Page last updated: 2024-08-18

soman and cyclohexyl methylphosphonofluoridate

soman has been researched along with cyclohexyl methylphosphonofluoridate in 42 studies

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.38)18.7374
1990's2 (4.76)18.2507
2000's12 (28.57)29.6817
2010's21 (50.00)24.3611
2020's6 (14.29)2.80

Authors

AuthorsStudies
Boulet, CA; Hand, BT; Hansen, AS; Lundy, PM1
Dawson, RM; Gray, PJ1
Cheng, TC; DeFrank, JJ; Rastogi, VK1
McDonough, JH; Shih, TM1
Berger, BJ; Davidson, C; Hamilton, MG; Hill, I; Lecavalier, P; Lundy, PM; Vair, C; Weatherby, KL1
Feng, C; Xie, J1
Chenier, CL; D'Agostino, PA; Hancock, JR; Lepage, CR1
Adani, R; Amitai, G; Bel, P; Gaidukov, L; Khersonsky, O; Kushnir, M; Lindenbaum, M; Meshulam, H; Tawfik, DS; Teitlboim, S; Yacov, G; Yishay, S1
Bajgar, J; Jun, D; Kuca, K1
Bajgar, J; Jun, D; Kassa, J; Kuca, K1
Bajgar, J; Jun, D; Karasova, J; Kassa, J; Kuca, K1
Dabisch, PA; Horsmon, MS; Miller, DB; Mioduszewski, RJ; Muse, WT; Sommerville, DR; Taylor, JT; Thomson, S1
Barakat, NH; Beck, JM; Cashman, JR; Gilley, CB; Hadad, CM; MacDonald, M; Okolotowicz, K; Vyas, S; Zhang, J; Zheng, X1
Cashman, JR; Gilley, C; Lockridge, O; MacDonald, M; Nachon, F; Schopfer, LM; Zhang, J1
Blum, MM; Gäb, J; Hellweg, T; Kehe, K; Melzer, M; Wellert, S1
Halamek, E; Hoskovcova, M; Kobliha, Z1
Blum, MM; Gäb, J; John, H; Melzer, M1
Blum, MM; Gäb, J; John, H1
Cashman, JR; Kalisiak, J; Ralph, EC; Zhang, J1
Hamilton, MG; Lundy, PM; Mikler, J; Sawyer, TW1
Barondeau, DP; Bigley, AN; Fox, N; Harvey, SP; Raushel, FM; Tsai, PC1
Cerasoli, DM; Chilukuri, N; Harrison, J; Hodgins, SM; Kasten, SA; Oliver, ZP; Otto, TC; Reeves, TE; Rezk, P1
Bragg, W; Hamelin, EI; Johnson, RC; Shaner, RL; Swaim, LL1
Thiermann, H; Wille, T; Worek, F1
Ringer, JM1
Coleman, RM; Crow, BS; Hamelin, EI; Jakubowski, EM; Johnson, RC; Lawrence, RJ; Schulze, ND; Shaner, RL1
Cashman, JR; Dwyer, M; Javor, S; Ryan, DA; Smith, EM; Wang, B; Zhang, J1
Blake, TA; Brewer, BN; Carter, MD; Crenshaw, MD; Crow, BS; Evans, RA; Garton, JW; Johnson, RC; Pantazides, BG; Perez, JW; Quiñones-González, J; Read, RW; Riches, JR; Stubbs, SJ; Thomas, JD; Tomcik, DJ; Watson, CM1
Cerasoli, DM; Dephillipo, T; Jones, JL; Kasten, SA; Zulli, S1
Aas, P; Enger, S; Mariussen, E; Myhrer, T1
Neumaier, K; Seeger, T; Thiermann, H; Wille, T; Worek, F1
Anslyn, EV; Phillips, ST; Reuther, JF; Sun, X1
da Cunha, EFF; de Castro, AA; Krejcar, O; Kuca, K; Leal, DHS; Mancini, DT; Pereira, AF; Ramalho, TC; Soares, FV1
Brown, AA; Coleman, RM; Hamelin, EI; Johnson, RC; Kaplan, P; Perez, J; Platanitis, K; Schulze, N; Seymour, C; Shaner, RL1
Dagan, S; Elgarisi, M; Madmon, M; Weissberg, A1
Alcaraz, A; Hok, S; Leif, RN; Salazar, EP; Valdez, CA; Vu, AK1
Escher, B; Job, L; Köhler, A; Skerra, A; Worek, F1
Garrett, TJ; Goldberger, BA; Rubin, KM1
Bouknight, KD; Compton, JR; Guelta, MA; Harvey, SP; Jurkouich, KM; Khavrutskii, IV; Legler, PM1
Bird, M; Green, AC; Kassa, J; Tattersall, JEH; Timperley, CM1
Hughes, GT; Kelly, JT; Malloy, TA; Piatkowski, T; Qualley, A; Rubenstein, MH1
Enright, HA; Lao, V; Lau, EY; Malfatti, MA; Mayer, BP; Valdez, CA; Williams, AM1

Reviews

2 review(s) available for soman and cyclohexyl methylphosphonofluoridate

ArticleYear
Alteromonas prolidase for organophosphorus G-agent decontamination.
    Chemico-biological interactions, 1999, May-14, Volume: 119-120

    Topics: Aryldialkylphosphatase; Chemical Warfare Agents; Decontamination; Dipeptidases; Esterases; Gram-Negative Aerobic Bacteria; Organophosphates; Organophosphorus Compounds; Sarin; Soman

1999
Comparative protective effects of HI-6 and MMB-4 against organophosphorous nerve agent poisoning.
    Toxicology, 2011, Jul-29, Volume: 285, Issue:3

    Topics: Antidotes; Chemical Warfare Agents; Humans; Organophosphate Poisoning; Organophosphates; Organophosphorus Compounds; Oximes; Pyridinium Compounds; Sarin; Soman

2011

Other Studies

40 other study(ies) available for soman and cyclohexyl methylphosphonofluoridate

ArticleYear
Comparison of several oximes against poisoning by soman, tabun and GF.
    Toxicology, 1992, Volume: 72, Issue:1

    Topics: Animals; Chemical Warfare Agents; Cholinesterase Inhibitors; Guinea Pigs; Lethal Dose 50; Male; Organophosphates; Organophosphorus Compounds; Oximes; Poisoning; Soman

1992
Kinetic constants for the inhibition of eel and rabbit brain acetylcholinesterase by some organophosphates and carbamates of military significance.
    Toxicology and applied pharmacology, 1987, Volume: 91, Issue:1

    Topics: Animals; Brain; Carbamates; Chemical Warfare Agents; Cholinesterase Inhibitors; Eels; Kinetics; Neostigmine; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds; Physostigmine; Rabbits; Sarin; Soman

1987
Efficacy of biperiden and atropine as anticonvulsant treatment for organophosphorus nerve agent intoxication.
    Archives of toxicology, 2000, Volume: 74, Issue:3

    Topics: Animals; Anticonvulsants; Atropine; Biperiden; Cholinesterase Inhibitors; Cholinesterase Reactivators; Disease Models, Animal; Drug Therapy, Combination; Electroencephalography; Guinea Pigs; Lethal Dose 50; Male; Organophosphates; Organophosphorus Compounds; Pralidoxime Compounds; Pyridostigmine Bromide; Sarin; Seizures; Soman

2000
The pharmacokinetics and pharmacodynamics of two HI-6 salts in swine and efficacy in the treatment of GF and soman poisoning.
    Toxicology, 2005, Mar-30, Volume: 208, Issue:3

    Topics: Animals; Atropine; Chemical Warfare Agents; Dose-Response Relationship, Drug; Guinea Pigs; Male; Neuroprotective Agents; Organophosphate Poisoning; Organophosphorus Compounds; Oximes; Pyridinium Compounds; Soman; Swine; Time Factors

2005
[Determination of five nerve agents in contaminated serum by gas chromatography].
    Se pu = Chinese journal of chromatography, 2005, Volume: 23, Issue:1

    Topics: Chemical Warfare Agents; Chromatography, Gas; Humans; Organophosphorus Compounds; Organothiophosphorus Compounds; Sarin; Serum; Soman

2005
Liquid chromatography electrospray tandem mass spectrometric and desorption electrospray ionization tandem mass spectrometric analysis of chemical warfare agents in office media typically collected during a forensic investigation.
    Journal of chromatography. A, 2006, Mar-31, Volume: 1110, Issue:1-2

    Topics: Central Nervous System Agents; Chemical Warfare Agents; Chromatography, Liquid; Forensic Medicine; Organophosphates; Organophosphorus Compounds; Reproducibility of Results; Sarin; Sensitivity and Specificity; Soman; Specimen Handling; Spectrometry, Mass, Electrospray Ionization; Time Factors

2006
Enhanced stereoselective hydrolysis of toxic organophosphates by directly evolved variants of mammalian serum paraoxonase.
    The FEBS journal, 2006, Volume: 273, Issue:9

    Topics: Animals; Aryldialkylphosphatase; Bacterial Proteins; Decapodiformes; Directed Molecular Evolution; Humans; Hydrolysis; Kinetics; Organophosphorus Compounds; Phosphoric Monoester Hydrolases; Phosphoric Triester Hydrolases; Pseudomonas; Soman; Substrate Specificity

2006
Currently used cholinesterase reactivators against nerve agent intoxication: comparison of their effectivity in vitro.
    Drug and chemical toxicology, 2007, Volume: 30, Issue:1

    Topics: Animals; Brain; Chemical Warfare Agents; Chlorpyrifos; Cholinesterase Inhibitors; Cholinesterase Reactivators; Dose-Response Relationship, Drug; Obidoxime Chloride; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds; Oximes; Pralidoxime Compounds; Pyridinium Compounds; Rats; Rats, Wistar; Sarin; Soman; Tissue Extracts; Trimedoxime

2007
Comparison of reactivating and therapeutic efficacy of two salts of the oxime HI-6 against tabun, soman and cyclosarin in rats.
    Basic & clinical pharmacology & toxicology, 2007, Volume: 101, Issue:5

    Topics: Animals; Atropine; Cholinesterase Inhibitors; Cholinesterase Reactivators; Lethal Dose 50; Male; Muscarinic Antagonists; Organophosphates; Organophosphorus Compounds; Oximes; Pyridinium Compounds; Rats; Soman

2007
A comparison of reactivating efficacy of newly developed oximes (K074, K075) and currently available oximes (obidoxime, HI-6) in soman, cyclosarin and tabun-poisoned rats.
    Chemico-biological interactions, 2008, Sep-25, Volume: 175, Issue:1-3

    Topics: Acetylcholinesterase; Animals; Chemical Warfare Agents; Enzyme Reactivators; Male; Organophosphate Poisoning; Organophosphates; Organophosphorus Compounds; Oximes; Rats; Rats, Wistar; Soman

2008
Gender difference in the miotic potency of soman vapor in rats.
    Cutaneous and ocular toxicology, 2008, Volume: 27, Issue:2

    Topics: Acetylcholinesterase; Analysis of Variance; Animals; Butyrylcholinesterase; Chemical Warfare Agents; Cholinesterase Inhibitors; Eye; Female; Infrared Rays; Male; Miosis; Models, Animal; Organophosphorus Compounds; Organothiophosphorus Compounds; Pupil; Rats; Rats, Sprague-Dawley; Sex Characteristics; Soman

2008
Chemical synthesis of two series of nerve agent model compounds and their stereoselective interaction with human acetylcholinesterase and human butyrylcholinesterase.
    Chemical research in toxicology, 2009, Volume: 22, Issue:10

    Topics: Acetylcholinesterase; Binding Sites; Butyrylcholinesterase; Chemical Warfare Agents; Cholinesterase Inhibitors; Computer Simulation; Humans; Kinetics; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds; Protein Binding; Sarin; Soman; Stereoisomerism

2009
Nerve agent analogues that produce authentic soman, sarin, tabun, and cyclohexyl methylphosphonate-modified human butyrylcholinesterase.
    Chemical research in toxicology, 2009, Volume: 22, Issue:10

    Topics: Amino Acid Sequence; Butyrylcholinesterase; Catalytic Domain; Chemical Warfare Agents; Chromatography, High Pressure Liquid; Humans; Molecular Sequence Data; Organophosphates; Organophosphorus Compounds; Peptides; Sarin; Soman; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Thiocholine; Trypsin

2009
Monitoring the hydrolysis of toxic organophosphonate nerve agents in aqueous buffer and in bicontinuous microemulsions by use of diisopropyl fluorophosphatase (DFPase) with (1)H- (31)P HSQC NMR spectroscopy.
    Analytical and bioanalytical chemistry, 2010, Volume: 396, Issue:3

    Topics: Animals; Biosensing Techniques; Chemical Warfare Agents; Cholinesterase Inhibitors; Convulsants; Hydrolysis; Limit of Detection; Loligo; Magnetic Resonance Spectroscopy; Organophosphorus Compounds; Phosphoric Triester Hydrolases; Sarin; Soman

2010
Efficacy of structural homoloques and isomers of pralidoxime in reactivation of immobilised acetylcholinesterase inhibited with sarin, cyclosarin and soman.
    Neuro endocrinology letters, 2009, Volume: 30 Suppl 1

    Topics: Acetylcholinesterase; Biosensing Techniques; Cholinesterase Inhibitors; Cholinesterase Reactivators; Enzymes, Immobilized; Isomerism; Organophosphorus Compounds; Oximes; Pralidoxime Compounds; Sarin; Soman

2009
Stable adducts of nerve agents sarin, soman and cyclosarin with TRIS, TES and related buffer compounds--characterization by LC-ESI-MS/MS and NMR and implications for analytical chemistry.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2010, May-15, Volume: 878, Issue:17-18

    Topics: Chemical Warfare Agents; Chromatography, Liquid; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Models, Chemical; Organophosphorus Compounds; Sarin; Soman; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Tromethamine

2010
Formation of pyrophosphate-like adducts from nerve agents sarin, soman and cyclosarin in phosphate buffer: implications for analytical and toxicological investigations.
    Toxicology letters, 2011, Jan-15, Volume: 200, Issue:1-2

    Topics: Buffers; Chemical Warfare Agents; Chromatography, High Pressure Liquid; Diphosphates; Hydrolysis; Kinetics; Magnetic Resonance Spectroscopy; Organophosphorus Compounds; Phosphates; Sarin; Soman; Spectrometry, Mass, Electrospray Ionization

2011
Amidine-oximes: reactivators for organophosphate exposure.
    Journal of medicinal chemistry, 2011, May-12, Volume: 54, Issue:9

    Topics: Acetylcholinesterase; Amidines; Animals; Blood-Brain Barrier; Butyrylcholinesterase; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterases; Enzyme Reactivators; Female; Humans; Mice; Organophosphate Poisoning; Organophosphorus Compounds; Oximes; Permeability; Recombinant Proteins; Sarin; Soman; Structure-Activity Relationship

2011
Enzymes for the homeland defense: optimizing phosphotriesterase for the hydrolysis of organophosphate nerve agents.
    Biochemistry, 2012, Aug-14, Volume: 51, Issue:32

    Topics: Bacterial Proteins; Catalysis; Catalytic Domain; Chemical Warfare Agents; Crystallography, X-Ray; Enterobacter aerogenes; Gene Library; High-Throughput Screening Assays; Hydrolysis; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Organophosphorus Compounds; Phosphoric Diester Hydrolases; Phosphoric Triester Hydrolases; Recombinant Proteins; Sarin; Soman; Stereoisomerism

2012
Assessing protection against OP pesticides and nerve agents provided by wild-type HuPON1 purified from Trichoplusia ni larvae or induced via adenoviral infection.
    Chemico-biological interactions, 2013, Mar-25, Volume: 203, Issue:1

    Topics: Animals; Antidotes; Aryldialkylphosphatase; Chemical Warfare Agents; Chlorpyrifos; Guinea Pigs; Humans; Male; Mice; Moths; Organophosphates; Organophosphorus Compounds; Pesticides; Recombinant Proteins; Sarin; Soman

2013
Comparison of high-resolution and tandem mass spectrometry for the analysis of nerve agent metabolites in urine.
    Rapid communications in mass spectrometry : RCM, 2013, Aug-15, Volume: 27, Issue:15

    Topics: Chemical Warfare Agents; Humans; Organophosphorus Compounds; Organothiophosphorus Compounds; Sarin; Soman; Tandem Mass Spectrometry

2013
In vitro kinetics of nerve agent degradation by fresh frozen plasma (FFP).
    Archives of toxicology, 2014, Volume: 88, Issue:2

    Topics: Aryldialkylphosphatase; Aurintricarboxylic Acid; Butyrylcholinesterase; Calcium; Chemical Warfare Agents; Cholinesterase Inhibitors; Edetic Acid; Freezing; Half-Life; Humans; Inactivation, Metabolic; Organophosphates; Organophosphorus Compounds; Plasma; Sarin; Soman

2014
Detection of nerve agents using proton transfer reaction mass spectrometry with ammonia as reagent gas.
    European journal of mass spectrometry (Chichester, England), 2013, Volume: 19, Issue:3

    Topics: Ammonia; Chemical Warfare Agents; Mass Spectrometry; Models, Chemical; Organophosphates; Organophosphonates; Organophosphorus Compounds; Protons; Sarin; Soman; Water

2013
Quantitation of five organophosphorus nerve agent metabolites in serum using hydrophilic interaction liquid chromatography and tandem mass spectrometry.
    Analytical and bioanalytical chemistry, 2014, Volume: 406, Issue:21

    Topics: Ammonium Compounds; Biotransformation; Buffers; Chemical Warfare Agents; Chromatography, High Pressure Liquid; Fluorides; Humans; Hydrophobic and Hydrophilic Interactions; In Vitro Techniques; Limit of Detection; Organophosphorus Compounds; Organothiophosphorus Compounds; Quaternary Ammonium Compounds; Sarin; Solid Phase Extraction; Soman; Tandem Mass Spectrometry

2014
Novel human butyrylcholinesterase variants: toward organophosphonate detoxication.
    Biochemistry, 2014, Jul-15, Volume: 53, Issue:27

    Topics: Butyrylcholinesterase; Butyrylthiocholine; Chemical Warfare Agents; Cholinesterase Inhibitors; Directed Molecular Evolution; Humans; Hydrolysis; Kinetics; Molecular Dynamics Simulation; Organophosphorus Compounds; Recombinant Proteins; Sarin; Soman

2014
Simultaneous measurement of tabun, sarin, soman, cyclosarin, VR, VX, and VM adducts to tyrosine in blood products by isotope dilution UHPLC-MS/MS.
    Analytical chemistry, 2014, Oct-21, Volume: 86, Issue:20

    Topics: Blood Chemical Analysis; Chemical Warfare Agents; Chromatography, High Pressure Liquid; Humans; Organophosphorus Compounds; Organothiophosphorus Compounds; Reproducibility of Results; Sarin; Soman; Spectrometry, Mass, Electrospray Ionization; Time Factors; Tyrosine

2014
Chiral separation of G-type chemical warfare nerve agents via analytical supercritical fluid chromatography.
    Chirality, 2014, Volume: 26, Issue:12

    Topics: Chemical Warfare Agents; Chromatography, Supercritical Fluid; Mass Spectrometry; Organophosphates; Organophosphorus Compounds; Sarin; Soman; Spectrometry, Mass, Electrospray Ionization; Stereoisomerism

2014
Supralethal poisoning by any of the classical nerve agents is effectively counteracted by procyclidine regimens in rats.
    Neurotoxicology, 2015, Volume: 50

    Topics: Animals; Anticonvulsants; Antidotes; Body Weight; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Lethal Dose 50; Levetiracetam; Male; Nerve Agents; Organophosphate Poisoning; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds; Oximes; Piracetam; Procyclidine; Pyridinium Compounds; Rats; Rats, Wistar; Seizures; Soman

2015
Blaptica dubia as sentinels for exposure to chemical warfare agents - a pilot study.
    Toxicology letters, 2016, Nov-16, Volume: 262

    Topics: Animals; Arsenicals; Blister; Chemical Warfare Agents; Cholinesterase Inhibitors; Cockroaches; Female; Male; Mustard Gas; Nerve Agents; Organophosphorus Compounds; Pilot Projects; Sarin; Soman

2016
Coupling Activity-Based Detection, Target Amplification, Colorimetric and Fluorometric Signal Amplification, for Quantitative Chemosensing of Fluoride Generated from Nerve Agents.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2017, Mar-17, Volume: 23, Issue:16

    Topics: Colorimetry; Fluorescent Dyes; Fluorides; Isoflurophate; Nerve Agents; Organophosphorus Compounds; Oximes; Phosphates; Sarin; Soman; Spectrometry, Fluorescence

2017
Theoretical Studies Applied to the Evaluation of the DFPase Bioremediation Potential against Chemical Warfare Agents Intoxication.
    International journal of molecular sciences, 2018, Apr-23, Volume: 19, Issue:4

    Topics: Biodegradation, Environmental; Chemical Warfare Agents; Organophosphates; Organophosphorus Compounds; Phosphoric Triester Hydrolases; Principal Component Analysis; Soman

2018
Investigation of dried blood sampling with liquid chromatography tandem mass spectrometry to confirm human exposure to nerve agents.
    Analytica chimica acta, 2018, Nov-29, Volume: 1033

    Topics: Chromatography, High Pressure Liquid; Chromatography, Liquid; Dried Blood Spot Testing; Humans; Nerve Agents; Organophosphorus Compounds; Organothiophosphorus Compounds; Sarin; Soman; Tandem Mass Spectrometry

2018
Aqueous extraction followed by derivatization and liquid chromatography-mass spectrometry analysis: A unique strategy for trace detection and identification of G-nerve agents in environmental matrices.
    Journal of chromatography. A, 2018, Nov-23, Volume: 1577

    Topics: Chemical Warfare Agents; Chromatography, Liquid; Environmental Monitoring; Gas Chromatography-Mass Spectrometry; Hydrolysis; Limit of Detection; Nerve Agents; Organophosphorus Compounds; Sarin; Soil; Soman; Tandem Mass Spectrometry; Water

2018
Methylation protocol for the retrospective detection of isopropyl-, pinacolyl- and cyclohexylmethylphosphonic acids, indicative markers for the nerve agents sarin, soman and cyclosarin, at low levels in soils using EI-GC-MS.
    The Science of the total environment, 2019, Sep-15, Volume: 683

    Topics: Biomarkers; Gas Chromatography-Mass Spectrometry; Methylation; Nerve Agents; Organophosphorus Compounds; Retrospective Studies; Sarin; Soil; Soil Pollutants; Soman

2019
A catalytic bioscavenger with improved stability and reduced susceptibility to oxidation for treatment of acute poisoning with neurotoxic organophosphorus compounds.
    Toxicology letters, 2020, Mar-15, Volume: 321

    Topics: Antidotes; Bacterial Proteins; Caulobacteraceae; Drug Stability; Enzyme Stability; Hot Temperature; Mutation; Nerve Agents; Organophosphate Poisoning; Organophosphorus Compounds; Organothiophosphorus Compounds; Oxidation-Reduction; Phosphoric Triester Hydrolases; Protein Denaturation; Recombinant Proteins; Sarin; Soman

2020
Detection of Chemical Weapon Nerve Agents in Bone by Liquid Chromatography-Mass Spectrometry.
    Journal of analytical toxicology, 2020, May-18, Volume: 44, Issue:4

    Topics: Animals; Bone and Bones; Chemical Warfare Agents; Chromatography, Liquid; Humans; Limit of Detection; Nerve Agents; Organophosphorus Compounds; Organothiophosphorus Compounds; Sarin; Soman; Swine

2020
Structural and kinetic evidence of aging after organophosphate inhibition of human Cathepsin A.
    Biochemical pharmacology, 2020, Volume: 177

    Topics: Acetylcholinesterase; Binding Sites; Cathepsin A; Cell Line; Chemical Warfare Agents; Cholinesterase Inhibitors; Crystallography, X-Ray; Gene Expression; GPI-Linked Proteins; HEK293 Cells; Humans; Isoflurophate; Kinetics; Models, Molecular; Organophosphorus Compounds; Organothiophosphorus Compounds; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Recombinant Proteins; Sarin; Soman; Substrate Specificity; Time Factors

2020
Influence of experimental end point on the therapeutic efficacy of the antinicotinic compounds MB408, MB442 and MB444 in treating nerve agent poisoned mice - a comparison with oxime-based treatment.
    Toxicology mechanisms and methods, 2020, Volume: 30, Issue:9

    Topics: Animals; Antidotes; Chemical Warfare Agents; Cholinesterase Reactivators; Lethal Dose 50; Male; Mice; Nicotinic Antagonists; Organophosphate Poisoning; Organophosphates; Organophosphorus Compounds; Oximes; Pyridinium Compounds; Sarin; Soman; Time Factors

2020
Improving Quantification of tabun, sarin, soman, cyclosarin, and sulfur mustard by focusing agents: A field portable gas chromatography-mass spectrometry study.
    Journal of chromatography. A, 2021, Jan-11, Volume: 1636

    Topics: Chemical Warfare Agents; Gas Chromatography-Mass Spectrometry; Mustard Gas; Organophosphates; Organophosphorus Compounds; Reference Standards; Sarin; Soman

2021
Evaluation of 6-OxP-CD, an Oxime-based cyclodextrin as a viable medical countermeasure against nerve agent poisoning: Experimental and molecular dynamic simulation studies on its inclusion complexes with cyclosarin, soman and VX.
    PloS one, 2023, Volume: 18, Issue:3

    Topics: Chemical Warfare Agents; Cyclodextrins; Medical Countermeasures; Molecular Dynamics Simulation; Nerve Agents; Organophosphorus Compounds; Oximes; Phosphorus; Soman

2023