sofosbuvir has been researched along with 5-formylcytosine in 81 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 67 (82.72) | 24.3611 |
2020's | 14 (17.28) | 2.80 |
Authors | Studies |
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Collins, LB; Dai, Q; He, C; Ito, S; Shen, L; Swenberg, JA; Wu, SC; Zhang, Y | 1 |
Gong, Z; Zhu, JK | 1 |
Kohli, RM; Nabel, CS | 1 |
Dai, Q; He, C; Inoue, A; Shen, L; Zhang, Y | 1 |
Begley, MC; Drohat, AC; Maiti, A; Manvilla, BA; Toth, EA | 1 |
Chong, J; He, C; Kellinger, MW; Lu, XY; Song, CX; Wang, D | 1 |
Cheng, X; Hashimoto, H; Zhang, X | 1 |
Bapat, B; Olkhov-Mitsel, E | 1 |
Jin, P; Yao, B | 1 |
Armwood, CJ; Drohat, AC; Lee, JK; Maiti, A; Michelson, AZ | 1 |
Feng, YQ; Liu, YL; Vargas, M; Wang, Y; Xing, XW; Yuan, BF; Zhou, X | 1 |
An, R; Ming, GL; Shin, J; Song, H; Weng, YL | 1 |
Cheng, X; Corrêa, IR; Dai, N; Fu, ZQ; Hashimoto, H; Pais, JE; Saleh, L; Zhang, X; Zheng, Y | 1 |
Hu, D; Jin, L; Lü, J; Wang, W | 1 |
Rao, A; Tsagaratou, A | 1 |
Aravind, L; Chen, W; Dai, Q; Fu, Y; He, C; Hu, J; Iyer, LM; Wang, G; Yu, M; Zhang, L | 1 |
Aluru, N; Ci, W; Duan, J; Gao, X; He, C; Huang, X; Li, G; Li, W; Liu, J; Lu, X; Tang, F; Wang, L; Yang, L; Zhang, J; Zhou, Q; Zhu, W | 1 |
He, C; Shen, L; Song, CX; Zhang, Y | 1 |
Collins, LB; Hanaoka, F; Ito, S; Iwai, S; Kanao, R; Koseki, H; Kuraoka, I; Masuda, Y; Masutani, C; Shibata, M; Shibutani, T; Swenberg, JA; Toda, M; Urabe, M | 1 |
Huang, Y; Rao, A | 1 |
Hahn, MA; Pfeifer, GP; Szabó, PE | 1 |
Shen, L; Wu, H; Wu, X; Zhang, Y | 1 |
Doré, LC; Han, D; He, C; Lu, X; Song, CX; Zhang, LS; Zhao, BS | 1 |
Banerjee, S; Brooks, S; Egli, M; Eichman, BF; Joachimiak, A; Nocek, B; Pallan, PS; Stone, MP; Szulik, MW; Voehler, M | 1 |
Yuan, BF | 1 |
Golla, JP; Sathyanarayana, BK; Sayeed, SK; Vinson, C; Zhao, J | 1 |
Gu, TP; Guo, F; Li, BZ; Li, Z; Liu, X; Schär, P; Shen, JZ; Tang, F; Wang, H; Weber, AR; Xie, ZG; Xu, GL; Yin, R | 1 |
Chevassut, T; Cho, IH; Choudhury, SR; Chowdhury, B; Cooper, B; Cui, Y; Irudayaraj, J; Lossie, AC; McGovern, A | 1 |
Ito, S; Kuraoka, I | 1 |
Chan, WY; Chung, JP; Kong, GW; Lee, TL; Qian, Y; Tang, NL; Tu, J | 1 |
Chen, L; Chong, J; Fu, XD; He, C; Li, H; Lu, X; Wang, D; Wang, L; Xiao, R; Xu, L; Zhou, Y | 1 |
Wu, H; Zhang, Y | 1 |
Han, D; He, C; Jiang, X; Liu, M; Lu, X; Sun, Z; Xia, B; Xie, W; Yi, C; Yin, Q; Zeng, H; Zhou, A | 1 |
Dai, Q; Han, D; He, C; Peng, CS; Sanstead, PJ; Tokmakoff, A | 1 |
Gackowski, D; Modrzejewska, M; Olinski, R; Starczak, M; Zarakowska, E | 1 |
Aksimentiev, A; Dai, Q; Ha, T; He, C; Ngo, TT; Yoo, J; Zhang, Q | 1 |
He, Y; Jin, P; Tang, B; Wang, Z | 1 |
Incarnato, D; Krepelova, A; Neri, F; Oliviero, S; Parlato, C | 1 |
Abbes, S; Bernard, OA; Cabagnols, X; Della Valle, V; Ishchenko, AA; Mahfoudhi, E; Plo, I; Rameau, P; Saparbaev, M; Secardin, L; Talhaoui, I; Vainchenker, W | 1 |
Chang, PM; Chou, NH; Kang, CH; Lam, HC; Li, GC; Liu, SI; Tsai, CY; Tsai, KW; Tu, YT; Wang, KC | 1 |
Pfeifer, GP; Song, J | 1 |
Han, YW; Harada, Y; Kizaki, S; Li, Y; Sugiyama, H; Suzuki, Y; Zou, T | 1 |
Agris, PF; Basanta-Sanchez, M; Huang, Y; Li, M; Liu, Z; Sheng, J; Shi, X; Wang, R; Ye, X; Zhou, Y | 1 |
Coey, CT; Drohat, AC; Flowers, JW; Greenberg, MM; Pidugu, LS; Pozharski, E | 1 |
Shimbo, T; Wade, PA | 1 |
Cheng, X; Hong, S | 1 |
Foksinski, M; Gackowski, D; Gawronski, M; Modrzejewska, M; Olinski, R; Rzeszowska-Wolny, J; Skonieczna, M; Starczak, M; Zarakowska, E | 1 |
Klungland, A; Robertson, AB | 1 |
Chen, Z; Guo, L; He, J; Li, Y; Luo, M; Shi, X | 1 |
Bronner, C; Dimitrov, S; Gras, SL; Hamiche, A; Ibrahim, A; Jost, B; Menoni, H; Papin, C; Stoll, I; Velt, A | 1 |
Bieńkiewicz, A; Bryś, M; Ciesielski, P; Cwonda, Ł; Forma, E; Jóźwiak, P; Krześlak, A; Szczepaniec, S; Wójcik-Krowiranda, K | 1 |
Bochtler, M; Mierzejewska, K; Slyvka, A | 1 |
Allgayer, J; Carell, T; Geier, N; Khobta, A; Kitsera, N; Parsa, E; Rossa, M | 1 |
Brown, T; Hardwick, JS; Lane, AN | 1 |
Coey, CT; Drohat, AC | 1 |
Giehr, P; Kyriakopoulos, C; Lepikhov, K; Wallner, S; Walter, J; Wolf, V | 1 |
Borre, M; Høyer, S; Lynnerup, AS; Storebjerg, TM; Strand, SH; Sørensen, KD; Ørntoft, TF | 1 |
Baranov, VS; Chiryaeva, OG; Efimova, OA; Gzgzyan, AM; Kogan, IY; Koltsova, AS; Krapivin, MI; Mekina, ID; Pendina, AA; Petrovskaia-Kaminskaia, AV; Tikhonov, AV | 1 |
Cao, Z; Chen, Z; Gao, D; Khan, IM; Luo, L; Tong, X; Wang, Y; Xu, T; Zhang, D; Zhang, L; Zhang, M; Zhang, Y | 1 |
Wang, P; Yan, Y; Yu, W; Zhang, H | 1 |
Bian, K; Chen, F; Drennan, CL; Essigmann, JM; Jost, M; Lenz, SAP; Li, D; Qi, R; Tang, Q; Wetmore, SD | 1 |
Daumann, LJ; Jonasson, NSW | 1 |
Cao, LL; Jia, M; Liu, H; Pei, L; Wang, H; Yue, Z | 1 |
Hassan, HM; Torchia, J; Underhill, TM | 1 |
Cai, C; Chen, D; Chen, J; Dai, Z; Liu, SY; Ma, Y; Mo, M; Wang, Y; Xu, Y; Zhang, J; Zhang, L; Zhang, Y; Zou, X | 1 |
Yu, Y; Yuan, F; Zhang, XH; Zhang, XX; Zhao, MZ; Zhou, YL | 1 |
Abdelhamid, MAS; Ehiabor, MO; Grigg, MC; Irving, K; Smith, NM; Waller, ZAE; Wright, EP | 1 |
Abakir, A; Fossdal, CG; Gackowski, D; Krutovsky, KV; Olinski, R; Ruzov, A; Starczak, M; Viejo, M; Yakovlev, IA | 1 |
Gackowski, D; Gawronski, M; Olinski, R; Starczak, M | 1 |
Szabó, PE; Zeng, TB | 1 |
Abakir, A; Ruzov, A | 1 |
Gering, M; Jessop, P | 1 |
Fossdal, CG; Viejo, M; Yakovlev, I | 1 |
Celik-Uzuner, S | 1 |
Abakir, A; Alenezi, F; Ruzov, A | 1 |
Assad, N; Durell, S; Ray, S; Tillo, D; Ufot, A; Vinson, C | 1 |
DeNizio, JE; Dow, BJ; Drohat, AC; Ghanty, U; Kohli, RM; Serrano, JC | 1 |
Eden, HE; Huang, Z; Robertson, KD; Rothbart, SB; Tiedemann, RL | 1 |
Bellacosa, A; Georges, RO; González-Avalos, E; Lio, CJ; Nakayama, T; Onodera, A; Rao, A | 1 |
Bai, L; Ding, C; Feng, J; Gong, T; Li, J; Li, X; Li, Z; Liu, M; Lyu, J; Qin, J; Qin, Z; Wang, Y; Yang, G; Yang, W | 1 |
Carell, T; Khobta, A; Müller, N; Ponkkonen, E | 1 |
16 review(s) available for sofosbuvir and 5-formylcytosine
Article | Year |
---|---|
Strategies for discovery and validation of methylated and hydroxymethylated DNA biomarkers.
Topics: 5-Methylcytosine; Animals; CpG Islands; Cytosine; Disease; DNA Methylation; Epigenesis, Genetic; Gene Expression Profiling; Genetic Markers; Humans; Restriction Mapping; Sequence Analysis, DNA | 2012 |
Cytosine modifications in neurodevelopment and diseases.
Topics: 5-Methylcytosine; Cytosine; DNA Methylation; DNA-Cytosine Methylases; Humans; Models, Molecular; Nervous System Diseases; Neurogenesis | 2014 |
DNA modifications and neurological disorders.
Topics: 5-Methylcytosine; Brain; Cytosine; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation; Humans; Nervous System Diseases; Neurons | 2013 |
Mechanism and function of oxidative reversal of DNA and RNA methylation.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA; DNA Methylation; Escherichia coli; Gene Expression Regulation; Genome; Germ Cells; HEK293 Cells; Humans; Methylation; Mice; Neoplasms; Oxygen; RNA; Stem Cells; Transcriptome | 2014 |
Connections between TET proteins and aberrant DNA modification in cancer.
Topics: 5-Methylcytosine; Azacitidine; Cytosine; Decitabine; Dioxygenases; DNA Methylation; DNA Modification Methylases; DNA-Binding Proteins; Hematologic Neoplasms; Humans; Isocitrate Dehydrogenase; Mixed Function Oxygenases; Molecular Targeted Therapy; Mutation; Neoplasms; Proto-Oncogene Proteins; Small Molecule Libraries | 2014 |
5-Hydroxymethylcytosine: a stable or transient DNA modification?
Topics: 5-Methylcytosine; Animals; Brain; Cytosine; DNA Methylation; DNA Replication; DNA-Binding Proteins; Humans | 2014 |
5-methylcytosine and its derivatives.
Topics: 5-Methylcytosine; Chromatography, Thin Layer; Cytosine; DNA Methylation; Electrophoresis, Capillary; Endonucleases; Epigenesis, Genetic; Gas Chromatography-Mass Spectrometry; Humans; Microarray Analysis; Oxidation-Reduction; Polymerase Chain Reaction; Sulfites | 2014 |
Epigenetic modifications in DNA could mimic oxidative DNA damage: A double-edged sword.
Topics: 5-Methylcytosine; Base Pair Mismatch; CpG Islands; Cytosine; Deamination; DNA Damage; DNA Methylation; DNA Repair; Epigenesis, Genetic; Gene Expression; Humans; Molecular Mimicry; Oxidation-Reduction; Thymine DNA Glycosylase | 2015 |
DNA methylation dynamics in neurogenesis.
Topics: 5-Methylcytosine; Animals; Cell Differentiation; Cytosine; DNA Methylation; Embryo, Mammalian; Embryonic Stem Cells; Epigenesis, Genetic; Histones; Humans; Mammals; Neurogenesis | 2016 |
Are there specific readers of oxidized 5-methylcytosine bases?
Topics: 5-Methylcytosine; Animals; Cytosine; DNA; DNA-Binding Proteins; Humans | 2016 |
Proteins That Read DNA Methylation.
Topics: 5-Methylcytosine; Adenine; Cytosine; DNA; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Protein Domains | 2016 |
DNA Base Flipping: A General Mechanism for Writing, Reading, and Erasing DNA Modifications.
Topics: 5-Methylcytosine; Adenine; Cytosine; DNA; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Eukaryota; Prokaryotic Cells; Protein Domains | 2016 |
Oxidized C5-methyl cytosine bases in DNA: 5-Hydroxymethylcytosine; 5-formylcytosine; and 5-carboxycytosine.
Topics: 5-Methylcytosine; Animals; Carcinogenesis; Cell Self Renewal; Cytosine; DNA; DNA Methylation; DNA Repair; Humans; Oxidation-Reduction; Transcription, Genetic | 2017 |
Decreased 5-hydroxymethylcytosine levels correlate with cancer progression and poor survival: a systematic review and meta-analysis.
Topics: 5-Methylcytosine; Cytosine; DNA Methylation; Humans; Lymphatic Metastasis; Neoplasms; Prognosis | 2017 |
Epigenetic Modifications of Cytosine: Biophysical Properties, Regulation, and Function in Mammalian DNA.
Topics: 5-Methylcytosine; Animals; Crystallography, X-Ray; Cytosine; Dioxygenases; DNA; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Humans; Mammals; Models, Molecular; Nucleic Acid Conformation | 2018 |
Role of ten-eleven translocation proteins and 5-hydroxymethylcytosine in hepatocellular carcinoma.
Topics: 5-Methylcytosine; Animals; Biomarkers, Tumor; Carcinoma, Hepatocellular; Cytosine; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Down-Regulation; Epigenesis, Genetic; Humans; Liver Neoplasms; MicroRNAs; Mixed Function Oxygenases; Proto-Oncogene Proteins; RNA Processing, Post-Transcriptional; Transcription, Genetic | 2019 |
65 other study(ies) available for sofosbuvir and 5-formylcytosine
Article | Year |
---|---|
Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine.
Topics: 5-Methylcytosine; Animals; Cell Line; Cytosine; Dioxygenases; DNA; DNA Methylation; DNA-Binding Proteins; Embryonic Stem Cells; Humans; Mice; Oxidation-Reduction; Proto-Oncogene Proteins; Recombinant Fusion Proteins | 2011 |
Active DNA demethylation by oxidation and repair.
Topics: Animals; Cytosine; DNA Replication; Embryonic Development; Male | 2011 |
Molecular biology. Demystifying DNA demethylation.
Topics: 5-Methylcytosine; Animals; Cytosine; Dioxygenases; DNA; DNA Methylation; DNA-Binding Proteins; Embryonic Stem Cells; Mice; Oxidation-Reduction; Proto-Oncogene Proteins; Thymine DNA Glycosylase | 2011 |
Generation and replication-dependent dilution of 5fC and 5caC during mouse preimplantation development.
Topics: 5-Methylcytosine; Animals; Antibodies; Cytosine; DNA Replication; DNA-Directed DNA Polymerase; Embryonic Development; Immunohistochemistry; Male; Mice | 2011 |
Crystal structure of human methyl-binding domain IV glycosylase bound to abasic DNA.
Topics: 5-Methylcytosine; Adenine; Binding Sites; Catalytic Domain; CpG Islands; Crystallography, X-Ray; Cytosine; DNA; Endodeoxyribonucleases; Furans; Guanine; Humans; Protein Conformation; Substrate Specificity | 2012 |
5-formylcytosine and 5-carboxylcytosine reduce the rate and substrate specificity of RNA polymerase II transcription.
Topics: Amino Acid Sequence; Base Sequence; Catalytic Domain; Cytosine; DNA; DNA, Fungal; Epigenesis, Genetic; Humans; Kinetics; Molecular Sequence Data; RNA; RNA Polymerase II; RNA, Fungal; Saccharomyces cerevisiae Proteins; Sequence Homology, Amino Acid; Substrate Specificity; Transcription, Genetic | 2012 |
Selective excision of 5-carboxylcytosine by a thymine DNA glycosylase mutant.
Topics: Cytosine; DNA; DNA Repair; Humans; Hydrogen-Ion Concentration; Mutagenesis; Mutation; Substrate Specificity; Thymine DNA Glycosylase | 2013 |
Divergent mechanisms for enzymatic excision of 5-formylcytosine and 5-carboxylcytosine from DNA.
Topics: Cytosine; DNA; Hydrogen-Ion Concentration; Models, Molecular; Molecular Structure; Quantum Theory; Thymine DNA Glycosylase | 2013 |
Mutagenic and cytotoxic properties of oxidation products of 5-methylcytosine revealed by next-generation sequencing.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA Methylation; Escherichia coli; High-Throughput Nucleotide Sequencing; Oxidation-Reduction; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2013 |
Structure of a Naegleria Tet-like dioxygenase in complex with 5-methylcytosine DNA.
Topics: 5-Methylcytosine; Amino Acid Sequence; Animals; Catalytic Domain; Conserved Sequence; Crystallography, X-Ray; Cytosine; Dioxygenases; DNA; DNA-Binding Proteins; Escherichia coli Proteins; HEK293 Cells; Humans; Hydrogen Bonding; Mice; Mixed Function Oxygenases; Models, Molecular; Molecular Sequence Data; Naegleria; Proto-Oncogene Proteins; Structural Homology, Protein; Structure-Activity Relationship; Substrate Specificity | 2014 |
A new insight into the 5-carboxycytosine and 5-formylcytosine under typical bisulfite conditions: a deamination mechanism study.
Topics: Cytosine; Deamination; Gases; Hydrogen Bonding; Isomerism; Models, Molecular; Solvents; Sulfites; Thermodynamics; Water | 2014 |
TET proteins and 5-methylcytosine oxidation in the immune system.
Topics: 5-Methylcytosine; Animals; Cytosine; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Gene Expression Profiling; Humans; Immunoprecipitation; Mice; Mixed Function Oxygenases; Oxidoreductases; Polymorphism, Single Nucleotide; Proto-Oncogene Proteins | 2013 |
A TET homologue protein from Coprinopsis cinerea (CcTET) that biochemically converts 5-methylcytosine to 5-hydroxymethylcytosine, 5-formylcytosine, and 5-carboxylcytosine.
Topics: 5-Methylcytosine; Agaricales; Cytosine; Dioxygenases; Fungal Proteins | 2014 |
Programming and inheritance of parental DNA methylomes in mammals.
Topics: 5-Methylcytosine; Animals; CpG Islands; Cytosine; DNA Methylation; Embryo, Mammalian; Embryonic Development; Female; Gene Expression Regulation, Developmental; Genomic Imprinting; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Promoter Regions, Genetic | 2014 |
Guanine- 5-carboxylcytosine base pairs mimic mismatches during DNA replication.
Topics: 5-Methylcytosine; Base Pairing; Cell Proliferation; Cytosine; DNA; DNA Mismatch Repair; DNA Replication; Epigenesis, Genetic; Guanine; Humans; Thymine DNA Glycosylase | 2014 |
Single-base resolution analysis of active DNA demethylation using methylase-assisted bisulfite sequencing.
Topics: 5-Methylcytosine; Animals; Base Sequence; Chromatin; Cytosine; DNA Methylation; DNA Repair; Embryonic Stem Cells; Gene Expression Regulation; High-Throughput Nucleotide Sequencing; Methyltransferases; Mice; Thymine DNA Glycosylase | 2014 |
Base-resolution maps of 5-formylcytosine and 5-carboxylcytosine reveal genome-wide DNA demethylation dynamics.
Topics: Animals; Base Composition; Base Sequence; Cell Line; Chromosome Mapping; Cytosine; DNA; DNA Methylation; Embryonic Stem Cells; Epigenesis, Genetic; Mice; Oxidation-Reduction; Sequence Analysis, DNA; Signal Transduction | 2015 |
Differential stabilities and sequence-dependent base pair opening dynamics of Watson-Crick base pairs with 5-hydroxymethylcytosine, 5-formylcytosine, or 5-carboxylcytosine.
Topics: 5-Methylcytosine; Cytosine; DNA; Oligonucleotides; Thymine DNA Glycosylase | 2015 |
C/EBPβ (CEBPB) protein binding to the C/EBP|CRE DNA 8-mer TTGC|GTCA is inhibited by 5hmC and enhanced by 5mC, 5fC, and 5caC in the CG dinucleotide.
Topics: 5-Methylcytosine; Animals; CCAAT-Enhancer-Binding Protein-beta; CCAAT-Enhancer-Binding Proteins; Crystallography, X-Ray; Cytosine; Cytosine Nucleotides; DNA; DNA Methylation; DNA-Binding Proteins; Embryonic Development; Nucleotide Motifs; Transcription Factors | 2015 |
Gadd45a promotes DNA demethylation through TDG.
Topics: Animals; Cell Cycle Proteins; Cytosine; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Embryonic Stem Cells; HEK293 Cells; Humans; Mice, Knockout; Nuclear Proteins; Proto-Oncogene Proteins; Thymine DNA Glycosylase; Transcriptional Activation | 2015 |
The hypomethylating agent Decitabine causes a paradoxical increase in 5-hydroxymethylcytosine in human leukemia cells.
Topics: 5-Methylcytosine; Azacitidine; Catalytic Domain; Chromatography, High Pressure Liquid; CpG Islands; Cytosine; Decitabine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA-Binding Proteins; Enzyme-Linked Immunosorbent Assay; HL-60 Cells; Humans; Immunohistochemistry; Leukemia, Myeloid, Acute; MCF-7 Cells; Microscopy, Fluorescence; Mixed Function Oxygenases; Protein Binding; Proto-Oncogene Proteins; Spectrometry, Fluorescence; Tandem Mass Spectrometry | 2015 |
Dynamic changes of DNA epigenetic marks in mouse oocytes during natural and accelerated aging.
Topics: 5-Methylcytosine; Aging; Animals; Cellular Senescence; Cyclohexenes; Cytosine; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Female; Histones; Injections, Intraperitoneal; Mice; Mice, Inbred C57BL; Oocytes; Ovary; Protein Isoforms; Proto-Oncogene Proteins; Thymine DNA Glycosylase; Vinyl Compounds | 2015 |
Molecular basis for 5-carboxycytosine recognition by RNA polymerase II elongation complex.
Topics: 5-Methylcytosine; Crystallography, X-Ray; Cytosine; DNA Methylation; DNA Repair; Epigenesis, Genetic; Hydrogen Bonding; Kinetics; RNA Polymerase II; Saccharomyces cerevisiae; Substrate Specificity; Templates, Genetic; Thymine DNA Glycosylase; Transcription Elongation, Genetic | 2015 |
Charting oxidized methylcytosines at base resolution.
Topics: 5-Methylcytosine; Animals; Cytosine; Dioxygenases; DNA; Epigenesis, Genetic; Gene Expression Regulation; Humans; Mammals; Oxidation-Reduction | 2015 |
Bisulfite-free, base-resolution analysis of 5-formylcytosine at the genome scale.
Topics: 5-Methylcytosine; Animals; Cell Line; CpG Islands; Cytosine; DNA Methylation; DNA Primers; Epigenomics; Gene Expression Regulation; Genome; Mice; Mice, Transgenic; Oligonucleotides; Oxygen; Polymerase Chain Reaction; Sequence Analysis, DNA; Stem Cells; Sulfites | 2015 |
Weakened N3 Hydrogen Bonding by 5-Formylcytosine and 5-Carboxylcytosine Reduces Their Base-Pairing Stability.
Topics: Base Pairing; Cytosine; DNA; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Nucleic Acid Denaturation; Spectroscopy, Fourier Transform Infrared; Thymine DNA Glycosylase | 2016 |
Tissue-Specific Differences in DNA Modifications (5-Hydroxymethylcytosine, 5-Formylcytosine, 5-Carboxylcytosine and 5-Hydroxymethyluracil) and Their Interrelationships.
Topics: 5-Methylcytosine; Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Cytosine; Dioxygenases; DNA; DNA Methylation; Epigenesis, Genetic; Gene Expression; Kidney; Liver; Lung; Male; Myocardium; Organ Specificity; Pentoxyl; Rats; Rats, Wistar; Swine; Tandem Mass Spectrometry; Thymus Gland | 2015 |
Effects of cytosine modifications on DNA flexibility and nucleosome mechanical stability.
Topics: 5-Methylcytosine; Biomechanical Phenomena; Cytosine; DNA; DNA Methylation; Molecular Dynamics Simulation; Nucleosomes; Oxidation-Reduction | 2016 |
Methylation-assisted bisulfite sequencing to simultaneously map 5fC and 5caC on a genome-wide scale for DNA demethylation analysis.
Topics: 5-Methylcytosine; Animals; Base Sequence; Cell Line; CpG Islands; Cytosine; DNA; DNA Methylation; Epigenesis, Genetic; Humans; Mice; Sequence Analysis, DNA; Sulfites | 2016 |
TET2-mediated 5-hydroxymethylcytosine induces genetic instability and mutagenesis.
Topics: 5-Methylcytosine; Animals; B-Lymphocytes; Base Sequence; Cell Line; Cytosine; Dioxygenases; DNA Repair; DNA-Binding Proteins; Epigenesis, Genetic; Fibroblasts; Genomic Instability; Humans; Hydroxylation; Megakaryocyte Progenitor Cells; Mice; Mutagenesis; Proto-Oncogene Proteins; S Phase; Thymine DNA Glycosylase; Tumor Suppressor Protein p53 | 2016 |
Isocitrate Dehydrogenase 2 Dysfunction Contributes to 5-hydroxymethylcytosine Depletion in Gastric Cancer Cells.
Topics: 5-Methylcytosine; Cytosine; DNA Methylation; Female; Humans; Isocitrate Dehydrogenase; Ketoglutaric Acids; Male; Stomach Neoplasms | 2016 |
Preferential 5-Methylcytosine Oxidation in the Linker Region of Reconstituted Positioned Nucleosomes by Tet1 Protein.
Topics: 5-Methylcytosine; Cytosine; DNA; DNA Methylation; Nucleosomes; Oxidation-Reduction | 2016 |
TET1-Mediated Oxidation of 5-Formylcytosine (5fC) to 5-Carboxycytosine (5caC) in RNA.
Topics: 5-Methylcytosine; Base Sequence; Biocatalysis; Catalytic Domain; Chromatography, High Pressure Liquid; Cytosine; Humans; Mixed Function Oxygenases; Oxidation-Reduction; Proto-Oncogene Proteins; Recombinant Proteins; RNA; Tandem Mass Spectrometry | 2017 |
Structural Basis for Excision of 5-Formylcytosine by Thymine DNA Glycosylase.
Topics: 5-Methylcytosine; Catalytic Domain; Crystallography, X-Ray; Cytosine; DNA; DNA Methylation; DNA Repair; Humans; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Oxidation-Reduction; Protein Binding; Protein Domains; Substrate Specificity; Thymine DNA Glycosylase | 2016 |
Vitamin C enhances substantially formation of 5-hydroxymethyluracil in cellular DNA.
Topics: 5-Methylcytosine; Ascorbic Acid; Cytosine; DNA; DNA Methylation; HCT116 Cells; Humans; Mixed Function Oxygenases; Oxidation-Reduction; Pentoxyl; Proto-Oncogene Proteins; Spectrometry, Mass, Electrospray Ionization; Thymine | 2016 |
Combinatorial DNA methylation codes at repetitive elements.
Topics: 5-Methylcytosine; Animals; Cell Differentiation; Cytosine; DNA Methylation; DNA Transposable Elements; Epigenesis, Genetic; Fibroblasts; Genome; Mice; Mouse Embryonic Stem Cells; Primary Cell Culture; Repetitive Sequences, Nucleic Acid; Thymine DNA Glycosylase | 2017 |
Differential expression of ten-eleven translocation genes in endometrial cancers.
Topics: 5-Methylcytosine; Aged; Cytosine; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Endometrial Neoplasms; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Humans; Kaplan-Meier Estimate; Middle Aged; Mixed Function Oxygenases; Prognosis; Proto-Oncogene Proteins | 2017 |
Nei-like 1 (NEIL1) excises 5-carboxylcytosine directly and stimulates TDG-mediated 5-formyl and 5-carboxylcytosine excision.
Topics: Cytosine; DNA; DNA Glycosylases; DNA Repair; Humans; Mutant Proteins; Protein Binding; Thymine DNA Glycosylase | 2017 |
Functional impacts of 5-hydroxymethylcytosine, 5-formylcytosine, and 5-carboxycytosine at a single hemi-modified CpG dinucleotide in a gene promoter.
Topics: 5-Methylcytosine; Animals; Base Sequence; CpG Islands; Cyclic AMP Response Element-Binding Protein; Cytosine; DNA; DNA Methylation; Gene Expression Regulation; Humans; Promoter Regions, Genetic; Protein Binding; Thymine DNA Glycosylase | 2017 |
Defining the impact of sumoylation on substrate binding and catalysis by thymine DNA glycosylase.
Topics: Catalysis; Cytosine; Fluorescence Polarization; Humans; Small Ubiquitin-Related Modifier Proteins; SUMO-1 Protein; Sumoylation; Thymine DNA Glycosylase | 2018 |
Two are better than one: HPoxBS - hairpin oxidative bisulfite sequencing.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferase 1; DNA Methylation; DNA-Binding Proteins; Embryonic Stem Cells; Gene Expression Regulation; High-Throughput Nucleotide Sequencing; Mice; Oxidation-Reduction; Proto-Oncogene Proteins; Sulfites | 2018 |
Dysregulation and prognostic potential of 5-methylcytosine (5mC), 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5-carboxylcytosine (5caC) levels in prostate cancer.
Topics: 5-Methylcytosine; Adult; Aged; Cytosine; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Male; Middle Aged; Prognosis; Prostatic Neoplasms; Receptors, Estrogen; Tissue Array Analysis | 2018 |
Genomic distribution of 5-formylcytosine and 5-carboxylcytosine in human preimplantation embryos.
Topics: Blastocyst; Chromosomes, Human; Cytosine; Genome, Human; Humans | 2018 |
Vitrification of murine mature metaphase II oocytes perturbs DNA methylation reprogramming during preimplantation embryo development.
Topics: 5-Methylcytosine; Animals; Blastocyst; Cryopreservation; Cytosine; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Embryonic Development; Female; Fertilization in Vitro; Metaphase; Mice; Morula; Oocytes; Oogenesis; Pregnancy; Proto-Oncogene Proteins; Vitrification | 2019 |
DNA repair enzymes ALKBH2, ALKBH3, and AlkB oxidize 5-methylcytosine to 5-hydroxymethylcytosine, 5-formylcytosine and 5-carboxylcytosine in vitro.
Topics: 5-Methylcytosine; AlkB Enzymes; AlkB Homolog 2, Alpha-Ketoglutarate-Dependent Dioxygenase; AlkB Homolog 3, Alpha-Ketoglutarate-Dependent Dioxygenase; Animals; Computational Biology; CpG Islands; Cytosine; DNA; DNA Methylation; Epigenesis, Genetic; Humans; Molecular Structure; Oxidation-Reduction | 2019 |
5-Methylcytosine is Oxidized to the Natural Metabolites of TET Enzymes by a Biomimetic Iron(IV)-Oxo Complex.
Topics: 5-Methylcytosine; Biomimetic Materials; Cerium; Coordination Complexes; Cytosine; Dioxygenases; Epigenesis, Genetic; Iron; Kinetics; Oxidation-Reduction; Thermodynamics | 2019 |
The clinical values of dysregulated DNA methylation and demethylation intermediates in acute lymphoblastic leukemia.
Topics: 5-Methylcytosine; Adolescent; Adult; Aged; Area Under Curve; Biomarkers, Tumor; Cell Lineage; Child; Cytosine; Demethylation; DNA Methylation; DNA, Neoplasm; Female; Humans; Male; Middle Aged; Oxidation-Reduction; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; ROC Curve; Young Adult | 2019 |
Mapping Retinoic Acid-Dependant 5mC Derivatives in Mouse Embryonic Fibroblasts.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA Methylation; Fibroblasts; Kruppel-Like Transcription Factors; Methyltransferases; Mice; Molecular Structure; Sequence Analysis, DNA; Tretinoin | 2019 |
Polymerization retardation isothermal amplification (PRIA): a strategy enables sensitively quantify genome-wide 5-methylcytosine oxides rapidly on handy instruments with nanoscale sample input.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA; DNA Methylation; DNA-Directed DNA Polymerase; Epigenomics; Genome; Humans; Mice; Oxides; Polymerase Chain Reaction; Polymerization; Rats | 2019 |
Ultrasensitive Determination of Rare Modified Cytosines Based on Novel Hydrazine Labeling Reagents.
Topics: Animals; Chromatography, High Pressure Liquid; Cytosine; DNA; Hydrazines; Hydrophobic and Hydrophilic Interactions; Indicators and Reagents; Limit of Detection; Mice; Molecular Structure; Tandem Mass Spectrometry; Triazines | 2019 |
Epigenetic modification of cytosines fine tunes the stability of i-motif DNA.
Topics: 5-Methylcytosine; Cell Line; Cytosine; DNA; DNA Methylation; Epigenesis, Genetic; Humans; Hydrogen-Ion Concentration; MCF-7 Cells; Nucleotide Motifs | 2020 |
Mass spectrometry reveals the presence of specific set of epigenetic DNA modifications in the Norway spruce genome.
Topics: 5-Methylcytosine; Chromatography, High Pressure Liquid; Cytosine; DNA Methylation; Epigenesis, Genetic; Genome, Plant; Mass Spectrometry; Norway; Picea | 2019 |
Quantification of DNA Modifications Using Two-Dimensional Ultraperformance Liquid Chromatography Tandem Mass Spectrometry (2D-UPLC-MS/MS).
Topics: 5-Methylcytosine; Animals; Chromatography, High Pressure Liquid; Cytosine; DNA; DNA Methylation; Epigenesis, Genetic; Epigenomics; Hydrolysis; Tandem Mass Spectrometry; Zebrafish | 2021 |
Immunochemical Detection of Modified Cytosine Species in Mammalian Preimplantation Embryos.
Topics: 5-Methylcytosine; Animals; Blastocyst; Cytosine; DNA Methylation; Embryo, Mammalian; Embryonic Development; Humans; Immunochemistry; Mammals; Microscopy, Confocal; Zygote | 2021 |
Detection of Low-Abundance DNA Modifications Using Signal Amplification-Based Immunocytochemistry.
Topics: 5-Methylcytosine; Animals; Antibodies; Cell Nucleus; Cytosine; DNA; DNA Methylation; Epigenesis, Genetic; Humans; Immunohistochemistry; Pentoxyl; Peroxidase | 2021 |
Immunohistochemical Detection of 5-Hydroxymethylcytosine and 5-Carboxylcytosine in Sections of Zebrafish Embryos.
Topics: 5-Methylcytosine; Animals; Antibodies; Cell Nucleus; Cytosine; Dioxygenases; DNA; DNA Methylation; Embryo, Nonmammalian; Immunohistochemistry; Zebrafish | 2021 |
Immunochemical Detection of Modified Species of Cytosine in Plant Tissues.
Topics: 5-Methylcytosine; Antibodies; Cell Nucleus; Cytosine; Dioxygenases; DNA; DNA Methylation; Epigenesis, Genetic; Fluorescent Dyes; Immunohistochemistry; Plants | 2021 |
Antigen Retrieval for Immunostaining of Modified Cytosine Species.
Topics: 5-Methylcytosine; Animals; Antibodies; Antigens; Cytosine; DNA; DNA Methylation; Epigenesis, Genetic; Fluorescent Antibody Technique; Humans | 2021 |
Analysis of 5-Carboxylcytosine Distribution Using DNA Immunoprecipitation.
Topics: 5-Methylcytosine; Animals; Chromatin Immunoprecipitation; Cytosine; DNA; DNA Methylation; Humans; Immunoprecipitation | 2021 |
bZIP Dimers CREB1, ATF2, Zta, ATF3|cJun, and cFos|cJun Prefer to Bind to Some Double-Stranded DNA Sequences Containing 5-Formylcytosine and 5-Carboxylcytosine.
Topics: 5-Methylcytosine; Amino Acid Sequence; Animals; Basic-Leucine Zipper Transcription Factors; Cytosine; DNA; Mice; Protein Array Analysis; Protein Binding | 2020 |
TET-TDG Active DNA Demethylation at CpG and Non-CpG Sites.
Topics: 5-Methylcytosine; CpG Islands; Cytosine; Dioxygenases; DNA Demethylation; DNA Repair; DNA-Binding Proteins; Epigenesis, Genetic; Humans; Oxidation-Reduction; Proto-Oncogene Proteins; Thymine DNA Glycosylase | 2021 |
Distinguishing Active Versus Passive DNA Demethylation Using Illumina MethylationEPIC BeadChip Microarrays.
Topics: 5-Methylcytosine; Computational Biology; Cytosine; DNA; DNA Demethylation; DNA Methylation; Epigenesis, Genetic; High-Throughput Nucleotide Sequencing; Humans; Microarray Analysis; Oxidation-Reduction; Sulfites | 2021 |
Roles of TET and TDG in DNA demethylation in proliferating and non-proliferating immune cells.
Topics: 5-Methylcytosine; Animals; Cell Differentiation; Cell Proliferation; Cytosine; Dioxygenases; DNA; DNA Methylation; DNA-Binding Proteins; Enhancer Elements, Genetic; Gene Expression; Genetic Loci; Hematopoiesis; Interleukin-4; Isoenzymes; Lipopolysaccharides; Longevity; Macrophages; Mice; Mice, Knockout; T-Lymphocytes; Thymine DNA Glycosylase | 2021 |
Proteome-Wide Profiling of Readers for DNA Modification.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA; DNA Methylation; Epigenesis, Genetic; Gene Expression Profiling; Humans; Mice; Mice, Inbred C57BL; Models, Animal; Proteome; Transcription Factors | 2021 |
Direct and Base Excision Repair-Mediated Regulation of a GC-Rich
Topics: CpG Islands; Cytosine; Deoxyribonuclease (Pyrimidine Dimer); DNA; DNA Damage; DNA Demethylation; DNA Methylation; DNA Repair; Epigenesis, Genetic; HeLa Cells; Humans; Promoter Regions, Genetic; Thymine DNA Glycosylase | 2021 |