Analysis, RNA; Sorafenib

2020
RNA m
    The EMBO journal, 2020, 06-17, Volume: 39, Issue:12

    Topics: Adenosine; Animals; Autophagy; Carcinoma, Hepatocellular; Drug Resistance, Neoplasm; Forkhead Box Protein O3; HEK293 Cells; Hep G2 Cells; Human Umbilical Vein Endothelial Cells; Humans; Liver Neoplasms; Male; Methylation; Methyltransferases; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Proteins; RNA, Messenger; RNA, Neoplasm; Sorafenib

2020
N
    Molecular cancer, 2020, 11-23, Volume: 19, Issue:1

    Topics: Adenosine; Animals; Antineoplastic Agents; Apoptosis; beta Catenin; Biomarkers, Tumor; Carcinoma, Hepatocellular; Cell Movement; Cell Proliferation; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; MicroRNAs; RNA, Circular; Sorafenib; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2020
Identification of an m6A-Related Signature as Biomarker for Hepatocellular Carcinoma Prognosis and Correlates with Sorafenib and Anti-PD-1 Immunotherapy Treatment Response.
    Disease markers, 2021, Volume: 2021

    Topics: Adenosine; Biomarkers, Tumor; Carcinoma, Hepatocellular; Databases, Genetic; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Immune Checkpoint Inhibitors; Liver Neoplasms; Male; Neoplasm Staging; Prognosis; Sorafenib; Treatment Outcome

2021