Page last updated: 2024-08-25

sofosbuvir and tenofovir

sofosbuvir has been researched along with tenofovir in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's10 (58.82)24.3611
2020's7 (41.18)2.80

Authors

AuthorsStudies
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Bunnell, KL; Gallagher, MA; Glowacki, RC; Huhn, G; Osei, AM; Vibhakar, S1
Anania, FA; Pearlman, BL; Pillai, AA1
Shen, Y; Yan, B1
Bonfanti, P; Celesia, BM; De Socio, GV; Di Biagio, A; Maggi, P; Martinelli, C; Nicolini, LA; Quirino, T; Ricci, E; Squillace, N; Taramasso, L1
Brainard, DM; Ling, KHJ; Mathias, A; Mogalian, E; Osinusi, A; Shen, G; Stamm, LM1
Elfiky, AA; Ismail, AM1
Anderson, PL; Brainard, DM; Bushman, LR; Castillo-Mancilla, JR; Chung, RT; Fierer, DS; Hughes, MD; Kim, AY; Kiser, JJ; MacBrayne, CE; Marks, KM; Naggie, S; Peters, MG; Seifert, SM1
Easley, KA; Kalapila, AG; Kyle, AW; Michal, JL; Miller, LS; Patel, M; Rab, S1
Domalakes, E; He, L; Lee, GT; Mason, CW; Parrott, J; Pfeifer, E; Zhou, H1
Alexander, K; Anderson, PL; Blum, J; Brooks, KM; Bushman, LR; Castillo-Mancilla, JR; Ellison, L; Huntley, R; Kerr, BJ; Kiser, JJ; MacBrayne, CE; MaWhinney, S1
Wahid, B1
Chung, RT; Holmes, JA1
Applin, S; Asmuth, DM; Cox, S; Das, M; Goldstein, D; Guyer, B; Haubrich, RH; Hinestrosa, F; Huhn, GD; Jain, MK; Jiang, S; Nguyen-Cleary, T; Piontkowsky, D; Ramgopal, M; Rossaro, L; Ryu, JH; Slim, J1
Anderson, PL; Blum, J; Brooks, KM; Bushman, LR; Castillo-Mancilla, JR; Cendali, F; Choi, YJ; Gomez, J; Haas, H; Ibrahim, ME; Johnson, B; Kiser, JJ; MaWhinney, S; Morrow, M; Roon, L; Rowan, SE; Wyles, DL; Zheng, JH1
Abdel Alem, S; Abdelbary, MS; Cordie, A; El Garhy, N; El Khateeb, E; Elsharkawy, A; Esmat, G; Fouad, R; Khalil, M1
Cecka, F; Cerveny, L; Dusek, T; Halodova, V; Huliciak, M; Kocova-Vlckova, H; Lhotska, I; Staud, F; Vokral, I1

Reviews

1 review(s) available for sofosbuvir and tenofovir

ArticleYear
New approaches in viraemic organ transplantation and antiviral therapies.
    Nature reviews. Gastroenterology & hepatology, 2020, Volume: 17, Issue:2

    Topics: Aminoisobutyric Acids; Antiviral Agents; Carbamates; Carcinoma, Hepatocellular; Cyclopropanes; Guanine; Hepatitis B, Chronic; Hepatitis C, Chronic; Heterocyclic Compounds, 4 or More Rings; Humans; Lactams, Macrocyclic; Leucine; Liver Neoplasms; Liver Transplantation; Macrocyclic Compounds; Proline; Quinoxalines; Salvage Therapy; Sofosbuvir; Sulfonamides; Tenofovir; Transplants

2020

Trials

3 trial(s) available for sofosbuvir and tenofovir

ArticleYear
Drug-Drug Interaction Studies Between Hepatitis C Virus Antivirals Sofosbuvir/Velpatasvir and Boosted and Unboosted Human Immunodeficiency Virus Antiretroviral Regimens in Healthy Volunteers.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2018, 08-31, Volume: 67, Issue:6

    Topics: Adolescent; Adult; Anti-HIV Agents; Carbamates; Cross-Over Studies; Drug Interactions; Female; Healthy Volunteers; Heterocyclic Compounds, 4 or More Rings; Humans; Male; Middle Aged; Sofosbuvir; Tenofovir; Young Adult

2018
Effects of sofosbuvir-based hepatitis C treatment on the pharmacokinetics of tenofovir in HIV/HCV-coinfected individuals receiving tenofovir disoproxil fumarate.
    The Journal of antimicrobial chemotherapy, 2018, 08-01, Volume: 73, Issue:8

    Topics: Adenine; Adult; Antiviral Agents; Benzimidazoles; Coinfection; Drug Interactions; Fluorenes; Hepatitis C; HIV Infections; Humans; Male; Middle Aged; Organophosphates; Ribavirin; Sofosbuvir; Tenofovir; Uridine Monophosphate

2018
HIV/HCV therapy with ledipasvir/sofosbuvir after randomized switch to emtricitabine-tenofovir alafenamide-based single-tablet regimens.
    PloS one, 2020, Volume: 15, Issue:1

    Topics: Adenine; Adult; Aged; Alanine; Benzimidazoles; Coinfection; Drug Combinations; Drug Resistance, Viral; Emtricitabine; Female; Fluorenes; Hepacivirus; Hepatitis C; HIV Infections; HIV-1; Humans; Male; Middle Aged; RNA, Viral; Sofosbuvir; Tenofovir

2020

Other Studies

13 other study(ies) available for sofosbuvir and tenofovir

ArticleYear
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Nephrotoxicity Associated with Concomitant Use of Ledipasvir-Sofosbuvir and Tenofovir in a Patient with Hepatitis C Virus and Human Immunodeficiency Virus Coinfection.
    Pharmacotherapy, 2016, Volume: 36, Issue:9

    Topics: Antiviral Agents; Benzimidazoles; Coinfection; Drug Therapy, Combination; Female; Fluorenes; Hepatitis C; HIV Infections; Humans; Kidney; Middle Aged; Sofosbuvir; Tenofovir

2016
Caution: Reactivation of Hepatitis B during Hepatitis C Treatment with Direct-Acting Antiviral Therapy.
    The American journal of gastroenterology, 2016, Volume: 111, Issue:12

    Topics: Aged; Antiviral Agents; Drug Therapy, Combination; Guanine; Hepatitis B, Chronic; Hepatitis C, Chronic; Humans; Male; Middle Aged; Simeprevir; Sofosbuvir; Tenofovir; Viral Load; Virus Activation

2016
Covalent inhibition of carboxylesterase-2 by sofosbuvir and its effect on the hydrolytic activation of tenofovir disoproxil.
    Journal of hepatology, 2017, Volume: 66, Issue:3

    Topics: Anti-HIV Agents; Antiviral Agents; Carboxylesterase; Carboxylic Ester Hydrolases; Cell Fractionation; Chromatography, Liquid; Drug Interactions; Humans; Hydrolysis; Kidney; Microsomes, Liver; Sofosbuvir; Tenofovir

2017
Co-administration of tenofovir plus protease inhibitor based antiretroviral therapy during sofosbuvir/ledipasvir treatment for HCV infection: Much Ado About Nothing?
    Clinics and research in hepatology and gastroenterology, 2017, Volume: 41, Issue:5

    Topics: Antiviral Agents; Benzimidazoles; Drug Administration Schedule; Drug Therapy, Combination; Evidence-Based Medicine; Fluorenes; Hepatitis C; Humans; Sofosbuvir; Tenofovir; Treatment Outcome

2017
Molecular docking revealed the binding of nucleotide/side inhibitors to Zika viral polymerase solved structures.
    SAR and QSAR in environmental research, 2018, Volume: 29, Issue:5

    Topics: Antiviral Agents; Drug Design; Models, Molecular; Molecular Docking Simulation; Nucleosides; Nucleotides; Ribavirin; RNA-Dependent RNA Polymerase; Sofosbuvir; Tenofovir; Zika Virus

2018
Incidence of Acute Kidney Injury in Patients Coinfected with HIV and Hepatitis C Virus Receiving Tenofovir Disoproxil Fumarate and Ledipasvir/Sofosbuvir in a Real-World, Urban, Ryan White Clinic.
    AIDS research and human retroviruses, 2018, Volume: 34, Issue:8

    Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Antiviral Agents; Benzimidazoles; Coinfection; Female; Fluorenes; Georgia; Hepatitis C, Chronic; HIV Infections; Humans; Incidence; Male; Middle Aged; Retrospective Studies; Reverse Transcriptase Inhibitors; Risk Factors; Sofosbuvir; Tenofovir; Young Adult

2018
Regulation of human placental drug transporters in HCV infection and their influence on direct acting antiviral medications.
    Placenta, 2018, Volume: 69

    Topics: Antiviral Agents; ATP-Binding Cassette Transporters; Biological Transport; Female; Guanine; Hepatitis C; Humans; Placenta; Pregnancy; Sofosbuvir; Solute Carrier Proteins; Tenofovir; Trophoblasts

2018
Increased tenofovir monoester concentrations in patients receiving tenofovir disoproxil fumarate with ledipasvir/sofosbuvir.
    The Journal of antimicrobial chemotherapy, 2019, 08-01, Volume: 74, Issue:8

    Topics: Adenine; Adolescent; Adult; Antiviral Agents; Benzimidazoles; Blood Chemical Analysis; Chromatography, Liquid; Drug Interactions; Female; Fluorenes; Hepatitis C, Chronic; HIV Infections; Humans; Male; Middle Aged; Phosphorous Acids; Sofosbuvir; Tandem Mass Spectrometry; Tenofovir; Young Adult

2019
Successful treatment of HBV, HCV, & HEV, with 12-week long use of tenofovir, sofosbuvir, daclatasvir, and ribavirin: A case report.
    Journal of infection and public health, 2020, Volume: 13, Issue:1

    Topics: Aged; Antiviral Agents; Asthma; Carbamates; Coinfection; Diabetes Complications; Drug Administration Schedule; Drug Therapy, Combination; Hepatitis B; Hepatitis C, Chronic; Hepatitis E; Humans; Imidazoles; Male; Pyrrolidines; Ribavirin; Sofosbuvir; Tenofovir; Treatment Outcome; Valine; Viral Load

2020
Pharmacokinetics and renal safety of tenofovir alafenamide with boosted protease inhibitors and ledipasvir/sofosbuvir.
    The Journal of antimicrobial chemotherapy, 2020, 11-01, Volume: 75, Issue:11

    Topics: Adenine; Alanine; Anti-HIV Agents; Benzimidazoles; Fluorenes; HIV Infections; Humans; Protease Inhibitors; Sofosbuvir; Tenofovir

2020
Serial changes in renal indices in chronic HCV patients with and without HIV co-infection receiving sofosbuvir and tenofovir-based therapies.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 2023, 04-03, Volume: 117, Issue:4

    Topics: Antiviral Agents; Coinfection; Hepacivirus; Hepatitis C; Hepatitis C, Chronic; HIV Infections; Humans; Prospective Studies; Sofosbuvir; Tenofovir

2023
Effect of P-glycoprotein and Cotreatment with Sofosbuvir on the Intestinal Permeation of Tenofovir Disoproxil Fumarate and Tenofovir Alafenamide Fumarate.
    Pharmaceutical research, 2023, Volume: 40, Issue:9

    Topics: Adenine; Alanine; Anti-HIV Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Fumarates; HIV Infections; Humans; Sofosbuvir; Tenofovir

2023