Compounds > sorafenib
Page last updated: 2024-09-05

sorafenib and 2-((4-pyridyl)methyl)amino-n-(3-(trifluoromethyl)phenyl)benzamide

sorafenib has been researched along with 2-((4-pyridyl)methyl)amino-n-(3-(trifluoromethyl)phenyl)benzamide in 2 studies

Compound Research Comparison

Studies
(sorafenib)		Trials
(sorafenib)		Recent Studies (post-2010)
(sorafenib)		Studies
(2-((4-pyridyl)methyl)amino-n-(3-(trifluoromethyl)phenyl)benzamide)		Trials
(2-((4-pyridyl)methyl)amino-n-(3-(trifluoromethyl)phenyl)benzamide)		Recent Studies (post-2010) (2-((4-pyridyl)methyl)amino-n-(3-(trifluoromethyl)phenyl)benzamide)
6,5207305,2511703

Protein Interaction Comparison

ProteinTaxonomysorafenib (IC50)2-((4-pyridyl)methyl)amino-n-(3-(trifluoromethyl)phenyl)benzamide (IC50)
Tyrosine-protein kinase ABL1Homo sapiens (human)2.82
Macrophage colony-stimulating factor 1 receptorHomo sapiens (human)0.38
Platelet-derived growth factor receptor betaHomo sapiens (human)0.64
Mast/stem cell growth factor receptor KitHomo sapiens (human)0.236
Vascular endothelial growth factor receptor 1 Homo sapiens (human)0.1365
Vascular endothelial growth factor receptor 3Homo sapiens (human)0.018
Vascular endothelial growth factor receptor 2Homo sapiens (human)0.0506

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gray, NS; Liu, Y1
Jeong, KW; Kim, MS; Kim, Y; Lee, GS; Lee, K; Lee, Y; Song, JY1

Other Studies

2 other study(ies) available for sorafenib and 2-((4-pyridyl)methyl)amino-n-(3-(trifluoromethyl)phenyl)benzamide

ArticleYear
Rational design of inhibitors that bind to inactive kinase conformations.
    Nature chemical biology, 2006, Volume: 2, Issue:7

    Topics: Binding Sites; Drug Design; Humans; Models, Molecular; Phosphotransferases; Protein Kinase Inhibitors; Protein Structure, Tertiary

2006
Pharmacophore modeling and virtual screening studies for new VEGFR-2 kinase inhibitors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:11

    Topics: Drug Evaluation, Preclinical; Models, Molecular; Protein Kinase Inhibitors; Vascular Endothelial Growth Factor Receptor-2

2010