Compounds > sorafenib
Page last updated: 2024-09-05

sorafenib and abt-348

sorafenib has been researched along with abt-348 in 2 studies

Compound Research Comparison

Studies
(sorafenib)		Trials
(sorafenib)		Recent Studies (post-2010)
(sorafenib)		Studies
(abt-348)		Trials
(abt-348)		Recent Studies (post-2010) (abt-348)
6,5207305,251929

Protein Interaction Comparison

ProteinTaxonomysorafenib (IC50)abt-348 (IC50)
Aurora kinase AHomo sapiens (human)0.066
Tyrosine-protein kinase ABL1Homo sapiens (human)0.012
Tyrosine-protein kinase LckHomo sapiens (human)0.003
Tyrosine-protein kinase FynHomo sapiens (human)0.11
Macrophage colony-stimulating factor 1 receptorHomo sapiens (human)0.016
Proto-oncogene tyrosine-protein kinase receptor RetHomo sapiens (human)0.007
Insulin-like growth factor 1 receptorHomo sapiens (human)0.539
Platelet-derived growth factor receptor betaHomo sapiens (human)0.003
Fibroblast growth factor receptor 1Homo sapiens (human)0.188
Vascular endothelial growth factor receptor 1 Homo sapiens (human)0.032
Vascular endothelial growth factor receptor 2Homo sapiens (human)0.0028
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)1
Rho-associated protein kinase 1Homo sapiens (human)0.456
Aurora kinase BHomo sapiens (human)0.007
ALK tyrosine kinase receptorHomo sapiens (human)0.363
Aurora kinase CHomo sapiens (human)0.007

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hajduk, PJ; Johnson, EF; Kifle, L; Merta, PJ; Metz, JT; Soni, NB1
Eriksson, LA; Gao, C; Grøtli, M1

Other Studies

2 other study(ies) available for sorafenib and abt-348

ArticleYear
Navigating the kinome.
    Nature chemical biology, 2011, Volume: 7, Issue:4

    Topics: Drug Design; Pharmacogenetics; Protein Kinases; Proteome; Systems Biology

2011
Characterization of interactions and pharmacophore development for DFG-out inhibitors to RET tyrosine kinase.
    Journal of molecular modeling, 2015, Volume: 21, Issue:7

    Topics: Aminopyridines; Binding Sites; Humans; Indoles; Kinetics; Molecular Docking Simulation; Molecular Dynamics Simulation; Naphthalenes; Niacinamide; Oligonucleotides; Phenylurea Compounds; Protein Binding; Protein Conformation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-ret; Pyrazoles; Sorafenib; Structural Homology, Protein; Thermodynamics; Vascular Endothelial Growth Factor Receptor-2

2015