Page last updated: 2024-08-18

soman and diazepam

soman has been researched along with diazepam in 75 studies

Research

Studies (75)

Timeframe	Studies, this research(%)	All Research%
pre-1990	14 (18.67)	18.7374
1990's	34 (45.33)	18.2507
2000's	15 (20.00)	29.6817
2010's	10 (13.33)	24.3611
2020's	2 (2.67)	2.80

Authors

Authors	Studies
Johnson, DD; Wilcox, WC	1
Buccafusco, JJ; Li, W	1
Karlsson, N; Larsson, R; Puu, G	1
de Groot, DM; Melchers, BP; Philippens, IH; Wolthuis, OL	1
Castro, CA; Finger, AV; Larsen, T; McMaster, SB; Solana, RP	1
Holmstedt, B; Karlén, B; Kimland, M; Nordgren, I; Palmér, L	1
Busker, RW; de Lange, J; Melchers, BP; van der Wiel, HJ; van Helden, HP; Wolthuis, OL	1
Capacio, BR; Koviak, TA; Shih, TM	1
Corcoran, KD; Lukey, BJ; Solana, RP	1
Bajgar, J; Fusek, J; Jakl, A; Patocka, J	1
Bokonjić, D; Rosić, N	1
Shih, TM	2
Karlsson, B; Lindgren, B; Millquist, E; Sandberg, M; Sellström, A	1
Lenz, DE; Maxwell, DM; Mills, KR; Petrali, JP	1
Churchill, L; Cross, RS; Nelson, SR; Pazdernik, TL; Samson, FE	1
Hayward, IJ; Jaax, NK; Marlow, DD; Nold, JB; Wade, JV; Wall, HG	1
Bataillard, A; Blanchet, G; Sannajust, F; Sassard, J; Sentenac-Roumanou, H; Yoccoz, D	1
Anthony, A; Doebler, JA; Martin, LJ; Shih, TM; Wall, TJ	1
Crowley, RA; Jaax, NK; Mays, MZ; McDonough, JH; Modrow, HE	1
Chen, J; Cheng, GF; Jiang, ZH; Wang, LP; Zhou, TC	1
Nelson, SR; Pazdernik, TL; Samson, FE; Savolainen, KM	1
Benschop, HP; De Bisschop, HC; Johnson, MK; Read, DJ; Willems, JL	1
Churchill, L; Cross, R; Giesler, M; Nelson, SR; Pazdernik, TL; Samson, FE	1
Flynn, CJ; Wecker, L	1
Anthony, A; Doebler, JA; Martin, LJ; Shih, TM	1
Inns, RH; Leadbeater, L; Rylands, JM	1
Johnson, DD; Lowndes, HE	1
Lipp, JA	1
Inns, RH; Leadbeater, L	1
Bosković, B; Jovanović, D; Kovacević, V	1
Dochterman, LW; McDonough, JH; Shih, TM; Smith, CD	1
Anderson, DR; Bowersox, SL; Carter, WH; Gennings, C; Harris, LW; Lennox, WJ; Solana, RP	2
Anders, JC; Anderson, DR; Bowersox, SL; Harris, LW; Lennox, WJ	1
Blanchet, G; Carpentier, P; Lallement, G; Sentenac-Roumanou, H	1
Baubichon, D; Blanchet, G; Carpentier, P; Collet, A; Lallement, G; Pernot-Marino, I	1
Broxup, B; Clement, JG	1
Koplovitz, I; Stewart, JR	1
Blick, DW; Dunn, MA; Fanton, JW; Hartgraves, SL; Murphy, MR	1
Sket, D	1
Beers, ET; Brennecke, LH; Sparenborg, S	1
McDonough, JH; Shih, TM	1
Baubichon, D; Blanchet, G; Brochier, G; Clarencon, D; Galonnier, M; Lallement, G; Mestries, JC	1
Anderson, DR; Baze, WB; Byers, SL; Capacio, BR; Chang, FC; Harris, LW; Lennox, WJ	1
Baubichon, D; Burckhart, MF; Clarençon, D; Galonnier, M; Lallement, G; Masqueliez, C; Mestries, JC; Peoc'h, M	1
Baubichon, D; Burckhart, MF; Clarençon, D; Galonnier, M; Lallement, G; Peoc'h, M	1
Barrès, C; Bataillard, A; Baubichon, D; Julien, C; Lallement, G; Létienne, R	1
Copeland, TL; McDonough, JH; McMonagle, J; Shih, TM; Smith, CD; Zoeffel, LD	1
Harris, M	1
Little, JS	1
Baubichon, D; Burckhart, MF; Clarençon, D; Galonnier, M; Jourdil, N; Lallement, G; Peoc'h, M; Renault, F	1
Kassa, J	2
Koplovitz, I; Macalalag, R; McDonough, J; Railer, R; Schons, M; Schulz, S; Shutz, M	1
Byers, CE; Capacio, BR; McDonough, JH; Whalley, CE	1
Benjamin, A; McDonough, JH; McMonagle, JD; Rowland, T; Shih, TM	1
Carpentier, P; Dorandeu, F; Foquin, A; Lallement, G	1
Cassel, G; Svensson, I; Waara, L	1
Bhagat, YA; Hamilton, MG; Kendall, EJ; Mikler, J; Obenaus, A	1
Aas, P; Enger, S; Myhrer, T	1
Aas, P; Enger, S; Myhrer, T; Nguyen, NH	1
Bellier, B; Breton, P; Daulon, S; Delamanche, S; Taysse, L	1
McDonough, JH; McMonagle, JD; Shih, TM	1
Liu, L; Mikler, J; Stewart, C; Wang, Y; Weiss, T	1
Bhattacharya, BK; Kumar, S; RamaRao, G; Waghmare, CK	1
Kelley, NR; Lee, RB; Lumley, LA; Moffett, MC; Schultz, MK; Schwartz, JE; Stone, MF; Wright, LK	1
Addis, M; Bailey, K; Chanda, S; de Araujo Furtado, M; Lumley, LA; Moffett, M; Pak, T; Robertson, BD; Rossetti, F; Shields, M; Yourick, DL	1
Apland, JP; Aroniadou-Anderjaska, V; Braga, MF; Figueiredo, TH; Miller, SL; Rossetti, F	1
Apland, JP; Chen, J; Grunberg, N; Marini, AM; McDonough, J; Pan, H; Piermartiri, TC	1
Apland, JP; Aroniadou-Anderjaska, V; Braga, MFM; Figueiredo, TH; Pidoplichko, VI; Rossetti, K	1
Cornelissen, AS; Hesseling, P; Joosen, MJA; Klaassen, SD; Lucassen, PJ; Meerhoff, GF; Vester, SM	1
Bokonjić, D; Jokanović, M; Kilibarda, V; Škrbić, R; Stojiljković, MP; Vulović, M	1
Kuruba, R; Reddy, DS; Wu, X; Zaayman, M	1
Myers, TM; Saxena, A; Sipos, ML	1

Other Studies

75 other study(ies) available for soman and diazepam

Article	Year
Studies on the mechanism of the protective and antidotal actions of diazepam in organophosphate poisoning. European journal of pharmacology, 1975, Volume: 34, Issue:1 Topics: Animals; Antidotes; Atropine; Blood Pressure; Depression, Chemical; Diazepam; Drug Interactions; Heart Rate; Organophosphate Poisoning; Rabbits; Respiration; Soman; Time Factors	1975
Effectiveness of alpha 2-adrenergic receptor stimulation in reducing the central toxicity following cholinesterase inhibition. Research communications in chemical pathology and pharmacology, 1992, Volume: 75, Issue:1 Topics: Adrenergic alpha-Agonists; Animals; Behavior, Animal; Cholinesterase Inhibitors; Clonidine; Diazepam; Dose-Response Relationship, Drug; Guanabenz; Guanfacine; Lethal Dose 50; Male; Motor Activity; Pyridostigmine Bromide; Rats; Rats, Inbred Strains; Soman	1992
Protection of guinea pigs against soman poisoning with ferrocene carbamate. Archives of toxicology, 1992, Volume: 66, Issue:9 Topics: Animals; Atropine; Brain; Cholinesterase Reactivators; Cholinesterases; Diazepam; Ferrous Compounds; Guinea Pigs; Lethal Dose 50; Male; Metallocenes; Organometallic Compounds; Oximes; Physostigmine; Pyridinium Compounds; Soman	1992
Behavioral performance, brain histology, and EEG sequela after immediate combined atropine/diazepam treatment of soman-intoxicated rats. Pharmacology, biochemistry, and behavior, 1992, Volume: 42, Issue:4 Topics: Animals; Atropine; Avoidance Learning; Behavior, Animal; Brain; Diazepam; Electroencephalography; Male; Rats; Rats, Inbred Strains; Seizures; Soman	1992
Behavioral efficacy of diazepam against nerve agent exposure in rhesus monkeys. Pharmacology, biochemistry, and behavior, 1992, Volume: 41, Issue:1 Topics: Acetylcholinesterase; Animals; Behavior, Animal; Cholinesterase Inhibitors; Cholinesterases; Cognition; Diazepam; Discrimination Learning; Macaca mulatta; Soman	1992
Intoxications with anticholinesterases: effect of different combinations of antidotes on the dynamics of acetylcholine in mouse brain. Pharmacology & toxicology, 1992, Volume: 70, Issue:5 Pt 1 Topics: Acetylcholine; Animals; Antidotes; Atropine; Brain; Cholinesterase Inhibitors; Cholinesterase Reactivators; Diazepam; Drug Therapy, Combination; Male; Mice; Oximes; Poisoning; Pyridinium Compounds; Soman	1992
Therapeutic efficacy of HI-6 in soman-poisoned marmoset monkeys. Toxicology and applied pharmacology, 1992, Volume: 115, Issue:1 Topics: Acetylcholinesterase; Animals; Atropine; Brain; Butyrylcholinesterase; Callithrix; Cholinesterase Inhibitors; Cholinesterases; Chromatography, High Pressure Liquid; Diaphragm; Diazepam; Enzyme Activation; Oximes; Poisoning; Pyridinium Compounds; Soman	1992
Anticonvulsants for poisoning by the organophosphorus compound soman: pharmacological mechanisms. Neuroscience and biobehavioral reviews, 1991,Fall, Volume: 15, Issue:3 Topics: Acetylcholine; Animals; Anti-Anxiety Agents; Anticonvulsants; Antidotes; Atropine; Brain Chemistry; Choline; Diazepam; Disease Models, Animal; Dizocilpine Maleate; Gas Chromatography-Mass Spectrometry; Male; Oximes; Parasympatholytics; Poisoning; Pyridinium Compounds; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Seizures; Soman	1991
Pharmacokinetics of diazepam intramuscularly administered to rhesus monkeys. Journal of pharmaceutical sciences, 1991, Volume: 80, Issue:10 Topics: Animals; Anticonvulsants; Blood Proteins; Diazepam; Hematocrit; Injections, Intramuscular; Macaca mulatta; Male; Nordazepam; Protein Binding; Seizures; Soman	1991
Efficacy of various pretreatment and therapy regimens against soman lethality in mice. Sbornik vedeckych praci Lekarske fakulty Karlovy university v Hradci Kralove, 1991, Volume: 34, Issue:3 Topics: Animals; Atropine; Diazepam; Female; Male; Mice; Obidoxime Chloride; Poisoning; Pyridostigmine Bromide; Soman; Trihexyphenidyl; Trimedoxime	1991
Anticonvulsive and protective effects of diazepam and midazolam in rats poisoned by highly toxic organophosphorus compounds. Arhiv za higijenu rada i toksikologiju, 1991, Volume: 42, Issue:4 Topics: Animals; Anticonvulsants; Chemical Warfare Agents; Cholinesterase Inhibitors; Diazepam; Male; Midazolam; Organophosphorus Compounds; Organothiophosphorus Compounds; Rats; Rats, Inbred Strains; Sarin; Soman	1991
Cholinergic actions of diazepam and atropine sulfate in soman poisoning. Brain research bulletin, 1991, Volume: 26, Issue:4 Topics: Acetylcholine; Animals; Atropine; Brain; Cholinesterase Inhibitors; Cholinesterases; Diazepam; Erythrocytes; Male; Motor Activity; Organ Specificity; Parasympathomimetics; Rats; Rats, Inbred Strains; Seizures; Soman	1991
On the use of diazepam and pro-diazepam (2-benzoyl-4-chloro-N-methyl-N-lysylglycin anilide), as adjunct antidotes in the treatment of organophosphorus intoxication in the guinea-pig. The Journal of pharmacy and pharmacology, 1990, Volume: 42, Issue:4 Topics: Animals; Antidotes; Chromatography, Gas; Diazepam; Dipeptides; Guinea Pigs; Injections, Intraperitoneal; Lethal Dose 50; Male; Organophosphate Poisoning; Soman	1990
Effect of an anticholinesterase compound on the ultrastructure and function of the rat blood-brain barrier: a review and experiment. Journal of submicroscopic cytology and pathology, 1991, Volume: 23, Issue:2 Topics: Animals; Blood-Brain Barrier; Brain; Cholinesterase Inhibitors; Diazepam; Hexamethonium Compounds; Horseradish Peroxidase; Male; Pentobarbital; Rats; Rats, Inbred Strains; Seizures; Soman	1991
Soman- or kainic acid-induced convulsions decrease muscarinic receptors but not benzodiazepine receptors. Neurotoxicology, 1990,Spring, Volume: 11, Issue:1 Topics: Animals; Autoradiography; Diazepam; Flunitrazepam; Kainic Acid; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, Muscarinic; Seizures; Soman; Tritium; Video Recording	1990
Decreased brain pathology in organophosphate-exposed rhesus monkeys following benzodiazepine therapy. Journal of the neurological sciences, 1990, Volume: 98, Issue:1 Topics: Animals; Brain; Diazepam; Macaca mulatta; Male; Midazolam; Necrosis; Neurons; Soman	1990
Anticonvulsant effects of diazepam and MK-801 in soman poisoning. Epilepsy research, 1990, Volume: 7, Issue:2 Topics: Animals; Anticonvulsants; Antidotes; Atropine; Diazepam; Dizocilpine Maleate; Dose-Response Relationship, Drug; Male; Oximes; Pyridinium Compounds; Rats; Soman	1990
Cardiovascular consequences of organophosphorus poisoning and of antidotes in conscious unrestrained rats. Pharmacology & toxicology, 1990, Volume: 67, Issue:1 Topics: Animals; Anti-Anxiety Agents; Antidotes; Atropine; Benzodiazepines; Benzodiazepinones; Blood Pressure; Diazepam; Dose-Response Relationship, Drug; Heart Rate; Hemodynamics; Male; Organophosphate Poisoning; Paraoxon; Pralidoxime Compounds; Pyridostigmine Bromide; Rats; Rats, Inbred Strains; Soman	1990
Effects of diazepam on soman-induced brain neuronal RNA depletion and lethality in rats. Life sciences, 1985, Mar-18, Volume: 36, Issue:11 Topics: Acetylcholinesterase; Animals; Brain; Cerebral Cortex; Cholinesterase Inhibitors; Cholinesterases; Corpus Striatum; Diazepam; Lethal Dose 50; Male; Neurons; Organophosphorus Compounds; Rats; Rats, Inbred Strains; RNA; Seizures; Soman	1985
Atropine and/or diazepam therapy protects against soman-induced neural and cardiac pathology. Fundamental and applied toxicology : official journal of the Society of Toxicology, 1989, Volume: 13, Issue:2 Topics: Animals; Atropine; Body Weight; Cholinesterase Inhibitors; Diazepam; Drug Interactions; Heart Diseases; Male; Motor Activity; Nervous System Diseases; Rats; Rats, Inbred Strains; Soman	1989
[Effects of anticonvulsants on the cyclic nucleotide content of the plasma and cerebellum of convulsive rats]. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1987, Volume: 8, Issue:3 Topics: Animals; Anticonvulsants; Cerebellum; Clonazepam; Cyclic AMP; Cyclic GMP; Diazepam; Male; Organophosphorus Compounds; Rats; Scopolamine; Seizures; Soman	1987
Soman-induced convulsions affect the inositol lipid signaling system: potentiation by lithium; attenuation by atropine and diazepam. Toxicology and applied pharmacology, 1988, Volume: 96, Issue:2 Topics: Animals; Atropine; Brain; Diazepam; Drug Interactions; Lithium; Male; Phosphatidylinositols; Rats; Rats, Inbred Strains; Seizures; Signal Transduction; Soman	1988
High doses of soman protect against organophosphorus-induced delayed polyneuropathy but tabun does not. Toxicology and applied pharmacology, 1988, Volume: 92, Issue:1 Topics: Animals; Ataxia; Atropine; Carboxylic Ester Hydrolases; Chickens; Diazepam; Drug Interactions; Female; Isoflurophate; Isomerism; Organophosphates; Organophosphorus Compounds; Physostigmine; Soman	1988
Effects of antidotes on soman-induced brain changes. Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement, 1986, Volume: 9 Topics: Animals; Antidotes; Atropine; Benactyzine; Brain; Diazepam; Glucose; Male; Rats; Rats, Inbred Strains; Seizures; Soman	1986
Concomitant increases in the levels of choline and free fatty acids in rat brain: evidence supporting the seizure-induced hydrolysis of phosphatidylcholine. Journal of neurochemistry, 1987, Volume: 48, Issue:4 Topics: Animals; Brain; Choline; Diazepam; Fatty Acids, Nonesterified; Hydrolysis; Male; Phosphatidylcholines; Rats; Seizures; Soman	1987
Protective effect of diazepam pretreatment on soman-induced brain lesion formation. Brain research, 1985, Jan-28, Volume: 325, Issue:1-2 Topics: Animals; Brain Diseases; Diazepam; Male; Myoclonus; Organophosphorus Compounds; Rats; Rats, Inbred Strains; Soman	1985
Treatment of poisoning by soman. Fundamental and applied toxicology : official journal of the Society of Toxicology, 1985, Volume: 5, Issue:6 Pt 2 Topics: Animals; Antidotes; Atropine; Carbamates; Diazepam; Guinea Pigs; Male; Motor Activity; Organophosphate Poisoning; Parasympatholytics; Phenylpropionates; Physostigmine; Pyridostigmine Bromide; Sarin; Soman; Time Factors	1985
Reduction by diazepam of repetitive electrical activity and toxicity resulting from soman. European journal of pharmacology, 1974, Volume: 28, Issue:2 Topics: Animals; Atropine; Cholinesterase Inhibitors; Diazepam; Drug Synergism; Electrophysiology; Evoked Potentials; In Vitro Techniques; Muscle Contraction; Muscle Tonus; Nerve Endings; Neuromuscular Junction; Phrenic Nerve; Rabbits; Rats; Seizures; Soman	1974
Effect of benzodiazepine derivatives on soman-induced seizure activity and convulsions in the monkey. Archives internationales de pharmacodynamie et de therapie, 1973, Volume: 202, Issue:2 Topics: Animals; Benzazepines; Cholinesterase Inhibitors; Diazepam; Dose-Response Relationship, Drug; Electroencephalography; Female; Haplorhini; Macaca; Male; Nitrazepam; Organophosphorus Compounds; Seizures; Soman; Time Factors	1973
The efficacy of bispyridinium derivatives in the treatment of organophosphonate poisoning in the guinea-pig. The Journal of pharmacy and pharmacology, 1983, Volume: 35, Issue:7 Topics: Animals; Atropine; Diazepam; Female; Guinea Pigs; Obidoxime Chloride; Organophosphate Poisoning; Pyridinium Compounds; Pyridostigmine Bromide; Soman	1983
PAM-2 Cl, HI-6, and HGG-12 in soman and tabun poisoning. Fundamental and applied toxicology : official journal of the Society of Toxicology, 1984, Volume: 4, Issue:2 Pt 2 Topics: Acetylcholinesterase; Animals; Antidotes; Atropine; Cholinesterase Inhibitors; Cholinesterase Reactivators; Diazepam; Dogs; Guinea Pigs; Lethal Dose 50; Male; Mice; Organophosphate Poisoning; Organophosphates; Oximes; Pralidoxime Compounds; Pyridinium Compounds; Rats; Soman; Species Specificity	1984
Protection against nerve agent-induced neuropathology, but not cardiac pathology, is associated with the anticonvulsant action of drug treatment. Neurotoxicology, 1995,Spring, Volume: 16, Issue:1 Topics: Animals; Anticonvulsants; Atropine; Brain; Diazepam; Heart; Male; Myocardium; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Scopolamine; Seizures; Soman; Time Factors	1995
Efficacy comparison of scopolamine and diazepam against soman-induced debilitation in guinea pigs. Fundamental and applied toxicology : official journal of the Society of Toxicology, 1994, Volume: 22, Issue:4 Topics: Animals; Diazepam; Guinea Pigs; Male; Models, Statistical; Scopolamine; Seizures; Soman	1994
Efficacy of injectable anticholinergic drugs against soman-induced convulsive/subconvulsive activity. Drug and chemical toxicology, 1994, Volume: 17, Issue:2 Topics: Animals; Diazepam; Guinea Pigs; Injections, Intramuscular; Male; Parasympatholytics; Random Allocation; Scopolamine; Seizures; Soman	1994
[Prevention and treatment of status epilepticus induced by soman]. Annales pharmaceutiques francaises, 1994, Volume: 52, Issue:1 Topics: Animals; Diazepam; Guinea Pigs; Male; Phencyclidine; Rats; Rats, Wistar; Soman; Status Epilepticus	1994
Transient impairment of the gabaergic function during initiation of soman-induced seizures. Brain research, 1993, Dec-03, Volume: 629, Issue:2 Topics: Animals; Autoradiography; Brain Chemistry; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chloride Channels; Diazepam; Extracellular Space; gamma-Aminobutyric Acid; Hippocampus; Interneurons; Male; Microdialysis; Pyramidal Cells; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, GABA-B; Seizures; Soman	1993
Efficacy of diazepam and avizafone against soman-induced neuropathology in brain of rats. Neurotoxicology, 1993,Winter, Volume: 14, Issue:4 Topics: Animals; Brain; Diazepam; Dipeptides; Molecular Structure; Prodrugs; Rats; Rats, Sprague-Dawley; Seizures; Self Administration; Soman; Time Factors	1993
Efficacy comparison of scopolamine (SCP) and diazepam (DZ) against soman-induced lethality in guinea pigs. Drug and chemical toxicology, 1994, Volume: 17, Issue:1 Topics: Animals; Antidotes; Diazepam; Guinea Pigs; Male; Models, Statistical; Probability; Scopolamine; Soman	1994
A comparison of the efficacy of HI6 and 2-PAM against soman, tabun, sarin, and VX in the rabbit. Toxicology letters, 1994, Feb-15, Volume: 70, Issue:3 Topics: Animals; Antidotes; Atropine; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Diazepam; Lethal Dose 50; Male; Organophosphate Poisoning; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds; Oximes; Poisoning; Pralidoxime Compounds; Pyridinium Compounds; Pyridostigmine Bromide; Rabbits; Sarin; Soman; Specific Pathogen-Free Organisms	1994
Diazepam as a treatment for nerve agent poisoning in primates. Aviation, space, and environmental medicine, 1993, Volume: 64, Issue:2 Topics: Animals; Antidotes; Diazepam; Drug Combinations; Macaca mulatta; Male; Postural Balance; Soman; Task Performance and Analysis	1993
Efficacy of antidotes against soman poisoning in female physostigmine-protected rats. Pharmacology & toxicology, 1993, Volume: 72, Issue:1 Topics: Acetylcholinesterase; Animals; Antidotes; Atropine; Brain; Diazepam; Drug Therapy, Combination; Female; Muscles; Oximes; Physostigmine; Poisoning; Pyridinium Compounds; Rats; Rats, Wistar; Soman	1993
Pharmacological dissociation of the motor and electrical aspects of convulsive status epilepticus induced by the cholinesterase inhibitor soman. Epilepsy research, 1993, Volume: 14, Issue:2 Topics: Analysis of Variance; Animals; Antidotes; Atropine; Brain; Cholinesterase Inhibitors; Diazepam; Electroencephalography; Guinea Pigs; Image Processing, Computer-Assisted; Male; Pralidoxime Compounds; Pyridostigmine Bromide; Scopolamine; Soman; Status Epilepticus	1993
Pharmacological modulation of soman-induced seizures. Neuroscience and biobehavioral reviews, 1993,Summer, Volume: 17, Issue:2 Topics: Animals; Anticonvulsants; Atropine; Behavior, Animal; Benactyzine; Diazepam; Dizocilpine Maleate; Electrodes, Implanted; Electroencephalography; Male; Rats; Rats, Sprague-Dawley; Seizures; Soman; Trihexyphenidyl	1993
Efficacy of atropine/pralidoxime/diazepam or atropine/HI-6/prodiazepam in primates intoxicated by soman. Pharmacology, biochemistry, and behavior, 1997, Volume: 56, Issue:2 Topics: Animals; Antidotes; Atropine; Cholinesterase Inhibitors; Diazepam; Dipeptides; Drug Therapy, Combination; Electrocardiography; Electroencephalography; Macaca fascicularis; Male; Oximes; Poisoning; Pralidoxime Compounds; Prodrugs; Pyridinium Compounds; Soman	1997
Antagonism of soman-induced convulsions by midazolam, diazepam and scopolamine. Drug and chemical toxicology, 1997, Volume: 20, Issue:3 Topics: Animals; Anticonvulsants; Brain; Chemical Warfare Agents; Cholinesterase Inhibitors; Convulsants; Diazepam; Electroencephalography; Electromyography; GABA Modulators; Male; Midazolam; Muscarinic Antagonists; Rats; Rats, Sprague-Dawley; Scopolamine; Seizures; Soman	1997
Nerve agent poisoning in primates: antilethal, anti-epileptic and neuroprotective effects of GK-11. Archives of toxicology, 1998, Volume: 72, Issue:2 Topics: Animals; Anticonvulsants; Atropine; Brain; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Cyclohexanes; Cyclohexenes; Diazepam; Drug Combinations; Excitatory Amino Acid Antagonists; Injections, Intravenous; Macaca fascicularis; Male; Muscarinic Antagonists; Neuroprotective Agents; Piperidines; Pralidoxime Compounds; Seizures; Soman; Staining and Labeling; Time Factors	1998
Acute soman poisoning in primates neither pretreated nor receiving immediate therapy: value of gacyclidine (GK-11) in delayed medical support. Archives of toxicology, 1999, Volume: 73, Issue:2 Topics: Animals; Anticonvulsants; Antidotes; Atropine; Brain; Cerebellum; Cerebral Cortex; Chemical Warfare Agents; Cholinesterase Reactivators; Cyclohexanes; Cyclohexenes; Diazepam; Drug Therapy, Combination; Electrocardiography; Excitatory Amino Acid Antagonists; Haplorhini; Macaca fascicularis; Male; Piperidines; Poisoning; Pralidoxime Compounds; Seizures; Soman; Time Factors	1999
Soman-induced hypertension in conscious rats is mediated by prolonged central muscarinic stimulation. Fundamental & clinical pharmacology, 1999, Volume: 13, Issue:4 Topics: Animals; Anticonvulsants; Atropine; Atropine Derivatives; Blood Pressure; Brain; Cholinesterase Inhibitors; Diazepam; Electroencephalography; Heart Rate; Hypertension; Male; Muscarinic Antagonists; Rats; Rats, Wistar; Seizures; Soman	1999
Anticonvulsant treatment of nerve agent seizures: anticholinergics versus diazepam in soman-intoxicated guinea pigs. Epilepsy research, 2000, Volume: 38, Issue:1 Topics: Animals; Anticonvulsants; Avoidance Learning; Body Weight; Chemical Warfare Agents; Cholinergic Antagonists; Convulsants; Diazepam; Dose-Response Relationship, Drug; Electroencephalography; Guinea Pigs; Male; Nervous System; Soman; Survival Analysis; Time Factors	2000
Call for diazepam replacement. Military medicine, 2000, Volume: 165, Issue:4 Topics: Anticonvulsants; Antidotes; Chemical Warfare Agents; Diazepam; Humans; Lorazepam; Military Medicine; Patient Selection; Seizures; Soman	2000
Diazepam replacement. Military medicine, 2000, Volume: 165, Issue:8 Topics: Anticonvulsants; Chemical Warfare Agents; Diazepam; Humans; Lorazepam; Military Medicine; Seizures; Soman; United States; United States Food and Drug Administration	2000
Compared efficacy of diazepam or avizafone to prevent soman-induced electroencephalographic disturbances and neuropathology in primates: relationship to plasmatic benzodiazepine pharmacokinetics. Archives of toxicology, 2000, Volume: 74, Issue:8 Topics: Animals; Atropine; Brain; Cholinesterase Inhibitors; Diazepam; Dipeptides; Drug Therapy, Combination; Electroencephalography; Macaca fascicularis; Male; Pralidoxime Compounds; Soman	2000
[Effect of diazepam on antidote therapy of lethal toxic effects of soman in rats]. Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti, 2001, Volume: 50, Issue:5 Topics: Animals; Anticonvulsants; Antidotes; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Diazepam; Drug Therapy, Combination; Male; Rats; Rats, Wistar; Soman	2001
[Effect of diazepam on the effectiveness of antidote therapy in eliminating the acute lethal effects of soman in mice]. Casopis lekaru ceskych, 2001, Volume: 140, Issue:16 Topics: Acute Disease; Animals; Anticonvulsants; Antidotes; Atropine; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Diazepam; Male; Mice; Mice, Inbred Strains; Oximes; Poisoning; Pyridinium Compounds; Soman	2001
Combination anticonvulsant treatment of soman-induced seizures. Journal of applied toxicology : JAT, 2001, Volume: 21 Suppl 1 Topics: Animals; Anticonvulsants; Chemical Warfare Agents; Diazepam; Drug Interactions; Drug Therapy, Combination; Electroencephalography; Guinea Pigs; Male; Seizures; Soman	2001
Intramuscular diazepam pharmacokinetics in soman-exposed guinea pigs. Journal of applied toxicology : JAT, 2001, Volume: 21 Suppl 1 Topics: Adsorption; Animals; Anticonvulsants; Chemical Warfare Agents; Diazepam; Dose-Response Relationship, Drug; Guinea Pigs; Injections, Intramuscular; Male; Military Medicine; Poisoning; Soman	2001
Effects of fosphenytoin on nerve agent-induced status epilepticus. Drug and chemical toxicology, 2004, Volume: 27, Issue:1 Topics: Animals; Anticonvulsants; Atropine; Chemical Warfare Agents; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Electroencephalography; Guinea Pigs; Injections, Intraperitoneal; Male; Phenytoin; Pralidoxime Compounds; Pyridostigmine Bromide; Soman; Status Epilepticus	2004
Flunarizine: a possible adjuvant medication against soman poisoning? Drug and chemical toxicology, 2004, Volume: 27, Issue:3 Topics: Animals; Atropine; Brain; Calcium Channel Blockers; Chemical Warfare Agents; Diazepam; Drug Therapy, Combination; Flunarizine; GABA Modulators; Lethal Dose 50; Male; Muscarinic Antagonists; Rats; Rats, Wistar; Seizures; Soman	2004
Effects of HI 6, diazepam and atropine on soman-induced IL-1 beta protein in rat brain. Neurotoxicology, 2005, Volume: 26, Issue:2 Topics: Animals; Atropine; Brain; Diazepam; Drug Therapy, Combination; Electroencephalography; Interleukin-1; Male; Oximes; Pyridinium Compounds; Rats; Rats, Wistar; Seizures; Soman	2005
Neuroprotection from soman-induced seizures in the rodent: evaluation with diffusion- and T2-weighted magnetic resonance imaging. Neurotoxicology, 2005, Volume: 26, Issue:6 Topics: Animals; Anticonvulsants; Brain; Cell Death; Cyclohexanes; Cyclohexenes; Diazepam; Diffusion Magnetic Resonance Imaging; Magnetic Resonance Imaging; Male; Neuroprotective Agents; Piperidines; Rats; Rats, Sprague-Dawley; Seizures; Soman; Status Epilepticus	2005
Efficacy of immediate and subsequent therapies against soman-induced seizures and lethality in rats. Basic & clinical pharmacology & toxicology, 2006, Volume: 98, Issue:2 Topics: Animals; Anticonvulsants; Atropine; Brain; Diazepam; Dipeptides; Drug Combinations; Lethal Dose 50; Male; Oximes; Pentobarbital; Procyclidine; Pyridinium Compounds; Rats; Rats, Wistar; Seizures; Soman	2006
Anticonvulsant effects of GABA(A) modulators microinfused into area tempestas or substantia nigra in rats exposed to soman. Archives of toxicology, 2006, Volume: 80, Issue:8 Topics: Animals; Anticonvulsants; Cerebral Cortex; Chemical Warfare Agents; Diazepam; Drug Therapy, Combination; Ethanol; GABA Agonists; Infusion Pumps; Male; Microinjections; Muscimol; Propofol; Rats; Rats, Wistar; Seizures; Soman; Substantia Nigra	2006
Protection against soman-induced neuropathology and respiratory failure: a comparison of the efficacy of diazepam and avizafone in guinea pig. Toxicology, 2006, Aug-01, Volume: 225, Issue:1 Topics: Animals; Anticonvulsants; Atropine; Brain; Cholinesterase Inhibitors; Diazepam; Dipeptides; Electroencephalography; Guinea Pigs; Neuroprotective Agents; Neurotoxicity Syndromes; Respiratory Insufficiency; Soman	2006
Time-dependent reduction in the anticonvulsant effectiveness of diazepam against soman-induced seizures in guinea pigs. Drug and chemical toxicology, 2010, Volume: 33, Issue:3 Topics: Animals; Anticonvulsants; Chemical Warfare Agents; Diazepam; Electroencephalography; Guinea Pigs; Male; Pilot Projects; Seizures; Soman; Time Factors	2010
Effect of acute soman exposure on GABA(A) receptors in rat hippocampal slices and cultured hippocampal neurons. Neurotoxicity research, 2011, Volume: 20, Issue:4 Topics: Animals; Animals, Newborn; Anticonvulsants; Atropine; Cells, Cultured; Cholinesterase Inhibitors; Diazepam; Dose-Response Relationship, Drug; Electric Stimulation; Embryo, Mammalian; Endocytosis; Enzyme-Linked Immunosorbent Assay; Excitatory Amino Acid Antagonists; Female; Hippocampus; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Membrane Potentials; Microscopy, Confocal; Muscarinic Antagonists; Neurons; Patch-Clamp Techniques; Pregnancy; Protein Transport; Rats; Receptors, GABA-A; Soman; Valine	2011
Gene expression and phosphoprotein profile of certain key neuronal signaling proteins following soman intoxication. Toxicology, 2011, Dec-18, Volume: 290, Issue:2-3 Topics: Acetylcholinesterase; Animals; Atropine; Cerebellum; Chemical Warfare Agents; Cholinesterase Inhibitors; Diazepam; Drug Therapy, Combination; Gene Expression Regulation; Hippocampus; Olfactory Pathways; Oximes; Phosphorylation; Polymerase Chain Reaction; Pyridinium Compounds; Rats; Rats, Wistar; Soman	2011
The anticholinergic and antiglutamatergic drug caramiphen reduces seizure duration in soman-exposed rats: synergism with the benzodiazepine diazepam. Toxicology and applied pharmacology, 2012, Mar-15, Volume: 259, Issue:3 Topics: Acetylcholinesterase; Animals; Anticonvulsants; Body Temperature; Body Weight; Cholinergic Antagonists; Cholinesterase Inhibitors; Cyclopentanes; Diazepam; Dose-Response Relationship, Drug; Drug Synergism; Male; Rats; Rats, Sprague-Dawley; Seizures; Soman; Time Factors	2012
Combined diazepam and HDAC inhibitor treatment protects against seizures and neuronal damage caused by soman exposure. Neurotoxicology, 2012, Volume: 33, Issue:3 Topics: Animals; Anticonvulsants; Brain; Brain Mapping; Brain Waves; Chemical Warfare Agents; Cytoprotection; Diazepam; Drug Therapy, Combination; Electroencephalography; Histone Deacetylase Inhibitors; Hydroxamic Acids; Male; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Seizures; Soman; Time Factors; Valproic Acid; Vorinostat	2012
The limitations of diazepam as a treatment for nerve agent-induced seizures and neuropathology in rats: comparison with UBP302. The Journal of pharmacology and experimental therapeutics, 2014, Volume: 351, Issue:2 Topics: Alanine; Amygdala; Animals; Anticonvulsants; Anxiety; Diazepam; Hippocampus; Male; Nerve Degeneration; Rats; Rats, Sprague-Dawley; Receptors, Kainic Acid; Seizures; Soman; Status Epilepticus; Thymine	2014
Alpha-Linolenic Acid-Induced Increase in Neurogenesis is a Key Factor in the Improvement in the Passive Avoidance Task After Soman Exposure. Neuromolecular medicine, 2015, Volume: 17, Issue:3 Topics: alpha-Linolenic Acid; Animals; Antigens, Nuclear; Atropine Derivatives; Avoidance Learning; Brain Damage, Chronic; Brain-Derived Neurotrophic Factor; Diazepam; DNA Replication; Doublecortin Domain Proteins; Electroshock; Exploratory Behavior; Hippocampus; Male; Mechanistic Target of Rapamycin Complex 1; Microtubule-Associated Proteins; Multiprotein Complexes; Nerve Tissue Proteins; Neurogenesis; Neuropeptides; Neuroprotective Agents; Neurotoxins; Oximes; Proto-Oncogene Proteins c-akt; Pyridinium Compounds; Rats; Rats, Sprague-Dawley; Receptor, trkB; Signal Transduction; Sirolimus; Soman; Status Epilepticus; TOR Serine-Threonine Kinases	2015
Comparing the Antiseizure and Neuroprotective Efficacy of LY293558, Diazepam, Caramiphen, and LY293558-Caramiphen Combination against Soman in a Rat Model Relevant to the Pediatric Population. The Journal of pharmacology and experimental therapeutics, 2018, Volume: 365, Issue:2 Topics: Animals; Anticonvulsants; Anxiety; Basolateral Nuclear Complex; Behavior, Animal; Child; Cyclopentanes; Diazepam; Disease Models, Animal; Drug Interactions; Humans; Isoquinolines; Male; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Soman; Status Epilepticus; Tetrazoles	2018
Potentiation of antiseizure and neuroprotective efficacy of standard nerve agent treatment by addition of tariquidar. Neurotoxicology, 2018, Volume: 68 Topics: Animals; Anticonvulsants; Astrocytes; Atropine; Brain; Cholinesterase Reactivators; Cholinesterases; Diazepam; Male; Microglia; Neurons; Neuroprotective Agents; Oximes; Pyridinium Compounds; Quinolines; Rats, Wistar; Seizures; Soman	2018
Prophylactic potential of memantine against soman poisoning in rats. Toxicology, 2019, 03-15, Volume: 416 Topics: Acetylcholinesterase; Animals; Antidotes; Atropine; Behavior, Animal; Chemical Warfare Agents; Cholinesterase Inhibitors; Diazepam; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; GPI-Linked Proteins; Male; Memantine; Neuromuscular Junction; Organophosphate Poisoning; Oximes; Pyridinium Compounds; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Soman; Synaptic Transmission	2019
Comparative profile of refractory status epilepticus models following exposure of cholinergic agents pilocarpine, DFP, and soman. Neuropharmacology, 2021, 06-15, Volume: 191 Topics: Animals; Anticonvulsants; Brain; Brain Injuries; Diazepam; Hippocampus; Isoflurophate; Male; Neurons; Organophosphates; Pilocarpine; Rats; Rats, Sprague-Dawley; Soman; Status Epilepticus	2021
Conjugates of human serum butyrylcholinesterase and nerve agents are behaviorally safe in rhesus macaques. Chemico-biological interactions, 2021, Aug-01, Volume: 344 Topics: Animals; Butyrylcholinesterase; Diazepam; Female; Humans; Macaca mulatta; Male; Memory; Nerve Agents; Organothiophosphorus Compounds; Soman	2021