sorafenib has been researched along with 2-amino-6-methyl-4-(3-pyridinyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile in 2 studies
| Studies (sorafenib) | Trials (sorafenib) | Recent Studies (post-2010) (sorafenib) | Studies (2-amino-6-methyl-4-(3-pyridinyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile) | Trials (2-amino-6-methyl-4-(3-pyridinyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile) | Recent Studies (post-2010) (2-amino-6-methyl-4-(3-pyridinyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile) |
|---|---|---|---|---|---|
| 6,520 | 730 | 5,251 | 9 | 0 | 4 |
| Protein | Taxonomy | sorafenib (IC50) | 2-amino-6-methyl-4-(3-pyridinyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile (IC50) |
|---|---|---|---|
| Cyclin-C | Homo sapiens (human) | 0.3555 | |
| Cyclin-dependent kinase 8 | Homo sapiens (human) | 0.4277 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kumarasiri, M; Philip, S; Teo, T; Wang, S; Yu, M | 1 |
| Cai, T; Chen, T; Du, K; Gao, X; Luo, X; Shen, R; Sun, H; Wu, C; Wu, Y; Xi, M; Yu, L | 1 |
2 review(s) available for sorafenib and 2-amino-6-methyl-4-(3-pyridinyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile
| Article | Year |
|---|---|
Cyclin-Dependent Kinase 8: A New Hope in Targeted Cancer Therapy?
Topics: Antineoplastic Agents; Cyclin-Dependent Kinase 8; Cytokines; Humans; Male; Molecular Targeted Therapy; Neoplasms; Phosphorylation; Protein Kinase Inhibitors; Transcription Factors; Tumor Escape | 2018 |
CDK8 as a therapeutic target for cancers and recent developments in discovery of CDK8 inhibitors.
Topics: Colorectal Neoplasms; Cyclin-Dependent Kinase 8; Drug Discovery; Humans; Mediator Complex; Molecular Structure; Neoplasms; Oncogenes; Protein Kinase Inhibitors; Wnt Signaling Pathway | 2019 |