Compounds > solutol hs 15
Page last updated: 2024-09-03

solutol hs 15 and paclitaxel

solutol hs 15 has been researched along with paclitaxel in 4 studies

Compound Research Comparison

Studies
(solutol hs 15)		Trials
(solutol hs 15)		Recent Studies (post-2010)
(solutol hs 15)		Studies
(paclitaxel)		Trials
(paclitaxel)		Recent Studies (post-2010) (paclitaxel)
9215931,8745,72915,395

Protein Interaction Comparison

ProteinTaxonomysolutol hs 15 (IC50)paclitaxel (IC50)
Integrin beta-3Homo sapiens (human)0.034
Integrin alpha-V Homo sapiens (human)0.034
ATP-dependent translocase ABCB1Homo sapiens (human)2.598
Botulinum neurotoxin type A Clostridium botulinum5.2
UDP-glucuronosyltransferase 2B7Homo sapiens (human)4.9
UDP-glucuronosyltransferase 1-6Homo sapiens (human)4.9
Substance-K receptorHomo sapiens (human)6.125
UDP-glucuronosyltransferase 1A1 Homo sapiens (human)4.9
UDP-glucuronosyltransferase 1A4Homo sapiens (human)4.9
UDP-glucuronosyltransferase 2B10 Homo sapiens (human)4.9
Delta-type opioid receptorHomo sapiens (human)4.202
Tyrosine-protein kinase MerHomo sapiens (human)4.9
Tubulin beta-3 chainHomo sapiens (human)0.0082
Beta-tubulin Leishmania donovani1
Nucleotide-binding oligomerization domain-containing protein 2Homo sapiens (human)7.9433
Solute carrier organic anion transporter family member 1B3Homo sapiens (human)0.26
Solute carrier organic anion transporter family member 1B1Homo sapiens (human)0.28

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alani, AW; Jiao, J; Kwon, GS; Rao, DA; Seidel, R; Wang, J1
Chen, L; Deng, Y; Gao, Y; Ji, X; Li, Y; Zhang, Z1
Hou, J; Jia, XB; Sun, C; Sun, E; Wang, J; Yang, L; Zhang, ZH1
Li, W; Xu, H; Xue, J1

Other Studies

4 other study(ies) available for solutol hs 15 and paclitaxel

ArticleYear
The effect of novel surfactants and Solutol HS 15 on paclitaxel aqueous solubility and permeability across a Caco-2 monolayer.
    Journal of pharmaceutical sciences, 2010, Volume: 99, Issue:8

    Topics: Antineoplastic Agents, Phytogenic; Caco-2 Cells; Cell Membrane Permeability; Chromatography, High Pressure Liquid; Humans; L-Lactate Dehydrogenase; Light; Mannitol; Micelles; Paclitaxel; Polyethylene Glycols; Scattering, Radiation; Solubility; Stearic Acids; Surface-Active Agents

2010
Nanohybrid systems of non-ionic surfactant inserting liposomes loading paclitaxel for reversal of multidrug resistance.
    International journal of pharmaceutics, 2012, Jan-17, Volume: 422, Issue:1-2

    Topics: Adenosine Triphosphate; Antineoplastic Agents, Phytogenic; Apoptosis; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Cycle; Cell Line, Tumor; Chemistry, Pharmaceutical; Dose-Response Relationship, Drug; Drug Compounding; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Glycerol; Humans; Lipids; Liposomes; Lung Neoplasms; Nanotechnology; Paclitaxel; Particle Size; Poloxamer; Polyethylene Glycols; Rhodamine 123; Solubility; Stearic Acids; Surface-Active Agents; Technology, Pharmaceutical; Time Factors

2012
Improved oral bioavailability and anticancer efficacy on breast cancer of paclitaxel via Novel Soluplus(®)-Solutol(®) HS15 binary mixed micelles system.
    International journal of pharmaceutics, 2016, Oct-15, Volume: 512, Issue:1

    Topics: Administration, Oral; Animals; Biological Availability; Cell Line, Tumor; Cell Survival; Drug Carriers; Drug Liberation; Male; Mice; Micelles; Paclitaxel; Polyethylene Glycols; Polymers; Polyvinyls; Rats; Stearic Acids; Xenograft Model Antitumor Assays

2016
Combined administration of PTX and S-HM-3 in TPGS/Solutol micelle system for oncotarget therapy.
    International journal of nanomedicine, 2019, Volume: 14

    Topics: Animals; Antineoplastic Agents; Cell Death; Cell Line, Tumor; Cell Movement; Drug Carriers; Female; Humans; Inhibitory Concentration 50; Male; Mice, Inbred BALB C; Mice, Nude; Micelles; Neoplasms; Paclitaxel; Polyethylene Glycols; Stearic Acids; Tissue Distribution; Tumor Burden; Vitamin E; Whole Body Imaging

2019