Page last updated: 2024-08-18

soman and isoflurophate

soman has been researched along with isoflurophate in 78 studies

Research

Studies (78)

Timeframe	Studies, this research(%)	All Research%
pre-1990	41 (52.56)	18.7374
1990's	22 (28.21)	18.2507
2000's	7 (8.97)	29.6817
2010's	5 (6.41)	24.3611
2020's	3 (3.85)	2.80

Authors

Authors	Studies
Agnusdei, M; Belinskaya, T; Borriello, M; Brindisi, M; Butini, S; Campiani, G; Catalanotti, B; Fattorusso, C; Fiorini, I; Gemma, S; Nacci, V; Novellino, E; Panico, A; Persico, M; Ros, S; Saxena, A	1
Harris, LW; Heyl, WC; Moore, RD; Stitcher, DL	1
Koning, LJ; van der Meer, C	1
Gay, DD; Hoskin, FC	1
Lanks, KW; Lieske, CN; Papirmeister, B	1
Alkalai, D; Cohen, G; Kadar, T; Sahar, R; Shapira, S	1
Das Gupta, S; Dube, SN; Jaiswal, DK; Kumar, D; Sikder, AK; Sikder, N	1
Muona, O; Nelson, SR; Pazdernik, TL; Samson, FE; Savolainen, KM	1
Gray, PJ; Michaelson, S	1
Philippens, IH; Vanwersch, RA; Wolthuis, OL	1
Rosenberg, P; Schupper, H	1
Clement, JG	1
Melchers, BP; van Helden, HP	1
Philippens, IH; Vanwersch, R; Wolthuis, OL	1
Gross, CL; Kagey-Sobotka, A; Kilduff, JE; Meier, HL; Papirmeister, B	1
Donlon, MA; Franz, DR; Helgeson, EA; Newball, HH; Procell, LR	1
Gross, CL; Meier, HL; Papirmeister, B	1
Chatonnet, A; Masson, P	1
Dewey, WL; Tripathi, HL	1
Forster, JS; Hammond, PS	1
Chettur, G; DeFrank, JJ; Gallo, BJ; Hoskin, FC; Mainer, S; Robbins, FM; Steinmann, KE; Walker, JE	1
Anderson, RS; Durst, HD; Landis, WG	1
Boucher, LJ; Broomfield, CA; Fox-Talbot, MK; Lenz, DE; Little, JS; MacIver, B	1
Benschop, HP; De Bisschop, HC; Johnson, MK; Read, DJ; Willems, JL	2
Clinton, ME; Dettbarn, WD; Misulis, KE	1
Haraldsson, S; Lundberg, S; Marchner, H	1
Churchill, L; Cross, RS; Giesler, MP; Nelson, SR; Pazdernik, TL; Samson, FE	1
Dettbarn, WD; Gupta, RC; Patterson, GT	1
Andersen, RA; Fonnum, F; Malthe-Sørenssen, D; Odden, E	1
Dettbarn, WD; Gupta, RC	1
Clinton, ME; Dettbarn, WD; Gupta, RC; Misulis, KE	1
Anderson, RJ	1
Lynch, MR; Rice, MA; Robinson, SE	1
Haley, MV; Johnson, DW; Landis, WG	1
Flynn, CJ; Wecker, L	1
Bonds, AB; DeBruyn, EJ; Gajewski, YA	1
Anderson, RJ; Dunham, CB	1
Goasdoue, JL; Masson, P	1
Hoskin, FC	1
Brezenoff, HE; Hymowitz, N; McGee, J	1
Hoskin, FC; Landis, WG; Savage, RE	1
Lebeda, FJ; Rutecki, PA	1
Barney, BA; Lenz, DE	1
Ellenberger, T; Sikora-VanMeter, KC; VanMeter, WG	1
Bachelard, HS; Clark, AG; Jović, R; Nicholas, PC	1
Heath, C; Preston, E	1
Hoskin, FC; Prusch, RD	1
Hoskin, FC; Kirkish, MA; Steinmann, KE	1
Ho, IK; Hoskins, B; Sivam, SP	1
Hoskin, FC; Roush, AH	1
MacGlashan, DW; Meier, HL; Warner, J	1
Aslanian, D; Gróf, P; Masson, P; Renault, F	1
Dettbarn, WD; Hoskin, FC; Walker, JE; Wild, JR	1
Hoskin, FC; Steeves, DM; Walker, JE; Woodbury, CT	1
Ariel, N; Barak, D; Kronman, C; Marcus, D; Ordentlich, A; Shafferman, A; Stein, D; Velan, B	1
Ariel, N; Ashani, Y; Barak, D; Doctor, BP; Grunwald, J; Segall, Y; Waysbort, D	1
Hänninen, O; Kaliste-Korhonen, E; Raushel, FM; Tuovinen, K	1
Degenhardt-Langelaan, CE; Kientz, CE	1
Hoskin, FC; Walker, JE	1
Barak, D; Greenblatt, HM; Harel, M; Kryger, G; Millard, CB; Ordentlich, A; Raves, ML; Segall, Y; Shafferman, A; Silman, I; Sussman, JL	1
Albaret, C; Cléry, C; Fortier, PL; Guerra, P; Lockridge, O; Masson, P	1
Hoskin, FC; Mello, CM; Walker, JE	1
Maxwell, DM; Sweeney, RE	1
Popov, BN; Xie, Y	1
Barcza, T; Cheng, TC; DeFrank, JJ; Hong, K; Jaing, J; Jaszberenyi, JC; Madec, J; McGuinn, WD; Papahadjopoulos, D; Pei, L; Petrikovics, I; Song, ZH; Sylvester, D; Tamulinas, C; Way, JL; Yin, R	1
Le Guével, E; Moutiers, G; Rodriguez-Dafonte, P; Terrier, F	1
Froment, MT; Li, H; Lockridge, O; Masson, P; Nachon, F; Schopfer, LM	1
Grigoryan, H; Lockridge, O; Masson, P; Schopfer, LM; Terry, AV; Thompson, CM	1
Asojo, O; Carlson, JE; Carr, J; Ding, SJ; Hinrichs, SH; Li, B; Li, Y; Lockridge, O; Masson, P; Nachon, F; Schopfer, LM; Thompson, CM; Tong, L; Xue, W	1
Campbell, AJ; Clarkson, ED; Demar, JC; Evans, SA; Gordon, RK; Herdman, CA; Khan, FA; Ku, TC; Leader, H; Marek, E; Medynets, MA; Nambiar, MP; Owens, RR; Ratcliffe, RH; Schulz, SM; Thangavelu, SG	1
Meyerhoff, ME; Meyeroff, ME; Ramanathan, M; Simonian, AL; Wang, L; Wild, JR	1
Costero, AM; Gil, S; Gotor, R; Martínez-Máñez, R; Parra, M; Sancenón, F	1
Gor, GY; Lee, MT; Neimark, AV; Vishnyakov, A	1
Anslyn, EV; Phillips, ST; Reuther, JF; Sun, X	1
Bouknight, KD; Compton, JR; Guelta, MA; Harvey, SP; Jurkouich, KM; Khavrutskii, IV; Legler, PM	1
Abreu-Melon, J; Dingledine, R; McCarren, HS; McDonough, JH; Rojas, A; Wang, J; Wang, S; Wang, W	1
Kuruba, R; Reddy, DS; Wu, X; Zaayman, M	1

Other Studies

78 other study(ies) available for soman and isoflurophate

Article	Year
Exploiting protein fluctuations at the active-site gorge of human cholinesterases: further optimization of the design strategy to develop extremely potent inhibitors. Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Acetylcholinesterase; Binding Sites; Butyrylcholinesterase; Cholinesterase Inhibitors; Computational Biology; Crystallography, X-Ray; Drug Design; Humans; Models, Molecular; Protein Conformation; Structure-Activity Relationship; Tacrine	2008
Synthesis of cholinesterase following poisoning with irreversible anticholinesterases: effects of theophylline and N6,O2-dibutyryl adenosine 3',5'-monophosphate on synthesis and survival. Toxicology and applied pharmacology, 1977, Volume: 41, Issue:1 Topics: Acetylcholinesterase; Animals; Brain; Bucladesine; Butyrylcholinesterase; Cholinesterase Inhibitors; Cholinesterases; Drug Interactions; Female; Isoflurophate; Lethal Dose 50; Liver; Male; Mice; Muscles; Protein Biosynthesis; Rats; Soman; Theophylline; Time Factors	1977
The cause of death of Palaemonetes varians (Leach, 1814) treated with cholinesterase inhibitors. Comparative biochemistry and physiology. C: Comparative pharmacology, 1975, Jun-01, Volume: 51, Issue:1 Topics: Animals; Crustacea; Death; Dose-Response Relationship, Drug; Heart; Heart Arrest; Heart Rate; Isoflurophate; Organophosphorus Compounds; Paraoxon; Parathion; Soman; Time Factors	1975
Stereospecificity and active site requirements in a diisopropylphosphorofluoridate-hydrolyzing enzyme. Biochemical pharmacology, 1979, Apr-01, Volume: 28, Issue:7 Topics: Animals; Binding Sites; Decapodiformes; Isoflurophate; Kinetics; Molecular Conformation; Optical Rotation; Organophosphorus Compounds; Soman; Substrate Specificity	1979
Spontaneous reactivation of acetylcholinesterase following organophosphate inhibition. II. Characterization of the reactivating components. Biochimica et biophysica acta, 1977, Aug-11, Volume: 483, Issue:2 Topics: Acetylcholinesterase; Animals; Electrophorus; Enzyme Activation; Isoflurophate; Kinetics; Molecular Weight; Organophosphorus Compounds; Phenylacetates; Sarin; Soman	1977
Long-term study of brain lesions following soman, in comparison to DFP and metrazol poisoning. Human & experimental toxicology, 1992, Volume: 11, Issue:6 Topics: Animals; Brain; Isoflurophate; Lethal Dose 50; Male; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Soman	1992
Therapeutic efficacy of bis-pyridinium oximes against diisopropyl fluorophosphate (DFP) and soman intoxication in rodents. Die Pharmazie, 1992, Volume: 47, Issue:1 Topics: Animals; Cholinesterase Reactivators; Isoflurophate; Mice; Neuromuscular Blocking Agents; Oximes; Phrenic Nerve; Poisoning; Pyridinium Compounds; Rats; Respiratory Muscles; Soman	1992
Lithium modifies convulsions and brain phosphoinositide turnover induced by organophosphates. Pharmacology & toxicology, 1991, Volume: 68, Issue:5 Topics: Animals; Brain; Chlorides; Chromatography, Gas; Drug Synergism; Inositol Phosphates; Insecticides; Isoflurophate; Lithium; Lithium Chloride; Male; Paraoxon; Rats; Rats, Inbred Strains; Seizures; Soman	1991
A second site of action of soman on acetylcholinesterase. Biochemical pharmacology, 1991, Oct-24, Volume: 42, Issue:10 Topics: Acetylcholinesterase; Binding Sites; Cholinesterase Inhibitors; Isoflurophate; Soman	1991
On the development of behavioral tolerance to organophosphates. IV: EEGand visual evoked responses. Pharmacology, biochemistry, and behavior, 1991, Volume: 39, Issue:4 Topics: Animals; Behavior, Animal; Body Temperature; Conditioning, Operant; Drug Tolerance; Electroencephalography; Electroshock; Evoked Potentials, Visual; Isoflurophate; Male; Organophosphorus Compounds; Pupil; Rats; Rats, Inbred Strains; Soman	1991
Effects of diisopropyl phosphofluoridate, sarin and soman on the accessibility of proteins, in the electroplax membrane, to lactoperoxidase-catalyzed iodination. Biochemical pharmacology, 1991, Sep-12, Volume: 42, Issue:7 Topics: Animals; Cell Membrane Permeability; Cholinesterases; Electrophoresis, Polyacrylamide Gel; Electrophorus; In Vitro Techniques; Iodine Radioisotopes; Isoflurophate; Lactoperoxidase; Lipid Bilayers; Macromolecular Substances; Membrane Proteins; Molecular Weight; Proteins; Sarin; Soman	1991
Hypothermia: limited tolerance to repeated soman administration and cross-tolerance to oxotremorine. Pharmacology, biochemistry, and behavior, 1991, Volume: 39, Issue:2 Topics: Acetylcholinesterase; Animals; Body Temperature; Carboxylic Ester Hydrolases; Dose-Response Relationship, Drug; Drug Tolerance; Isoflurophate; Liver; Male; Mice; Mixed Function Oxygenases; Oxotremorine; Soman	1991
On the development of behavioral tolerance to organophosphates. II: Neurophysiological aspects. Pharmacology, biochemistry, and behavior, 1990, Volume: 35, Issue:2 Topics: Acetylcholinesterase; Animals; Drug Tolerance; Electrophysiology; Isoflurophate; Male; Neuromuscular Junction; Random Allocation; Rats; Rats, Inbred Strains; Soman; Synaptic Transmission	1990
On the development of behavioral tolerance to organophosphates. III: Behavioral aspects. Pharmacology, biochemistry, and behavior, 1990, Volume: 35, Issue:3 Topics: Animals; Behavior, Animal; Cholinesterases; Dose-Response Relationship, Drug; Drug Tolerance; Enzyme Inhibitors; Isoflurophate; Male; Organophosphorus Compounds; Rats; Rats, Inbred Strains; Soman	1990
Histamine release by esterase inhibitors. The regulation of histamine release from human leukocytes of allergic and non-allergic individuals by the serine esterase inhibitors diisopropyl fluorophosphate and pinacolyl methylphosphorofluoridate. International archives of allergy and applied immunology, 1985, Volume: 77, Issue:1-2 Topics: Enzyme Inhibitors; Esterases; Histamine Release; Humans; Hypersensitivity; Isoflurophate; Kinetics; Organophosphorus Compounds; Physostigmine; Pyridostigmine Bromide; Soman; Temperature	1985
Organophosphate-induced histamine release from mast cells. The Journal of pharmacology and experimental therapeutics, 1986, Volume: 238, Issue:3 Topics: Animals; Calcium; Cromolyn Sodium; Dose-Response Relationship, Drug; Energy Metabolism; Histamine Release; In Vitro Techniques; Isoflurophate; Kinetics; Mast Cells; p-Methoxy-N-methylphenethylamine; Rats; Soman; Temperature	1986
Regulation by serine esterase of histamine release from human leukocytes--I. Direct release of histamine by the serine esterase inhibitors diisopropyl fluorophosphate (DFP) and soman (GD). Biochemical pharmacology, 1986, Dec-01, Volume: 35, Issue:23 Topics: Edetic Acid; Esterases; Histamine Release; Humans; Immunoglobulin E; In Vitro Techniques; Isoflurophate; Kinetics; Leukocytes; NAD; Soman	1986
Study of the peptidasic site of cholinesterase: preliminary results. FEBS letters, 1985, Mar-25, Volume: 182, Issue:2 Topics: Binding Sites; Butyrylcholinesterase; Cholinesterase Inhibitors; Cholinesterases; Diethyl Pyrocarbonate; Histidine; Humans; Isoflurophate; Neuraminidase; Organophosphorus Compounds; Peptide Hydrolases; Quinolines; Serine; Soman; Substance P; Tosyllysine Chloromethyl Ketone	1985
Comparison of the effects of diisopropylfluorophosphate, sarin, soman, and tabun on toxicity and brain acetylcholinesterase activity in mice. Journal of toxicology and environmental health, 1989, Volume: 26, Issue:4 Topics: Acetylcholinesterase; Animals; Brain; Cholinesterase Inhibitors; Isoflurophate; Lethal Dose 50; Male; Mice; Mice, Inbred ICR; Organophosphates; Organophosphorus Compounds; Sarin; Soman	1989
A microassay-based procedure for measuring low levels of toxic organophosphorus compounds through acetylcholinesterase inhibition. Analytical biochemistry, 1989, Aug-01, Volume: 180, Issue:2 Topics: Acetylcholinesterase; Cholinesterase Inhibitors; Isoflurophate; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds; Paraoxon; Reference Standards; Soman; Spectrophotometry	1989
Soman-hydrolyzing and -detoxifying properties of an enzyme from a thermophilic bacterium. Fundamental and applied toxicology : official journal of the Society of Toxicology, 1988, Volume: 11, Issue:3 Topics: Bacteria; Cholinesterase Inhibitors; Electrodes; Hydrolysis; Inactivation, Metabolic; Isoflurophate; Phosphoric Monoester Hydrolases; Soman	1988
Organofluorophosphate-hydrolyzing activity in an estuarine clam, Rangia cuneata. Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1988, Volume: 91, Issue:2 Topics: Animals; Bivalvia; Digestive System; Esterases; Hydrolases; Hydrolysis; Isoflurophate; Molecular Weight; Phosphoric Triester Hydrolases; Soman	1988
Partial characterization of an enzyme that hydrolyzes sarin, soman, tabun, and diisopropyl phosphorofluoridate (DFP). Biochemical pharmacology, 1989, Jan-01, Volume: 38, Issue:1 Topics: Animals; Hydrolases; Hydrolysis; Isoflurophate; Kinetics; Liver; Magnesium; Male; Organophosphates; Organophosphorus Compounds; Rats; Rats, Inbred Strains; Sarin; Soman; Stereoisomerism	1989
High doses of soman protect against organophosphorus-induced delayed polyneuropathy but tabun does not. Toxicology and applied pharmacology, 1988, Volume: 92, Issue:1 Topics: Animals; Ataxia; Atropine; Carboxylic Ester Hydrolases; Chickens; Diazepam; Drug Interactions; Female; Isoflurophate; Isomerism; Organophosphates; Organophosphorus Compounds; Physostigmine; Soman	1988
Effects of phenytoin, ketamine, and atropine methyl nitrate in preventing neuromuscular toxicity of acetylcholinesterase inhibitors soman and diisopropylphosphorofluoridate. Journal of toxicology and environmental health, 1988, Volume: 24, Issue:4 Topics: Animals; Atropine Derivatives; Cholinesterase Inhibitors; Cholinesterase Reactivators; Isoflurophate; Ketamine; Male; Muscle Contraction; Muscle Denervation; Muscles; Neuromuscular Junction; Phenytoin; Rats; Rats, Inbred Strains; Soman	1988
Organophosphorus anticholinesterases do not mediate analgesia through inhibition of enkephalin degradation. Life sciences, 1986, Apr-07, Volume: 38, Issue:14 Topics: Acetylcholinesterase; Aminopeptidases; Analgesia; Animals; Brain; Cholinesterase Inhibitors; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Endopeptidases; Enkephalin, Leucine; Enkephalins; Isoflurophate; Male; Neprilysin; Organophosphates; Organophosphorus Compounds; Rats; Rats, Inbred Strains; Sarin; Soman; Synaptosomes	1986
Cholinergic systems influence local cerebral glucose use in specific anatomical areas: diisopropyl phosphorofluoridate versus soman. Neuroscience, 1987, Volume: 20, Issue:1 Topics: Animals; Atropine; Benactyzine; Brain; Cholinergic Fibers; Glucose; Isoflurophate; Male; Rats; Rats, Inbred Strains; Soman; Trimedoxime	1987
Biochemical and histochemical alterations following acute soman intoxication in the rat. Toxicology and applied pharmacology, 1987, Mar-15, Volume: 87, Issue:3 Topics: Acetylcholinesterase; Animals; Brain; Butyrylcholinesterase; Carboxylic Ester Hydrolases; Histocytochemistry; Isoflurophate; Male; Muscles; Necrosis; Rats; Rats, Inbred Strains; Soman	1987
Effects of organophosphates on presynaptic events in the vascularly perfused phrenic nerve-hemidiaphragm preparation from the rat. Biochemical pharmacology, 1987, Apr-01, Volume: 36, Issue:7 Topics: Acetylcholine; Animals; Cholinesterase Inhibitors; Diaphragm; Electric Stimulation; Female; In Vitro Techniques; Isoflurophate; Male; Muscles; Organophosphorus Compounds; Organothiophosphorus Compounds; Perfusion; Phrenic Nerve; Rats; Rats, Inbred Strains; Sarin; Soman; Synapses	1987
Alterations of high-energy phosphate compounds in the skeletal muscles of rats intoxicated with diisopropylphosphorofluoridate (DFP) and Soman. Fundamental and applied toxicology : official journal of the Society of Toxicology, 1987, Volume: 8, Issue:3 Topics: Adenine Nucleotides; Animals; Creatine; Drug Tolerance; Isoflurophate; Male; Muscles; Phosphates; Phosphocreatine; Rats; Rats, Inbred Strains; Soman	1987
Differences in central and peripheral neural actions between soman and diisopropyl fluorophosphate, organophosphorus inhibitors of acetylcholinesterase. Toxicology and applied pharmacology, 1987, Volume: 89, Issue:3 Topics: Acetylcholinesterase; Animals; Brain; Central Nervous System; Cholinesterase Inhibitors; Denervation; Electroencephalography; Isoflurophate; Muscles; Peripheral Nerves; Rats; Rats, Inbred Strains; Soman; Spinal Cord	1987
Effect of diisopropylfluorophosphate and soman on rat skeletal muscle contracture during tetanic stimulation. Journal of toxicology and environmental health, 1987, Volume: 22, Issue:4 Topics: Animals; Isoflurophate; Male; Muscle Contraction; Muscles; Rats; Rats, Inbred Strains; Soman	1987
Dissociation of locomotor depression and ChE activity after DFP, soman and sarin. Pharmacology, biochemistry, and behavior, 1986, Volume: 24, Issue:4 Topics: Animals; Brain; Brain Mapping; Cholinergic Fibers; Cholinesterases; Corpus Striatum; Isoflurophate; Male; Motor Activity; Organophosphorus Compounds; Rats; Rats, Inbred Strains; Sarin; Soman	1986
Kinetics of the DFPase activity in Tetrahymena thermophila. The Journal of protozoology, 1986, Volume: 33, Issue:2 Topics: Animals; Esterases; Hydrogen-Ion Concentration; Hydrolases; Isoflurophate; Kinetics; Phosphoric Triester Hydrolases; Soman; Temperature; Tetrahymena	1986
Elevated choline levels in brain. A non-cholinergic component of organophosphate toxicity. Biochemical pharmacology, 1986, Sep-15, Volume: 35, Issue:18 Topics: Acetylcholinesterase; Animals; Brain; Choline; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Isoflurophate; Male; Microwaves; Paraoxon; Rats; Rats, Inbred Strains; Sarin; Soman	1986
Anticholinesterase agents affect contrast gain of the cat cortical visual evoked potential. Neuroscience letters, 1986, Nov-21, Volume: 71, Issue:3 Topics: Acetylcholine; Animals; Atropine; Cats; Cholinesterase Inhibitors; Evoked Potentials, Visual; Isoflurophate; Physostigmine; Pyridostigmine Bromide; Soman; Visual Cortex; Visual Perception	1986
Electrophysiologic changes in peripheral nerve following repeated exposure to organophosphorus agents. Archives of toxicology, 1985, Volume: 58, Issue:2 Topics: Action Potentials; Animals; Behavior, Animal; Electrophysiology; Evoked Potentials; Isoflurophate; Lethal Dose 50; Male; Membrane Potentials; Rats; Rats, Inbred Strains; Sciatic Nerve; Soman	1985
Evidence that the conformational stability of 'aged' organophosphate-inhibited cholinesterase is altered. Biochimica et biophysica acta, 1986, Feb-14, Volume: 869, Issue:3 Topics: Butyrylcholinesterase; Cholinesterase Inhibitors; Cholinesterases; Electrophoresis, Polyacrylamide Gel; Humans; Isoflurophate; Macromolecular Substances; Protein Conformation; Protein Denaturation; Soman; Sulfones; Temperature; Thermodynamics; Urea	1986
Inhibition of a soman- and diisopropyl phosphorofluoridate (DFP)-detoxifying enzyme by Mipafox. Biochemical pharmacology, 1985, Jun-15, Volume: 34, Issue:12 Topics: Animals; Esterases; Humans; Hydrolases; Hydrolysis; Isoflurophate; Organophosphorus Compounds; Phosphoric Triester Hydrolases; Soman	1985
Inhibition of acetylcholinesterase in the gut inhibits schedule-controlled behavior in the rat. Life sciences, 1985, Jul-08, Volume: 37, Issue:1 Topics: Animals; Cholinesterase Inhibitors; Conditioning, Psychological; Digestive System; Injections, Intraperitoneal; Injections, Subcutaneous; Isoflurophate; Male; Neostigmine; Rats; Rats, Inbred Strains; Soman	1985
An organofluorophosphate-hydrolyzing activity in Tetrahymena thermophila. The Journal of protozoology, 1985, Volume: 32, Issue:3 Topics: Animals; Biodegradation, Environmental; Esterases; Hydrolases; Isoflurophate; Phosphoric Triester Hydrolases; Soman; Tetrahymena	1985
Characterization of spontaneous epileptiform discharges induced by organophosphorus anticholinesterases in the in vitro rat hippocampus. Proceedings of the Western Pharmacology Society, 1985, Volume: 28 Topics: Animals; Cholinesterase Inhibitors; Electroencephalography; Epilepsy; Hippocampus; In Vitro Techniques; Insecticides; Isoflurophate; Rats; Rats, Inbred Strains; Soman	1985
The effects of soman, in vivo and in vitro, on aldolase activity. Toxicology letters, 1985, Volume: 28, Issue:2-3 Topics: Animals; Dose-Response Relationship, Drug; Fructose-Bisphosphate Aldolase; In Vitro Techniques; Isoflurophate; Male; Muscles; Rabbits; Rats; Soman	1985
Neurotoxic changes in cat neurohypophysis after single and multiple exposures to diisopropylfluorophosphate and soman. Fundamental and applied toxicology : official journal of the Society of Toxicology, 1985, Volume: 5, Issue:6 Pt 1 Topics: Animals; Axons; Cats; Drug Administration Schedule; Female; Injections, Subcutaneous; Isoflurophate; Lethal Dose 50; Male; Neurons; Pituitary Gland, Posterior; Soman	1985
Can soman cause delayed neuropathy? Fundamental and applied toxicology : official journal of the Society of Toxicology, 1985, Volume: 5, Issue:6 Pt 2 Topics: Animals; Chickens; Esterases; Isoflurophate; Nervous System Diseases; Soman; Stereoisomerism	1985
Effects of soman and DFP in vivo and in vitro on cerebral metabolism in the rat. Biochemical pharmacology, 1971, Volume: 20, Issue:3 Topics: Adenosine Triphosphatases; Animals; Brain; Cholinesterase Inhibitors; Female; Fructose-Bisphosphate Aldolase; Hexokinase; Isoflurophate; Male; Organophosphorus Compounds; Oxygen; Rats; Rats, Inbred Strains; Soman; Succinate Dehydrogenase	1971
Atropine-insensitive vasodilatation and hypotension in the organophosphate-poisoned rabbit. Archives internationales de pharmacodynamie et de therapie, 1972, Volume: 200, Issue:2 Topics: Animals; Atropine; Blood Pressure; Blood Vessels; Cholinesterase Inhibitors; Forelimb; Heart Rate; Hypotension; Isoflurophate; Organophosphate Poisoning; Rabbits; Respiration, Artificial; Sarin; Soman; Vascular Resistance; Vasodilator Agents	1972
Characterization of a DFP-hydrolyzing enzyme in squid posterior salivary gland by use of Soman, DFP and manganous ion. Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1983, Volume: 75, Issue:1 Topics: Animals; Cations, Divalent; Decapodiformes; Esterases; Female; Hydrolases; Isethionic Acid; Isoflurophate; Male; Manganese; Nerve Tissue; Phosphoric Triester Hydrolases; Rats; Saliva; Salivary Glands; Soman	1983
Two enzymes for the detoxication of organophosphorus compounds--sources, similarities, and significance. Fundamental and applied toxicology : official journal of the Society of Toxicology, 1984, Volume: 4, Issue:2 Pt 2 Topics: Animals; Decapodiformes; Electrophorus; Escherichia coli; Esterases; Hydrolases; In Vitro Techniques; Isoflurophate; Kidney; Manganese; Mollusca; Nephropidae; Neurons; Organophosphates; Organophosphorus Compounds; Phosphoric Triester Hydrolases; Proteus vulgaris; Saccharomyces cerevisiae; Soman; Swine; Tetrahymena	1984
An assessment of comparative acute toxicity of diisopropyl-fluorophosphate, tabun, sarin, and soman in relation to cholinergic and GABAergic enzyme activities in rats. Fundamental and applied toxicology : official journal of the Society of Toxicology, 1984, Volume: 4, Issue:4 Topics: 4-Aminobutyrate Transaminase; Animals; Choline O-Acetyltransferase; Cholinesterase Inhibitors; Corpus Striatum; Erythrocytes; gamma-Aminobutyric Acid; In Vitro Techniques; Isoflurophate; Lethal Dose 50; Male; Organophosphates; Organophosphorus Compounds; Parasympathetic Nervous System; Rats; Rats, Inbred Strains; Sarin; Soman	1984
Hydrolysis of nerve gas by squid-type diisopropyl phosphorofluoridate hydrolyzing enzyme on agarose resin. Science (New York, N.Y.), 1982, Mar-05, Volume: 215, Issue:4537 Topics: Animals; Decapodiformes; Enzymes, Immobilized; Isoflurophate; Kinetics; Molecular Weight; Organophosphorus Compounds; Soman; Stereoisomerism; Substrate Specificity	1982
Simultaneous initiation of degranulation and inhibition of leukotriene release by soman in human basophils. International journal of immunopharmacology, 1995, Volume: 17, Issue:4 Topics: Basophil Degranulation Test; Basophils; Edetic Acid; Histamine Antagonists; Histamine Release; Humans; Immunoglobulin E; Isoflurophate; Leukotriene C4; Leukotriene D4; Leukotriene E4; Signal Transduction; Soman	1995
Raman spectroscopic study of conjugates of butyrylcholinesterase with organophosphates. Biochimica et biophysica acta, 1995, May-18, Volume: 1249, Issue:1 Topics: Butyrylcholinesterase; Cholinesterase Inhibitors; Isoflurophate; Organophosphorus Compounds; Paraoxon; Protein Structure, Secondary; Soman; Spectrum Analysis, Raman	1995
Hydrolysis of tetriso by an enzyme derived from Pseudomonas diminuta as a model for the detoxication of O-ethyl S-(2-diisopropylaminoethyl) methylphosphonothiolate (VX). Biochemical pharmacology, 1995, Mar-01, Volume: 49, Issue:5 Topics: Aryldialkylphosphatase; Chelating Agents; Cholinesterase Inhibitors; Esterases; Inactivation, Metabolic; Isoflurophate; Organophosphorus Compounds; Organothiophosphorus Compounds; Pseudomonas; Soman	1995
Polyclonal antibody generation in rabbit by administration of an organophosphorus acid anhydrolase (OPAA) from squid. Biochemical pharmacology, 1993, Oct-05, Volume: 46, Issue:7 Topics: Animals; Antibody Specificity; Aryldialkylphosphatase; Decapodiformes; Enzyme-Linked Immunosorbent Assay; Escherichia coli; Esterases; Geobacillus stearothermophilus; Immune Sera; Isoflurophate; Liver; Mathematics; Pancreas; Phosphoric Triester Hydrolases; Rabbits; Soman; Swine	1993
Engineering resistance to 'aging' of phosphylated human acetylcholinesterase. Role of hydrogen bond network in the active center. FEBS letters, 1993, Nov-15, Volume: 334, Issue:2 Topics: Acetylcholinesterase; Amino Acid Sequence; Binding Sites; Cholinesterase Inhibitors; Enzyme Stability; Humans; Hydrogen Bonding; Isoflurophate; Kinetics; Mutagenesis, Site-Directed; Phosphorylation; Point Mutation; Protein Conformation; Protein Engineering; Quinolinium Compounds; Recombinant Proteins; Soman	1993
Direct observation and elucidation of the structures of aged and nonaged phosphorylated cholinesterases by 31P NMR spectroscopy. Biochemistry, 1993, Dec-14, Volume: 32, Issue:49 Topics: Acetylcholinesterase; Alkylation; Binding Sites; Butyrylcholinesterase; Cholinesterase Inhibitors; Cholinesterase Reactivators; Chymotrypsin; Isoflurophate; Magnetic Resonance Spectroscopy; Molecular Structure; Organophosphorus Compounds; Phosphorylation; Protein Denaturation; Soman; Stereoisomerism	1993
Protection of organophosphate-inactivated esterases with phosphotriesterase. Fundamental and applied toxicology : official journal of the Society of Toxicology, 1996, Volume: 31, Issue:2 Topics: Animals; Aryldialkylphosphatase; Biological Availability; Brain; Cholinesterase Inhibitors; Drug Antagonism; Esterases; Isoflurophate; Lung; Male; Mice; Sarin; Soman; Time Factors	1996
Capillary gas chromatographic analysis of nerve agents using large volume injections. Journal of chromatography. A, 1996, Feb-02, Volume: 723, Issue:1 Topics: Chemical Warfare Agents; Cholinesterase Inhibitors; Chromatography, Gas; Hydrogen-Ion Concentration; Isoflurophate; Organophosphorus Compounds; Organothiophosphorus Compounds; Sarin; Soman; Water	1996
A closer look at the natural substrate for a nerve-gas hydrolyzing enzyme in squid nerve. The Biological bulletin, 1998, Volume: 195, Issue:2 Topics: Animals; Aryldialkylphosphatase; Cholinesterase Inhibitors; Decapodiformes; Dipeptides; Escherichia coli; Esterases; Hydrolysis; Isoflurophate; Manganese; Nerve Tissue; Pseudomonas; Soman; Swine	1998
Crystal structures of aged phosphonylated acetylcholinesterase: nerve agent reaction products at the atomic level. Biochemistry, 1999, Jun-01, Volume: 38, Issue:22 Topics: Acetylcholinesterase; Acetylthiocholine; Acylation; Animals; Binding Sites; Butyrylthiocholine; Chemical Warfare Agents; Cholinesterase Inhibitors; Crystallography, X-Ray; Enzyme Activation; Humans; Hydrolysis; Isoflurophate; Kinetics; Models, Molecular; Sarin; Soman; Torpedo	1999
Structural and hydration changes in the active site gorge of phosporhylated butyrylcholinesterase accompanying the aging process. Chemico-biological interactions, 1999, May-14, Volume: 119-120 Topics: Aging; Binding Sites; Butyrylcholinesterase; Cholinesterase Inhibitors; Enzyme Stability; Humans; Hydrogen-Ion Concentration; Hydrostatic Pressure; Isoflurophate; Kinetics; Osmotic Pressure; Phosphorylation; Protein Denaturation; Soman; Structure-Activity Relationship; Thermodynamics	1999
Organophosphorus acid anhydrolase in slime mold, duckweed and mung bean: a continuing search for a physiological role and a natural substrate. Chemico-biological interactions, 1999, May-14, Volume: 119-120 Topics: Animals; Aryldialkylphosphatase; Aspergillus; Chelating Agents; Cholinesterase Inhibitors; Decapodiformes; Dictyostelium; Edetic Acid; Esterases; Fabaceae; Hydrolysis; Inactivation, Metabolic; Isoflurophate; Kinetics; Magnoliopsida; Manganese; Plant Proteins; Plants, Medicinal; Protozoan Proteins; Soman; Tetrahymena thermophila	1999
A theoretical model of the competition between hydrolase and carboxylesterase in protection against organophosphorus poisoning. Mathematical biosciences, 1999, Volume: 160, Issue:2 Topics: Acetylcholinesterase; Animals; Aryldialkylphosphatase; Carboxylic Ester Hydrolases; Cholinesterase Inhibitors; Dichlorvos; Esterases; Isoflurophate; Lethal Dose 50; Models, Biological; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds; Rats; Sarin; Soman	1999
Catalyzed hydrolysis of nerve gases by metal chelate compounds and potentiometric detection of the byproducts. Analytical chemistry, 2000, May-01, Volume: 72, Issue:9 Topics: Catalysis; Chelating Agents; Chemical Warfare Agents; Cholinesterase Inhibitors; Copper; Hydrolysis; Isoflurophate; Potentiometry; Sarin; Soman	2000
Long circulating liposomes encapsulating organophosphorus acid anhydrolase in diisopropylfluorophosphate antagonism. Toxicological sciences : an official journal of the Society of Toxicology, 2000, Volume: 57, Issue:1 Topics: Animals; Aryldialkylphosphatase; Cholinesterase Inhibitors; Drug Carriers; Esterases; Isoflurophate; Lethal Dose 50; Liposomes; Male; Mice; Mice, Inbred BALB C; Sarin; Soman; Substrate Specificity	2000
Revisiting the reactivity of oximate alpha-nucleophiles with electrophilic phosphorus centers. Relevance to detoxification of sarin, soman and DFP under mild conditions. Organic & biomolecular chemistry, 2006, Dec-07, Volume: 4, Issue:23 Topics: Hydrogen-Ion Concentration; Isoflurophate; Kinetics; Organophosphonates; Organophosphorus Compounds; Oximes; Phenols; Sarin; Soman	2006
Aging pathways for organophosphate-inhibited human butyrylcholinesterase, including novel pathways for isomalathion, resolved by mass spectrometry. Toxicological sciences : an official journal of the Society of Toxicology, 2007, Volume: 100, Issue:1 Topics: Butyrylcholinesterase; Catalytic Domain; Chemical Warfare Agents; Cholinesterase Inhibitors; Deuterium Oxide; Dichlorvos; Echothiophate Iodide; Enzyme Stability; Humans; Insecticides; Isoflurophate; Malathion; Molecular Structure; Peptide Mapping; Sarin; Serine; Soman; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Time Factors; Trypsin	2007
Mass spectrometry identifies covalent binding of soman, sarin, chlorpyrifos oxon, diisopropyl fluorophosphate, and FP-biotin to tyrosines on tubulin: a potential mechanism of long term toxicity by organophosphorus agents. Chemico-biological interactions, 2008, Sep-25, Volume: 175, Issue:1-3 Topics: Binding Sites; Biotin; Chlorpyrifos; Cholinesterase Inhibitors; Isoflurophate; Organophosphorus Compounds; Sarin; Soman; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tubulin; Tyrosine	2008
Five tyrosines and two serines in human albumin are labeled by the organophosphorus agent FP-biotin. Chemical research in toxicology, 2008, Volume: 21, Issue:9 Topics: Albumins; Biotin; Chlorpyrifos; Chromatography, Liquid; Crystallography, X-Ray; Dichlorvos; Humans; Hydrogen-Ion Concentration; Isoflurophate; Models, Molecular; Molecular Structure; Organophosphorus Compounds; Reproducibility of Results; Sarin; Serine; Soman; Staining and Labeling; Tandem Mass Spectrometry; Tyrosine	2008
Pro-2-PAM therapy for central and peripheral cholinesterases. Chemico-biological interactions, 2010, Sep-06, Volume: 187, Issue:1-3 Topics: Acetylcholinesterase; Animals; Apoptosis; Brain; Central Nervous System; Cholinesterase Reactivators; Dose-Response Relationship, Drug; Electroencephalography; Enzyme Activation; Guinea Pigs; Hippocampus; Isoflurophate; Male; Neurons; Peripheral Nervous System; Pralidoxime Compounds; Prodrugs; Skin; Soman; Status Epilepticus; Survival Analysis	2010
Monitoring of diisopropyl fluorophosphate hydrolysis by fluoride-selective polymeric films using absorbance spectroscopy. Analytica chimica acta, 2010, May-14, Volume: 667, Issue:1-2 Topics: Absorption; Biocatalysis; Chemical Warfare Agents; Fluorides; Hydrolysis; Isoflurophate; Phosphoric Monoester Hydrolases; Polymers; Sarin; Soman; Spectrophotometry, Ultraviolet	2010
A molecular probe for the highly selective chromogenic detection of DFP, a mimic of Sarin and Soman nerve agents. Chemistry (Weinheim an der Bergstrasse, Germany), 2011, Oct-17, Volume: 17, Issue:43 Topics: Chemical Warfare Agents; Cholinesterase Inhibitors; Chromogenic Compounds; Isoflurophate; Molecular Probes; Molecular Structure; Sarin; Soman	2011
Interactions of phosphororganic agents with water and components of polyelectrolyte membranes. The journal of physical chemistry. B, 2011, Nov-24, Volume: 115, Issue:46 Topics: Electrolytes; Hydrogen Bonding; Isoflurophate; Lipid Bilayers; Models, Chemical; Organophosphorus Compounds; Polystyrenes; Sarin; Solvents; Soman; Thermodynamics; Water	2011
Coupling Activity-Based Detection, Target Amplification, Colorimetric and Fluorometric Signal Amplification, for Quantitative Chemosensing of Fluoride Generated from Nerve Agents. Chemistry (Weinheim an der Bergstrasse, Germany), 2017, Mar-17, Volume: 23, Issue:16 Topics: Colorimetry; Fluorescent Dyes; Fluorides; Isoflurophate; Nerve Agents; Organophosphorus Compounds; Oximes; Phosphates; Sarin; Soman; Spectrometry, Fluorescence	2017
Structural and kinetic evidence of aging after organophosphate inhibition of human Cathepsin A. Biochemical pharmacology, 2020, Volume: 177 Topics: Acetylcholinesterase; Binding Sites; Cathepsin A; Cell Line; Chemical Warfare Agents; Cholinesterase Inhibitors; Crystallography, X-Ray; Gene Expression; GPI-Linked Proteins; HEK293 Cells; Humans; Isoflurophate; Kinetics; Models, Molecular; Organophosphorus Compounds; Organothiophosphorus Compounds; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Recombinant Proteins; Sarin; Soman; Substrate Specificity; Time Factors	2020
Comparison of neuropathology in rats following status epilepticus induced by diisopropylfluorophosphate and soman. Neurotoxicology, 2021, Volume: 83 Topics: Animals; Blood-Brain Barrier; Brain; Brain Waves; Cell Death; Cyclooxygenase 2; Disease Models, Animal; Electroencephalography; Encephalitis; Gliosis; Isoflurophate; Male; Rats, Sprague-Dawley; Soman; Status Epilepticus; Time Factors; Weight Loss	2021
Comparative profile of refractory status epilepticus models following exposure of cholinergic agents pilocarpine, DFP, and soman. Neuropharmacology, 2021, 06-15, Volume: 191 Topics: Animals; Anticonvulsants; Brain; Brain Injuries; Diazepam; Hippocampus; Isoflurophate; Male; Neurons; Organophosphates; Pilocarpine; Rats; Rats, Sprague-Dawley; Soman; Status Epilepticus	2021