Page last updated: 2024-08-23

solanine and alpha-solanine

solanine has been researched along with alpha-solanine in 75 studies

Research

Studies (75)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	12 (16.00)	29.6817
2010's	50 (66.67)	24.3611
2020's	13 (17.33)	2.80

Authors

Authors	Studies
Fogelman, E; Ginzberg, I; Krits, P	1
Hansen, HC; Hansen, TH; Jacobsen, OS; Jensen, PH; Juhler, RK; Nielsen, J; Nielsen, NJ; Strobel, BW	1
Christiansen, J; Kirk, HG; Labouriau, R; Olsson, K; Sørensen, KK	1
Dinkins, CL; Peterson, RK	1
Conner, S; Davies, H; Langkilde, S; Meyer, O; Poulsen, M; Schrøder, M; Stewart, D	1
Langkilde, S; Mandimika, T; Meyer, O; Peijnenburg, A; Poulsen, M; Schrøder, M; Slob, W	1
Hansen, HC; Jacobsen, OS; Jensen, PH; Strobel, BW	1
Boon, PE; Bosgra, S; Busk, L; Moussavian, S; Rehurkova, I; Ruprich, J; Svensson, K; Van der Voet, H; Van Klaveren, JD	1
Hansen, HC; Henriksen, T; Jacobsen, OS; Jensen, PH; Strobel, BW	1
Andolfi, A; Carputo, D; Cimmino, A; Evidente, A; Frusciante, L; Savarese, S	1
Hansen, HC; Jacobsen, OS; Jensen, PH; Pedersen, RB; Strobel, BW; Svensmark, B	1
Kroh, LW; Mäder, J; Rawel, H	1
Cahill, MG; Caprioli, G; James, KJ; Vittori, S	1
Chang Chien, TT; Chen, PS; Fang, LH; Huang, HC; Lu, MK; Shih, YW	1
Ambrosino, P; Lanzuise, S; Lorito, M; Ruocco, M; Scala, F; Woo, SL	1
Demirel, U; Fogelman, E; Ginzberg, I; Mweetwa, AM; Thippeswamy, M; Tokuhisa, J; Veilleux, RE	1
Asghar, A; Aziz, A; Butt, MS; Randhawa, MA; Shibamoto, T; Yasin, M	1
Belknap, WR; Conner, S; Danier, J; Davies, HV; Engel, KH; Frank, T; Knudsen, I; Langkilde, S; McCue, KF; Meyer, O; Poulsen, M; Rychlik, M; Schrøder, M; Shepherd, LV; Stewart, D	1
Attoumbré, J; Baltora-Rosset, S; Giordanengo, P; Lesur, D	1
Bengtsson, M; Birgersson, G; Karlsson, MF; Lekfeldt, JD; Nimal Punyasiri, PA; Witzgall, P	1
Brunton, NP; Collins, SG; Hossain, MB; Jones, PW; Kenny, OM; Maguire, AR; McCarthy, CM; O'Brien, NM; Rai, DK	1
Adamski, Z; Bufo, SA; Büyükgüzel, E; Büyükgüzel, K; Erdem, M; Marciniak, P; Scrano, L; Ventrella, E; Ziemnicki, K	1
Andersson, HC; Arif, U; Hajšlová, J; Jonsson, L; Krtková, V; Meijer, J; Petersson, EV; Schulzova, V; Sitbon, F	1
Matsuda, T; Yamashoji, S	1
Alizadeh, AM; Azizian, S; Karimi, A; Khodayari, H; Khodayari, S; Kouhpayeh, SA; Mohagheghi, MA; Mohsenikia, M; Zamani, M	1
Chen, B; Dong, G; Kong, H; Liu, L; Lv, C; Sun, H; Tong, K; Zhang, C; Zhou, M	1
Gaffney, M; O'Brien, N; Reilly, K; Valcarcel, J	1
Chira, A; Espinoza, MA; Istamboulie, G; Marty, JL; Noguer, T; Stoytcheva, M	1
Adamski, Z; Bufo, SA; Büyükgüzel, E; Büyükgüzel, K; Cristallo, M; Erdem, M; Falabella, P; Marciniak, P; Salvia, R; Scrano, L; Ventrella, E; Ziemnicki, K	1
Chen, PS; Hu, KC; Hung, JH; Lee, WJ; Liao, AC; Liao, RF; Lin, PT; Shen, KH	1
Cai, X; Zhang, X	1
Ali-Rachedi, F; Chambert, S; Cowling, SJ; Davis, EJ; Ferkous, F; Goodby, JW; Queneau, Y; Xavier, NM; Xu, R	1
Friedman, M	1
Aguiló-Aguayo, I; Brunton, NP; Hossain, MB; Rai, DK; Rawson, A	1
Ashraf, R; Bhattacharjee, A; Datta, D; Hasanain, M; Mitra, K; Pandey, P; Sarkar, J; Sharma, S; Singh, N; Vishwakarma, AL	1
Bai, Y; Chen, S; Chen, X; Cheng, R; Li, H; Li, J; Li, P; Lu, X; Sun, Q; Wu, S; Yang, R; Zhang, F; Zhang, G; Zhao, G; Zhao, H	1
Chen, B; Dai, J; Huang, C; Sun, H; Tang, L; Wen, Z; Xiao, Y; Xu, Y; Zhou, M	1
de Oliveira, LA; Frazzon, J; Hutten, RC; Kok, EJ; Mariot, RF; Staats, M; van Dijk, JP; Voorhuijzen, MM	1
Gänzle, MG; Sánchez-Maldonado, AF; Schieber, A	1
Alexander, CJ; Belknap, WR; Davies, HV; Hackett, CA; McCue, KF; McNicol, JW; McRae, D; Shepherd, LV; Sungurtas, JA	1
An, HJ; Jang, DS; Lee, HH; Lee, HJ; Lee, KG; Lee, KT; Nam, JH; Shin, JS	1
Brunton, NP; Hossain, MB; Rai, DK	1
Adamski, Z; Bufo, SA; Büyükgüzel, E; Büyükgüzel, K; Chudzińska, E; Erdem, M; Falabella, P; Marciniak, P; Miądowicz-Kobielska, M; Scrano, L; Ventrella, E	1
Mizutani, M; Muranaka, T; Nakayasu, M; Ohyama, K; Saito, K; Seki, H; Umemoto, N; Yotsu-Yamashita, M	1
Chen, X; Dong, Z; Guo, W; Sun, Q; Wang, Y; Wu, J; Zang, W; Zhao, G	1
Bulone, V; Dahlin, P; Ekengren, S; McKee, LS; Müller, MC	1
Chang, Y; Chen, J; Chen, Y; Dai, Y; Mao, W; Nie, X; Qin, G; Tan, J; Wang, Q; Zou, J	1
Cheng, X; Jin, E; Li, X; Narisawa, M	1
Baek, JJ; Cho, ES; Jeong, YD; Jin, DI; Kang, JW; Kim, SY; Lee, JE; Lin, T; Oqani, RK	1
Du, X; Li, M; Liu, K; Sun, Q; Wang, L; Wang, Y; Wu, J; Zang, W; Zhao, G	1
Bai, J; Gao, S; Ji, Y; Lang, L; Tan, H	1
Chen, J; Hu, Z; Jiang, L; Lu, F; Ni, X; Xu, X; Yuan, Z	1
Akiyama, R; Lee, HJ; Mizutani, M; Muranaka, T; Nakayasu, M; Osakabe, K; Osakabe, Y; Saito, K; Sugimoto, Y; Umemoto, N; Watanabe, B	1
Karaboğa Arslan, AK; Yerer, MB	1
Butt, G; Farooqi, AA; Romero, MA; Tahir, F	1
Ameline, A; Attoumbré, J; Beaulieu, R; Chesnais, Q; Giordanengo, P; Gobert, V; Grand, E; Kovensky, J; Stasik, I	1
Brennan, C; Guan, W; Jia, B; Lin, Q; Xu, L; Yan, R; Zhao, H	1
Gao, M; Mao, L; Wang, S; Wen, W; Xue, X; Yao, L; Zhang, X	1
Hao, T; Sun, J; Wei, P; Yang, J; Zhang, H	1
Lim, W; Park, MY; Park, S; Song, G	1
Abdel Hamid, FF; Ashour, MN; El-Daly, SM; Gamal-Eldeen, AM; Gouhar, SA; Hassan, NS	1
Chen, Z; Kang, Y; Qin, S; Zhang, W; Zuo, C	1
Greve-Poulsen, M; Hennessy, RC; Larsen, LB; Nielsen, SD; Stougaard, P; Sørensen, OB	1
An, HM; Chen, L; Hu, B; Li, M; Peng, X; Que, ZJ; Shen, KP; Yan, X	1
Helander, M; Lindström, L; Margus, A; Rainio, MJ; Saikkonen, K; Salminen, JP; Virtanen, V	1
Gul, S; Hassan, SH; Irfan, M; Khan, M; Maryam, A; Shakir, HA; Zahra, HS	1
Chen, Z; Fan, X; Gu, T; Li, C; Wu, X; Xiong, X; Yang, Q; Yuan, A; Zhang, F	1
Akiyama, R; Kato, J; Lee, HJ; Mizutani, M; Muranaka, T; Nakayasu, M; Saito, K; Sugimoto, Y; Umemoto, N; Watanabe, B	1
Chen, Z; Gu, T; Li, C; Wen, Y; Xiong, X; Yang, Q; Yuan, A; Yuan, W; Zheng, Q	1
Akiyama, R; Lee, HJ; Miyachi, H; Mizutani, M; Muranaka, T; Nakayasu, M; Ohyama, K; Saito, K; Sugimoto, Y; Umemoto, N; Watanabe, B	1
Bhattacharya, E; Mandal Biswas, S; Pramanik, P	1
Abo-Elfadl, MT; El-Daly, SM; Gamal-Eldeen, AM; Gouhar, SA	1
Chen, Y; Du, F; Gu, L; Li, M; Shen, J; Wei, J; Wu, X; Wu, Z; Xiao, Z; Yang, L; Ye, Y; Zhao, Y; Zou, T	1
Adamski, Z; Bufo, SA; Chowański, S; Mańczak, D; Marciniak, P; Scrano, L; Spochacz, M; Szymczak-Cendlak, M; Walkowiak-Nowicka, K; Winkiel, M	1
Earl, K; Eltayeb, HA; Jackson, D; Johnson, T; Morgem, M; Nguyen, M; Olufemi, SE; Sodipe, A; Stewart, L	1

Reviews

3 review(s) available for solanine and alpha-solanine

Article	Year
Chemistry and anticarcinogenic mechanisms of glycoalkaloids produced by eggplants, potatoes, and tomatoes. Journal of agricultural and food chemistry, 2015, Apr-08, Volume: 63, Issue:13 Topics: Animals; Anticarcinogenic Agents; Apoptosis; Cell Line, Tumor; Humans; Mice; Solanaceous Alkaloids; Solanine; Solanum lycopersicum; Solanum melongena; Solanum tuberosum; Structure-Activity Relationship; Tomatine	2015
Emerging themes of regulation of oncogenic proteins by Solanum nigrum and its bioactive molecules in different cancers. Journal of cellular biochemistry, 2018, Volume: 119, Issue:12 Topics: Animals; Antineoplastic Agents, Phytogenic; Female; Gene Expression Regulation, Neoplastic; Hedgehog Proteins; Humans; Liver Neoplasms; Male; MicroRNAs; Oncogene Proteins; Ovarian Neoplasms; Prostatic Neoplasms; Solanine; Solanum nigrum	2018
Alpha Solanine: A Novel Natural Bioactive Molecule with Anticancer Effects in Multiple Human Malignancies. Nutrition and cancer, 2021, Volume: 73, Issue:9 Topics: Humans; Neoplasms; Signal Transduction; Solanine; Solanum tuberosum	2021

Other Studies

72 other study(ies) available for solanine and alpha-solanine

Article	Year
Potato steroidal glycoalkaloid levels and the expression of key isoprenoid metabolic genes. Planta, 2007, Volume: 227, Issue:1 Topics: Gene Expression Regulation, Plant; Genes, Plant; Genotype; Models, Biological; Plant Leaves; Reverse Transcriptase Polymerase Chain Reaction; Solanaceous Alkaloids; Solanine; Solanum tuberosum; Terpenes	2007
Potato glycoalkaloids in soil-optimising liquid chromatography-time-of-flight mass spectrometry for quantitative studies. Journal of chromatography. A, 2008, Feb-22, Volume: 1182, Issue:1 Topics: Chromatography, Liquid; Molecular Structure; Reproducibility of Results; Soil; Solanaceous Alkaloids; Solanine; Solanum tuberosum; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization	2008
A major QTL and an SSR marker associated with glycoalkaloid content in potato tubers from Solanum tuberosum x S. sparsipilum located on chromosome I. TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik, 2008, Volume: 117, Issue:1 Topics: Amplified Fragment Length Polymorphism Analysis; Breeding; Chromatography, High Pressure Liquid; Chromosome Mapping; Chromosomes, Plant; Diploidy; DNA, Plant; Genetic Linkage; Genetic Markers; Light; Phenotype; Plant Tubers; Polymerase Chain Reaction; Principal Component Analysis; Quantitative Trait Loci; Repetitive Sequences, Nucleic Acid; Solanine; Solanum tuberosum	2008
A human dietary risk assessment associated with glycoalkaloid responses of potato to Colorado potato beetle defoliation. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2008, Volume: 46, Issue:8 Topics: Adolescent; Adult; Animals; Child; Child, Preschool; Coleoptera; Diet; Dose-Response Relationship, Drug; Eating; Female; Humans; Infant; Lethal Dose 50; Male; No-Observed-Adverse-Effect Level; Pregnancy; Risk Assessment; Solanine; Solanum tuberosum	2008
Acute toxicity of high doses of the glycoalkaloids, alpha-solanine and alpha-chaconine, in the Syrian Golden hamster. Journal of agricultural and food chemistry, 2008, Sep-24, Volume: 56, Issue:18 Topics: Acetylcholinesterase; Animals; Butyrylcholinesterase; Cricetinae; Dose-Response Relationship, Drug; Female; Intestine, Small; Mesocricetus; Solanine	2008
A 28-day repeat dose toxicity study of steroidal glycoalkaloids, alpha-solanine and alpha-chaconine in the Syrian Golden hamster. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2009, Volume: 47, Issue:6 Topics: Acetylcholinesterase; Animals; Biological Availability; Blood Cell Count; Blood Chemical Analysis; Body Weight; Butyrylcholinesterase; Cholinesterases; Cricetinae; Drinking; Eating; Female; Intubation, Gastrointestinal; Mesocricetus; Oligonucleotide Array Sequence Analysis; RNA; Solanine; Solanum tuberosum	2009
Fate of toxic potato glycoalkaloids in a potato field. Journal of agricultural and food chemistry, 2009, Apr-08, Volume: 57, Issue:7 Topics: Plant Leaves; Plant Stems; Plant Tubers; Seasons; Soil; Solanine; Solanum tuberosum; Water	2009
Probabilistic modelling of exposure doses and implications for health risk characterization: glycoalkaloids from potatoes. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2009, Volume: 47, Issue:12 Topics: Eating; Environmental Exposure; Europe; Humans; Models, Statistical; Solanine; Solanum tuberosum	2009
Degradation of the potato glycoalkaloids--alpha-solanine and alpha-chaconine in groundwater. Bulletin of environmental contamination and toxicology, 2009, Volume: 82, Issue:6 Topics: Bacteria; Biotransformation; Fungi; Solanine; Solanum tuberosum; Water Pollutants; Water Supply	2009
Glycoalkaloids as biomarkers for recognition of cultivated, wild, and somatic hybrids of potato. Chemistry & biodiversity, 2009, Volume: 6, Issue:4 Topics: Alkaloids; Biomarkers; Chromatography, High Pressure Liquid; Hybridization, Genetic; Plant Tubers; Solanine; Solanum tuberosum	2009
Degradation of the potato glycoalkaloid alpha-solanine in three agricultural soils. Chemosphere, 2009, Volume: 76, Issue:8 Topics: Agriculture; Biodegradation, Environmental; Half-Life; Kinetics; Plant Tubers; Soil; Solanine; Solanum tuberosum	2009
Composition of phenolic compounds and glycoalkaloids alpha-solanine and alpha-chaconine during commercial potato processing. Journal of agricultural and food chemistry, 2009, Jul-22, Volume: 57, Issue:14 Topics: Chlorogenic Acid; Chromatography, High Pressure Liquid; Food Handling; Food Preservation; Hot Temperature; Phenols; Solanine; Solanum tuberosum	2009
Elucidation of the mass fragmentation pathways of potato glycoalkaloids and aglycons using Orbitrap mass spectrometry. Journal of mass spectrometry : JMS, 2010, Volume: 45, Issue:9 Topics: Solanaceous Alkaloids; Solanine; Solanum tuberosum; Tandem Mass Spectrometry; Toxins, Biological	2010
α-Solanine inhibits human melanoma cell migration and invasion by reducing matrix metalloproteinase-2/9 activities. Biological & pharmaceutical bulletin, 2010, Volume: 33, Issue:10 Topics: Antineoplastic Agents, Phytogenic; Cell Movement; Cell Proliferation; Dose-Response Relationship, Drug; Humans; Matrix Metalloproteinases; Melanoma; Mitogen-Activated Protein Kinases; Neoplasm Invasiveness; NF-kappa B; Phosphorylation; Phytotherapy; Plant Extracts; Plant Shoots; Signal Transduction; Solanine; Solanum tuberosum	2010
Four potato (Solanum tuberosum) ABCG transporters and their expression in response to abiotic factors and Phytophthora infestans infection. Journal of plant physiology, 2011, Dec-15, Volume: 168, Issue:18 Topics: ATP-Binding Cassette Transporters; Chlorophenols; Gene Expression Regulation, Plant; Host-Pathogen Interactions; Phytophthora infestans; Plant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Sodium Chloride; Solanine; Solanum tuberosum	2011
Induction of potato steroidal glycoalkaloid biosynthetic pathway by overexpression of cDNA encoding primary metabolism HMG-CoA reductase and squalene synthase. Planta, 2012, Volume: 235, Issue:6 Topics: Alkaloids; Biosynthetic Pathways; Chromatography, High Pressure Liquid; DNA, Complementary; Farnesyl-Diphosphate Farnesyltransferase; Gene Expression Regulation, Plant; Genes, Plant; Hydroxymethylglutaryl CoA Reductases; Phytosterols; Plant Leaves; Plants, Genetically Modified; RNA, Messenger; Sequence Homology, Nucleic Acid; Solanine; Solanum tuberosum	2012
Glycoalkaloids (α-chaconine and α-solanine) contents of selected Pakistani potato cultivars and their dietary intake assessment. Journal of food science, 2012, Volume: 77, Issue:3 Topics: Chromatography, High Pressure Liquid; Food Handling; Food Safety; Humans; Pakistan; Reproducibility of Results; Solanine; Solanum tuberosum	2012
Compositional and toxicological analysis of a GM potato line with reduced α-solanine content--a 90-day feeding study in the Syrian Golden hamster. Regulatory toxicology and pharmacology : RTP, 2012, Volume: 64, Issue:1 Topics: Animal Feed; Animals; Blood Chemical Analysis; Consumer Product Safety; Cricetinae; Dose-Response Relationship, Drug; Female; Food, Genetically Modified; Freeze Drying; Hematologic Tests; Mesocricetus; Nutritive Value; Plants, Genetically Modified; Solanine; Solanum tuberosum; Toxicity Tests	2012
Preparative separation of glycoalkaloids α-solanine and α-chaconine by centrifugal partition chromatography. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2012, Nov-01, Volume: 908 Topics: Centrifugation; Chromatography, High Pressure Liquid; Organic Chemicals; Plant Extracts; Solanine; Solanum tuberosum; Water	2012
Guatemalan potato moth Tecia solanivora distinguish odour profiles from qualitatively different potatoes Solanum tuberosum L. Phytochemistry, 2013, Volume: 85 Topics: Animals; Female; Moths; Odorants; Oviposition; Phenols; Solanine; Solanum; Solanum tuberosum	2013
Anti-inflammatory properties of potato glycoalkaloids in stimulated Jurkat and Raw 264.7 mouse macrophages. Life sciences, 2013, Apr-19, Volume: 92, Issue:13 Topics: Animals; Anti-Inflammatory Agents; Cell Line; Concanavalin A; Diosgenin; Humans; Interleukin-2; Interleukin-8; Jurkat Cells; Lipopolysaccharides; Macrophages; Mice; Nitric Oxide; Plant Extracts; Solanine; Solanum tuberosum	2013
The influence of dietary α-solanine on the waxmoth Galleria mellonella L. Archives of insect biochemistry and physiology, 2013, Volume: 83, Issue:1 Topics: Animals; Fat Body; Female; Fertility; Gastrointestinal Tract; Glutathione Transferase; Male; Malondialdehyde; Moths; Oxidative Stress; Protein Carbonylation; Solanine	2013
Glycoalkaloid and calystegine levels in table potato cultivars subjected to wounding, light, and heat treatments. Journal of agricultural and food chemistry, 2013, Jun-19, Volume: 61, Issue:24 Topics: Crops, Agricultural; Food Handling; Food Quality; Glycosylation; Hot Temperature; Light; Mechanical Phenomena; Nortropanes; Plant Tubers; Solanaceous Alkaloids; Solanine; Solanum tuberosum; Species Specificity; Stereoisomerism; Sweden; Up-Regulation	2013
Synergistic cytotoxicity induced by α-solanine and α-chaconine. Food chemistry, 2013, Nov-15, Volume: 141, Issue:2 Topics: Animals; Biological Transport; Cell Line, Tumor; Cell Membrane; Cell Survival; NAD; Rats; Solanine; Solanum tuberosum; Toxins, Biological	2013
The protective and therapeutic effects of alpha-solanine on mice breast cancer. European journal of pharmacology, 2013, Oct-15, Volume: 718, Issue:1-3 Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Female; Humans; Mammary Neoplasms, Experimental; Mice; Neoplasm Metastasis; Neovascularization, Pathologic; Solanine	2013
Antitumor efficacy of α-solanine against pancreatic cancer in vitro and in vivo. PloS one, 2014, Volume: 9, Issue:2 Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Nude; Neoplasm Metastasis; Neoplasm Proteins; Neovascularization, Pathologic; Pancreatic Neoplasms; Solanine; Xenograft Model Antitumor Assays	2014
Effect of genotype and environment on the glycoalkaloid content of rare, heritage, and commercial potato varieties. Journal of food science, 2014, Volume: 79, Issue:5 Topics: Agriculture; Diet; Environment; Food Safety; Genotype; Humans; Plant Tubers; Solanine; Solanum tuberosum	2014
Detection of glycoalkaloids using disposable biosensors based on genetically modified enzymes. Analytical biochemistry, 2014, Jul-15, Volume: 457 Topics: Acetylcholinesterase; Biosensing Techniques; Butyrylcholinesterase; Disposable Equipment; Genetic Engineering; Solanine; Solanum tuberosum	2014
Potato leaf extract and its component, α-solanine, exert similar impacts on development and oxidative stress in Galleria mellonella L. Archives of insect biochemistry and physiology, 2014, Volume: 87, Issue:1 Topics: Animals; Antioxidants; Biomarkers; Fertility; Gastrointestinal Tract; Glutathione Transferase; Larva; Malondialdehyde; Moths; Oxidation-Reduction; Oxidative Stress; Plant Extracts; Plant Leaves; Solanine; Solanum tuberosum	2014
α-Solanine inhibits invasion of human prostate cancer cell by suppressing epithelial-mesenchymal transition and MMPs expression. Molecules (Basel, Switzerland), 2014, Aug-11, Volume: 19, Issue:8 Topics: Cadherins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Humans; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Prostatic Neoplasms; Signal Transduction; Solanine; Solanum nigrum; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2	2014
[Determination of alpha-solanine, alpha-chaconine and solanidine in plasma and urine by ultra-performance liquid chromatography-triple quadrupole mass spectrometry]. Se pu = Chinese journal of chromatography, 2014, Volume: 32, Issue:6 Topics: Chromatography, High Pressure Liquid; Diosgenin; Humans; Solanine; Solid Phase Extraction; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry	2014
Self-organizing behaviour of glycosteroidal bolaphiles: insights into lipidic microsegregation. Organic & biomolecular chemistry, 2015, Jan-21, Volume: 13, Issue:3 Topics: Biomimetic Materials; Calorimetry, Differential Scanning; Glycolipids; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Monosaccharides; Phase Transition; Quantum Theory; Solanine; Steroids; Temperature; Thermodynamics	2015
Recovery of steroidal alkaloids from potato peels using pressurized liquid extraction. Molecules (Basel, Switzerland), 2015, May-13, Volume: 20, Issue:5 Topics: Alkaloids; Diosgenin; Methanol; Phytochemicals; Solanaceous Alkaloids; Solanine; Solanum tuberosum; Solid Phase Extraction	2015
α-Solanine induces ROS-mediated autophagy through activation of endoplasmic reticulum stress and inhibition of Akt/mTOR pathway. Cell death & disease, 2015, Aug-27, Volume: 6 Topics: Activating Transcription Factor 4; Activating Transcription Factor 6; Adaptor Proteins, Signal Transducing; Antineoplastic Agents, Phytogenic; Apoptosis; Autophagy-Related Protein 8 Family; CCAAT-Enhancer-Binding Proteins; Cell Line, Tumor; Chloroquine; DNA-Binding Proteins; eIF-2 Kinase; Endoplasmic Reticulum Stress; Gene Expression Regulation, Neoplastic; Humans; Macrolides; Membrane Potential, Mitochondrial; Microfilament Proteins; Microtubule-Associated Proteins; Mitochondria; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Regulatory Factor X Transcription Factors; Signal Transduction; Solanine; TOR Serine-Threonine Kinases; Transcription Factors; Unfolded Protein Response	2015
Anticancer function of α-solanine in lung adenocarcinoma cells by inducing microRNA-138 expression. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2016, Volume: 37, Issue:5 Topics: 3' Untranslated Regions; Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Agents, Phytogenic; Base Sequence; Binding Sites; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drug Resistance, Neoplasm; Focal Adhesion Protein-Tyrosine Kinases; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; MicroRNAs; Radiation Tolerance; RNA Interference; Solanine	2016
α-Solanine inhibits vascular endothelial growth factor expression by down-regulating the ERK1/2-HIF-1α and STAT3 signaling pathways. European journal of pharmacology, 2016, Jan-15, Volume: 771 Topics: Cadherins; Cell Line, Tumor; Cobalt; Coculture Techniques; Down-Regulation; Humans; Hypoxia-Inducible Factor 1; MAP Kinase Signaling System; Pancreatic Neoplasms; Signal Transduction; Solanine; STAT3 Transcription Factor; Vascular Endothelial Growth Factor A	2016
Characterization and Transcriptional Profile of Genes Involved in Glycoalkaloid Biosynthesis in New Varieties of Solanum tuberosum L. Journal of agricultural and food chemistry, 2016, Feb-03, Volume: 64, Issue:4 Topics: Alkaloids; Biosynthetic Pathways; Plant Proteins; Plant Tubers; Promoter Regions, Genetic; Solanine; Solanum tuberosum; Transcription, Genetic	2016
Antifungal activity of secondary plant metabolites from potatoes (Solanum tuberosum L.): Glycoalkaloids and phenolic acids show synergistic effects. Journal of applied microbiology, 2016, Volume: 120, Issue:4 Topics: Antifungal Agents; Caffeic Acids; Diosgenin; Fungi; Microbial Sensitivity Tests; Phenols; Solanine; Solanum tuberosum	2016
Impact of light-exposure on the metabolite balance of transgenic potato tubers with modified glycoalkaloid biosynthesis. Food chemistry, 2016, Jun-01, Volume: 200 Topics: Chlorophyll; Chromatography, Liquid; Gas Chromatography-Mass Spectrometry; Light; Mass Spectrometry; Plant Tubers; Plants, Genetically Modified; Solanaceous Alkaloids; Solanine; Solanum tuberosum	2016
α-Solanine Isolated From Solanum Tuberosum L. cv Jayoung Abrogates LPS-Induced Inflammatory Responses Via NF-κB Inactivation in RAW 264.7 Macrophages and Endotoxin-Induced Shock Model in Mice. Journal of cellular biochemistry, 2016, Volume: 117, Issue:10 Topics: Animals; Apoptosis; Blotting, Western; Cell Proliferation; Cells, Cultured; Colitis; Cytokines; Disease Models, Animal; Inflammation; Inflammation Mediators; Lipopolysaccharides; Macrophages; Male; Mice; Mice, Inbred C57BL; NF-kappa B; Nitric Oxide; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Shock, Septic; Signal Transduction; Solanine; Solanum tuberosum	2016
Effect of Drying Methods on the Steroidal Alkaloid Content of Potato Peels, Shoots and Berries. Molecules (Basel, Switzerland), 2016, Mar-25, Volume: 21, Issue:4 Topics: Alkaloids; Chromatography, High Pressure Liquid; Freeze Drying; Fruit; Phytosterols; Plant Shoots; Solanine; Solanum tuberosum; Tandem Mass Spectrometry	2016
Solanum tuberosum and Lycopersicon esculentum Leaf Extracts and Single Metabolites Affect Development and Reproduction of Drosophila melanogaster. PloS one, 2016, Volume: 11, Issue:5 Topics: Animals; Body Size; Drosophila melanogaster; Female; Male; Pest Control, Biological; Plant Extracts; Plant Leaves; Reproduction; Solanine; Solanum lycopersicum; Solanum tuberosum; Tomatine	2016
Two Cytochrome P450 Monooxygenases Catalyze Early Hydroxylation Steps in the Potato Steroid Glycoalkaloid Biosynthetic Pathway. Plant physiology, 2016, Volume: 171, Issue:4 Topics: Biosynthetic Pathways; Breeding; Crops, Agricultural; Cytochrome P-450 Enzyme System; Gene Silencing; Hydroxylation; Phenotype; Phytosterols; Plant Proteins; Plant Tubers; Solanine; Solanum tuberosum	2016
α-Solanine Modulates the Radiosensitivity of Esophageal Cancer Cells by Inducing MicroRNA 138 Expression. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2016, Volume: 39, Issue:3 Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Base Sequence; Binding Sites; Cell Count; Cell Line, Tumor; Cell Proliferation; Cell Survival; Comet Assay; Dose-Response Relationship, Drug; Epithelial Cells; Esophagus; Gamma Rays; Gene Expression Regulation, Neoplastic; Humans; Inhibitor of Apoptosis Proteins; MicroRNAs; Radiation Tolerance; Radiation-Sensitizing Agents; Signal Transduction; Solanine; Survivin	2016
The Impact of Steroidal Glycoalkaloids on the Physiology of Phytophthora infestans, the Causative Agent of Potato Late Blight. Molecular plant-microbe interactions : MPMI, 2017, Volume: 30, Issue:7 Topics: Carbohydrate Sequence; Diosgenin; Fungal Proteins; Glycoside Hydrolases; Glycosylation; Host-Pathogen Interactions; Molecular Structure; Mycelium; Phytophthora infestans; Plant Diseases; Solanaceous Alkaloids; Solanine; Solanum lycopersicum; Solanum tuberosum; Steroids	2017
α-Solanine reverses pulmonary vascular remodeling and vascular angiogenesis in experimental pulmonary artery hypertension. Journal of hypertension, 2017, Volume: 35, Issue:12 Topics: Animals; Cells, Cultured; Humans; Hypertension, Pulmonary; Mice; Neovascularization, Pathologic; Pulmonary Artery; Solanine; Vascular Remodeling	2017
α-Solanine as potential therapeutic target in pulmonary artery hypertension. Journal of hypertension, 2017, Volume: 35, Issue:12 Topics: Humans; Hypertension; Pulmonary Artery; Solanine; Vascular Remodeling	2017
α-Solanine impairs oocyte maturation and quality by inducing autophagy and apoptosis and changing histone modifications in a pig model. Reproductive toxicology (Elmsford, N.Y.), 2018, Volume: 75 Topics: Animals; Apoptosis; Autophagy; Cell Survival; Cells, Cultured; Gene Expression; Histone Code; Membrane Potential, Mitochondrial; Oocytes; Solanine; Spindle Apparatus; Swine	2018
α-solanine enhances the chemosensitivity of esophageal cancer cells by inducing microRNA‑138 expression. Oncology reports, 2018, Volume: 39, Issue:3 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Cisplatin; Drug Resistance, Neoplasm; Esophageal Neoplasms; Female; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Inhibitor of Apoptosis Proteins; Mice; Mice, Inbred BALB C; Mice, Nude; MicroRNAs; Solanine; Survivin	2018
The effect of α-solanine on the activity, gene expression, and kinetics of arylamine N-acetyltransferase in HepG2 cells. Oncology reports, 2018, Volume: 39, Issue:5 Topics: Arylamine N-Acetyltransferase; Chromatography, High Pressure Liquid; Down-Regulation; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Isoenzymes; Solanine	2018
Anti-Cancer Effect of α-Solanine by Down-Regulating S100P Expression in Colorectal Cancer Cells. Recent patents on anti-cancer drug discovery, 2018, Volume: 13, Issue:2 Topics: Animals; Antineoplastic Agents; Calcium-Binding Proteins; Cell Line, Tumor; Colorectal Neoplasms; Down-Regulation; Gene Expression Regulation, Neoplastic; HT29 Cells; Humans; Mice; Mice, Nude; Neoplasm Proteins; Solanine; Treatment Outcome; Tumor Burden; Xenograft Model Antitumor Assays	2018
Generation of α-solanine-free hairy roots of potato by CRISPR/Cas9 mediated genome editing of the St16DOX gene. Plant physiology and biochemistry : PPB, 2018, Volume: 131 Topics: CRISPR-Cas Systems; Gene Editing; Gene Knockout Techniques; Genes, Plant; Plant Roots; Plants, Genetically Modified; Sequence Analysis, DNA; Solanine; Solanum tuberosum; Steroid 16-alpha-Hydroxylase	2018
α-Chaconine and α-Solanine Inhibit RL95-2 Endometrium Cancer Cell Proliferation by Reducing Expression of Akt (Ser473) and ERα (Ser167). Nutrients, 2018, May-25, Volume: 10, Issue:6 Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Down-Regulation; Endometrial Neoplasms; Estrogen Receptor alpha; Female; Humans; Inhibitory Concentration 50; Phosphorylation; Proto-Oncogene Proteins c-akt; Signal Transduction; Solanine; Time Factors	2018
Synthesis and insecticidal activities of novel solanidine derivatives. Pest management science, 2019, Volume: 75, Issue:3 Topics: Animals; Aphids; Diosgenin; Fertility; Insecticides; Nymph; Solanine; Solanum tuberosum	2019
Effect of citronella essential oil fumigation on sprout suppression and quality of potato tubers during storage. Food chemistry, 2019, Jun-30, Volume: 284 Topics: Cymbopogon; Food Storage; Fumigation; Germination; Gibberellins; Oils, Volatile; Plant Tubers; Solanine; Solanum tuberosum; Starch	2019
Organic-inorganic nanoparticles molecularly imprinted photoelectrochemical sensor for α-solanine based on p-type polymer dots and n-CdS heterojunction. Analytica chimica acta, 2019, Jun-20, Volume: 1059 Topics: Cadmium Compounds; Chitosan; Electrochemical Techniques; Limit of Detection; Models, Chemical; Molecular Imprinting; Photochemistry; Polymers; Quantum Dots; Reproducibility of Results; Solanine; Sulfides; Tin Compounds	2019
Long noncoding RNA GAS5 modulates α-Solanine-induced radiosensitivity by negatively regulating miR-18a in human prostate cancer cells. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019, Volume: 112 Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Gene Expression Regulation, Neoplastic; Humans; Male; MicroRNAs; Prostatic Neoplasms; Radiation Tolerance; Radiation-Sensitizing Agents; RNA, Long Noncoding; Solanine; X-Rays	2019
Alpha-solanine inhibits cell proliferation via mitochondrial dysfunction and inhibin synthesis in mouse testis In vitro and In vivo. Chemosphere, 2019, Volume: 235 Topics: Animals; Cell Proliferation; Cells, Cultured; Gene Expression Regulation; In Vitro Techniques; Inhibins; Leydig Cells; Male; Membrane Potential, Mitochondrial; Mice; Mice, Inbred C57BL; Mitochondria; Signal Transduction; Solanine; Spermatogenesis; Testis	2019
Synergistic Effect of α-Solanine and Cisplatin Induces Apoptosis and Enhances Cell Cycle Arrest in Human Hepatocellular Carcinoma Cells. Anti-cancer agents in medicinal chemistry, 2019, Volume: 19, Issue:18 Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Cell Cycle Checkpoints; Cell Proliferation; Cisplatin; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Hep G2 Cells; Humans; Liver Neoplasms; Solanine; Structure-Activity Relationship; Tumor Cells, Cultured	2019
RNA Sequencing Reveals That Both Abiotic and Biotic Stress-Responsive Genes are Induced during Expression of Steroidal Glycoalkaloid in Potato Tuber Subjected to Light Exposure. Genes, 2019, 11-11, Volume: 10, Issue:11 Topics: Disease Resistance; Exome Sequencing; Gene Expression Regulation, Plant; Light; Plant Tubers; RNA-Seq; Secondary Metabolism; Solanine; Solanum tuberosum; Stress, Physiological; Transcriptome	2019
Discovery of a Bacterial Gene Cluster for Deglycosylation of Toxic Potato Steroidal Glycoalkaloids α-Chaconine and α-Solanine. Journal of agricultural and food chemistry, 2020, Feb-05, Volume: 68, Issue:5 Topics: Arthrobacter; Bacterial Proteins; Biotransformation; Glycosylation; Multigene Family; Phylogeny; Solanine; Solanum tuberosum	2020
α‑Solanine inhibits growth and metastatic potential of human colorectal cancer cells. Oncology reports, 2020, Volume: 43, Issue:5 Topics: Animals; Antineoplastic Agents; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colorectal Neoplasms; Cyclin D1; Cyclin-Dependent Kinase 2; Dose-Response Relationship, Drug; Down-Regulation; Gene Expression Regulation, Neoplastic; HCT116 Cells; Humans; Male; Mice; Neoplasm Metastasis; Solanine; Time Factors; Xenograft Model Antitumor Assays	2020
Glyphosate-based herbicide has soil-mediated effects on potato glycoalkaloids and oxidative status of a potato pest. Chemosphere, 2020, Volume: 258 Topics: Animals; Antioxidants; Coleoptera; Glutathione Transferase; Glycine; Glyphosate; Herbicides; Larva; Oxidation-Reduction; Oxidative Stress; Soil; Solanine; Solanum tuberosum	2020
α-Solanine Causes Cellular Dysfunction of Human Trophoblast Cells via Apoptosis and Autophagy. Toxins, 2021, 01-18, Volume: 13, Issue:1 Topics: Apoptosis; Autophagy; Biomarkers; Cell Cycle Checkpoints; Cell Line; Cell Movement; Cell Proliferation; Cell Survival; Female; Humans; Pregnancy; Solanine; Trophoblasts	2021
The biosynthetic pathway of potato solanidanes diverged from that of spirosolanes due to evolution of a dioxygenase. Nature communications, 2021, 02-26, Volume: 12, Issue:1 Topics: Amino Acid Sequence; Biosynthetic Pathways; Cholesterol; Dioxygenases; Gene Expression Regulation, Plant; Genes, Plant; Hydroxylation; Ketoglutaric Acids; Phylogeny; Plants, Genetically Modified; Secondary Metabolism; Solanine; Solanum lycopersicum; Solanum melongena; Solanum tuberosum; Tomatine	2021
α-Solanine Inhibits Proliferation, Invasion, and Migration, and Induces Apoptosis in Human Choriocarcinoma JEG-3 Cells In Vitro and In Vivo. Toxins, 2021, 03-13, Volume: 13, Issue:3 Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Choriocarcinoma; Female; Humans; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Pregnancy; Signal Transduction; Solanine; Tumor Burden; Uterine Neoplasms; Xenograft Model Antitumor Assays	2021
Characterization of C-26 aminotransferase, indispensable for steroidal glycoalkaloid biosynthesis. The Plant journal : for cell and molecular biology, 2021, Volume: 108, Issue:1 Topics: 4-Aminobutyrate Transaminase; Gene Editing; Hydroxylation; Ketocholesterols; Plant Proteins; Plant Tubers; Saponins; Solanine; Solanum tuberosum	2021
Maleic and L-tartaric acids as new anti-sprouting agents for potatoes during storage in comparison to other efficient sprout suppressants. Scientific reports, 2021, 10-08, Volume: 11, Issue:1 Topics: Food Storage; Maleates; Plant Tubers; Solanine; Solanum tuberosum; Tartrates	2021
Involvement of miRNAs in response to oxidative stress induced by the steroidal glycoalkaloid α-solanine in hepatocellular carcinoma cells. Environmental toxicology, 2022, Volume: 37, Issue:2 Topics: Apoptosis; Carcinoma, Hepatocellular; Hep G2 Cells; Humans; Liver Neoplasms; MicroRNAs; NF-kappa B; Oxidative Stress; Solanine	2022
Alpha-solanine Anti-tumor Effects in Non-small Cell Lung Cancer Through Regulating the Energy Metabolism Pathway. Recent patents on anti-cancer drug discovery, 2022, Volume: 17, Issue:4 Topics: Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Energy Metabolism; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Patents as Topic; Solanine	2022
Solanaceae glycoalkaloids: α-solanine and α-chaconine modify the cardioinhibitory activity of verapamil. Pharmaceutical biology, 2022, Volume: 60, Issue:1 Topics: Solanaceae; Solanine; Solanum tuberosum; Verapamil	2022
Antioxidants Amelioration Is Insufficient to Prevent Acrylamide and Alpha-Solanine Synergistic Toxicity in BEAS-2B Cells. International journal of molecular sciences, 2023, Jul-26, Volume: 24, Issue:15 Topics: Acrylamide; Antioxidants; Butylated Hydroxyanisole; Butylated Hydroxytoluene; DNA; Proteins; RNA; Solanine	2023