solanine has been researched along with alpha-chaconine in 109 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 14 (12.84) | 18.7374 |
1990's | 19 (17.43) | 18.2507 |
2000's | 41 (37.61) | 29.6817 |
2010's | 29 (26.61) | 24.3611 |
2020's | 6 (5.50) | 2.80 |
Authors | Studies |
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Alozie, SO; Salunkhe, DK; Sharma, RP | 1 |
Nishie, K; Norred, WP; Swain, AP | 1 |
Hollingworth, RM; Wierenga, JM | 1 |
de Kruijff, B; de Vrije, T; Demel, RA; Fabrie, CH; Jongen, WM; Keukens, EA | 1 |
Friedman, M; Henika, PR | 1 |
Gabrielsson, J; Hellenäs, KE; Lööf, L; Nyman, A; Slanina, P | 1 |
Bergman, K; Cekan, E; Hellenäs, KE; Slanina, P | 1 |
Caldwell, KA; Friedman, M; Grosjean, OK; Henika, PR | 1 |
Bantle, JA; Friedman, M; Rayburn, JR | 2 |
de Kanel, J; Dunlap, L; Hall, TD | 1 |
Clarke, GF; Skuce, R; Thorne, HV | 1 |
Claringbold, WD; Earthy, ME; Few, JD; McLean, AC; Renwick, JH | 1 |
Bourcier, DR; Sharma, RP; Taylor, MJ | 1 |
Maga, JA | 1 |
Jadhav, SJ; Salunkhe, DK; Sharma, RP | 1 |
Bushway, RJ | 1 |
Hopkins, J | 1 |
Crawford, L; Myhr, B | 1 |
Wang, XG | 1 |
Chupin, V; de Kruijff, B; de Vrije, T; de Waard, P; Jongen, WM; Keukens, EA; Plasman, HH; Thiel, F; van den Boom, C | 1 |
Friedman, M; Henika, PR; Mackey, BE | 1 |
Anderson, D; Hughes, JA; Phillips, BJ; Phillips, JC; Tahourdin, CS; Walters, DG | 1 |
Bantle, JA; Friedman, M; Qualls, CW; Rayburn, JR | 1 |
Fukuhara, K; Kubo, I | 1 |
Brown, S; Cornell, JA; Graham, EM; Nigg, HN; Ramos, LE; Sterling, J | 1 |
Leonard, AL; Roddick, JG | 1 |
Brown, MS; Friedman, M; McDonald, GM | 1 |
Serrano, B; Sotelo, A | 1 |
Fung, DL; Gronert, GA; Krasowski, MD; McGehee, DS; Moss, J; Wilson, B | 1 |
Blankemeyer, JT; Friedman, M; McWilliams, ML | 1 |
Friedman, M; Kozukue, N; Tsuchida, H | 1 |
Driedger, DR; Sporns, P | 1 |
Jones, JL; Roddick, JG; Smith, DB | 1 |
Goethals, G; Grand, E; Lequart, V; Martin, P; Morillo, M; Usubillaga, A; Villa, P | 1 |
Tibbitts, TW; Wheeler, RM | 1 |
Charette, AB; Grenon, M; Lemire, A; Martel, J; Pourashraf, M | 1 |
Cardi, T; Carputo, D; Esposito, F; Filippone, E; Fogliano, V | 1 |
Doyle, J; Fedorak, RN; Jewel, L; Patel, B; Schutte, R; Sporns, P | 1 |
Kepczyński, J; Prescha, A; Szopa, J; Zuk, M | 1 |
Bodart, P; Noirfalise, A | 1 |
Friedman, M; Kozukue, N; Roitman, JN | 1 |
HOESS, HG; SCHIEDT, U | 1 |
DEPASQUALE, A | 1 |
de BOER, J | 1 |
El'skaya, AV; Jaffrezic-Renault, N; Korpan, YI; Martelet, C; Nazarenko, EA; Skryshevskaya, IV | 1 |
Baek, EJ; Chang, EY; Chang, JS; Friedman, M; Han, JS; Kozukue, N; Lee, KR; Park, JH | 1 |
Armer, CA | 1 |
Backleh, M; Coelhan, M; Ekici, P; Leupold, G; Parlar, H | 1 |
JOHNSON, CC; JOHNSON, G; POE, CF | 1 |
Anttila, K; Hartikainen, H; Ollilainen, V; Seppänen, M; Turakainen, M; Väänänen, T | 1 |
Bunch, TD; Evans, RC; Gaffield, W; Panter, KE; Wang, S | 1 |
Mensinga, TT; Meulenbelt, J; Rompelberg, CJ; Sips, AJ; van den Top, HJ; van Egmond, HP; van Twillert, K | 1 |
Kan, K; Saito, K; Shindo, T; Ushiyama, H; Yasuda, K | 1 |
Friedman, M; Kim, HJ; Kozukue, N; Lee, IS; Lee, KR | 1 |
Kim, JA; Kozukue, N; Lee, KR; Paek, SH; Yang, SA | 1 |
Friedman, M | 2 |
Gibson, DM; Krasnoff, SB; Loria, R; Wach, MJ | 1 |
Baykus, H; Garza, C; Kuiper, H; Mandimika, T; Peijnenburg, A; Poortman, J | 2 |
Hirokado, M; Kamata, K; Kan, K; Saito, K; Shimoi, T; Ushiyama, H | 1 |
Fogelman, E; Ginzberg, I; Krits, P | 1 |
Baykus, H; Garza, C; Jeurink, P; Kuiper, H; Mandimika, T; Peijnenburg, A; Poortman, J; Vissers, Y | 1 |
Chen, PS; Jeng, YF; Shih, YW; Wang, CJ; Wu, CH | 1 |
Hansen, HC; Hansen, TH; Jacobsen, OS; Jensen, PH; Juhler, RK; Nielsen, J; Nielsen, NJ; Strobel, BW | 1 |
Christiansen, J; Kirk, HG; Labouriau, R; Olsson, K; Sørensen, KK | 1 |
Dinkins, CL; Peterson, RK | 1 |
Conner, S; Davies, H; Langkilde, S; Meyer, O; Poulsen, M; Schrøder, M; Stewart, D | 1 |
Langkilde, S; Mandimika, T; Meyer, O; Peijnenburg, A; Poulsen, M; Schrøder, M; Slob, W | 1 |
Hansen, HC; Jacobsen, OS; Jensen, PH; Strobel, BW | 1 |
Boon, PE; Bosgra, S; Busk, L; Moussavian, S; Rehurkova, I; Ruprich, J; Svensson, K; Van der Voet, H; Van Klaveren, JD | 1 |
Hansen, HC; Henriksen, T; Jacobsen, OS; Jensen, PH; Strobel, BW | 1 |
Andolfi, A; Carputo, D; Cimmino, A; Evidente, A; Frusciante, L; Savarese, S | 1 |
Kroh, LW; Mäder, J; Rawel, H | 1 |
Churchill, T; Driedger, D; Fedorak, RN; Foshaug, R; Iablokov, V; Meddings, J; Sydora, BC | 1 |
Chang, YT; Chen, PH; Chen, PS; Huang, ET; Liu, CR; Lu, MK; Shih, YW | 1 |
Miller, JC; Reddivari, L; Safe, SH; Vanamala, J | 1 |
Cahill, MG; Caprioli, G; James, KJ; Vittori, S | 1 |
Demirel, U; Fogelman, E; Ginzberg, I; Mweetwa, AM; Thippeswamy, M; Tokuhisa, J; Veilleux, RE | 1 |
Asghar, A; Aziz, A; Butt, MS; Randhawa, MA; Shibamoto, T; Yasin, M | 1 |
Belknap, WR; Conner, S; Danier, J; Davies, HV; Engel, KH; Frank, T; Knudsen, I; Langkilde, S; McCue, KF; Meyer, O; Poulsen, M; Rychlik, M; Schrøder, M; Shepherd, LV; Stewart, D | 1 |
Deusser, H; Evers, D; Guignard, C; Hoffmann, L | 1 |
Attoumbré, J; Baltora-Rosset, S; Giordanengo, P; Lesur, D | 1 |
Brunton, NP; Collins, SG; Hossain, MB; Jones, PW; Kenny, OM; Maguire, AR; McCarthy, CM; O'Brien, NM; Rai, DK | 1 |
Andersson, HC; Arif, U; Hajšlová, J; Jonsson, L; Krtková, V; Meijer, J; Petersson, EV; Schulzova, V; Sitbon, F | 1 |
Matsuda, T; Yamashoji, S | 1 |
Gaffney, M; O'Brien, N; Reilly, K; Valcarcel, J | 1 |
Chira, A; Espinoza, MA; Istamboulie, G; Marty, JL; Noguer, T; Stoytcheva, M | 1 |
Cai, X; Zhang, X | 1 |
An, HJ; Jang, DS; Kim, NJ; Lee, HH; Lee, HJ; Lee, KG; Lee, KT; Lee, SG; Nam, JH; Shin, JS | 1 |
Aguiló-Aguayo, I; Brunton, NP; Hossain, MB; Rai, DK; Rawson, A | 1 |
de Oliveira, LA; Frazzon, J; Hutten, RC; Kok, EJ; Mariot, RF; Staats, M; van Dijk, JP; Voorhuijzen, MM | 1 |
Gänzle, MG; Sánchez-Maldonado, AF; Schieber, A | 1 |
Alexander, CJ; Belknap, WR; Davies, HV; Hackett, CA; McCue, KF; McNicol, JW; McRae, D; Shepherd, LV; Sungurtas, JA | 1 |
Brunton, NP; Hossain, MB; Rai, DK | 1 |
Adamski, Z; Bufo, SA; Büyükgüzel, E; Büyükgüzel, K; Chudzińska, E; Erdem, M; Falabella, P; Marciniak, P; Miądowicz-Kobielska, M; Scrano, L; Ventrella, E | 1 |
Mizutani, M; Muranaka, T; Nakayasu, M; Ohyama, K; Saito, K; Seki, H; Umemoto, N; Yotsu-Yamashita, M | 1 |
Combes, D; Due, AE; Koffi, GY; Remaud-Simeon, M | 1 |
Bulone, V; Dahlin, P; Ekengren, S; McKee, LS; Müller, MC | 1 |
Karaboğa Arslan, AK; Yerer, MB | 1 |
Ameline, A; Attoumbré, J; Beaulieu, R; Chesnais, Q; Giordanengo, P; Gobert, V; Grand, E; Kovensky, J; Stasik, I | 1 |
Chen, Z; Kang, Y; Qin, S; Zhang, W; Zuo, C | 1 |
Greve-Poulsen, M; Hennessy, RC; Larsen, LB; Nielsen, SD; Stougaard, P; Sørensen, OB | 1 |
Helander, M; Lindström, L; Margus, A; Rainio, MJ; Saikkonen, K; Salminen, JP; Virtanen, V | 1 |
Akiyama, R; Kato, J; Lee, HJ; Mizutani, M; Muranaka, T; Nakayasu, M; Saito, K; Sugimoto, Y; Umemoto, N; Watanabe, B | 1 |
Akiyama, R; Lee, HJ; Miyachi, H; Mizutani, M; Muranaka, T; Nakayasu, M; Ohyama, K; Saito, K; Sugimoto, Y; Umemoto, N; Watanabe, B | 1 |
Bhattacharya, E; Mandal Biswas, S; Pramanik, P | 1 |
Adamski, Z; Bufo, SA; Chowański, S; Mańczak, D; Marciniak, P; Scrano, L; Spochacz, M; Szymczak-Cendlak, M; Walkowiak-Nowicka, K; Winkiel, M | 1 |
7 review(s) available for solanine and alpha-chaconine
Article | Year |
---|---|
Potato glycoalkaloids.
Topics: Diosgenin; Food Preservation; Models, Biological; Plants, Edible; Solanaceous Alkaloids; Solanine; Species Specificity; Vegetables | 1980 |
Naturally occurring toxic alkaloids in foods.
Topics: Alkaloids; Animals; Chemical Phenomena; Chemistry; Humans; Light; Solanaceous Alkaloids; Solanine; Tomatine; Vegetables | 1981 |
The glycoalkaloids: naturally of interest (but a hot potato?).
Topics: Animals; Congenital Abnormalities; Female; Foodborne Diseases; Humans; Male; Mutagenicity Tests; Mutation; Pregnancy; Reproduction; Solanine; Solanum tuberosum; United Kingdom | 1995 |
Steroidal glycoalkaloids in Andean potatoes.
Topics: Bolivia; Chromatography; Chromatography, High Pressure Liquid; Glycosides; Solanine; Solanum tuberosum; Steroids | 1996 |
Potato glycoalkaloids: true safety or false sense of security?
Topics: Abnormalities, Drug-Induced; Animals; Cell Division; Cell Line, Tumor; Cell Physiological Phenomena; DNA Damage; Humans; Plant Poisoning; Solanaceous Alkaloids; Solanine; Solanum tuberosum; Viruses | 2004 |
Potato glycoalkaloids and metabolites: roles in the plant and in the diet.
Topics: Animals; Carbohydrate Sequence; Diet; Glycosides; Humans; Molecular Sequence Data; Plant Physiological Phenomena; Solanaceous Alkaloids; Solanine; Solanum tuberosum | 2006 |
Chemistry and anticarcinogenic mechanisms of glycoalkaloids produced by eggplants, potatoes, and tomatoes.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Cell Line, Tumor; Humans; Mice; Solanaceous Alkaloids; Solanine; Solanum lycopersicum; Solanum melongena; Solanum tuberosum; Structure-Activity Relationship; Tomatine | 2015 |
1 trial(s) available for solanine and alpha-chaconine
Article | Year |
---|---|
Potato glycoalkaloids and adverse effects in humans: an ascending dose study.
Topics: Adult; Area Under Curve; Biological Availability; Dose-Response Relationship, Drug; Female; Half-Life; Humans; Male; Middle Aged; Solanine; Solanum tuberosum | 2005 |
101 other study(ies) available for solanine and alpha-chaconine
Article | Year |
---|---|
Excretion of alpha-chaconine-3H, a steroidal glycoalkaloid from Solanum tuberosum L. and its metabolites in hamsters.
Topics: Animals; Cricetinae; Feces; Mesocricetus; Solanine; Time Factors | 1979 |
Pharmacology and toxicology of chaconine and tomatine.
Topics: Abnormalities, Drug-Induced; Alkaloids; Animals; Anura; Birth Weight; Blood Pressure; Chick Embryo; Chickens; Electroencephalography; Glycosides; Guinea Pigs; Heart Rate; Ileum; In Vitro Techniques; Lethal Dose 50; Male; Mice; Muscle Contraction; Muscle, Smooth; Rabbits; Solanine; Species Specificity; Teratogens; Time Factors; Tomatine | 1975 |
Inhibition of insect acetylcholinesterase by the potato glycoalkaloid alpha-chaconine.
Topics: Adaptation, Physiological; Animals; Cholinesterase Inhibitors; Insecta; Insecticide Resistance; Solanine; Solanum tuberosum; Species Specificity | 1992 |
Dual specificity of sterol-mediated glycoalkaloid induced membrane disruption.
Topics: Calorimetry, Differential Scanning; Carbohydrate Sequence; Cell Membrane; Diosgenin; Freeze Fracturing; Lipid Bilayers; Microscopy, Electron; Molecular Sequence Data; Solanaceous Alkaloids; Solanine; Sterols; Substrate Specificity; Tomatine | 1992 |
Absence of genotoxicity of potato alkaloids alpha-chaconine, alpha-solanine and solanidine in the Ames Salmonella and adult and foetal erythrocyte micronucleus assays.
Topics: Animals; Diosgenin; Female; Fetus; Injections, Intraperitoneal; Male; Mice; Micronucleus Tests; Mortality; Mutagenicity Tests; Mutagens; Salmonella typhimurium; Solanaceous Alkaloids; Solanine; Solanum tuberosum | 1992 |
Determination of potato glycoalkaloids and their aglycone in blood serum by high-performance liquid chromatography. Application to pharmacokinetic studies in humans.
Topics: Adult; Alkaloids; Chromatography, High Pressure Liquid; Diosgenin; Half-Life; Humans; Male; Solanaceous Alkaloids; Solanine; Solanum tuberosum; Spectrophotometry, Ultraviolet | 1992 |
Studies of embryotoxicity and the incidence of external malformations after continuous intravenous infusion of alpha-chaconine in pregnant rats.
Topics: Animals; Female; Incidence; Infusions, Intravenous; Pregnancy; Rats; Rats, Inbred Strains; Solanine; Teratogens | 1992 |
Hepatic ornithine decarboxylase induction by potato glycoalkaloids in rats.
Topics: Animals; Diosgenin; Enzyme Induction; Injections, Intraperitoneal; Liver; Male; Ornithine Decarboxylase; Rats; Rats, Inbred Strains; Solanaceous Alkaloids; Solanine; Solanum tuberosum | 1991 |
Developmental toxicology of potato alkaloids in the frog embryo teratogenesis assay--Xenopus (FETAX).
Topics: Abnormalities, Drug-Induced; Animals; Diosgenin; Embryo, Nonmammalian; Lethal Dose 50; Microsomes, Liver; Rats; Solanaceous Alkaloids; Solanine; Solanum tuberosum; Teratogens; Xenopus | 1991 |
Extending the detection limit of the TDx fluorescence polarization immunoassay for benzoylecgonine in urine.
Topics: Autoanalysis; Cocaine; False Negative Reactions; Fluorescence Polarization; Humans; Immunoassay; Mathematics; Solanine; Statistics as Topic; Substance-Related Disorders | 1989 |
The inactivation of herpes simplex virus by some Solanaceae glycoalkaloids.
Topics: Animals; Cell Line; Cell Membrane; Cell Survival; Chlorocebus aethiops; Diosgenin; Erythrocyte Membrane; Monosaccharides; Sheep; Simplexvirus; Solanaceous Alkaloids; Solanine; Structure-Activity Relationship; Tomatine | 1985 |
Neural-tube defects produced in Syrian hamsters by potato glycoalkaloids.
Topics: Abnormalities, Drug-Induced; Animals; Cricetinae; Dose-Response Relationship, Drug; Female; Humans; Male; Mesocricetus; Neural Tube Defects; Pregnancy; Sex Factors; Solanine; Vegetables | 1984 |
Subcellular distribution of alpha-chaconine in mouse hepatocytes.
Topics: Animals; Enzyme Induction; Female; Liver; Mice; Solanine | 1983 |
High-performance liquid chromatographic separation of potato glycoalkaloids using a radially compressed amino column.
Topics: Alkaloids; Chromatography, High Pressure Liquid; Solanine; Solvents; Vegetables | 1982 |
A preliminary assessment of the toxic and mutagenic potential of steroidal alkaloids in transgenic mice.
Topics: Alkaloids; Animals; Diosgenin; Embryonic and Fetal Development; Female; Gene Expression Regulation, Developmental; Lac Operon; Liver; Mice; Mice, Inbred BALB C; Mice, Transgenic; Mutation; Pregnancy; Solanaceous Alkaloids; Solanine; Solanum tuberosum; Teratogens; Tretinoin; Veratrum Alkaloids | 1995 |
[Teratogenic effect of potato glycoalkaloids].
Topics: Abnormalities, Drug-Induced; Animals; Female; Fetal Death; Fetal Growth Retardation; Lethal Dose 50; Mice; Neural Tube Defects; Pregnancy; Solanine; Solanum tuberosum | 1993 |
Molecular basis of glycoalkaloid induced membrane disruption.
Topics: Carbohydrate Sequence; Magnetic Resonance Spectroscopy; Membranes, Artificial; Microscopy, Electron; Models, Molecular; Molecular Sequence Data; Solanine; Sterols; Tomatine | 1995 |
Feeding of potato, tomato and eggplant alkaloids affects food consumption and body and liver weights in mice.
Topics: Alkaloids; Animals; Body Weight; Dehydroepiandrosterone; Diosgenin; Eating; Female; Liver; Mice; Organ Size; Plants, Edible; Solanaceous Alkaloids; Solanine; Solanum lycopersicum; Solanum tuberosum; Structure-Activity Relationship; Tomatine; Vegetables | 1996 |
A study of the toxic hazard that might be associated with the consumption of green potato tops.
Topics: Animals; Blood Cells; Cell Survival; CHO Cells; Chromatography, High Pressure Liquid; Cricetinae; Humans; Male; Mice; Plant Leaves; Rats; Rats, Sprague-Dawley; Solanine; Solanum tuberosum | 1996 |
Synergistic interaction of glycoalkaloids alpha-chaconine and alpha-solanine on developmental toxicity in Xenopus embryos.
Topics: Abnormalities, Drug-Induced; Animals; Drug Synergism; Embryo, Nonmammalian; Embryonic Development; Solanine; Survival Rate; Teratogens; Toxicity Tests; Xenopus | 1995 |
Protective effects of glucose-6-phosphate and NADP against alpha-chaconine-induced developmental toxicity in Xenopus embryos.
Topics: Animals; Biotransformation; Embryo, Nonmammalian; Embryonic Development; Glucose-6-Phosphate; Glucosephosphates; Male; Microsomes, Liver; NADP; Rats; Rats, Sprague-Dawley; Solanine; Teratogens; Toxicity Tests; Xenopus | 1995 |
Inhibition of human plasma and serum butyrylcholinesterase (EC 3.1.1.8) by alpha-chaconine and alpha-solanine.
Topics: Butyrylcholinesterase; Cholinesterase Inhibitors; Electrophoresis, Polyacrylamide Gel; Humans; Paraoxon; Solanine; Substrate Specificity | 1996 |
Amelioration by glucose-6-phosphate and NADP of potato glycoalkaloid inhibition in cell, enzyme and liposome assays.
Topics: Acetylcholinesterase; Cholinesterase Inhibitors; Glucose-6-Phosphate; Hemolysis; Humans; Liposomes; NADP; Solanine; Solanum tuberosum | 1999 |
Sampling leaves of young potato (Solanum tuberosum) plants for glycoalkaloid analysis.
Topics: Freeze Drying; Plant Leaves; Solanaceous Alkaloids; Solanine; Solanum tuberosum | 1999 |
High-performance liquid chromatographic determination of the glycoalkaloids alpha-solanine and alpha-chaconine in 12 commercial varieties of Mexican potato.
Topics: Chromatography, High Pressure Liquid; Humans; Mexico; Safety; Solanine; Solanum tuberosum; Species Specificity | 2000 |
Cholinesterase inhibition by potato glycoalkaloids slows mivacurium metabolism.
Topics: Animals; Cholinesterase Inhibitors; Drug Interactions; Female; Humans; Isoquinolines; Male; Mivacurium; Neuromuscular Nondepolarizing Agents; Rabbits; Solanine; Solanum tuberosum | 2000 |
The folic acid analogue methotrexate protects frog embryo cell membranes against damage by the potato glycoalkaloid alpha-chaconine.
Topics: Animals; Carbohydrate Sequence; Cell Membrane; Embryo, Nonmammalian; Folic Acid Antagonists; Methotrexate; Molecular Sequence Data; Neopterin; Solanine; Solanum tuberosum; Spectrometry, Fluorescence; Xenopus laevis | 2000 |
Tracer studies on the incorporation of [2-14C]-DL-mevalonate into chlorophylls a and b, alpha-chaconine, and alpha-solanine of potato sprouts.
Topics: Carbon Radioisotopes; Chlorophyll; Chlorophyll A; Chromatography, High Pressure Liquid; Mevalonic Acid; Solanine; Solanum tuberosum | 2001 |
Immunoaffinity sample purification and MALDI-TOF MS analysis of alpha-Solanine and alpha-chaconine in serum.
Topics: Animals; Antibodies; Chromatography, Affinity; Female; Rabbits; Sensitivity and Specificity; Solanine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2001 |
Synergism between the potato glycoalkaloids alpha-chaconine and alpha-solanine in inhibition of snail feeding.
Topics: Animals; Drug Synergism; Feeding Behavior; Helix, Snails; Solanine; Solanum tuberosum | 2001 |
Synthesis of peracetylated chacotriose.
Topics: Carbohydrate Conformation; Carbohydrate Sequence; Molecular Sequence Data; Peracetic Acid; Plant Extracts; Solanaceous Alkaloids; Solanine; Solanum tuberosum; Tropanes | 2001 |
Utilization of potatoes in bioregenerative life support systems.
Topics: Carbon Dioxide; Ecological Systems, Closed; Life Support Systems; Light; Lighting; Organ Size; Photons; Photoperiod; Plant Stems; Solanine; Solanum tuberosum; Temperature; Toxins, Biological | 1987 |
Practical and highly regio- and stereoselective synthesis of 2-substituted dihydropyridines and piperidines: application to the synthesis of (-)-coniine.
Topics: Dihydropyridines; Oxidation-Reduction; Piperidines; Solanine; Stereoisomerism; Substrate Specificity | 2001 |
Glycoalkaloid content and chemical composition of potatoes improved with nonconventional breeding approaches.
Topics: Chitinases; Food Technology; Genetic Engineering; Genotype; Plant Proteins; Plants, Genetically Modified; Solanine; Solanum tuberosum; Transfection | 2002 |
Potato glycoalkaloids adversely affect intestinal permeability and aggravate inflammatory bowel disease.
Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; In Vitro Techniques; Inflammatory Bowel Diseases; Intestinal Mucosa; Mice; Permeability; Solanaceous Alkaloids; Solanine; Solanum tuberosum; Time Factors | 2002 |
ADP ribosylation factor regulates metabolism and antioxidant capacity of transgenic potato tubers.
Topics: 14-3-3 Proteins; ADP-Ribosylation Factors; Amino Acids; Antioxidants; Carbohydrates; DNA, Antisense; Fatty Acids; Flavonoids; Gene Expression; Lipids; Phenotype; Plant Proteins; Plant Roots; Plants, Genetically Modified; Solanine; Solanum; Transformation, Genetic; Tyrosine 3-Monooxygenase | 2003 |
[Glycoalkaloids in potatoes].
Topics: Alkaloids; Molecular Structure; Solanine; Solanum tuberosum | 2003 |
Glycoalkaloid and calystegine contents of eight potato cultivars.
Topics: Chromatography, High Pressure Liquid; Freeze Drying; Gas Chromatography-Mass Spectrometry; Hydrogen-Ion Concentration; Nortropanes; Plant Extracts; Solanaceous Alkaloids; Solanine; Solanum tuberosum; Vegetables | 2003 |
[On the biogenesis of alkaloids. III. Lysine as the precursor to coniine].
Topics: Alkaloids; Humans; Lysine; Piperidines; Solanine | 1962 |
[SPECTROPHOROMETRIC DETERMINATION OF CONIINE].
Topics: Alkaloids; Hypertension; Hypertension, Renal; Piperidines; Research; Solanine; Spectrophotometry | 1963 |
The death of Socrates. A historical and experimental study on the actions of coniine and conium maculatum.
Topics: Alkaloids; Conium; Piperidines; Solanine | 1950 |
Glycoalkaloids and metabolites inhibit the growth of human colon (HT29) and liver (HepG2) cancer cells.
Topics: Alkaloids; Cell Division; Colonic Neoplasms; Humans; Hydrolysis; Liver Neoplasms; Solanine; Solanum; Solanum lycopersicum; Structure-Activity Relationship; Tomatine; Tumor Cells, Cultured | 2004 |
Colorado potato beetle toxins revisited: evidence the beetle does not sequester host plant glycoalkaloids.
Topics: Animals; Coleoptera; Feeding Behavior; Hemolymph; Oregon; Plant Leaves; Solanine; Solanum tuberosum | 2004 |
Enrichment of the glycoalkaloids alpha-solanine and alpha-chaconine from potato juice by adsorptive bubble separation using a pH gradient.
Topics: Alkaloids; Chromatography, High Pressure Liquid; Hydrogen-Ion Concentration; Plant Extracts; Solanine; Solanum tuberosum; Time Factors | 2004 |
Toxicity of alkaloids for certain bacteria; coniine, nicotine, and strychnine.
Topics: Alkaloids; Bacteria; Humans; Nicotine; Piperidines; Solanine; Strychnine | 1949 |
Effect of selenate supplementation on glycoalkaloid content of potato (Solanum tuberosum L.).
Topics: Alkaloids; Chromatography, High Pressure Liquid; Plant Tubers; Selenic Acid; Selenium Compounds; Solanine; Solanum tuberosum | 2004 |
Effects of steroidal glycoalkaloids from potatoes (Solanum tuberosum) on in vitro bovine embryo development.
Topics: Animals; Cattle; Diosgenin; Embryonic Development; Fertilization in Vitro; Solanaceous Alkaloids; Solanine; Solanum tuberosum; Tissue Culture Techniques | 2005 |
[Contents and its change during storage of alpha-solanine and alpha-chaconine in potatoes].
Topics: Chromatography, High Pressure Liquid; Food Preservation; Solanine; Solanum tuberosum | 2004 |
Anticarcinogenic effects of glycoalkaloids from potatoes against human cervical, liver, lymphoma, and stomach cancer cells.
Topics: Anticarcinogenic Agents; Antineoplastic Agents; Cell Death; Cell Line, Tumor; Diet; Drug Synergism; Female; Humans; Liver Neoplasms; Lymphoma; Neoplasms; Plant Tubers; Solanine; Solanum tuberosum; Stomach Neoplasms; Uterine Cervical Neoplasms | 2005 |
Alpha-chaconine, a potato glycoalkaloid, induces apoptosis of HT-29 human colon cancer cells through caspase-3 activation and inhibition of ERK 1/2 phosphorylation.
Topics: Apoptosis; Caspase 3; Caspases; Enzyme Activation; Enzyme Inhibitors; HT29 Cells; Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Solanine | 2006 |
Effect of carbohydrates on the production of thaxtomin A by Streptomyces acidiscabies.
Topics: Avena; Carbohydrates; Glucans; Indoles; Piperazines; Plant Extracts; Solanine; Streptomyces; Triticum; Xylans | 2007 |
Induction of the cholesterol biosynthesis pathway in differentiated Caco-2 cells by the potato glycoalkaloid alpha-chaconine.
Topics: Biomarkers; Caco-2 Cells; Cell Differentiation; Cholesterol; Cluster Analysis; Data Interpretation, Statistical; Dose-Response Relationship, Drug; Gene Expression; Gene Expression Profiling; Humans; L-Lactate Dehydrogenase; Oligonucleotide Array Sequence Analysis; Solanine; Solanum tuberosum; Up-Regulation | 2007 |
[Survey of glycoalkaloids content in the various potatoes].
Topics: Solanaceous Alkaloids; Solanine; Solanum tuberosum | 2007 |
Potato steroidal glycoalkaloid levels and the expression of key isoprenoid metabolic genes.
Topics: Gene Expression Regulation, Plant; Genes, Plant; Genotype; Models, Biological; Plant Leaves; Reverse Transcriptase Polymerase Chain Reaction; Solanaceous Alkaloids; Solanine; Solanum tuberosum; Terpenes | 2007 |
Differential gene expression in intestinal epithelial cells induced by single and mixtures of potato glycoalkaloids.
Topics: Apoptosis; Caco-2 Cells; Cell Cycle; Cholesterol; Dose-Response Relationship, Drug; Gene Expression; Gene Expression Profiling; Humans; Intestinal Mucosa; L-Lactate Dehydrogenase; Lipid Metabolism; Oligonucleotide Array Sequence Analysis; Proteins; Severity of Illness Index; Solanine; Solanum tuberosum | 2007 |
Alpha-chaconine-reduced metastasis involves a PI3K/Akt signaling pathway with downregulation of NF-kappaB in human lung adenocarcinoma A549 cells.
Topics: Antineoplastic Agents, Phytogenic; Cell Death; Cell Line, Tumor; DNA; Humans; Lung Neoplasms; Neoplasm Invasiveness; Neoplasm Metastasis; NF-kappa B; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Signal Transduction; Solanine | 2007 |
Potato glycoalkaloids in soil-optimising liquid chromatography-time-of-flight mass spectrometry for quantitative studies.
Topics: Chromatography, Liquid; Molecular Structure; Reproducibility of Results; Soil; Solanaceous Alkaloids; Solanine; Solanum tuberosum; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2008 |
A major QTL and an SSR marker associated with glycoalkaloid content in potato tubers from Solanum tuberosum x S. sparsipilum located on chromosome I.
Topics: Amplified Fragment Length Polymorphism Analysis; Breeding; Chromatography, High Pressure Liquid; Chromosome Mapping; Chromosomes, Plant; Diploidy; DNA, Plant; Genetic Linkage; Genetic Markers; Light; Phenotype; Plant Tubers; Polymerase Chain Reaction; Principal Component Analysis; Quantitative Trait Loci; Repetitive Sequences, Nucleic Acid; Solanine; Solanum tuberosum | 2008 |
A human dietary risk assessment associated with glycoalkaloid responses of potato to Colorado potato beetle defoliation.
Topics: Adolescent; Adult; Animals; Child; Child, Preschool; Coleoptera; Diet; Dose-Response Relationship, Drug; Eating; Female; Humans; Infant; Lethal Dose 50; Male; No-Observed-Adverse-Effect Level; Pregnancy; Risk Assessment; Solanine; Solanum tuberosum | 2008 |
Acute toxicity of high doses of the glycoalkaloids, alpha-solanine and alpha-chaconine, in the Syrian Golden hamster.
Topics: Acetylcholinesterase; Animals; Butyrylcholinesterase; Cricetinae; Dose-Response Relationship, Drug; Female; Intestine, Small; Mesocricetus; Solanine | 2008 |
PI3K/AKT, JNK, and ERK pathways are not crucial for the induction of cholesterol biosynthesis gene transcription in intestinal epithelial cells following treatment with the potato glycoalkaloid alpha-chaconine.
Topics: Caco-2 Cells; Cholesterol; Epithelial Cells; Extracellular Signal-Regulated MAP Kinases; Gene Expression; Humans; Intestinal Mucosa; JNK Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Solanine; Solanum tuberosum; Sterol Regulatory Element Binding Protein 2 | 2008 |
A 28-day repeat dose toxicity study of steroidal glycoalkaloids, alpha-solanine and alpha-chaconine in the Syrian Golden hamster.
Topics: Acetylcholinesterase; Animals; Biological Availability; Blood Cell Count; Blood Chemical Analysis; Body Weight; Butyrylcholinesterase; Cholinesterases; Cricetinae; Drinking; Eating; Female; Intubation, Gastrointestinal; Mesocricetus; Oligonucleotide Array Sequence Analysis; RNA; Solanine; Solanum tuberosum | 2009 |
Fate of toxic potato glycoalkaloids in a potato field.
Topics: Plant Leaves; Plant Stems; Plant Tubers; Seasons; Soil; Solanine; Solanum tuberosum; Water | 2009 |
Probabilistic modelling of exposure doses and implications for health risk characterization: glycoalkaloids from potatoes.
Topics: Eating; Environmental Exposure; Europe; Humans; Models, Statistical; Solanine; Solanum tuberosum | 2009 |
Degradation of the potato glycoalkaloids--alpha-solanine and alpha-chaconine in groundwater.
Topics: Bacteria; Biotransformation; Fungi; Solanine; Solanum tuberosum; Water Pollutants; Water Supply | 2009 |
Glycoalkaloids as biomarkers for recognition of cultivated, wild, and somatic hybrids of potato.
Topics: Alkaloids; Biomarkers; Chromatography, High Pressure Liquid; Hybridization, Genetic; Plant Tubers; Solanine; Solanum tuberosum | 2009 |
Composition of phenolic compounds and glycoalkaloids alpha-solanine and alpha-chaconine during commercial potato processing.
Topics: Chlorogenic Acid; Chromatography, High Pressure Liquid; Food Handling; Food Preservation; Hot Temperature; Phenols; Solanine; Solanum tuberosum | 2009 |
Naturally occurring glycoalkaloids in potatoes aggravate intestinal inflammation in two mouse models of inflammatory bowel disease.
Topics: Animals; Colitis, Ulcerative; Cooking; Crohn Disease; Cytokines; Dextran Sulfate; Disease Models, Animal; Genetic Predisposition to Disease; Inflammatory Bowel Diseases; Intestinal Mucosa; Mice; Peroxidase; Solanaceous Alkaloids; Solanine; Solanum tuberosum | 2010 |
alpha-Chaconine inhibits angiogenesis in vitro by reducing matrix metalloproteinase-2.
Topics: Angiogenesis Inhibitors; Animals; Cattle; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Endothelial Cells; Extracellular Signal-Regulated MAP Kinases; JNK Mitogen-Activated Protein Kinases; Matrix Metalloproteinase 2; Neovascularization, Pathologic; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphorylation; Plant Extracts; Proto-Oncogene Proteins c-akt; Seedlings; Solanine; Solanum tuberosum | 2010 |
The bioactive compounds alpha-chaconine and gallic acid in potato extracts decrease survival and induce apoptosis in LNCaP and PC3 prostate cancer cells.
Topics: Antigens, CD1; Apoptosis; Caspases; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p27; Extracellular Signal-Regulated MAP Kinases; Gallic Acid; Humans; Intracellular Signaling Peptides and Proteins; JNK Mitogen-Activated Protein Kinases; Male; Plant Extracts; Prostatic Neoplasms; Solanine; Solanum tuberosum | 2010 |
Elucidation of the mass fragmentation pathways of potato glycoalkaloids and aglycons using Orbitrap mass spectrometry.
Topics: Solanaceous Alkaloids; Solanine; Solanum tuberosum; Tandem Mass Spectrometry; Toxins, Biological | 2010 |
Induction of potato steroidal glycoalkaloid biosynthetic pathway by overexpression of cDNA encoding primary metabolism HMG-CoA reductase and squalene synthase.
Topics: Alkaloids; Biosynthetic Pathways; Chromatography, High Pressure Liquid; DNA, Complementary; Farnesyl-Diphosphate Farnesyltransferase; Gene Expression Regulation, Plant; Genes, Plant; Hydroxymethylglutaryl CoA Reductases; Phytosterols; Plant Leaves; Plants, Genetically Modified; RNA, Messenger; Sequence Homology, Nucleic Acid; Solanine; Solanum tuberosum | 2012 |
Glycoalkaloids (α-chaconine and α-solanine) contents of selected Pakistani potato cultivars and their dietary intake assessment.
Topics: Chromatography, High Pressure Liquid; Food Handling; Food Safety; Humans; Pakistan; Reproducibility of Results; Solanine; Solanum tuberosum | 2012 |
Compositional and toxicological analysis of a GM potato line with reduced α-solanine content--a 90-day feeding study in the Syrian Golden hamster.
Topics: Animal Feed; Animals; Blood Chemical Analysis; Consumer Product Safety; Cricetinae; Dose-Response Relationship, Drug; Female; Food, Genetically Modified; Freeze Drying; Hematologic Tests; Mesocricetus; Nutritive Value; Plants, Genetically Modified; Solanine; Solanum tuberosum; Toxicity Tests | 2012 |
Polyphenol and glycoalkaloid contents in potato cultivars grown in Luxembourg.
Topics: Chromatography, High Pressure Liquid; Luxembourg; Plant Extracts; Polyphenols; Solanine; Solanum tuberosum; Tandem Mass Spectrometry | 2012 |
Preparative separation of glycoalkaloids α-solanine and α-chaconine by centrifugal partition chromatography.
Topics: Centrifugation; Chromatography, High Pressure Liquid; Organic Chemicals; Plant Extracts; Solanine; Solanum tuberosum; Water | 2012 |
Anti-inflammatory properties of potato glycoalkaloids in stimulated Jurkat and Raw 264.7 mouse macrophages.
Topics: Animals; Anti-Inflammatory Agents; Cell Line; Concanavalin A; Diosgenin; Humans; Interleukin-2; Interleukin-8; Jurkat Cells; Lipopolysaccharides; Macrophages; Mice; Nitric Oxide; Plant Extracts; Solanine; Solanum tuberosum | 2013 |
Glycoalkaloid and calystegine levels in table potato cultivars subjected to wounding, light, and heat treatments.
Topics: Crops, Agricultural; Food Handling; Food Quality; Glycosylation; Hot Temperature; Light; Mechanical Phenomena; Nortropanes; Plant Tubers; Solanaceous Alkaloids; Solanine; Solanum tuberosum; Species Specificity; Stereoisomerism; Sweden; Up-Regulation | 2013 |
Synergistic cytotoxicity induced by α-solanine and α-chaconine.
Topics: Animals; Biological Transport; Cell Line, Tumor; Cell Membrane; Cell Survival; NAD; Rats; Solanine; Solanum tuberosum; Toxins, Biological | 2013 |
Effect of genotype and environment on the glycoalkaloid content of rare, heritage, and commercial potato varieties.
Topics: Agriculture; Diet; Environment; Food Safety; Genotype; Humans; Plant Tubers; Solanine; Solanum tuberosum | 2014 |
Detection of glycoalkaloids using disposable biosensors based on genetically modified enzymes.
Topics: Acetylcholinesterase; Biosensing Techniques; Butyrylcholinesterase; Disposable Equipment; Genetic Engineering; Solanine; Solanum tuberosum | 2014 |
[Determination of alpha-solanine, alpha-chaconine and solanidine in plasma and urine by ultra-performance liquid chromatography-triple quadrupole mass spectrometry].
Topics: Chromatography, High Pressure Liquid; Diosgenin; Humans; Solanine; Solid Phase Extraction; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2014 |
α-Chaconine isolated from a Solanum tuberosum L. cv Jayoung suppresses lipopolysaccharide-induced pro-inflammatory mediators via AP-1 inactivation in RAW 264.7 macrophages and protects mice from endotoxin shock.
Topics: Animals; Cell Line; Cyclooxygenase 2; Endotoxins; Inflammation; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Macrophages; Male; MAP Kinase Kinase 4; MAP Kinase Kinase 7; Mice; Mice, Inbred C57BL; Phosphorylation; Solanine; Solanum tuberosum; Transcription Factor AP-1; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 2015 |
Recovery of steroidal alkaloids from potato peels using pressurized liquid extraction.
Topics: Alkaloids; Diosgenin; Methanol; Phytochemicals; Solanaceous Alkaloids; Solanine; Solanum tuberosum; Solid Phase Extraction | 2015 |
Characterization and Transcriptional Profile of Genes Involved in Glycoalkaloid Biosynthesis in New Varieties of Solanum tuberosum L.
Topics: Alkaloids; Biosynthetic Pathways; Plant Proteins; Plant Tubers; Promoter Regions, Genetic; Solanine; Solanum tuberosum; Transcription, Genetic | 2016 |
Antifungal activity of secondary plant metabolites from potatoes (Solanum tuberosum L.): Glycoalkaloids and phenolic acids show synergistic effects.
Topics: Antifungal Agents; Caffeic Acids; Diosgenin; Fungi; Microbial Sensitivity Tests; Phenols; Solanine; Solanum tuberosum | 2016 |
Impact of light-exposure on the metabolite balance of transgenic potato tubers with modified glycoalkaloid biosynthesis.
Topics: Chlorophyll; Chromatography, Liquid; Gas Chromatography-Mass Spectrometry; Light; Mass Spectrometry; Plant Tubers; Plants, Genetically Modified; Solanaceous Alkaloids; Solanine; Solanum tuberosum | 2016 |
Effect of Drying Methods on the Steroidal Alkaloid Content of Potato Peels, Shoots and Berries.
Topics: Alkaloids; Chromatography, High Pressure Liquid; Freeze Drying; Fruit; Phytosterols; Plant Shoots; Solanine; Solanum tuberosum; Tandem Mass Spectrometry | 2016 |
Solanum tuberosum and Lycopersicon esculentum Leaf Extracts and Single Metabolites Affect Development and Reproduction of Drosophila melanogaster.
Topics: Animals; Body Size; Drosophila melanogaster; Female; Male; Pest Control, Biological; Plant Extracts; Plant Leaves; Reproduction; Solanine; Solanum lycopersicum; Solanum tuberosum; Tomatine | 2016 |
Two Cytochrome P450 Monooxygenases Catalyze Early Hydroxylation Steps in the Potato Steroid Glycoalkaloid Biosynthetic Pathway.
Topics: Biosynthetic Pathways; Breeding; Crops, Agricultural; Cytochrome P-450 Enzyme System; Gene Silencing; Hydroxylation; Phenotype; Phytosterols; Plant Proteins; Plant Tubers; Solanine; Solanum tuberosum | 2016 |
Isolation and chemoenzymatic treatment of glycoalkaloids from green, sprouting and rotting Solanum tuberosum potatoes for solanidine recovery.
Topics: Animals; beta-Glucosidase; Chromatography, High Pressure Liquid; Diosgenin; Hydrogen-Ion Concentration; Periplaneta; Solanine; Solanum tuberosum | 2017 |
The Impact of Steroidal Glycoalkaloids on the Physiology of Phytophthora infestans, the Causative Agent of Potato Late Blight.
Topics: Carbohydrate Sequence; Diosgenin; Fungal Proteins; Glycoside Hydrolases; Glycosylation; Host-Pathogen Interactions; Molecular Structure; Mycelium; Phytophthora infestans; Plant Diseases; Solanaceous Alkaloids; Solanine; Solanum lycopersicum; Solanum tuberosum; Steroids | 2017 |
α-Chaconine and α-Solanine Inhibit RL95-2 Endometrium Cancer Cell Proliferation by Reducing Expression of Akt (Ser473) and ERα (Ser167).
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Down-Regulation; Endometrial Neoplasms; Estrogen Receptor alpha; Female; Humans; Inhibitory Concentration 50; Phosphorylation; Proto-Oncogene Proteins c-akt; Signal Transduction; Solanine; Time Factors | 2018 |
Synthesis and insecticidal activities of novel solanidine derivatives.
Topics: Animals; Aphids; Diosgenin; Fertility; Insecticides; Nymph; Solanine; Solanum tuberosum | 2019 |
RNA Sequencing Reveals That Both Abiotic and Biotic Stress-Responsive Genes are Induced during Expression of Steroidal Glycoalkaloid in Potato Tuber Subjected to Light Exposure.
Topics: Disease Resistance; Exome Sequencing; Gene Expression Regulation, Plant; Light; Plant Tubers; RNA-Seq; Secondary Metabolism; Solanine; Solanum tuberosum; Stress, Physiological; Transcriptome | 2019 |
Discovery of a Bacterial Gene Cluster for Deglycosylation of Toxic Potato Steroidal Glycoalkaloids α-Chaconine and α-Solanine.
Topics: Arthrobacter; Bacterial Proteins; Biotransformation; Glycosylation; Multigene Family; Phylogeny; Solanine; Solanum tuberosum | 2020 |
Glyphosate-based herbicide has soil-mediated effects on potato glycoalkaloids and oxidative status of a potato pest.
Topics: Animals; Antioxidants; Coleoptera; Glutathione Transferase; Glycine; Glyphosate; Herbicides; Larva; Oxidation-Reduction; Oxidative Stress; Soil; Solanine; Solanum tuberosum | 2020 |
The biosynthetic pathway of potato solanidanes diverged from that of spirosolanes due to evolution of a dioxygenase.
Topics: Amino Acid Sequence; Biosynthetic Pathways; Cholesterol; Dioxygenases; Gene Expression Regulation, Plant; Genes, Plant; Hydroxylation; Ketoglutaric Acids; Phylogeny; Plants, Genetically Modified; Secondary Metabolism; Solanine; Solanum lycopersicum; Solanum melongena; Solanum tuberosum; Tomatine | 2021 |
Characterization of C-26 aminotransferase, indispensable for steroidal glycoalkaloid biosynthesis.
Topics: 4-Aminobutyrate Transaminase; Gene Editing; Hydroxylation; Ketocholesterols; Plant Proteins; Plant Tubers; Saponins; Solanine; Solanum tuberosum | 2021 |
Maleic and L-tartaric acids as new anti-sprouting agents for potatoes during storage in comparison to other efficient sprout suppressants.
Topics: Food Storage; Maleates; Plant Tubers; Solanine; Solanum tuberosum; Tartrates | 2021 |
Solanaceae glycoalkaloids: α-solanine and α-chaconine modify the cardioinhibitory activity of verapamil.
Topics: Solanaceae; Solanine; Solanum tuberosum; Verapamil | 2022 |