Page last updated: 2024-08-18

soman and caramiphen

soman has been researched along with caramiphen in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (18.18)18.2507
2000's1 (9.09)29.6817
2010's6 (54.55)24.3611
2020's2 (18.18)2.80

Authors

AuthorsStudies
Braitman, DJ; Brennecke, LH; Sparenborg, S1
Alkalay, D; Chapman, S; Cohen, G; Gilat, E; Rabinovitz, I; Raveh, L; Weissman, BA1
Alkalay, D; Brandeis, R; Cohen, G; Rabinovitz, I; Raveh, L; Sonego, H; Weissman, BA1
Apland, JP; Aroniadou-Anderjaska, V; Braga, MF; Ferrara, TM; Figueiredo, TH; Pidoplichko, V; Qashu, F; Stevens, D1
Aas, P; Enger, S; Jonassen, M; Myhrer, T1
Kelley, NR; Lee, RB; Lumley, LA; Moffett, MC; Schultz, MK; Schwartz, JE; Stone, MF; Wright, LK1
Aas, P; Enger, S; Myhrer, T1
Apland, JP; Aroniadou-Anderjaska, V; Braga, MFM; Figueiredo, TH; Pidoplichko, VI; Rossetti, K1
Apland, JP; Aroniadou-Anderjaska, V; Braga, MFM; De Araujo Furtado, M; Figueiredo, TH2
Apland, JP; Aroniadou-Anderjaska, V; Braga, MF; Figueiredo, TH; Rossetti, K1

Trials

1 trial(s) available for soman and caramiphen

ArticleYear
Caramiphen and scopolamine prevent soman-induced brain damage and cognitive dysfunction.
    Neurotoxicology, 2002, Volume: 23, Issue:1

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cognition Disorders; Cyclopentanes; Escape Reaction; Hypoxia, Brain; Male; Maze Learning; Prosencephalon; Rats; Rats, Sprague-Dawley; Reaction Time; Scopolamine; Soman; Swimming

2002

Other Studies

10 other study(ies) available for soman and caramiphen

ArticleYear
Prevention of soman neurotoxicity by non-opioid antitussives.
    Neurotoxicology, 1990,Fall, Volume: 11, Issue:3

    Topics: Animals; Anticonvulsants; Antitussive Agents; Cyclopentanes; Dextromethorphan; Guinea Pigs; Male; Necrosis; Nervous System Diseases; Neurons; Soman

1990
The involvement of the NMDA receptor complex in the protective effect of anticholinergic drugs against soman poisoning.
    Neurotoxicology, 1999, Volume: 20, Issue:4

    Topics: Animals; Brain; Cholinesterase Inhibitors; Cyclopentanes; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Electroencephalography; Excitatory Amino Acid Antagonists; Flunitrazepam; In Vitro Techniques; Male; Mice; Mice, Inbred ICR; Parasympatholytics; Protein Binding; Pyridostigmine Bromide; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Scopolamine; Seizures; Soman; Time Factors

1999
Neuroprotective efficacy of caramiphen against soman and mechanisms of its action.
    British journal of pharmacology, 2011, Volume: 164, Issue:5

    Topics: Animals; Behavior, Animal; Brain; Cell Count; Chemical Warfare Agents; Cyclopentanes; Dose-Response Relationship, Drug; Male; Neurons; Neuroprotective Agents; Neurotoxicity Syndromes; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Seizures; Soman; Synaptic Potentials

2011
Enhanced efficacy of anticonvulsants when combined with levetiracetam in soman-exposed rats.
    Neurotoxicology, 2011, Volume: 32, Issue:6

    Topics: Animals; Anticonvulsants; Antidotes; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Cyclopentanes; Disease Models, Animal; Drug Therapy, Combination; Lethal Dose 50; Levetiracetam; Male; Motor Activity; Muscimol; Nicotinic Antagonists; Piracetam; Procyclidine; Quinoxalines; Rats; Rats, Wistar; Reaction Time; Seizures; Soman; Time Factors

2011
The anticholinergic and antiglutamatergic drug caramiphen reduces seizure duration in soman-exposed rats: synergism with the benzodiazepine diazepam.
    Toxicology and applied pharmacology, 2012, Mar-15, Volume: 259, Issue:3

    Topics: Acetylcholinesterase; Animals; Anticonvulsants; Body Temperature; Body Weight; Cholinergic Antagonists; Cholinesterase Inhibitors; Cyclopentanes; Diazepam; Dose-Response Relationship, Drug; Drug Synergism; Male; Rats; Rats, Sprague-Dawley; Seizures; Soman; Time Factors

2012
The perirhinal cortex of rats: an intricate area for microinfusion of anticonvulsants against soman-induced seizures.
    Neurotoxicology, 2013, Volume: 34

    Topics: Animals; Anticonvulsants; Brain Waves; Catheters, Indwelling; Cerebral Cortex; Cyclopentanes; Cyclopropanes; Disease Models, Animal; Drug Delivery Systems; Electroencephalography; Glycine; Infusions, Parenteral; Male; Micromanipulation; Procyclidine; Pyridines; Rats; Rats, Wistar; Reaction Time; Seizures; Soman; Time Factors

2013
Comparing the Antiseizure and Neuroprotective Efficacy of LY293558, Diazepam, Caramiphen, and LY293558-Caramiphen Combination against Soman in a Rat Model Relevant to the Pediatric Population.
    The Journal of pharmacology and experimental therapeutics, 2018, Volume: 365, Issue:2

    Topics: Animals; Anticonvulsants; Anxiety; Basolateral Nuclear Complex; Behavior, Animal; Child; Cyclopentanes; Diazepam; Disease Models, Animal; Drug Interactions; Humans; Isoquinolines; Male; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Soman; Status Epilepticus; Tetrazoles

2018
Full Protection Against Soman-Induced Seizures and Brain Damage by LY293558 and Caramiphen Combination Treatment in Adult Rats.
    Neurotoxicity research, 2018, Volume: 34, Issue:3

    Topics: Animals; Anticonvulsants; Body Weight; Brain Injuries; Brain Waves; Cholinesterase Inhibitors; Cyclopentanes; Disease Models, Animal; Drug Therapy, Combination; Electroencephalography; Fluoresceins; Fourier Analysis; Isoquinolines; Male; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Seizures; Soman; Tetrazoles; Time Factors

2018
Electroencephalographic analysis in soman-exposed 21-day-old rats and the effects of midazolam or LY293558 with caramiphen.
    Annals of the New York Academy of Sciences, 2020, Volume: 1479, Issue:1

    Topics: Animals; Antidotes; Cyclopentanes; Electrocardiography; Isoquinolines; Male; Midazolam; Nerve Agents; Rats; Rats, Sprague-Dawley; Soman; Status Epilepticus; Tetrazoles

2020
Delayed tezampanel and caramiphen treatment but not midazolam protects against long-term neuropathology after soman exposure.
    Experimental biology and medicine (Maywood, N.J.), 2023, Volume: 248, Issue:7

    Topics: Animals; Anticonvulsants; Brain; Brain Injuries; Female; Male; Midazolam; Nerve Agents; Rats; Seizures; Soman; Status Epilepticus

2023