Page last updated: 2024-08-18

soman and scopolamine hydrobromide

soman has been researched along with scopolamine hydrobromide in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19905 (16.67)18.7374
1990's11 (36.67)18.2507
2000's9 (30.00)29.6817
2010's4 (13.33)24.3611
2020's1 (3.33)2.80

Authors

AuthorsStudies
Adams, N; Corcoran, K; Kaminskis, A; Maitland, G; von Bredow, J; Wade, J1
Anderson, DR; Harris, LW; Lennox, WJ; Solana, RP2
Chen, J; Cheng, GF; Jiang, ZH; Wang, LP; Zhou, TC1
Ho, IK; Hoskins, B; Ito, Y; Lim, DK; Yu, ZJ1
Aas, P; Fonnum, F; Malmei, T1
Sidell, FR1
Dochterman, LW; McDonough, JH; Shih, TM; Smith, CD1
Wetherell, JR1
Anderson, DR; Bowersox, SL; Carter, WH; Gennings, C; Harris, LW; Lennox, WJ; Solana, RP2
Anders, JC; Anderson, DR; Bowersox, SL; Harris, LW; Lennox, WJ1
Beers, ET; Brennecke, LH; Sparenborg, S1
Anderson, DR; Baze, WB; Byers, SL; Capacio, BR; Chang, FC; Harris, LW; Lennox, WJ1
Bruijnzeel, PL; Busker, RW; Melchers, BP; Olivier, B; Philippens, IH; Wolthuis, OL1
Alkalay, D; Chapman, S; Cohen, G; Gilat, E; Rabinovitz, I; Raveh, L; Weissman, BA1
Bruijnzeel, PL; Melchers, BP; Olivier, B; Philippens, IH1
Fusek, J; Kassa, J1
Baubichon, D; Carpentier, P; Dorandeu, F; Foquin, A; Lallement, G1
Alkalay, D; Brandeis, R; Cohen, G; Rabinovitz, I; Raveh, L; Sonego, H; Weissman, BA1
Bowditch, AP; Crofts, HS; Muggleton, NG; Pearce, PC; Scott, EA1
Aas, P; Enger, S; Myhrer, T3
Aas, P; Andersen, JM; Myhrer, T; Nguyen, NH1
Joosen, MJ; Philippens, IH; Vanwersch, RA1
Hassel, B1
Doctor, BP; Morthole, V; Nambiar, MP; Oguntayo, S; Perkins, MW; Pierre, Z; Rezk, P; Sciuto, AM; Song, J1
McDonough, JH; Shih, TM; Skovira, JW1
Capacio, BR; McDonough, JH; McMonagle, JD1

Trials

2 trial(s) available for soman and scopolamine hydrobromide

ArticleYear
Soman and sarin: clinical manifestations and treatment of accidental poisoning by organophosphates.
    Clinical toxicology, 1974, Volume: 7, Issue:1

    Topics: Adult; Antidotes; Atropine; Cholinesterase Inhibitors; Cholinesterases; Cyanosis; Depression; Electrocardiography; Epistaxis; Humans; Insecticides; Male; Mental Disorders; Middle Aged; Placebos; Pralidoxime Compounds; Pyridinium Compounds; Respiration; Sarin; Scopolamine; Soman; Sulfisoxazole; Tachycardia; Time Factors

1974
Caramiphen and scopolamine prevent soman-induced brain damage and cognitive dysfunction.
    Neurotoxicology, 2002, Volume: 23, Issue:1

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cognition Disorders; Cyclopentanes; Escape Reaction; Hypoxia, Brain; Male; Maze Learning; Prosencephalon; Rats; Rats, Sprague-Dawley; Reaction Time; Scopolamine; Soman; Swimming

2002

Other Studies

28 other study(ies) available for soman and scopolamine hydrobromide

ArticleYear
Efficacy evaluation of physostigmine and anticholinergic adjuncts as a pretreatment for nerve agent intoxication.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1991, Volume: 17, Issue:4

    Topics: Animals; Cholinesterases; Erythrocytes; Female; Lethal Dose 50; Macaca fascicularis; Male; Nervous System Diseases; Parasympatholytics; Physostigmine; Scopolamine; Soman; Trihexyphenidyl

1991
Effects of subacute pretreatment with carbamate together with acute adjunct pretreatment against nerve agent exposure.
    Drug and chemical toxicology, 1991, Volume: 14, Issue:1-2

    Topics: Animals; Carbamates; Cholinesterase Inhibitors; Female; Guinea Pigs; Lethal Dose 50; Male; Mice; Organothiophosphorus Compounds; Physostigmine; Scopolamine; Soman; Trihexyphenidyl

1991
[Effects of anticonvulsants on the cyclic nucleotide content of the plasma and cerebellum of convulsive rats].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1987, Volume: 8, Issue:3

    Topics: Animals; Anticonvulsants; Cerebellum; Clonazepam; Cyclic AMP; Cyclic GMP; Diazepam; Male; Organophosphorus Compounds; Rats; Scopolamine; Seizures; Soman

1987
Effects of subacute administration of physostigmine on blood acetylcholinesterase activity, motor performance, and soman intoxication.
    Toxicology and applied pharmacology, 1989, Volume: 97, Issue:2

    Topics: Acetylcholinesterase; Animals; Male; Motor Activity; Physostigmine; Rats; Scopolamine; Soman

1989
Prevention of soman toxicity after the continuous administration of physostigmine.
    Pharmacology, biochemistry, and behavior, 1988, Volume: 31, Issue:3

    Topics: Acetylcholinesterase; Animals; Brain; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Synergism; Guinea Pigs; Infusion Pumps; Male; Physostigmine; Scopolamine; Soman; Time Factors

1988
The effect of soman on potassium evoked 3H-acetylcholine release in the isolated rat bronchi.
    Pharmacology & toxicology, 1987, Volume: 60, Issue:3

    Topics: Acetylcholine; Acetylcholinesterase; Animals; Bronchi; In Vitro Techniques; Male; Muscle, Smooth; Nerve Endings; Parasympathetic Nervous System; Potassium; Rats; Rats, Inbred Strains; Scopolamine; Soman

1987
Protection against nerve agent-induced neuropathology, but not cardiac pathology, is associated with the anticonvulsant action of drug treatment.
    Neurotoxicology, 1995,Spring, Volume: 16, Issue:1

    Topics: Animals; Anticonvulsants; Atropine; Brain; Diazepam; Heart; Male; Myocardium; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Scopolamine; Seizures; Soman; Time Factors

1995
Continuous administration of low dose rates of physostigmine and hyoscine to guinea-pigs prevents the toxicity and reduces the incapacitation produced by soman poisoning.
    The Journal of pharmacy and pharmacology, 1994, Volume: 46, Issue:12

    Topics: Acetylcholinesterase; Animals; Cerebellum; Cerebral Cortex; Cholinesterase Inhibitors; Corpus Striatum; Dose-Response Relationship, Drug; Drug Interactions; Erythrocytes; Guinea Pigs; Hippocampus; Infusion Pumps, Implantable; Male; Medulla Oblongata; Mesencephalon; Osmosis; Physostigmine; Poisoning; Scopolamine; Soman

1994
Efficacy comparison of scopolamine and diazepam against soman-induced debilitation in guinea pigs.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1994, Volume: 22, Issue:4

    Topics: Animals; Diazepam; Guinea Pigs; Male; Models, Statistical; Scopolamine; Seizures; Soman

1994
Efficacy of injectable anticholinergic drugs against soman-induced convulsive/subconvulsive activity.
    Drug and chemical toxicology, 1994, Volume: 17, Issue:2

    Topics: Animals; Diazepam; Guinea Pigs; Injections, Intramuscular; Male; Parasympatholytics; Random Allocation; Scopolamine; Seizures; Soman

1994
Efficacy comparison of scopolamine (SCP) and diazepam (DZ) against soman-induced lethality in guinea pigs.
    Drug and chemical toxicology, 1994, Volume: 17, Issue:1

    Topics: Animals; Antidotes; Diazepam; Guinea Pigs; Male; Models, Statistical; Probability; Scopolamine; Soman

1994
Pharmacological dissociation of the motor and electrical aspects of convulsive status epilepticus induced by the cholinesterase inhibitor soman.
    Epilepsy research, 1993, Volume: 14, Issue:2

    Topics: Analysis of Variance; Animals; Antidotes; Atropine; Brain; Cholinesterase Inhibitors; Diazepam; Electroencephalography; Guinea Pigs; Image Processing, Computer-Assisted; Male; Pralidoxime Compounds; Pyridostigmine Bromide; Scopolamine; Soman; Status Epilepticus

1993
Antagonism of soman-induced convulsions by midazolam, diazepam and scopolamine.
    Drug and chemical toxicology, 1997, Volume: 20, Issue:3

    Topics: Animals; Anticonvulsants; Brain; Chemical Warfare Agents; Cholinesterase Inhibitors; Convulsants; Diazepam; Electroencephalography; Electromyography; GABA Modulators; Male; Midazolam; Muscarinic Antagonists; Rats; Rats, Sprague-Dawley; Scopolamine; Seizures; Soman

1997
Subchronic physostigmine pretreatment in guinea pigs: effective against soman and without side effects.
    Pharmacology, biochemistry, and behavior, 1998, Volume: 59, Issue:4

    Topics: Acetylcholinesterase; Animals; Avoidance Learning; Cholinesterase Inhibitors; Electroencephalography; Electrophysiology; Evoked Potentials, Visual; Guinea Pigs; Male; Muscarinic Antagonists; Physostigmine; Receptors, Cholinergic; Receptors, Muscarinic; Reflex, Startle; Scopolamine; Soman

1998
The involvement of the NMDA receptor complex in the protective effect of anticholinergic drugs against soman poisoning.
    Neurotoxicology, 1999, Volume: 20, Issue:4

    Topics: Animals; Brain; Cholinesterase Inhibitors; Cyclopentanes; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Electroencephalography; Excitatory Amino Acid Antagonists; Flunitrazepam; In Vitro Techniques; Male; Mice; Mice, Inbred ICR; Parasympatholytics; Protein Binding; Pyridostigmine Bromide; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Scopolamine; Seizures; Soman; Time Factors

1999
Scopolamine augments the efficacy of physostigmine against soman poisoning in guinea pigs.
    Pharmacology, biochemistry, and behavior, 2000, Jan-01, Volume: 65, Issue:1

    Topics: Animals; Cholinesterase Inhibitors; Drug Synergism; Electroencephalography; Guinea Pigs; Male; Muscarinic Antagonists; Physostigmine; Reflex, Startle; Scopolamine; Soman

2000
The influence of anticholinergic drug selection on the efficacy of antidotal treatment of soman-poisoned rats.
    Toxicology, 2000, Nov-23, Volume: 154, Issue:1-3

    Topics: Animals; Antidotes; Atropine; Benactyzine; Biperiden; Blood Pressure; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Electrocardiography; Heart Rate; Male; Muscarinic Antagonists; Oximes; Pyridinium Compounds; Rats; Scopolamine; Soman

2000
Subchronic administration of various pretreatments of nerve agent poisoning. II. Compared efficacy against soman toxicity.
    Drug and chemical toxicology, 2001, Volume: 24, Issue:2

    Topics: Alkaloids; Animals; Cholinesterase Inhibitors; Electroencephalography; Guinea Pigs; Male; Neuroprotective Agents; Physostigmine; Pyridostigmine Bromide; Scopolamine; Seizures; Sesquiterpenes; Soman; Time Factors

2001
Assessment of a combination of physostigmine and scopolamine as pretreatment against the behavioural effects of organophosphates in the common marmoset (Callithrix jacchus).
    Psychopharmacology, 2003, Volume: 166, Issue:3

    Topics: Animals; Behavior, Animal; Callithrix; Cholinesterase Inhibitors; Discrimination Learning; Drug Implants; Drug Interactions; Female; Male; Muscarinic Antagonists; Organophosphorus Compounds; Physostigmine; Reversal Learning; Sarin; Scopolamine; Serial Learning; Soman

2003
Cognitive side effects in rats caused by pharmacological agents used to prevent soman-induced lethality.
    European journal of pharmacology, 2004, Jan-12, Volume: 483, Issue:2-3

    Topics: Animals; Cognition Disorders; Drug Therapy, Combination; Exploratory Behavior; Lethal Dose 50; Male; Physostigmine; Procyclidine; Rats; Rats, Wistar; Scopolamine; Soman

2004
Protection against soman-induced seizures in rats: relationship among doses of prophylactics, soman, and adjuncts.
    Toxicology and applied pharmacology, 2004, May-01, Volume: 196, Issue:3

    Topics: Animals; Cholinesterase Inhibitors; Convulsants; Dizocilpine Maleate; Dose-Response Relationship, Drug; Electroencephalography; Hippocampus; Male; Muscarinic Antagonists; Neuroprotective Agents; Physostigmine; Procyclidine; Rats; Rats, Wistar; Scopolamine; Seizures; Soman

2004
Stress adversely affects efficacy of physostigmine-scopolamine pretreatment against soman in guinea pigs.
    Pharmacology, biochemistry, and behavior, 2005, Volume: 82, Issue:1

    Topics: Animals; Chemical Warfare Agents; Drug Combinations; Electroencephalography; Guinea Pigs; Physostigmine; Reflex, Startle; Scopolamine; Soman; Stress, Physiological

2005
Nicotinic mechanisms contribute to soman-induced symptoms and lethality.
    Neurotoxicology, 2006, Volume: 27, Issue:4

    Topics: Acetylcholinesterase; Analysis of Variance; Animals; Behavior, Animal; Chemical Warfare Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Female; Hyperkinesis; Lethal Dose 50; Mecamylamine; Mice; Muscarinic Antagonists; Muscle Rigidity; Nicotine; Nicotinic Antagonists; Poisoning; Scopolamine; Soman; Time Factors; Tremor

2006
Roles of perirhinal and posterior piriform cortices in control and generation of seizures: a microinfusion study in rats exposed to soman.
    Neurotoxicology, 2010, Volume: 31, Issue:1

    Topics: Animals; Anticonvulsants; Cerebral Cortex; Disease Models, Animal; Electroencephalography; GABA Agonists; Male; Muscarinic Antagonists; Muscimol; Procyclidine; Quinoxalines; Rats; Rats, Wistar; Scopolamine; Seizures; Soman; Statistics, Nonparametric

2010
Protective effects of aerosolized scopolamine against soman-induced acute respiratory toxicity in guinea pigs.
    International journal of toxicology, 2011, Volume: 30, Issue:6

    Topics: Acetylcholinesterase; Aerosols; Animals; Bronchoalveolar Lavage Fluid; Butyrylcholinesterase; Cell Count; Chemical Warfare Agents; Guinea Pigs; Lung; Male; Muscarinic Antagonists; Protective Agents; Respiratory Function Tests; Scopolamine; Soman; Trachea

2011
Neuropharmacological specificity of brain structures involved in soman-induced seizures.
    Neurotoxicology, 2012, Volume: 33, Issue:3

    Topics: Animals; Anticonvulsants; Brain; Brain Mapping; Chemical Warfare Agents; Cholinergic Antagonists; Dizocilpine Maleate; Dose-Response Relationship, Drug; Electroencephalography; Excitatory Amino Acid Antagonists; Male; Midazolam; Rats; Rats, Sprague-Dawley; Scopolamine; Seizures; Soman

2012
Determination of anti-convulsant and life-preserving capacities of three types of auto-injector therapies against soman intoxication in rats.
    Drug testing and analysis, 2013, Volume: 5, Issue:8

    Topics: Animals; Antidotes; Atropine; Benzodiazepines; Cholinesterase Inhibitors; Convulsants; Male; Oximes; Physostigmine; Rats; Rats, Wistar; Scopolamine; Seizures; Soman

2013
Anticonvulsant effectiveness of scopolamine against soman-induced seizures in African green monkeys.
    Drug and chemical toxicology, 2022, Volume: 45, Issue:5

    Topics: Animals; Anticonvulsants; Chlorocebus aethiops; Cholinesterase Inhibitors; Electroencephalography; Guinea Pigs; Male; Nerve Agents; Rats; Scopolamine; Seizures; Soman

2022