Page last updated: 2024-08-25

sofosbuvir and psi 6130

sofosbuvir has been researched along with psi 6130 in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Berke, JM; Fanning, G; Hu, L; Jonckers, TH; Lachau-Durand, S; Leclercq, L; Lin, TI; Nilsson, M; Raboisson, P; Rosenquist, Å; Samuelsson, B; Simmen, K; Stoops, B; Tahri, A; Van Hoof, S; Vandekerckhove, L; Vandyck, K; Vijgen, L1
Cao, L; Nie, Q; Shang, L; Yin, Z; Zeng, D; Zhang, R1
Berger, R; Conrad, JC; MacMillan, DW; Peifer, M; Shurtleff, VW1
Bao, H; Bourne, N; Espiritu, C; Frick, DN; Furman, PA; Heck, JA; Julander, JG; Keilman, M; Lam, AM; Morrey, JD; Murakami, E; Nagarathnam, D; Niu, C; Otto, MJ; Ross, BS; Smee, DF; Sofia, MJ; Steuer, HM; Wang, P; Zennou, V1

Other Studies

4 other study(ies) available for sofosbuvir and psi 6130

ArticleYear
Nucleotide prodrugs of 2'-deoxy-2'-spirooxetane ribonucleosides as novel inhibitors of the HCV NS5B polymerase.
    Journal of medicinal chemistry, 2014, Mar-13, Volume: 57, Issue:5

    Topics: Animals; Antiviral Agents; Area Under Curve; Drug Evaluation, Preclinical; Enzyme Inhibitors; Hepacivirus; Humans; Magnetic Resonance Spectroscopy; Prodrugs; Rats; Rats, Sprague-Dawley; Ribonucleosides; Viral Nonstructural Proteins

2014
Discovery of 2'-α-C-Methyl-2'-β-C-fluorouridine Phosphoramidate Prodrugs as Inhibitors of Hepatitis C Virus.
    ACS medicinal chemistry letters, 2016, Dec-08, Volume: 7, Issue:12

    Topics:

2016
A general and enantioselective approach to pentoses: a rapid synthesis of PSI-6130, the nucleoside core of sofosbuvir.
    Journal of the American Chemical Society, 2014, Apr-23, Volume: 136, Issue:16

    Topics: Chemistry Techniques, Synthetic; Deoxycytidine; Kinetics; Pentoses; Sofosbuvir; Stereoisomerism; Substrate Specificity; Uridine Monophosphate

2014
PSI-7851, a pronucleotide of beta-D-2'-deoxy-2'-fluoro-2'-C-methyluridine monophosphate, is a potent and pan-genotype inhibitor of hepatitis C virus replication.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:8

    Topics: Amides; Antiviral Agents; Cell Line, Tumor; Deoxyuracil Nucleotides; Enzyme Inhibitors; Genotype; Hepacivirus; Humans; Phosphoric Acids; Prodrugs; Replicon; RNA-Dependent RNA Polymerase; RNA, Viral; Viral Nonstructural Proteins; Virus Replication

2010