sonepiprazole has been researched along with l 745870 in 5 studies
| Studies (sonepiprazole) | Trials (sonepiprazole) | Recent Studies (post-2010) (sonepiprazole) | Studies (l 745870) | Trials (l 745870) | Recent Studies (post-2010) (l 745870) |
|---|---|---|---|---|---|
| 20 | 1 | 5 | 92 | 0 | 29 |
| Protein | Taxonomy | sonepiprazole (IC50) | l 745870 (IC50) |
|---|---|---|---|
| Voltage-dependent L-type calcium channel subunit alpha-1F | Homo sapiens (human) | 9 | |
| D(4) dopamine receptor | Homo sapiens (human) | 0.4785 | |
| Voltage-dependent L-type calcium channel subunit alpha-1D | Homo sapiens (human) | 9 | |
| Voltage-dependent L-type calcium channel subunit alpha-1S | Homo sapiens (human) | 9 | |
| Voltage-dependent L-type calcium channel subunit alpha-1C | Homo sapiens (human) | 9 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Braun, J; Brodbeck, R; Kieltyka, A; Thurkauf, A; Zhao, H | 1 |
| Bristow, LJ; Hutson, PH; Rowley, M | 1 |
| Hopkins, CR; Lindsley, CW | 1 |
| Capiris, T; Connor, DT; Heffner, TG; MacKenzie, RG; Miller, SR; Pugsley, TA; Unangst, PC; Wise, LD | 1 |
| Brooks, EW; Mansbach, RS; Sanner, MA; Zorn, SH | 1 |
2 review(s) available for sonepiprazole and l 745870
| Article | Year |
|---|---|
Current and novel approaches to the drug treatment of schizophrenia.
Topics: Animals; Antipsychotic Agents; Cholinergic Agonists; Disease Models, Animal; Dopamine Antagonists; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Humans; Mice; Mice, Transgenic; Nitric Oxide Synthase; Receptor, Serotonin, 5-HT2A; Receptors, AMPA; Receptors, Dopamine D2; Receptors, Dopamine D4; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotensin; Receptors, Serotonin; Schizophrenia; Serotonin Antagonists | 2001 |
Return of D
Topics: Animals; Drug Discovery; Humans; Ligands; Molecular Targeted Therapy; Neoplasms; Parkinson Disease; Receptors, Dopamine D4; Small Molecule Libraries; Substance-Related Disorders | 2017 |
3 other study(ies) available for sonepiprazole and l 745870
| Article | Year |
|---|---|
Design, synthesis, and discovery of 3-piperazinyl-3,4-dihydro-2(1H)-quinolinone derivatives: a novel series of mixed dopamine D2/D4 receptor antagonists.
Topics: Antipsychotic Agents; Clozapine; Dopamine D2 Receptor Antagonists; Humans; Lactams; Piperazines; Protein Binding; Quinolones; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Dopamine D4; Structure-Activity Relationship | 2000 |
Chromeno[3,4-c]pyridin-5-ones: selective human dopamine D4 receptor antagonists as potential antipsychotic agents.
Topics: Animals; Antipsychotic Agents; CHO Cells; Cloning, Molecular; Cricetinae; Dopamine D2 Receptor Antagonists; Humans; Kinetics; Levodopa; Models, Chemical; Piperazines; Pyridines; Pyridones; Pyrroles; Rats; Receptors, Dopamine D2; Receptors, Dopamine D4; Structure-Activity Relationship; Sulfonamides | 1997 |
Selective dopamine D4 receptor antagonists reverse apomorphine-induced blockade of prepulse inhibition.
Topics: Animals; Apomorphine; Cell Line; Dopamine Antagonists; Humans; Male; Piperazines; Pyrazines; Pyridines; Pyrimidines; Pyrroles; Rats; Rats, Wistar; Receptors, Dopamine D2; Receptors, Dopamine D4; Reflex, Startle; Sulfonamides | 1998 |