sorafenib has been researched along with 1-(3-tert-butyl-1-methylpyrazol-5-yl)-3-(4-chlorophenyl)urea in 2 studies
| Studies (sorafenib) | Trials (sorafenib) | Recent Studies (post-2010) (sorafenib) | Studies (1-(3-tert-butyl-1-methylpyrazol-5-yl)-3-(4-chlorophenyl)urea) | Trials (1-(3-tert-butyl-1-methylpyrazol-5-yl)-3-(4-chlorophenyl)urea) | Recent Studies (post-2010) (1-(3-tert-butyl-1-methylpyrazol-5-yl)-3-(4-chlorophenyl)urea) |
|---|---|---|---|---|---|
| 6,520 | 730 | 5,251 | 13 | 0 | 1 |
| Protein | Taxonomy | sorafenib (IC50) | 1-(3-tert-butyl-1-methylpyrazol-5-yl)-3-(4-chlorophenyl)urea (IC50) |
|---|---|---|---|
| Mitogen-activated protein kinase 14 | Homo sapiens (human) | 0.7943 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gray, NS; Liu, Y | 1 |
| Getlik, M; Grütter, C; Klüter, S; Naqvi, T; Pawar, V; Rabiller, M; Rauh, D; Simard, JR | 1 |
2 other study(ies) available for sorafenib and 1-(3-tert-butyl-1-methylpyrazol-5-yl)-3-(4-chlorophenyl)urea
| Article | Year |
|---|---|
Rational design of inhibitors that bind to inactive kinase conformations.
Topics: Binding Sites; Drug Design; Humans; Models, Molecular; Phosphotransferases; Protein Kinase Inhibitors; Protein Structure, Tertiary | 2006 |
Displacement assay for the detection of stabilizers of inactive kinase conformations.
Topics: Crystallography, X-Ray; Drug Design; Mitogen-Activated Protein Kinase 9; Models, Molecular; p38 Mitogen-Activated Protein Kinases; Protein Conformation; Protein Kinase Inhibitors; Pyrazoles; Structure-Activity Relationship; Urea | 2010 |