Page last updated: 2024-08-23

solanine and alpha-chaconine

solanine has been researched along with alpha-chaconine in 109 studies

Research

Studies (109)

TimeframeStudies, this research(%)All Research%
pre-199014 (12.84)18.7374
1990's19 (17.43)18.2507
2000's41 (37.61)29.6817
2010's29 (26.61)24.3611
2020's6 (5.50)2.80

Authors

AuthorsStudies
Alozie, SO; Salunkhe, DK; Sharma, RP1
Nishie, K; Norred, WP; Swain, AP1
Hollingworth, RM; Wierenga, JM1
de Kruijff, B; de Vrije, T; Demel, RA; Fabrie, CH; Jongen, WM; Keukens, EA1
Friedman, M; Henika, PR1
Gabrielsson, J; Hellenäs, KE; Lööf, L; Nyman, A; Slanina, P1
Bergman, K; Cekan, E; Hellenäs, KE; Slanina, P1
Caldwell, KA; Friedman, M; Grosjean, OK; Henika, PR1
Bantle, JA; Friedman, M; Rayburn, JR2
de Kanel, J; Dunlap, L; Hall, TD1
Clarke, GF; Skuce, R; Thorne, HV1
Claringbold, WD; Earthy, ME; Few, JD; McLean, AC; Renwick, JH1
Bourcier, DR; Sharma, RP; Taylor, MJ1
Maga, JA1
Jadhav, SJ; Salunkhe, DK; Sharma, RP1
Bushway, RJ1
Hopkins, J1
Crawford, L; Myhr, B1
Wang, XG1
Chupin, V; de Kruijff, B; de Vrije, T; de Waard, P; Jongen, WM; Keukens, EA; Plasman, HH; Thiel, F; van den Boom, C1
Friedman, M; Henika, PR; Mackey, BE1
Anderson, D; Hughes, JA; Phillips, BJ; Phillips, JC; Tahourdin, CS; Walters, DG1
Bantle, JA; Friedman, M; Qualls, CW; Rayburn, JR1
Fukuhara, K; Kubo, I1
Brown, S; Cornell, JA; Graham, EM; Nigg, HN; Ramos, LE; Sterling, J1
Leonard, AL; Roddick, JG1
Brown, MS; Friedman, M; McDonald, GM1
Serrano, B; Sotelo, A1
Fung, DL; Gronert, GA; Krasowski, MD; McGehee, DS; Moss, J; Wilson, B1
Blankemeyer, JT; Friedman, M; McWilliams, ML1
Friedman, M; Kozukue, N; Tsuchida, H1
Driedger, DR; Sporns, P1
Jones, JL; Roddick, JG; Smith, DB1
Goethals, G; Grand, E; Lequart, V; Martin, P; Morillo, M; Usubillaga, A; Villa, P1
Tibbitts, TW; Wheeler, RM1
Charette, AB; Grenon, M; Lemire, A; Martel, J; Pourashraf, M1
Cardi, T; Carputo, D; Esposito, F; Filippone, E; Fogliano, V1
Doyle, J; Fedorak, RN; Jewel, L; Patel, B; Schutte, R; Sporns, P1
Kepczyński, J; Prescha, A; Szopa, J; Zuk, M1
Bodart, P; Noirfalise, A1
Friedman, M; Kozukue, N; Roitman, JN1
HOESS, HG; SCHIEDT, U1
DEPASQUALE, A1
de BOER, J1
El'skaya, AV; Jaffrezic-Renault, N; Korpan, YI; Martelet, C; Nazarenko, EA; Skryshevskaya, IV1
Baek, EJ; Chang, EY; Chang, JS; Friedman, M; Han, JS; Kozukue, N; Lee, KR; Park, JH1
Armer, CA1
Backleh, M; Coelhan, M; Ekici, P; Leupold, G; Parlar, H1
JOHNSON, CC; JOHNSON, G; POE, CF1
Anttila, K; Hartikainen, H; Ollilainen, V; Seppänen, M; Turakainen, M; Väänänen, T1
Bunch, TD; Evans, RC; Gaffield, W; Panter, KE; Wang, S1
Mensinga, TT; Meulenbelt, J; Rompelberg, CJ; Sips, AJ; van den Top, HJ; van Egmond, HP; van Twillert, K1
Kan, K; Saito, K; Shindo, T; Ushiyama, H; Yasuda, K1
Friedman, M; Kim, HJ; Kozukue, N; Lee, IS; Lee, KR1
Kim, JA; Kozukue, N; Lee, KR; Paek, SH; Yang, SA1
Friedman, M2
Gibson, DM; Krasnoff, SB; Loria, R; Wach, MJ1
Baykus, H; Garza, C; Kuiper, H; Mandimika, T; Peijnenburg, A; Poortman, J2
Hirokado, M; Kamata, K; Kan, K; Saito, K; Shimoi, T; Ushiyama, H1
Fogelman, E; Ginzberg, I; Krits, P1
Baykus, H; Garza, C; Jeurink, P; Kuiper, H; Mandimika, T; Peijnenburg, A; Poortman, J; Vissers, Y1
Chen, PS; Jeng, YF; Shih, YW; Wang, CJ; Wu, CH1
Hansen, HC; Hansen, TH; Jacobsen, OS; Jensen, PH; Juhler, RK; Nielsen, J; Nielsen, NJ; Strobel, BW1
Christiansen, J; Kirk, HG; Labouriau, R; Olsson, K; Sørensen, KK1
Dinkins, CL; Peterson, RK1
Conner, S; Davies, H; Langkilde, S; Meyer, O; Poulsen, M; Schrøder, M; Stewart, D1
Langkilde, S; Mandimika, T; Meyer, O; Peijnenburg, A; Poulsen, M; Schrøder, M; Slob, W1
Hansen, HC; Jacobsen, OS; Jensen, PH; Strobel, BW1
Boon, PE; Bosgra, S; Busk, L; Moussavian, S; Rehurkova, I; Ruprich, J; Svensson, K; Van der Voet, H; Van Klaveren, JD1
Hansen, HC; Henriksen, T; Jacobsen, OS; Jensen, PH; Strobel, BW1
Andolfi, A; Carputo, D; Cimmino, A; Evidente, A; Frusciante, L; Savarese, S1
Kroh, LW; Mäder, J; Rawel, H1
Churchill, T; Driedger, D; Fedorak, RN; Foshaug, R; Iablokov, V; Meddings, J; Sydora, BC1
Chang, YT; Chen, PH; Chen, PS; Huang, ET; Liu, CR; Lu, MK; Shih, YW1
Miller, JC; Reddivari, L; Safe, SH; Vanamala, J1
Cahill, MG; Caprioli, G; James, KJ; Vittori, S1
Demirel, U; Fogelman, E; Ginzberg, I; Mweetwa, AM; Thippeswamy, M; Tokuhisa, J; Veilleux, RE1
Asghar, A; Aziz, A; Butt, MS; Randhawa, MA; Shibamoto, T; Yasin, M1
Belknap, WR; Conner, S; Danier, J; Davies, HV; Engel, KH; Frank, T; Knudsen, I; Langkilde, S; McCue, KF; Meyer, O; Poulsen, M; Rychlik, M; Schrøder, M; Shepherd, LV; Stewart, D1
Deusser, H; Evers, D; Guignard, C; Hoffmann, L1
Attoumbré, J; Baltora-Rosset, S; Giordanengo, P; Lesur, D1
Brunton, NP; Collins, SG; Hossain, MB; Jones, PW; Kenny, OM; Maguire, AR; McCarthy, CM; O'Brien, NM; Rai, DK1
Andersson, HC; Arif, U; Hajšlová, J; Jonsson, L; Krtková, V; Meijer, J; Petersson, EV; Schulzova, V; Sitbon, F1
Matsuda, T; Yamashoji, S1
Gaffney, M; O'Brien, N; Reilly, K; Valcarcel, J1
Chira, A; Espinoza, MA; Istamboulie, G; Marty, JL; Noguer, T; Stoytcheva, M1
Cai, X; Zhang, X1
An, HJ; Jang, DS; Kim, NJ; Lee, HH; Lee, HJ; Lee, KG; Lee, KT; Lee, SG; Nam, JH; Shin, JS1
Aguiló-Aguayo, I; Brunton, NP; Hossain, MB; Rai, DK; Rawson, A1
de Oliveira, LA; Frazzon, J; Hutten, RC; Kok, EJ; Mariot, RF; Staats, M; van Dijk, JP; Voorhuijzen, MM1
Gänzle, MG; Sánchez-Maldonado, AF; Schieber, A1
Alexander, CJ; Belknap, WR; Davies, HV; Hackett, CA; McCue, KF; McNicol, JW; McRae, D; Shepherd, LV; Sungurtas, JA1
Brunton, NP; Hossain, MB; Rai, DK1
Adamski, Z; Bufo, SA; Büyükgüzel, E; Büyükgüzel, K; Chudzińska, E; Erdem, M; Falabella, P; Marciniak, P; Miądowicz-Kobielska, M; Scrano, L; Ventrella, E1
Mizutani, M; Muranaka, T; Nakayasu, M; Ohyama, K; Saito, K; Seki, H; Umemoto, N; Yotsu-Yamashita, M1
Combes, D; Due, AE; Koffi, GY; Remaud-Simeon, M1
Bulone, V; Dahlin, P; Ekengren, S; McKee, LS; Müller, MC1
Karaboğa Arslan, AK; Yerer, MB1
Ameline, A; Attoumbré, J; Beaulieu, R; Chesnais, Q; Giordanengo, P; Gobert, V; Grand, E; Kovensky, J; Stasik, I1
Chen, Z; Kang, Y; Qin, S; Zhang, W; Zuo, C1
Greve-Poulsen, M; Hennessy, RC; Larsen, LB; Nielsen, SD; Stougaard, P; Sørensen, OB1
Helander, M; Lindström, L; Margus, A; Rainio, MJ; Saikkonen, K; Salminen, JP; Virtanen, V1
Akiyama, R; Kato, J; Lee, HJ; Mizutani, M; Muranaka, T; Nakayasu, M; Saito, K; Sugimoto, Y; Umemoto, N; Watanabe, B1
Akiyama, R; Lee, HJ; Miyachi, H; Mizutani, M; Muranaka, T; Nakayasu, M; Ohyama, K; Saito, K; Sugimoto, Y; Umemoto, N; Watanabe, B1
Bhattacharya, E; Mandal Biswas, S; Pramanik, P1
Adamski, Z; Bufo, SA; Chowański, S; Mańczak, D; Marciniak, P; Scrano, L; Spochacz, M; Szymczak-Cendlak, M; Walkowiak-Nowicka, K; Winkiel, M1

Reviews

7 review(s) available for solanine and alpha-chaconine

ArticleYear
Potato glycoalkaloids.
    Critical reviews in food science and nutrition, 1980, Volume: 12, Issue:4

    Topics: Diosgenin; Food Preservation; Models, Biological; Plants, Edible; Solanaceous Alkaloids; Solanine; Species Specificity; Vegetables

1980
Naturally occurring toxic alkaloids in foods.
    Critical reviews in toxicology, 1981, Volume: 9, Issue:1

    Topics: Alkaloids; Animals; Chemical Phenomena; Chemistry; Humans; Light; Solanaceous Alkaloids; Solanine; Tomatine; Vegetables

1981
The glycoalkaloids: naturally of interest (but a hot potato?).
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1995, Volume: 33, Issue:4

    Topics: Animals; Congenital Abnormalities; Female; Foodborne Diseases; Humans; Male; Mutagenicity Tests; Mutation; Pregnancy; Reproduction; Solanine; Solanum tuberosum; United Kingdom

1995
Steroidal glycoalkaloids in Andean potatoes.
    Advances in experimental medicine and biology, 1996, Volume: 405

    Topics: Bolivia; Chromatography; Chromatography, High Pressure Liquid; Glycosides; Solanine; Solanum tuberosum; Steroids

1996
Potato glycoalkaloids: true safety or false sense of security?
    Trends in biotechnology, 2004, Volume: 22, Issue:3

    Topics: Abnormalities, Drug-Induced; Animals; Cell Division; Cell Line, Tumor; Cell Physiological Phenomena; DNA Damage; Humans; Plant Poisoning; Solanaceous Alkaloids; Solanine; Solanum tuberosum; Viruses

2004
Potato glycoalkaloids and metabolites: roles in the plant and in the diet.
    Journal of agricultural and food chemistry, 2006, Nov-15, Volume: 54, Issue:23

    Topics: Animals; Carbohydrate Sequence; Diet; Glycosides; Humans; Molecular Sequence Data; Plant Physiological Phenomena; Solanaceous Alkaloids; Solanine; Solanum tuberosum

2006
Chemistry and anticarcinogenic mechanisms of glycoalkaloids produced by eggplants, potatoes, and tomatoes.
    Journal of agricultural and food chemistry, 2015, Apr-08, Volume: 63, Issue:13

    Topics: Animals; Anticarcinogenic Agents; Apoptosis; Cell Line, Tumor; Humans; Mice; Solanaceous Alkaloids; Solanine; Solanum lycopersicum; Solanum melongena; Solanum tuberosum; Structure-Activity Relationship; Tomatine

2015

Trials

1 trial(s) available for solanine and alpha-chaconine

ArticleYear
Potato glycoalkaloids and adverse effects in humans: an ascending dose study.
    Regulatory toxicology and pharmacology : RTP, 2005, Volume: 41, Issue:1

    Topics: Adult; Area Under Curve; Biological Availability; Dose-Response Relationship, Drug; Female; Half-Life; Humans; Male; Middle Aged; Solanine; Solanum tuberosum

2005

Other Studies

101 other study(ies) available for solanine and alpha-chaconine

ArticleYear
Excretion of alpha-chaconine-3H, a steroidal glycoalkaloid from Solanum tuberosum L. and its metabolites in hamsters.
    Pharmacological research communications, 1979, Volume: 11, Issue:6

    Topics: Animals; Cricetinae; Feces; Mesocricetus; Solanine; Time Factors

1979
Pharmacology and toxicology of chaconine and tomatine.
    Research communications in chemical pathology and pharmacology, 1975, Volume: 12, Issue:4

    Topics: Abnormalities, Drug-Induced; Alkaloids; Animals; Anura; Birth Weight; Blood Pressure; Chick Embryo; Chickens; Electroencephalography; Glycosides; Guinea Pigs; Heart Rate; Ileum; In Vitro Techniques; Lethal Dose 50; Male; Mice; Muscle Contraction; Muscle, Smooth; Rabbits; Solanine; Species Specificity; Teratogens; Time Factors; Tomatine

1975
Inhibition of insect acetylcholinesterase by the potato glycoalkaloid alpha-chaconine.
    Natural toxins, 1992, Volume: 1, Issue:2

    Topics: Adaptation, Physiological; Animals; Cholinesterase Inhibitors; Insecta; Insecticide Resistance; Solanine; Solanum tuberosum; Species Specificity

1992
Dual specificity of sterol-mediated glycoalkaloid induced membrane disruption.
    Biochimica et biophysica acta, 1992, Oct-05, Volume: 1110, Issue:2

    Topics: Calorimetry, Differential Scanning; Carbohydrate Sequence; Cell Membrane; Diosgenin; Freeze Fracturing; Lipid Bilayers; Microscopy, Electron; Molecular Sequence Data; Solanaceous Alkaloids; Solanine; Sterols; Substrate Specificity; Tomatine

1992
Absence of genotoxicity of potato alkaloids alpha-chaconine, alpha-solanine and solanidine in the Ames Salmonella and adult and foetal erythrocyte micronucleus assays.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1992, Volume: 30, Issue:8

    Topics: Animals; Diosgenin; Female; Fetus; Injections, Intraperitoneal; Male; Mice; Micronucleus Tests; Mortality; Mutagenicity Tests; Mutagens; Salmonella typhimurium; Solanaceous Alkaloids; Solanine; Solanum tuberosum

1992
Determination of potato glycoalkaloids and their aglycone in blood serum by high-performance liquid chromatography. Application to pharmacokinetic studies in humans.
    Journal of chromatography, 1992, Jan-03, Volume: 573, Issue:1

    Topics: Adult; Alkaloids; Chromatography, High Pressure Liquid; Diosgenin; Half-Life; Humans; Male; Solanaceous Alkaloids; Solanine; Solanum tuberosum; Spectrophotometry, Ultraviolet

1992
Studies of embryotoxicity and the incidence of external malformations after continuous intravenous infusion of alpha-chaconine in pregnant rats.
    Pharmacology & toxicology, 1992, Volume: 70, Issue:5 Pt 1

    Topics: Animals; Female; Incidence; Infusions, Intravenous; Pregnancy; Rats; Rats, Inbred Strains; Solanine; Teratogens

1992
Hepatic ornithine decarboxylase induction by potato glycoalkaloids in rats.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1991, Volume: 29, Issue:8

    Topics: Animals; Diosgenin; Enzyme Induction; Injections, Intraperitoneal; Liver; Male; Ornithine Decarboxylase; Rats; Rats, Inbred Strains; Solanaceous Alkaloids; Solanine; Solanum tuberosum

1991
Developmental toxicology of potato alkaloids in the frog embryo teratogenesis assay--Xenopus (FETAX).
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1991, Volume: 29, Issue:8

    Topics: Abnormalities, Drug-Induced; Animals; Diosgenin; Embryo, Nonmammalian; Lethal Dose 50; Microsomes, Liver; Rats; Solanaceous Alkaloids; Solanine; Solanum tuberosum; Teratogens; Xenopus

1991
Extending the detection limit of the TDx fluorescence polarization immunoassay for benzoylecgonine in urine.
    Clinical chemistry, 1989, Volume: 35, Issue:10

    Topics: Autoanalysis; Cocaine; False Negative Reactions; Fluorescence Polarization; Humans; Immunoassay; Mathematics; Solanine; Statistics as Topic; Substance-Related Disorders

1989
The inactivation of herpes simplex virus by some Solanaceae glycoalkaloids.
    Antiviral research, 1985, Volume: 5, Issue:6

    Topics: Animals; Cell Line; Cell Membrane; Cell Survival; Chlorocebus aethiops; Diosgenin; Erythrocyte Membrane; Monosaccharides; Sheep; Simplexvirus; Solanaceous Alkaloids; Solanine; Structure-Activity Relationship; Tomatine

1985
Neural-tube defects produced in Syrian hamsters by potato glycoalkaloids.
    Teratology, 1984, Volume: 30, Issue:3

    Topics: Abnormalities, Drug-Induced; Animals; Cricetinae; Dose-Response Relationship, Drug; Female; Humans; Male; Mesocricetus; Neural Tube Defects; Pregnancy; Sex Factors; Solanine; Vegetables

1984
Subcellular distribution of alpha-chaconine in mouse hepatocytes.
    Drug and chemical toxicology, 1983, Volume: 6, Issue:2

    Topics: Animals; Enzyme Induction; Female; Liver; Mice; Solanine

1983
High-performance liquid chromatographic separation of potato glycoalkaloids using a radially compressed amino column.
    Journal of chromatography, 1982, Sep-24, Volume: 247, Issue:1

    Topics: Alkaloids; Chromatography, High Pressure Liquid; Solanine; Solvents; Vegetables

1982
A preliminary assessment of the toxic and mutagenic potential of steroidal alkaloids in transgenic mice.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1995, Volume: 33, Issue:3

    Topics: Alkaloids; Animals; Diosgenin; Embryonic and Fetal Development; Female; Gene Expression Regulation, Developmental; Lac Operon; Liver; Mice; Mice, Inbred BALB C; Mice, Transgenic; Mutation; Pregnancy; Solanaceous Alkaloids; Solanine; Solanum tuberosum; Teratogens; Tretinoin; Veratrum Alkaloids

1995
[Teratogenic effect of potato glycoalkaloids].
    Zhonghua fu chan ke za zhi, 1993, Volume: 28, Issue:2

    Topics: Abnormalities, Drug-Induced; Animals; Female; Fetal Death; Fetal Growth Retardation; Lethal Dose 50; Mice; Neural Tube Defects; Pregnancy; Solanine; Solanum tuberosum

1993
Molecular basis of glycoalkaloid induced membrane disruption.
    Biochimica et biophysica acta, 1995, Dec-13, Volume: 1240, Issue:2

    Topics: Carbohydrate Sequence; Magnetic Resonance Spectroscopy; Membranes, Artificial; Microscopy, Electron; Models, Molecular; Molecular Sequence Data; Solanine; Sterols; Tomatine

1995
Feeding of potato, tomato and eggplant alkaloids affects food consumption and body and liver weights in mice.
    The Journal of nutrition, 1996, Volume: 126, Issue:4

    Topics: Alkaloids; Animals; Body Weight; Dehydroepiandrosterone; Diosgenin; Eating; Female; Liver; Mice; Organ Size; Plants, Edible; Solanaceous Alkaloids; Solanine; Solanum lycopersicum; Solanum tuberosum; Structure-Activity Relationship; Tomatine; Vegetables

1996
A study of the toxic hazard that might be associated with the consumption of green potato tops.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1996, Volume: 34, Issue:5

    Topics: Animals; Blood Cells; Cell Survival; CHO Cells; Chromatography, High Pressure Liquid; Cricetinae; Humans; Male; Mice; Plant Leaves; Rats; Rats, Sprague-Dawley; Solanine; Solanum tuberosum

1996
Synergistic interaction of glycoalkaloids alpha-chaconine and alpha-solanine on developmental toxicity in Xenopus embryos.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1995, Volume: 33, Issue:12

    Topics: Abnormalities, Drug-Induced; Animals; Drug Synergism; Embryo, Nonmammalian; Embryonic Development; Solanine; Survival Rate; Teratogens; Toxicity Tests; Xenopus

1995
Protective effects of glucose-6-phosphate and NADP against alpha-chaconine-induced developmental toxicity in Xenopus embryos.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1995, Volume: 33, Issue:12

    Topics: Animals; Biotransformation; Embryo, Nonmammalian; Embryonic Development; Glucose-6-Phosphate; Glucosephosphates; Male; Microsomes, Liver; NADP; Rats; Rats, Sprague-Dawley; Solanine; Teratogens; Toxicity Tests; Xenopus

1995
Inhibition of human plasma and serum butyrylcholinesterase (EC 3.1.1.8) by alpha-chaconine and alpha-solanine.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1996, Volume: 33, Issue:2

    Topics: Butyrylcholinesterase; Cholinesterase Inhibitors; Electrophoresis, Polyacrylamide Gel; Humans; Paraoxon; Solanine; Substrate Specificity

1996
Amelioration by glucose-6-phosphate and NADP of potato glycoalkaloid inhibition in cell, enzyme and liposome assays.
    Phytochemistry, 1999, Volume: 51, Issue:1

    Topics: Acetylcholinesterase; Cholinesterase Inhibitors; Glucose-6-Phosphate; Hemolysis; Humans; Liposomes; NADP; Solanine; Solanum tuberosum

1999
Sampling leaves of young potato (Solanum tuberosum) plants for glycoalkaloid analysis.
    Journal of agricultural and food chemistry, 1999, Volume: 47, Issue:6

    Topics: Freeze Drying; Plant Leaves; Solanaceous Alkaloids; Solanine; Solanum tuberosum

1999
High-performance liquid chromatographic determination of the glycoalkaloids alpha-solanine and alpha-chaconine in 12 commercial varieties of Mexican potato.
    Journal of agricultural and food chemistry, 2000, Volume: 48, Issue:6

    Topics: Chromatography, High Pressure Liquid; Humans; Mexico; Safety; Solanine; Solanum tuberosum; Species Specificity

2000
Cholinesterase inhibition by potato glycoalkaloids slows mivacurium metabolism.
    Anesthesiology, 2000, Volume: 93, Issue:2

    Topics: Animals; Cholinesterase Inhibitors; Drug Interactions; Female; Humans; Isoquinolines; Male; Mivacurium; Neuromuscular Nondepolarizing Agents; Rabbits; Solanine; Solanum tuberosum

2000
The folic acid analogue methotrexate protects frog embryo cell membranes against damage by the potato glycoalkaloid alpha-chaconine.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2000, Volume: 38, Issue:10

    Topics: Animals; Carbohydrate Sequence; Cell Membrane; Embryo, Nonmammalian; Folic Acid Antagonists; Methotrexate; Molecular Sequence Data; Neopterin; Solanine; Solanum tuberosum; Spectrometry, Fluorescence; Xenopus laevis

2000
Tracer studies on the incorporation of [2-14C]-DL-mevalonate into chlorophylls a and b, alpha-chaconine, and alpha-solanine of potato sprouts.
    Journal of agricultural and food chemistry, 2001, Volume: 49, Issue:1

    Topics: Carbon Radioisotopes; Chlorophyll; Chlorophyll A; Chromatography, High Pressure Liquid; Mevalonic Acid; Solanine; Solanum tuberosum

2001
Immunoaffinity sample purification and MALDI-TOF MS analysis of alpha-Solanine and alpha-chaconine in serum.
    Journal of agricultural and food chemistry, 2001, Volume: 49, Issue:2

    Topics: Animals; Antibodies; Chromatography, Affinity; Female; Rabbits; Sensitivity and Specificity; Solanine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2001
Synergism between the potato glycoalkaloids alpha-chaconine and alpha-solanine in inhibition of snail feeding.
    Phytochemistry, 2001, Volume: 57, Issue:2

    Topics: Animals; Drug Synergism; Feeding Behavior; Helix, Snails; Solanine; Solanum tuberosum

2001
Synthesis of peracetylated chacotriose.
    Carbohydrate research, 2001, Sep-07, Volume: 334, Issue:4

    Topics: Carbohydrate Conformation; Carbohydrate Sequence; Molecular Sequence Data; Peracetic Acid; Plant Extracts; Solanaceous Alkaloids; Solanine; Solanum tuberosum; Tropanes

2001
Utilization of potatoes in bioregenerative life support systems.
    Advances in space research : the official journal of the Committee on Space Research (COSPAR), 1987, Volume: 7, Issue:4

    Topics: Carbon Dioxide; Ecological Systems, Closed; Life Support Systems; Light; Lighting; Organ Size; Photons; Photoperiod; Plant Stems; Solanine; Solanum tuberosum; Temperature; Toxins, Biological

1987
Practical and highly regio- and stereoselective synthesis of 2-substituted dihydropyridines and piperidines: application to the synthesis of (-)-coniine.
    Journal of the American Chemical Society, 2001, Nov-28, Volume: 123, Issue:47

    Topics: Dihydropyridines; Oxidation-Reduction; Piperidines; Solanine; Stereoisomerism; Substrate Specificity

2001
Glycoalkaloid content and chemical composition of potatoes improved with nonconventional breeding approaches.
    Journal of agricultural and food chemistry, 2002, Mar-13, Volume: 50, Issue:6

    Topics: Chitinases; Food Technology; Genetic Engineering; Genotype; Plant Proteins; Plants, Genetically Modified; Solanine; Solanum tuberosum; Transfection

2002
Potato glycoalkaloids adversely affect intestinal permeability and aggravate inflammatory bowel disease.
    Inflammatory bowel diseases, 2002, Volume: 8, Issue:5

    Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; In Vitro Techniques; Inflammatory Bowel Diseases; Intestinal Mucosa; Mice; Permeability; Solanaceous Alkaloids; Solanine; Solanum tuberosum; Time Factors

2002
ADP ribosylation factor regulates metabolism and antioxidant capacity of transgenic potato tubers.
    Journal of agricultural and food chemistry, 2003, Jan-01, Volume: 51, Issue:1

    Topics: 14-3-3 Proteins; ADP-Ribosylation Factors; Amino Acids; Antioxidants; Carbohydrates; DNA, Antisense; Fatty Acids; Flavonoids; Gene Expression; Lipids; Phenotype; Plant Proteins; Plant Roots; Plants, Genetically Modified; Solanine; Solanum; Transformation, Genetic; Tyrosine 3-Monooxygenase

2003
[Glycoalkaloids in potatoes].
    Revue medicale de Liege, 2003, Volume: 58, Issue:1

    Topics: Alkaloids; Molecular Structure; Solanine; Solanum tuberosum

2003
Glycoalkaloid and calystegine contents of eight potato cultivars.
    Journal of agricultural and food chemistry, 2003, May-07, Volume: 51, Issue:10

    Topics: Chromatography, High Pressure Liquid; Freeze Drying; Gas Chromatography-Mass Spectrometry; Hydrogen-Ion Concentration; Nortropanes; Plant Extracts; Solanaceous Alkaloids; Solanine; Solanum tuberosum; Vegetables

2003
[On the biogenesis of alkaloids. III. Lysine as the precursor to coniine].
    Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 1962, Dec-15, Volume: 330

    Topics: Alkaloids; Humans; Lysine; Piperidines; Solanine

1962
[SPECTROPHOROMETRIC DETERMINATION OF CONIINE].
    Archivio italiano di scienze farmacologiche, 1963, Volume: 13

    Topics: Alkaloids; Hypertension; Hypertension, Renal; Piperidines; Research; Solanine; Spectrophotometry

1963
The death of Socrates. A historical and experimental study on the actions of coniine and conium maculatum.
    Archives internationales de pharmacodynamie et de therapie, 1950, Sep-01, Volume: 83, Issue:4

    Topics: Alkaloids; Conium; Piperidines; Solanine

1950
Glycoalkaloids and metabolites inhibit the growth of human colon (HT29) and liver (HepG2) cancer cells.
    Journal of agricultural and food chemistry, 2004, May-19, Volume: 52, Issue:10

    Topics: Alkaloids; Cell Division; Colonic Neoplasms; Humans; Hydrolysis; Liver Neoplasms; Solanine; Solanum; Solanum lycopersicum; Structure-Activity Relationship; Tomatine; Tumor Cells, Cultured

2004
Colorado potato beetle toxins revisited: evidence the beetle does not sequester host plant glycoalkaloids.
    Journal of chemical ecology, 2004, Volume: 30, Issue:4

    Topics: Animals; Coleoptera; Feeding Behavior; Hemolymph; Oregon; Plant Leaves; Solanine; Solanum tuberosum

2004
Enrichment of the glycoalkaloids alpha-solanine and alpha-chaconine from potato juice by adsorptive bubble separation using a pH gradient.
    Journal of separation science, 2004, Volume: 27, Issue:12

    Topics: Alkaloids; Chromatography, High Pressure Liquid; Hydrogen-Ion Concentration; Plant Extracts; Solanine; Solanum tuberosum; Time Factors

2004
Toxicity of alkaloids for certain bacteria; coniine, nicotine, and strychnine.
    Acta pharmacologica et toxicologica, 1949, Volume: 5, Issue:3

    Topics: Alkaloids; Bacteria; Humans; Nicotine; Piperidines; Solanine; Strychnine

1949
Effect of selenate supplementation on glycoalkaloid content of potato (Solanum tuberosum L.).
    Journal of agricultural and food chemistry, 2004, Nov-17, Volume: 52, Issue:23

    Topics: Alkaloids; Chromatography, High Pressure Liquid; Plant Tubers; Selenic Acid; Selenium Compounds; Solanine; Solanum tuberosum

2004
Effects of steroidal glycoalkaloids from potatoes (Solanum tuberosum) on in vitro bovine embryo development.
    Animal reproduction science, 2005, Volume: 85, Issue:3-4

    Topics: Animals; Cattle; Diosgenin; Embryonic Development; Fertilization in Vitro; Solanaceous Alkaloids; Solanine; Solanum tuberosum; Tissue Culture Techniques

2005
[Contents and its change during storage of alpha-solanine and alpha-chaconine in potatoes].
    Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan, 2004, Volume: 45, Issue:5

    Topics: Chromatography, High Pressure Liquid; Food Preservation; Solanine; Solanum tuberosum

2004
Anticarcinogenic effects of glycoalkaloids from potatoes against human cervical, liver, lymphoma, and stomach cancer cells.
    Journal of agricultural and food chemistry, 2005, Jul-27, Volume: 53, Issue:15

    Topics: Anticarcinogenic Agents; Antineoplastic Agents; Cell Death; Cell Line, Tumor; Diet; Drug Synergism; Female; Humans; Liver Neoplasms; Lymphoma; Neoplasms; Plant Tubers; Solanine; Solanum tuberosum; Stomach Neoplasms; Uterine Cervical Neoplasms

2005
Alpha-chaconine, a potato glycoalkaloid, induces apoptosis of HT-29 human colon cancer cells through caspase-3 activation and inhibition of ERK 1/2 phosphorylation.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2006, Volume: 44, Issue:6

    Topics: Apoptosis; Caspase 3; Caspases; Enzyme Activation; Enzyme Inhibitors; HT29 Cells; Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Solanine

2006
Effect of carbohydrates on the production of thaxtomin A by Streptomyces acidiscabies.
    Archives of microbiology, 2007, Volume: 188, Issue:1

    Topics: Avena; Carbohydrates; Glucans; Indoles; Piperazines; Plant Extracts; Solanine; Streptomyces; Triticum; Xylans

2007
Induction of the cholesterol biosynthesis pathway in differentiated Caco-2 cells by the potato glycoalkaloid alpha-chaconine.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2007, Volume: 45, Issue:10

    Topics: Biomarkers; Caco-2 Cells; Cell Differentiation; Cholesterol; Cluster Analysis; Data Interpretation, Statistical; Dose-Response Relationship, Drug; Gene Expression; Gene Expression Profiling; Humans; L-Lactate Dehydrogenase; Oligonucleotide Array Sequence Analysis; Solanine; Solanum tuberosum; Up-Regulation

2007
[Survey of glycoalkaloids content in the various potatoes].
    Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan, 2007, Volume: 48, Issue:3

    Topics: Solanaceous Alkaloids; Solanine; Solanum tuberosum

2007
Potato steroidal glycoalkaloid levels and the expression of key isoprenoid metabolic genes.
    Planta, 2007, Volume: 227, Issue:1

    Topics: Gene Expression Regulation, Plant; Genes, Plant; Genotype; Models, Biological; Plant Leaves; Reverse Transcriptase Polymerase Chain Reaction; Solanaceous Alkaloids; Solanine; Solanum tuberosum; Terpenes

2007
Differential gene expression in intestinal epithelial cells induced by single and mixtures of potato glycoalkaloids.
    Journal of agricultural and food chemistry, 2007, Nov-28, Volume: 55, Issue:24

    Topics: Apoptosis; Caco-2 Cells; Cell Cycle; Cholesterol; Dose-Response Relationship, Drug; Gene Expression; Gene Expression Profiling; Humans; Intestinal Mucosa; L-Lactate Dehydrogenase; Lipid Metabolism; Oligonucleotide Array Sequence Analysis; Proteins; Severity of Illness Index; Solanine; Solanum tuberosum

2007
Alpha-chaconine-reduced metastasis involves a PI3K/Akt signaling pathway with downregulation of NF-kappaB in human lung adenocarcinoma A549 cells.
    Journal of agricultural and food chemistry, 2007, Dec-26, Volume: 55, Issue:26

    Topics: Antineoplastic Agents, Phytogenic; Cell Death; Cell Line, Tumor; DNA; Humans; Lung Neoplasms; Neoplasm Invasiveness; Neoplasm Metastasis; NF-kappa B; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Signal Transduction; Solanine

2007
Potato glycoalkaloids in soil-optimising liquid chromatography-time-of-flight mass spectrometry for quantitative studies.
    Journal of chromatography. A, 2008, Feb-22, Volume: 1182, Issue:1

    Topics: Chromatography, Liquid; Molecular Structure; Reproducibility of Results; Soil; Solanaceous Alkaloids; Solanine; Solanum tuberosum; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2008
A major QTL and an SSR marker associated with glycoalkaloid content in potato tubers from Solanum tuberosum x S. sparsipilum located on chromosome I.
    TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik, 2008, Volume: 117, Issue:1

    Topics: Amplified Fragment Length Polymorphism Analysis; Breeding; Chromatography, High Pressure Liquid; Chromosome Mapping; Chromosomes, Plant; Diploidy; DNA, Plant; Genetic Linkage; Genetic Markers; Light; Phenotype; Plant Tubers; Polymerase Chain Reaction; Principal Component Analysis; Quantitative Trait Loci; Repetitive Sequences, Nucleic Acid; Solanine; Solanum tuberosum

2008
A human dietary risk assessment associated with glycoalkaloid responses of potato to Colorado potato beetle defoliation.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2008, Volume: 46, Issue:8

    Topics: Adolescent; Adult; Animals; Child; Child, Preschool; Coleoptera; Diet; Dose-Response Relationship, Drug; Eating; Female; Humans; Infant; Lethal Dose 50; Male; No-Observed-Adverse-Effect Level; Pregnancy; Risk Assessment; Solanine; Solanum tuberosum

2008
Acute toxicity of high doses of the glycoalkaloids, alpha-solanine and alpha-chaconine, in the Syrian Golden hamster.
    Journal of agricultural and food chemistry, 2008, Sep-24, Volume: 56, Issue:18

    Topics: Acetylcholinesterase; Animals; Butyrylcholinesterase; Cricetinae; Dose-Response Relationship, Drug; Female; Intestine, Small; Mesocricetus; Solanine

2008
PI3K/AKT, JNK, and ERK pathways are not crucial for the induction of cholesterol biosynthesis gene transcription in intestinal epithelial cells following treatment with the potato glycoalkaloid alpha-chaconine.
    Journal of agricultural and food chemistry, 2008, Sep-24, Volume: 56, Issue:18

    Topics: Caco-2 Cells; Cholesterol; Epithelial Cells; Extracellular Signal-Regulated MAP Kinases; Gene Expression; Humans; Intestinal Mucosa; JNK Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Solanine; Solanum tuberosum; Sterol Regulatory Element Binding Protein 2

2008
A 28-day repeat dose toxicity study of steroidal glycoalkaloids, alpha-solanine and alpha-chaconine in the Syrian Golden hamster.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2009, Volume: 47, Issue:6

    Topics: Acetylcholinesterase; Animals; Biological Availability; Blood Cell Count; Blood Chemical Analysis; Body Weight; Butyrylcholinesterase; Cholinesterases; Cricetinae; Drinking; Eating; Female; Intubation, Gastrointestinal; Mesocricetus; Oligonucleotide Array Sequence Analysis; RNA; Solanine; Solanum tuberosum

2009
Fate of toxic potato glycoalkaloids in a potato field.
    Journal of agricultural and food chemistry, 2009, Apr-08, Volume: 57, Issue:7

    Topics: Plant Leaves; Plant Stems; Plant Tubers; Seasons; Soil; Solanine; Solanum tuberosum; Water

2009
Probabilistic modelling of exposure doses and implications for health risk characterization: glycoalkaloids from potatoes.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2009, Volume: 47, Issue:12

    Topics: Eating; Environmental Exposure; Europe; Humans; Models, Statistical; Solanine; Solanum tuberosum

2009
Degradation of the potato glycoalkaloids--alpha-solanine and alpha-chaconine in groundwater.
    Bulletin of environmental contamination and toxicology, 2009, Volume: 82, Issue:6

    Topics: Bacteria; Biotransformation; Fungi; Solanine; Solanum tuberosum; Water Pollutants; Water Supply

2009
Glycoalkaloids as biomarkers for recognition of cultivated, wild, and somatic hybrids of potato.
    Chemistry & biodiversity, 2009, Volume: 6, Issue:4

    Topics: Alkaloids; Biomarkers; Chromatography, High Pressure Liquid; Hybridization, Genetic; Plant Tubers; Solanine; Solanum tuberosum

2009
Composition of phenolic compounds and glycoalkaloids alpha-solanine and alpha-chaconine during commercial potato processing.
    Journal of agricultural and food chemistry, 2009, Jul-22, Volume: 57, Issue:14

    Topics: Chlorogenic Acid; Chromatography, High Pressure Liquid; Food Handling; Food Preservation; Hot Temperature; Phenols; Solanine; Solanum tuberosum

2009
Naturally occurring glycoalkaloids in potatoes aggravate intestinal inflammation in two mouse models of inflammatory bowel disease.
    Digestive diseases and sciences, 2010, Volume: 55, Issue:11

    Topics: Animals; Colitis, Ulcerative; Cooking; Crohn Disease; Cytokines; Dextran Sulfate; Disease Models, Animal; Genetic Predisposition to Disease; Inflammatory Bowel Diseases; Intestinal Mucosa; Mice; Peroxidase; Solanaceous Alkaloids; Solanine; Solanum tuberosum

2010
alpha-Chaconine inhibits angiogenesis in vitro by reducing matrix metalloproteinase-2.
    Biological & pharmaceutical bulletin, 2010, Volume: 33, Issue:4

    Topics: Angiogenesis Inhibitors; Animals; Cattle; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Endothelial Cells; Extracellular Signal-Regulated MAP Kinases; JNK Mitogen-Activated Protein Kinases; Matrix Metalloproteinase 2; Neovascularization, Pathologic; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphorylation; Plant Extracts; Proto-Oncogene Proteins c-akt; Seedlings; Solanine; Solanum tuberosum

2010
The bioactive compounds alpha-chaconine and gallic acid in potato extracts decrease survival and induce apoptosis in LNCaP and PC3 prostate cancer cells.
    Nutrition and cancer, 2010, Volume: 62, Issue:5

    Topics: Antigens, CD1; Apoptosis; Caspases; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p27; Extracellular Signal-Regulated MAP Kinases; Gallic Acid; Humans; Intracellular Signaling Peptides and Proteins; JNK Mitogen-Activated Protein Kinases; Male; Plant Extracts; Prostatic Neoplasms; Solanine; Solanum tuberosum

2010
Elucidation of the mass fragmentation pathways of potato glycoalkaloids and aglycons using Orbitrap mass spectrometry.
    Journal of mass spectrometry : JMS, 2010, Volume: 45, Issue:9

    Topics: Solanaceous Alkaloids; Solanine; Solanum tuberosum; Tandem Mass Spectrometry; Toxins, Biological

2010
Induction of potato steroidal glycoalkaloid biosynthetic pathway by overexpression of cDNA encoding primary metabolism HMG-CoA reductase and squalene synthase.
    Planta, 2012, Volume: 235, Issue:6

    Topics: Alkaloids; Biosynthetic Pathways; Chromatography, High Pressure Liquid; DNA, Complementary; Farnesyl-Diphosphate Farnesyltransferase; Gene Expression Regulation, Plant; Genes, Plant; Hydroxymethylglutaryl CoA Reductases; Phytosterols; Plant Leaves; Plants, Genetically Modified; RNA, Messenger; Sequence Homology, Nucleic Acid; Solanine; Solanum tuberosum

2012
Glycoalkaloids (α-chaconine and α-solanine) contents of selected Pakistani potato cultivars and their dietary intake assessment.
    Journal of food science, 2012, Volume: 77, Issue:3

    Topics: Chromatography, High Pressure Liquid; Food Handling; Food Safety; Humans; Pakistan; Reproducibility of Results; Solanine; Solanum tuberosum

2012
Compositional and toxicological analysis of a GM potato line with reduced α-solanine content--a 90-day feeding study in the Syrian Golden hamster.
    Regulatory toxicology and pharmacology : RTP, 2012, Volume: 64, Issue:1

    Topics: Animal Feed; Animals; Blood Chemical Analysis; Consumer Product Safety; Cricetinae; Dose-Response Relationship, Drug; Female; Food, Genetically Modified; Freeze Drying; Hematologic Tests; Mesocricetus; Nutritive Value; Plants, Genetically Modified; Solanine; Solanum tuberosum; Toxicity Tests

2012
Polyphenol and glycoalkaloid contents in potato cultivars grown in Luxembourg.
    Food chemistry, 2012, Dec-15, Volume: 135, Issue:4

    Topics: Chromatography, High Pressure Liquid; Luxembourg; Plant Extracts; Polyphenols; Solanine; Solanum tuberosum; Tandem Mass Spectrometry

2012
Preparative separation of glycoalkaloids α-solanine and α-chaconine by centrifugal partition chromatography.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2012, Nov-01, Volume: 908

    Topics: Centrifugation; Chromatography, High Pressure Liquid; Organic Chemicals; Plant Extracts; Solanine; Solanum tuberosum; Water

2012
Anti-inflammatory properties of potato glycoalkaloids in stimulated Jurkat and Raw 264.7 mouse macrophages.
    Life sciences, 2013, Apr-19, Volume: 92, Issue:13

    Topics: Animals; Anti-Inflammatory Agents; Cell Line; Concanavalin A; Diosgenin; Humans; Interleukin-2; Interleukin-8; Jurkat Cells; Lipopolysaccharides; Macrophages; Mice; Nitric Oxide; Plant Extracts; Solanine; Solanum tuberosum

2013
Glycoalkaloid and calystegine levels in table potato cultivars subjected to wounding, light, and heat treatments.
    Journal of agricultural and food chemistry, 2013, Jun-19, Volume: 61, Issue:24

    Topics: Crops, Agricultural; Food Handling; Food Quality; Glycosylation; Hot Temperature; Light; Mechanical Phenomena; Nortropanes; Plant Tubers; Solanaceous Alkaloids; Solanine; Solanum tuberosum; Species Specificity; Stereoisomerism; Sweden; Up-Regulation

2013
Synergistic cytotoxicity induced by α-solanine and α-chaconine.
    Food chemistry, 2013, Nov-15, Volume: 141, Issue:2

    Topics: Animals; Biological Transport; Cell Line, Tumor; Cell Membrane; Cell Survival; NAD; Rats; Solanine; Solanum tuberosum; Toxins, Biological

2013
Effect of genotype and environment on the glycoalkaloid content of rare, heritage, and commercial potato varieties.
    Journal of food science, 2014, Volume: 79, Issue:5

    Topics: Agriculture; Diet; Environment; Food Safety; Genotype; Humans; Plant Tubers; Solanine; Solanum tuberosum

2014
Detection of glycoalkaloids using disposable biosensors based on genetically modified enzymes.
    Analytical biochemistry, 2014, Jul-15, Volume: 457

    Topics: Acetylcholinesterase; Biosensing Techniques; Butyrylcholinesterase; Disposable Equipment; Genetic Engineering; Solanine; Solanum tuberosum

2014
[Determination of alpha-solanine, alpha-chaconine and solanidine in plasma and urine by ultra-performance liquid chromatography-triple quadrupole mass spectrometry].
    Se pu = Chinese journal of chromatography, 2014, Volume: 32, Issue:6

    Topics: Chromatography, High Pressure Liquid; Diosgenin; Humans; Solanine; Solid Phase Extraction; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry

2014
α-Chaconine isolated from a Solanum tuberosum L. cv Jayoung suppresses lipopolysaccharide-induced pro-inflammatory mediators via AP-1 inactivation in RAW 264.7 macrophages and protects mice from endotoxin shock.
    Chemico-biological interactions, 2015, Jun-25, Volume: 235

    Topics: Animals; Cell Line; Cyclooxygenase 2; Endotoxins; Inflammation; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Macrophages; Male; MAP Kinase Kinase 4; MAP Kinase Kinase 7; Mice; Mice, Inbred C57BL; Phosphorylation; Solanine; Solanum tuberosum; Transcription Factor AP-1; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha

2015
Recovery of steroidal alkaloids from potato peels using pressurized liquid extraction.
    Molecules (Basel, Switzerland), 2015, May-13, Volume: 20, Issue:5

    Topics: Alkaloids; Diosgenin; Methanol; Phytochemicals; Solanaceous Alkaloids; Solanine; Solanum tuberosum; Solid Phase Extraction

2015
Characterization and Transcriptional Profile of Genes Involved in Glycoalkaloid Biosynthesis in New Varieties of Solanum tuberosum L.
    Journal of agricultural and food chemistry, 2016, Feb-03, Volume: 64, Issue:4

    Topics: Alkaloids; Biosynthetic Pathways; Plant Proteins; Plant Tubers; Promoter Regions, Genetic; Solanine; Solanum tuberosum; Transcription, Genetic

2016
Antifungal activity of secondary plant metabolites from potatoes (Solanum tuberosum L.): Glycoalkaloids and phenolic acids show synergistic effects.
    Journal of applied microbiology, 2016, Volume: 120, Issue:4

    Topics: Antifungal Agents; Caffeic Acids; Diosgenin; Fungi; Microbial Sensitivity Tests; Phenols; Solanine; Solanum tuberosum

2016
Impact of light-exposure on the metabolite balance of transgenic potato tubers with modified glycoalkaloid biosynthesis.
    Food chemistry, 2016, Jun-01, Volume: 200

    Topics: Chlorophyll; Chromatography, Liquid; Gas Chromatography-Mass Spectrometry; Light; Mass Spectrometry; Plant Tubers; Plants, Genetically Modified; Solanaceous Alkaloids; Solanine; Solanum tuberosum

2016
Effect of Drying Methods on the Steroidal Alkaloid Content of Potato Peels, Shoots and Berries.
    Molecules (Basel, Switzerland), 2016, Mar-25, Volume: 21, Issue:4

    Topics: Alkaloids; Chromatography, High Pressure Liquid; Freeze Drying; Fruit; Phytosterols; Plant Shoots; Solanine; Solanum tuberosum; Tandem Mass Spectrometry

2016
Solanum tuberosum and Lycopersicon esculentum Leaf Extracts and Single Metabolites Affect Development and Reproduction of Drosophila melanogaster.
    PloS one, 2016, Volume: 11, Issue:5

    Topics: Animals; Body Size; Drosophila melanogaster; Female; Male; Pest Control, Biological; Plant Extracts; Plant Leaves; Reproduction; Solanine; Solanum lycopersicum; Solanum tuberosum; Tomatine

2016
Two Cytochrome P450 Monooxygenases Catalyze Early Hydroxylation Steps in the Potato Steroid Glycoalkaloid Biosynthetic Pathway.
    Plant physiology, 2016, Volume: 171, Issue:4

    Topics: Biosynthetic Pathways; Breeding; Crops, Agricultural; Cytochrome P-450 Enzyme System; Gene Silencing; Hydroxylation; Phenotype; Phytosterols; Plant Proteins; Plant Tubers; Solanine; Solanum tuberosum

2016
Isolation and chemoenzymatic treatment of glycoalkaloids from green, sprouting and rotting Solanum tuberosum potatoes for solanidine recovery.
    Food chemistry, 2017, Apr-01, Volume: 220

    Topics: Animals; beta-Glucosidase; Chromatography, High Pressure Liquid; Diosgenin; Hydrogen-Ion Concentration; Periplaneta; Solanine; Solanum tuberosum

2017
The Impact of Steroidal Glycoalkaloids on the Physiology of Phytophthora infestans, the Causative Agent of Potato Late Blight.
    Molecular plant-microbe interactions : MPMI, 2017, Volume: 30, Issue:7

    Topics: Carbohydrate Sequence; Diosgenin; Fungal Proteins; Glycoside Hydrolases; Glycosylation; Host-Pathogen Interactions; Molecular Structure; Mycelium; Phytophthora infestans; Plant Diseases; Solanaceous Alkaloids; Solanine; Solanum lycopersicum; Solanum tuberosum; Steroids

2017
α-Chaconine and α-Solanine Inhibit RL95-2 Endometrium Cancer Cell Proliferation by Reducing Expression of Akt (Ser473) and ERα (Ser167).
    Nutrients, 2018, May-25, Volume: 10, Issue:6

    Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Down-Regulation; Endometrial Neoplasms; Estrogen Receptor alpha; Female; Humans; Inhibitory Concentration 50; Phosphorylation; Proto-Oncogene Proteins c-akt; Signal Transduction; Solanine; Time Factors

2018
Synthesis and insecticidal activities of novel solanidine derivatives.
    Pest management science, 2019, Volume: 75, Issue:3

    Topics: Animals; Aphids; Diosgenin; Fertility; Insecticides; Nymph; Solanine; Solanum tuberosum

2019
RNA Sequencing Reveals That Both Abiotic and Biotic Stress-Responsive Genes are Induced during Expression of Steroidal Glycoalkaloid in Potato Tuber Subjected to Light Exposure.
    Genes, 2019, 11-11, Volume: 10, Issue:11

    Topics: Disease Resistance; Exome Sequencing; Gene Expression Regulation, Plant; Light; Plant Tubers; RNA-Seq; Secondary Metabolism; Solanine; Solanum tuberosum; Stress, Physiological; Transcriptome

2019
Discovery of a Bacterial Gene Cluster for Deglycosylation of Toxic Potato Steroidal Glycoalkaloids α-Chaconine and α-Solanine.
    Journal of agricultural and food chemistry, 2020, Feb-05, Volume: 68, Issue:5

    Topics: Arthrobacter; Bacterial Proteins; Biotransformation; Glycosylation; Multigene Family; Phylogeny; Solanine; Solanum tuberosum

2020
Glyphosate-based herbicide has soil-mediated effects on potato glycoalkaloids and oxidative status of a potato pest.
    Chemosphere, 2020, Volume: 258

    Topics: Animals; Antioxidants; Coleoptera; Glutathione Transferase; Glycine; Glyphosate; Herbicides; Larva; Oxidation-Reduction; Oxidative Stress; Soil; Solanine; Solanum tuberosum

2020
The biosynthetic pathway of potato solanidanes diverged from that of spirosolanes due to evolution of a dioxygenase.
    Nature communications, 2021, 02-26, Volume: 12, Issue:1

    Topics: Amino Acid Sequence; Biosynthetic Pathways; Cholesterol; Dioxygenases; Gene Expression Regulation, Plant; Genes, Plant; Hydroxylation; Ketoglutaric Acids; Phylogeny; Plants, Genetically Modified; Secondary Metabolism; Solanine; Solanum lycopersicum; Solanum melongena; Solanum tuberosum; Tomatine

2021
Characterization of C-26 aminotransferase, indispensable for steroidal glycoalkaloid biosynthesis.
    The Plant journal : for cell and molecular biology, 2021, Volume: 108, Issue:1

    Topics: 4-Aminobutyrate Transaminase; Gene Editing; Hydroxylation; Ketocholesterols; Plant Proteins; Plant Tubers; Saponins; Solanine; Solanum tuberosum

2021
Maleic and L-tartaric acids as new anti-sprouting agents for potatoes during storage in comparison to other efficient sprout suppressants.
    Scientific reports, 2021, 10-08, Volume: 11, Issue:1

    Topics: Food Storage; Maleates; Plant Tubers; Solanine; Solanum tuberosum; Tartrates

2021
Solanaceae glycoalkaloids: α-solanine and α-chaconine modify the cardioinhibitory activity of verapamil.
    Pharmaceutical biology, 2022, Volume: 60, Issue:1

    Topics: Solanaceae; Solanine; Solanum tuberosum; Verapamil

2022