sophoramine has been researched along with clonidine in 1 studies
*Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION. [MeSH]
*Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION. [MeSH]
| Studies (sophoramine) | Trials (sophoramine) | Recent Studies (post-2010) (sophoramine) | Studies (clonidine) | Trials (clonidine) | Recent Studies (post-2010) (clonidine) |
|---|---|---|---|---|---|
| 15 | 0 | 5 | 13,692 | 2,044 | 1,394 |
| Protein | Taxonomy | sophoramine (IC50) | clonidine (IC50) |
|---|---|---|---|
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 0.101 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 0.0353 | |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | 0.0115 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 5.365 | |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0173 | |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0173 | |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0173 | |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | 1.21 | |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | 5.365 | |
| Alpha-2A adrenergic receptor | Bos taurus (cattle) | 0.002 | |
| Nischarin | Rattus norvegicus (Norway rat) | 0.3662 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bian, K; Toda, N | 1 |
1 other study(ies) available for sophoramine and clonidine
| Article | Year |
|---|---|
Effects of sophoramine, an alkaloid from Sophora alopecuroides on isolated dog blood vessels.
Topics: Adrenergic Fibers; Alkaloids; Animals; Cerebral Arteries; Clonidine; Coronary Vessels; Dinoprost; Dogs; Dose-Response Relationship, Drug; Female; Male; Mesenteric Arteries; Mesenteric Veins; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Vasodilator Agents; Yohimbine | 1988 |