sophocarpine has been researched along with oxymatrine in 20 studies
| Studies (sophocarpine) | Trials (sophocarpine) | Recent Studies (post-2010) (sophocarpine) | Studies (oxymatrine) | Trials (oxymatrine) | Recent Studies (post-2010) (oxymatrine) |
|---|---|---|---|---|---|
| 94 | 0 | 61 | 41 | 0 | 27 |
| 94 | 0 | 61 | 412 | 16 | 270 |
| Protein | Taxonomy | sophocarpine (IC50) | oxymatrine (IC50) |
|---|---|---|---|
| Pyruvate kinase PKM | Homo sapiens (human) | 5 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (10.00) | 18.7374 |
| 1990's | 3 (15.00) | 18.2507 |
| 2000's | 5 (25.00) | 29.6817 |
| 2010's | 10 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, DF; Ding, PL; Huang, H; Liao, ZX; Zhou, P | 1 |
| Bi, CW; Du, NN; Gao, LM; Han, YX; Jiang, JD; Li, X; Li, YH; Peng, ZG; Shan, YQ; Song, DQ; Wang, YP; Zhang, T | 1 |
| Hua, J; Huang, FP; Li, YH; Liang, D; Pan, QM; Wang, HS | 1 |
| Bai, L; Guan, F; Liu, J; Pan, X; Yang, Y; Zhang, L | 1 |
| Ba, YK; Wang, YL | 1 |
| Cui, JF; Wang, MZ; Zhang, GD | 1 |
| Li, J; Omiya, S; Wang, X; Wei, L | 1 |
| Ji, X; Lao, Q; Li, J; Wang, X; Yan, Y | 1 |
| Jiang, J; Xu, X | 1 |
| Ma, RL; Sheng, LS; Yu, XS; Zhou, HH | 1 |
| Cheng, Y; Shao, Q; Wu, Y; Zhen, Z | 1 |
| Hu, JH; Liu, JY; Peng, C; Qin, Z; Wang, J; Zhu, QG | 1 |
| Hu, Z; Li, Y; Wang, S; Xiao, Z; Zhang, J; Zhang, Y | 1 |
| Huang, CF; Jiang, J; Lin, Z; Liu, XS | 1 |
| Funaya, N; Haginaka, J | 1 |
| Chen, J; Liang, SW; Meng, J; Sun, F; Wang, SM | 1 |
| Gao, HM; Liu, XQ; Wan, KY; Wang, ZM; Zhang, QW; Zhao, FC | 1 |
| Han, Y; Li, X; Wang, Q; Xu, J; Zhang, D; Zhang, X | 1 |
| Guo, Y; Liu, F; Liu, Z; Lv, Y; Pan, S; Qiu, C; Wang, J; Yang, T; Zhang, Y; Zhu, L | 1 |
| Cheng, Q; Sun, G; Sun, X; Wang, M; Wang, R; Wang, S; Xie, X; Yang, K; Ye, J; Zhou, P | 1 |
1 review(s) available for sophocarpine and oxymatrine
| Article | Year |
|---|---|
[Progress in the study of antineoplastic activity of suphora flarescens ait and its alkaloids].
Topics: Alkaloids; Animals; Antineoplastic Agents, Phytogenic; Fabaceae; Humans; Matrines; Plants, Medicinal; Quinolizines | 1998 |
19 other study(ies) available for sophocarpine and oxymatrine
| Article | Year |
|---|---|
(+)-12alpha-Hydroxysophocarpine, a new quinolizidine alkaloid and related anti-HBV alkaloids from Sophora flavescens.
Topics: Alkaloids; Antigens, Viral; Antiviral Agents; Cell Line, Tumor; Hepatitis B virus; Humans; Magnetic Resonance Spectroscopy; Molecular Structure; Plants, Medicinal; Quinolizines; Sophora; Structure-Activity Relationship | 2006 |
Design and synthesis of oxymatrine analogues overcoming drug resistance in hepatitis B virus through targeting host heat stress cognate 70.
Topics: Administration, Oral; Alkaloids; Animals; Antiviral Agents; Down-Regulation; Drug Design; Drug Resistance, Viral; Hep G2 Cells; Hepatitis B virus; HSC70 Heat-Shock Proteins; Humans; Lamivudine; Lethal Dose 50; Mice; Molecular Conformation; Quinolizines; RNA, Messenger; Structure-Activity Relationship | 2011 |
Antiviral Matrine-Type Alkaloids from the Rhizomes of Sophora tonkinensis.
Topics: Alkaloids; Antiviral Agents; Influenza A Virus, H3N2 Subtype; Inhibitory Concentration 50; Matrines; Molecular Structure; Quinolizines; Rhizome; Sophora; Stereoisomerism | 2015 |
Quinolizidine alkaloids reduced mortality in EV71-infected mice by compensating for the levels of T cells.
Topics: Alkaloids; Animals; Antiviral Agents; Enterovirus A, Human; Hand, Foot and Mouth Disease; Humans; Mice, Inbred BALB C; Quinolizidines; Structure-Activity Relationship; T-Lymphocytes | 2015 |
Electrophysiologic observation of the effects of Matrine Co against arrhythmia induced by Chinese cobra venom on isolated rat sinus node and papillary muscles.
Topics: Action Potentials; Alkaloids; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Elapid Venoms; Electrophysiology; Female; In Vitro Techniques; Male; Matrines; Myocardial Contraction; Naphthyridines; Papillary Muscles; Quinolizines; Rats; Sinoatrial Node | 1987 |
[HPLC and TLC-densitometry determination of alkaloidal constituents in Sophora flavescens and Sophora lopecuroides].
Topics: Alkaloids; Anthelmintics; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Densitometry; Fabaceae; Matrines; Medicine, Chinese Traditional; Medicine, East Asian Traditional; Naphthyridines; Phytotherapy; Plants, Medicinal; Quinolizines | 1985 |
[Alkaloid constituents in the seeds of Sophora viciifolia Hance].
Topics: Alkaloids; Drugs, Chinese Herbal; Fabaceae; Plants, Medicinal; Quinolizines | 1995 |
[Alkaloids in the flowers of Sophora viciifolia Hance].
Topics: Alkaloids; Anti-Inflammatory Agents, Non-Steroidal; Drugs, Chinese Herbal; Fabaceae; Matrines; Plants, Medicinal; Quinolizines | 1996 |
[Study on the fingerprints of the alkaloids in Sophora flavescens].
Topics: Alkaloids; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Injections; Matrines; Molecular Weight; Plant Roots; Plants, Medicinal; Quinolizines; Sophora; Spectrometry, Mass, Electrospray Ionization | 2003 |
Determination of quinolizidine alkaloids in Sophora flavescens and its preparation using capillary electrophoresis.
Topics: Alkaloids; Electrophoresis, Capillary; Matrines; Molecular Structure; Plant Preparations; Quinolizines; Reproducibility of Results; Sophora | 2006 |
[Studies on cutaneous permeation in vitro of Kushen recipe gel].
Topics: Administration, Cutaneous; Alkaloids; Animals; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Female; Gels; In Vitro Techniques; Matrines; Quinolizines; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Skin; Skin Absorption | 2007 |
Sophocarpine and matrine inhibit the production of TNF-alpha and IL-6 in murine macrophages and prevent cachexia-related symptoms induced by colon26 adenocarcinoma in mice.
Topics: Adenocarcinoma; Alkaloids; Animals; Cachexia; Cell Line; Colonic Neoplasms; Interleukin-6; Lipopolysaccharides; Macrophages; Male; Matrines; Mice; Mice, Inbred BALB C; Quinolizines; Tumor Necrosis Factor-alpha | 2008 |
In vitro anti-tumour activities of quinolizidine alkaloids derived from Sophora flavescens Ait.
Topics: Alkaloids; Antineoplastic Agents; Apoptosis; Azocines; Drugs, Chinese Herbal; Electrophoresis, Capillary; HL-60 Cells; Humans; Inhibitory Concentration 50; K562 Cells; Matrines; Phytotherapy; Piperidines; Plant Preparations; Plant Roots; Quinolizidines; Quinolizines; Sophora | 2011 |
Matrine- and oxymatrine-imprinted monodisperse polymers prepared by precipitation polymerization and their applications for the selective extraction of matrine-type alkaloids from Sophora flavescens Aiton.
Topics: Alkaloids; Chemical Precipitation; Matrines; Molecular Imprinting; Plant Roots; Polymerization; Polymers; Quinolizines; Sophora | 2012 |
[Simultaneous quantitative analysis of five alkaloids in Sophora flavescens by multi-components assay by single marker].
Topics: Alkaloids; Matrines; Quinolizines; Sophora | 2013 |
[Rapid determination of the multi-marker ingredients in Heterosmilacis Japonicae Rhizoma and Sophorae Flavescentis Radix with near-infrared diffused reflection spectroscopy].
Topics: Alkaloids; Calibration; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Least-Squares Analysis; Matrines; Plant Roots; Quinolizines; Smilacaceae; Sophora; Spectroscopy, Near-Infrared | 2014 |
Comprehensive two-dimensional PC-3 prostate cancer cell membrane chromatography for screening anti-tumor components from Radix Sophorae flavescentis.
Topics: Alkaloids; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Membrane; China; Chromatography, High Pressure Liquid; Drug Screening Assays, Antitumor; Drugs, Chinese Herbal; Flavonoids; Humans; Male; Matrines; Propiophenones; Prostatic Neoplasms; Quinolizines; Sophora | 2017 |
Matrine-Type Alkaloids Inhibit Advanced Glycation End Products Induced Reactive Oxygen Species-Mediated Apoptosis of Aortic Endothelial Cells In Vivo and In Vitro by Targeting MKK3 and p38MAPK Signaling.
Topics: Alkaloids; Animals; Antioxidants; Apoptosis; Cells, Cultured; Cytoprotection; Dose-Response Relationship, Drug; Endothelial Cells; Glycation End Products, Advanced; Male; MAP Kinase Kinase 3; MAP Kinase Kinase 6; Matrines; NF-E2-Related Factor 2; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Quinolizines; Rats, Sprague-Dawley; Reactive Oxygen Species; Serum Albumin, Bovine; Signal Transduction | 2017 |
An integrated characterization of contractile, electrophysiological, and structural cardiotoxicity of Sophora tonkinensis Gapnep. in human pluripotent stem cell-derived cardiomyocytes.
Topics: Alkaloids; Azocines; Cardiotoxicity; Cell Differentiation; Cell Proliferation; Cell Survival; Electric Impedance; Extracellular Fluid; Humans; Induced Pluripotent Stem Cells; Matrines; Myocardial Contraction; Myocytes, Cardiac; Quinolizines; Reactive Oxygen Species; Sophora | 2019 |