solifenacin succinate has been researched along with carbachol in 8 studies
| Studies (solifenacin succinate) | Trials (solifenacin succinate) | Recent Studies (post-2010) (solifenacin succinate) | Studies (carbachol) | Trials (carbachol) | Recent Studies (post-2010) (carbachol) |
|---|---|---|---|---|---|
| 522 | 194 | 343 | 13,918 | 81 | 968 |
| Protein | Taxonomy | solifenacin succinate (IC50) | carbachol (IC50) |
|---|---|---|---|
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | 0.7849 | |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | 2.0626 | |
| Muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | 3.4134 | |
| Muscarinic acetylcholine receptor M3 | Rattus norvegicus (Norway rat) | 2.9961 | |
| Muscarinic acetylcholine receptor M4 | Rattus norvegicus (Norway rat) | 2.535 | |
| Muscarinic acetylcholine receptor M5 | Rattus norvegicus (Norway rat) | 2.9961 | |
| Muscarinic acetylcholine receptor M2 | Rattus norvegicus (Norway rat) | 2.6638 | |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | 4.849 | |
| Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | 4.99 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (75.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Honda, K; Ikeda, K; Kobayashi, S; Miyata, K; Suzuki, M; Takeuchi, M; Yamada, T | 1 |
| Ikeda, K; Kobayashi, S; Miyata, K | 1 |
| Hatanaka, T; Miyata, K; Noguchi, Y; Ohtake, A; Okutsu, H; Saitoh, C; Sasamata, M; Sato, S; Suzuki, M; Ukai, M; Yuyama, H | 1 |
| Chugh, A; Gupta, JB; Hegde, LG; Kumar, N; Meru, AV; Naruganahalli, KS; Ray, A; Sinha, S | 1 |
| Noguchi, Y; Ohtake, A; Okutsu, H; Sasamata, M; Sato, S; Suzuki, M | 1 |
| Inadome, A; Maeda, Y; Masunaga, K; Murakami, S; Satoji, Y; Sugiyama, Y; Ueda, S; Yoshida, M | 1 |
| Chess-Williams, R; Moro, C; Uchiyama, J | 1 |
| Chess-Williams, R; McDermott, C; Sellers, DJ; West, EG | 1 |
8 other study(ies) available for solifenacin succinate and carbachol
| Article | Year |
|---|---|
M(3) receptor antagonism by the novel antimuscarinic agent solifenacin in the urinary bladder and salivary gland.
Topics: Animals; Benzofurans; Bradycardia; Calcium; Carbachol; Cells, Cultured; Cytosol; Dose-Response Relationship, Drug; Female; Guinea Pigs; Humans; In Vitro Techniques; Isoquinolines; Kinetics; Male; Mandelic Acids; Mice; Mice, Inbred BALB C; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Pyrrolidines; Quinuclidines; Rats; Receptor, Muscarinic M3; Receptors, Muscarinic; Salivary Glands; Solifenacin Succinate; Tetrahydroisoquinolines; Urinary Bladder | 2002 |
Comparison of in vitro selectivity profiles of solifenacin succinate (YM905) and current antimuscarinic drugs in bladder and salivary glands: a Ca2+ mobilization study in monkey cells.
Topics: Animals; Benzhydryl Compounds; Benzofurans; Calcium; Calcium Signaling; Carbachol; Cresols; Dose-Response Relationship, Drug; In Vitro Techniques; Inhibitory Concentration 50; Macaca fascicularis; Male; Mandelic Acids; Muscarinic Antagonists; Phenylpropanolamine; Pyrrolidines; Quinuclidines; Solifenacin Succinate; Submandibular Gland; Tetrahydroisoquinolines; Tolterodine Tartrate; Urinary Bladder | 2004 |
Pharmacological characterization of a new antimuscarinic agent, solifenacin succinate, in comparison with other antimuscarinic agents.
Topics: Animals; Atropine; Benzhydryl Compounds; Benzilates; Benzofurans; Binding, Competitive; Carbachol; CHO Cells; Cholinergic Agonists; Cresols; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Mandelic Acids; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; N-Methylscopolamine; Phenylpropanolamine; Pyrrolidines; Quinuclidines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Muscarinic; Solifenacin Succinate; Tetrahydroisoquinolines; Tolterodine Tartrate; Transfection; Urinary Bladder; Urinary Bladder, Overactive; Urination | 2007 |
Comparative in vivo uroselectivity profiles of anticholinergics, tested in a novel anesthetized rabbit model.
Topics: Anesthesia; Animals; Benzhydryl Compounds; Benzofurans; Carbachol; Cholinergic Antagonists; Cresols; Injections, Intra-Arterial; Male; Mandelic Acids; Phenylpropanolamine; Pressure; Pyrrolidines; Quinuclidines; Rabbits; Salivary Glands; Solifenacin Succinate; Tetrahydroisoquinolines; Tolterodine Tartrate; Urinary Bladder | 2007 |
Effects of intravenously and orally administered solifenacin succinate (YM905) on carbachol-induced intravesical pressure elevation and salivary secretion in mice.
Topics: Administration, Oral; Anesthesia; Animals; Blood Pressure; Carbachol; Injections, Intravenous; Mice; Muscarinic Agonists; Muscarinic Antagonists; Quinuclidines; Salivation; Solifenacin Succinate; Tetrahydroisoquinolines | 2007 |
Pharmacological effects of solifenacin on human isolated urinary bladder.
Topics: Aged; Calcium Chloride; Carbachol; Dose-Response Relationship, Drug; Electric Stimulation; Female; Humans; In Vitro Techniques; Male; Microdialysis; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Potassium Chloride; Quinuclidines; Solifenacin Succinate; Tetrahydroisoquinolines; Urinary Bladder | 2008 |
Urothelial/lamina propria spontaneous activity and the role of M3 muscarinic receptors in mediating rate responses to stretch and carbachol.
Topics: Animals; Atropine; Benzhydryl Compounds; Benzofurans; Carbachol; Cresols; Diamines; Mandelic Acids; Mucous Membrane; Muscarinic Antagonists; Muscle Contraction; Phenylpropanolamine; Piperidines; Pirenzepine; Pyrrolidines; Quinuclidines; Receptor, Muscarinic M3; Solifenacin Succinate; Stress, Mechanical; Swine; Tetrahydroisoquinolines; Tolterodine Tartrate; Urinary Bladder; Urothelium | 2011 |
Mirabegron and solifenacin are effective for the management of the increased urinary frequency induced by psychological stress in female mice.
Topics: Acetanilides; Animals; Carbachol; Female; Mice; Muscarinic Antagonists; Solifenacin Succinate; Stress, Psychological; Thiazoles; Treatment Outcome; Urinary Bladder, Overactive | 2022 |