sonepiprazole has been researched along with cp 293019 in 5 studies
| Studies (sonepiprazole) | Trials (sonepiprazole) | Recent Studies (post-2010) (sonepiprazole) | Studies (cp 293019) | Trials (cp 293019) | Recent Studies (post-2010) (cp 293019) |
|---|---|---|---|---|---|
| 20 | 1 | 5 | 9 | 0 | 1 |
| Protein | Taxonomy | sonepiprazole (IC50) | cp 293019 (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 0.15 | |
| 5-hydroxytryptamine receptor 1A | Mus musculus (house mouse) | 0.18 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Braun, J; Brodbeck, R; Kieltyka, A; Thurkauf, A; Zhao, H | 1 |
| Bristow, LJ; Hutson, PH; Rowley, M | 1 |
| Gmeiner, P; Kortagere, S; Schetz, JA; Weinstein, H | 1 |
| Hopkins, CR; Lindsley, CW | 1 |
| Brooks, EW; Mansbach, RS; Sanner, MA; Zorn, SH | 1 |
2 review(s) available for sonepiprazole and cp 293019
| Article | Year |
|---|---|
Current and novel approaches to the drug treatment of schizophrenia.
Topics: Animals; Antipsychotic Agents; Cholinergic Agonists; Disease Models, Animal; Dopamine Antagonists; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Humans; Mice; Mice, Transgenic; Nitric Oxide Synthase; Receptor, Serotonin, 5-HT2A; Receptors, AMPA; Receptors, Dopamine D2; Receptors, Dopamine D4; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotensin; Receptors, Serotonin; Schizophrenia; Serotonin Antagonists | 2001 |
Return of D
Topics: Animals; Drug Discovery; Humans; Ligands; Molecular Targeted Therapy; Neoplasms; Parkinson Disease; Receptors, Dopamine D4; Small Molecule Libraries; Substance-Related Disorders | 2017 |
3 other study(ies) available for sonepiprazole and cp 293019
| Article | Year |
|---|---|
Design, synthesis, and discovery of 3-piperazinyl-3,4-dihydro-2(1H)-quinolinone derivatives: a novel series of mixed dopamine D2/D4 receptor antagonists.
Topics: Antipsychotic Agents; Clozapine; Dopamine D2 Receptor Antagonists; Humans; Lactams; Piperazines; Protein Binding; Quinolones; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Dopamine D4; Structure-Activity Relationship | 2000 |
Certain 1,4-disubstituted aromatic piperidines and piperazines with extreme selectivity for the dopamine D4 receptor interact with a common receptor microdomain.
Topics: Animals; Binding Sites; Chlorocebus aethiops; COS Cells; Mutagenesis, Site-Directed; Piperazines; Piperidines; Radioligand Assay; Rats; Receptors, Dopamine D2; Receptors, Dopamine D4; Recombinant Proteins; Structure-Activity Relationship | 2004 |
Selective dopamine D4 receptor antagonists reverse apomorphine-induced blockade of prepulse inhibition.
Topics: Animals; Apomorphine; Cell Line; Dopamine Antagonists; Humans; Male; Piperazines; Pyrazines; Pyridines; Pyrimidines; Pyrroles; Rats; Rats, Wistar; Receptors, Dopamine D2; Receptors, Dopamine D4; Reflex, Startle; Sulfonamides | 1998 |