soman has been researched along with obidoxime chloride in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (25.81) | 18.7374 |
| 1990's | 13 (41.94) | 18.2507 |
| 2000's | 7 (22.58) | 29.6817 |
| 2010's | 3 (9.68) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bajgar, J; Fusek, J; Jakl, A; Patocka, J | 1 |
| Goulet, JC; Hand, BT; Lundy, PM | 1 |
| Clement, JG; Gennings, C; Shiloff, JD | 1 |
| Artursson, E; Bucht, G; Puu, G | 1 |
| Okonek, S | 1 |
| Schoene, K | 1 |
| Inns, RH; Leadbeater, L | 1 |
| De Bisschop, HC; Nicaise, M; Willems, JL | 1 |
| Kassa, J | 3 |
| Clement, JG; Erhardt, N | 1 |
| Clement, JG | 1 |
| Aas, P; Fonnum, F; Haider, T; Walday, P | 1 |
| Bajgar, J; Kassa, J | 3 |
| Aas, P | 1 |
| Knopff, O; Szinicz, L; Widmann, R; Worek, F | 1 |
| Kassa, J; Koupilová, M | 2 |
| Eyer, P; Kiderlen, D; Klimmek, R; Worek, F | 1 |
| HEILBRONN, E; TOLAGEN, B | 1 |
| Aas, P; Tansø, R; Øydvin, OK | 1 |
| Reiner, E; Simeon-Rudolf, V | 1 |
| Bajgar, J; Jun, D; Kuca, K | 1 |
| Karasova, J; Kassa, J | 1 |
| Joosen, MJ; Smit, AB; van Helden, HP | 1 |
| Baati, R; Gillon, E; Jean, L; Mercey, G; Nachon, F; Renard, PY; Saint-André, G; Verdelet, T; Wagner, A | 1 |
| Antonijević, B; Bokonjić, D; Stojiljković, MP; Vucinić, S | 1 |
| Agnusdei, M; Belinskaya, T; Borriello, M; Brindisi, M; Butini, S; Campiani, G; Catalanotti, B; Fattorusso, C; Fiorini, I; Gemma, S; Nacci, V; Novellino, E; Panico, A; Persico, M; Ros, S; Saxena, A | 1 |
31 other study(ies) available for soman and obidoxime chloride
| Article | Year |
|---|---|
Efficacy of various pretreatment and therapy regimens against soman lethality in mice.
Topics: Animals; Atropine; Diazepam; Female; Male; Mice; Obidoxime Chloride; Poisoning; Pyridostigmine Bromide; Soman; Trihexyphenidyl; Trimedoxime | 1991 |
Hormone- and dose schedule-dependent protection by HI-6 against soman and tabun poisoning.
Topics: Animals; Body Weight; Cholinesterase Inhibitors; Cholinesterase Reactivators; Female; Guinea Pigs; Lethal Dose 50; Male; Obidoxime Chloride; Orchiectomy; Organophosphates; Organophosphorus Compounds; Ovariectomy; Oximes; Pyridinium Compounds; Rats; Rats, Inbred Strains; Soman; Species Specificity; Testosterone; Time Factors | 1989 |
Efficacy of a combination of acetylcholinesterase reactivators, HI-6 and obidoxime, against tabun and soman poisoning of mice.
Topics: Acetylcholinesterase; Animals; Cholinesterase Inhibitors; Cholinesterase Reactivators; Drug Therapy, Combination; Male; Mice; Obidoxime Chloride; Organophosphate Poisoning; Organophosphates; Oximes; Pyridinium Compounds; Soman | 1987 |
Reactivation of nerve agent inhibited human acetylcholinesterases by HI-6 and obidoxime.
Topics: Acetylcholinesterase; Caudate Nucleus; Cholinesterase Reactivators; Edrophonium; Humans; Muscles; Obidoxime Chloride; Organophosphates; Organothiophosphorus Compounds; Oximes; Pyridinium Compounds; Sarin; Soman; Stereoisomerism | 1986 |
[Gaschromatographic studies on direct reaction of soman and paraoxon with Pyridinium aldoximes in vitro].
Topics: Antidotes; Blood; Chemical Phenomena; Chemistry; Cholinesterase Reactivators; Chromatography, Gas; Humans; Hydrolysis; Insecticides; Kinetics; Nitrophenols; Obidoxime Chloride; Oximes; Paraoxon; Poisoning; Pyridinium Compounds; Soman; Time Factors | 1972 |
[Phosphonyloxime of soman; formation and reaction with acetylcholinesterase in vitro].
Topics: Animals; Cattle; Chemical Phenomena; Chemistry; Cholinesterase Inhibitors; Erythrocytes; In Vitro Techniques; Male; Obidoxime Chloride; Organophosphorus Compounds; Oximes; Pyridinium Compounds; Soman; Stereoisomerism | 1973 |
The efficacy of bispyridinium derivatives in the treatment of organophosphonate poisoning in the guinea-pig.
Topics: Animals; Atropine; Diazepam; Female; Guinea Pigs; Obidoxime Chloride; Organophosphate Poisoning; Pyridinium Compounds; Pyridostigmine Bromide; Soman | 1983 |
Delayed neuropathy by the organophosphorus nerve agents soman and tabun.
Topics: Animals; Chickens; Cholinesterase Inhibitors; Cholinesterase Reactivators; Female; Lethal Dose 50; Obidoxime Chloride; Organophosphates; Organophosphorus Compounds; Oximes; Peripheral Nervous System Diseases; Pyridinium Compounds; Soman | 1984 |
Comparison of efficacy of two oximes (HI-6 and obidoxime) in soman poisoning in rats.
Topics: Acetylcholinesterase; Animals; Antidotes; Brain; Cholinesterase Reactivators; Cortisone; Female; Liver; Obidoxime Chloride; Oximes; Poisoning; Pyridinium Compounds; Rats; Rats, Wistar; Soman; Tyrosine Transaminase | 1995 |
In vitro oxime-induced reactivation of various molecular forms of soman-inhibited acetylcholinesterase in striated muscle from rat, monkey and human.
Topics: Acetylcholinesterase; Analysis of Variance; Animals; Antidotes; Cholinesterase Inhibitors; Cholinesterase Reactivators; Female; Humans; In Vitro Techniques; Macaca fascicularis; Male; Muscle, Skeletal; Obidoxime Chloride; Oximes; Pyridinium Compounds; Rats; Rats, Sprague-Dawley; Soman; Species Specificity; Tissue Preservation | 1994 |
Pharmacological nature of soman-induced hypothermia in mice.
Topics: Acetylcholinesterase; Animals; Atropine; Body Temperature; Cholinesterase Inhibitors; Cholinesterase Reactivators; Hypothalamus; Hypothermia; Male; Mecamylamine; Mice; Nicotine; Obidoxime Chloride; Oximes; Oxotremorine; Physostigmine; Pyridinium Compounds; Soman | 1993 |
Effect of pyridostigmine pretreatment, HI-6 and Toxogonin treatment on rat tracheal smooth muscle response to cholinergic stimulation after organophosphorus inhalation exposure.
Topics: Administration, Inhalation; Animals; Cholinesterase Inhibitors; Cholinesterase Reactivators; Electric Stimulation; Male; Muscle Contraction; Muscle, Smooth; Obidoxime Chloride; Organophosphorus Compounds; Oximes; Pyridinium Compounds; Pyridostigmine Bromide; Rats; Rats, Wistar; Soman; Trachea | 1993 |
The influence of pharmacological pretreatment on efficacy of HI-6 oxime in combination with benactyzine in soman poisoning in rats.
Topics: Animals; Antidotes; Benactyzine; Brain; Cholinesterase Inhibitors; Cholinesterase Reactivators; Cholinesterases; Corticosterone; Diaphragm; Drug Therapy, Combination; Liver; Male; Muscarinic Antagonists; Obidoxime Chloride; Oximes; Poisoning; Pyridinium Compounds; Pyridostigmine Bromide; Rats; Rats, Wistar; Soman; Trihexyphenidyl; Tyrosine Transaminase | 1996 |
In vitro effects of toxogonin, HI-6 and HLö-7 on the release of [3H]acetylcholine from peripheral cholinergic nerves in rat airway smooth muscle.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Bronchi; Butyrylcholinesterase; Calcium Channel Blockers; Cholinesterase Inhibitors; Cholinesterase Reactivators; Enzyme Activation; Male; Muscle, Smooth; Obidoxime Chloride; Oximes; Parasympathetic Nervous System; Peripheral Nerves; Protein Kinase Inhibitors; Protein Kinases; Pyridines; Pyridinium Compounds; Rats; Rats, Wistar; Soman | 1996 |
Therapeutic efficacy of obidoxime or HI-6 with atropine against intoxication with some nerve agents in mice.
Topics: Animals; Antidotes; Chemical Warfare Agents; Cholinesterase Reactivators; Female; Gas Poisoning; Mice; Obidoxime Chloride; Organophosphate Poisoning; Organophosphorus Compounds; Oximes; Pyridinium Compounds; Sarin; Soman | 1996 |
Reactivating potency of obidoxime, pralidoxime, HI 6 and HLö 7 in human erythrocyte acetylcholinesterase inhibited by highly toxic organophosphorus compounds.
Topics: Acetylcholinesterase; Antidotes; Cholinesterase Inhibitors; Cholinesterase Reactivators; Erythrocytes; Humans; Obidoxime Chloride; Organophosphates; Oximes; Pralidoxime Compounds; Pyridines; Pyridinium Compounds; Soman | 1998 |
A comparison of the efficacy of new asymmetric bispyridinium oxime BI-6 with other oximes (obidoxime, HI-6) against soman in rats.
Topics: Acetylcholinesterase; Animals; Antidotes; Atropine; Brain; Cholinesterase Reactivators; Cholinesterases; Diaphragm; Drug Therapy, Combination; Liver; Male; Obidoxime Chloride; Oximes; Poisoning; Pyridines; Pyridinium Compounds; Rats; Rats, Wistar; Soman; Tyrosine Transaminase | 1998 |
[Comparison of the effects of BI-6, a new asymmetric bipyridine oxime, with HI-6 oxime and obidoxime in combination with atropine on soman and fosdrine toxicity in mice].
Topics: Animals; Atropine; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Insecticides; Male; Mevinphos; Mice; Mice, Inbred Strains; Obidoxime Chloride; Oximes; Pyridinium Compounds; Soman | 1999 |
[Comparison of the reactivating effect of BI-6, a new asymmetrical bispyridinium oxime, with oxime HI-6 and obidoxime on soman-inhibited acetylcholinesterase in the diaphragm and various parts of the brain in rats].
Topics: Acetylcholinesterase; Animals; Antidotes; Brain; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Diaphragm; Male; Obidoxime Chloride; Oximes; Pyridinium Compounds; Rats; Rats, Wistar; Soman | 1999 |
Neuroprotective effects of antidotes in soman-poisoned rats.
Topics: Animals; Antidotes; Atropine; Chemical Warfare Agents; Cholinesterase Inhibitors; Male; Nervous System; Obidoxime Chloride; Poisoning; Rats; Rats, Wistar; Soman | 1999 |
The phosphoryl oxime-destroying activity of human plasma.
Topics: Animals; Aryldialkylphosphatase; Blood Proteins; Carboxylic Ester Hydrolases; Cholinesterase Inhibitors; Cholinesterase Reactivators; Cholinesterases; Erythrocytes; Esterases; Humans; Hydrolases; In Vitro Techniques; Kinetics; Obidoxime Chloride; Rabbits; Soman; Substrate Specificity; Ultrafiltration | 2000 |
Neuroprotective effects of currently used antidotes in soman-poisoned rats.
Topics: Animals; Antidotes; Atropine; Cholinesterase Inhibitors; Cholinesterase Reactivators; Male; Motor Activity; Muscarinic Antagonists; Neuroprotective Agents; Obidoxime Chloride; Rats; Rats, Wistar; Soman | 2000 |
TOXOGONIN IN SARIN, SOMAN AND TABUN POISONING.
Topics: Acetylcholinesterase; Animals; Antidotes; Atropine; Cholinesterase Inhibitors; Cholinesterases; Erythrocytes; Mice; Obidoxime Chloride; Organophosphates; Oximes; Pharmacology; Phosphates; Research; Sarin; Soman; Toxicology | 1965 |
Pre-junctional effects of oximes on [3H]-acetylcholine release in rat hippocampal slices during soman intoxication.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Cholinesterase Inhibitors; Cholinesterase Reactivators; Dose-Response Relationship, Drug; Hippocampus; In Vitro Techniques; Male; Neuromuscular Junction; Obidoxime Chloride; Oximes; Potassium; Pralidoxime Compounds; Pyridines; Pyridinium Compounds; Rats; Rats, Wistar; Soman; Tritium | 2005 |
Pyridinium, imidazolium and quinuclidinium compounds: toxicity and antidotal effects against the nerve agents Tabun and Soman.
Topics: Animals; Antidotes; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Mice; Obidoxime Chloride; Organophosphates; Oximes; Pralidoxime Compounds; Pyridinium Compounds; Rats; Soman; Trimedoxime | 2006 |
Currently used cholinesterase reactivators against nerve agent intoxication: comparison of their effectivity in vitro.
Topics: Animals; Brain; Chemical Warfare Agents; Chlorpyrifos; Cholinesterase Inhibitors; Cholinesterase Reactivators; Dose-Response Relationship, Drug; Obidoxime Chloride; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds; Oximes; Pralidoxime Compounds; Pyridinium Compounds; Rats; Rats, Wistar; Sarin; Soman; Tissue Extracts; Trimedoxime | 2007 |
A comparison of the potency of newly developed oximes (K074, K075) and currently available oximes (obidoxime, HI-6) to counteract soman-induced neurotoxicity in rats.
Topics: Animals; Antidotes; Atropine; Autonomic Nervous System; Behavior, Animal; Butanes; Chemical Warfare Agents; Cholinesterase Reactivators; Drug Therapy, Combination; Male; Motor Activity; Neuroprotective Agents; Neurotoxicity Syndromes; Obidoxime Chloride; Oximes; Pyridinium Compounds; Rats; Rats, Wistar; Soman; Structure-Activity Relationship | 2007 |
Treatment efficacy in a soman-poisoned guinea pig model: added value of physostigmine?
Topics: Animals; Atropine; Brain; Carbamates; Chemical Warfare Agents; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Electroencephalography; Guinea Pigs; Male; Models, Animal; Obidoxime Chloride; Parasympatholytics; Physostigmine; Seizures; Soman; Time Factors; Treatment Outcome | 2011 |
First efficient uncharged reactivators for the dephosphylation of poisoned human acetylcholinesterase.
Topics: Acetylcholinesterase; Cholinesterase Inhibitors; Erythrocytes; Humans; Molecular Structure; Obidoxime Chloride; Organophosphates; Organophosphorus Compounds; Oximes; Pyridines; Pyridinium Compounds; Soman | 2011 |
[Antidotal effect of combinations obidoxime/HI-6 and memantine in mice poisoned with soman, dichlorvos or heptenophos].
Topics: Animals; Antidotes; Cholinesterase Reactivators; Dichlorvos; Drug Therapy, Combination; Male; Memantine; Mice; Obidoxime Chloride; Organophosphate Poisoning; Organophosphorus Compounds; Oximes; Pyridinium Compounds; Soman | 2011 |
Exploiting protein fluctuations at the active-site gorge of human cholinesterases: further optimization of the design strategy to develop extremely potent inhibitors.
Topics: Acetylcholinesterase; Binding Sites; Butyrylcholinesterase; Cholinesterase Inhibitors; Computational Biology; Crystallography, X-Ray; Drug Design; Humans; Models, Molecular; Protein Conformation; Structure-Activity Relationship; Tacrine | 2008 |