Compounds > sodium salicylate
Page last updated: 2024-09-04

sodium salicylate and sulfasalazine

sodium salicylate has been researched along with sulfasalazine in 3 studies

Compound Research Comparison

Studies
(sodium salicylate)		Trials
(sodium salicylate)		Recent Studies (post-2010)
(sodium salicylate)		Studies
(sulfasalazine)		Trials
(sulfasalazine)		Recent Studies (post-2010) (sulfasalazine)
2,031501714,437585938

Protein Interaction Comparison

ProteinTaxonomysodium salicylate (IC50)sulfasalazine (IC50)
Multidrug resistance-associated protein 4Homo sapiens (human)1.5
Solute carrier organic anion transporter family member 2B1 Homo sapiens (human)3
Carbonic anhydrase 1Homo sapiens (human)3.04
Carbonic anhydrase 2Homo sapiens (human)4.49
Mitogen-activated protein kinase 1Homo sapiens (human)6.332
Sodium/bile acid cotransporterHomo sapiens (human)9.6
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)0.46
Cystine/glutamate transporterHomo sapiens (human)0.16
Solute carrier organic anion transporter family member 1B1Homo sapiens (human)0.56

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's1 (33.33)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cronstein, BN; Montesinos, MC; Weissmann, G1
Hatala, DA; Howell, SJ; Huang, K; Kern, TS; Zheng, L1
Bau, JT; Kurz, EU1

Other Studies

3 other study(ies) available for sodium salicylate and sulfasalazine

ArticleYear
Salicylates and sulfasalazine, but not glucocorticoids, inhibit leukocyte accumulation by an adenosine-dependent mechanism that is independent of inhibition of prostaglandin synthesis and p105 of NFkappaB.
    Proceedings of the National Academy of Sciences of the United States of America, 1999, May-25, Volume: 96, Issue:11

    Topics: Adenosine Deaminase; Animals; Aspirin; Carrageenan; Cyclooxygenase 1; Cyclooxygenase 2; Female; Glucocorticoids; Inflammation; Isoenzymes; Leukocytes; Male; Membrane Proteins; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Knockout; NF-kappa B; NF-kappa B p50 Subunit; Prostaglandin-Endoperoxide Synthases; Protein Precursors; Purinergic P1 Receptor Antagonists; Salicylates; Sodium Salicylate; Sulfasalazine; Theobromine

1999
Salicylate-based anti-inflammatory drugs inhibit the early lesion of diabetic retinopathy.
    Diabetes, 2007, Volume: 56, Issue:2

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Death; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Inflammation; Male; NF-kappa B; NF-kappa B p50 Subunit; Protein Transport; Random Allocation; Rats; Rats, Inbred Lew; Retina; Retinal Ganglion Cells; Salicylates; Sodium Salicylate; Sulfasalazine; Transcription Factor RelA

2007
Structural determinants of the catalytic inhibition of human topoisomerase IIα by salicylate analogs and salicylate-based drugs.
    Biochemical pharmacology, 2014, Jun-15, Volume: 89, Issue:4

    Topics: Adenosine Triphosphate; Antigens, Neoplasm; Antineoplastic Agents; Biocatalysis; Diflunisal; DNA Fragmentation; DNA Topoisomerases, Type II; DNA-Binding Proteins; DNA, Catenated; DNA, Kinetoplast; DNA, Neoplasm; DNA, Superhelical; Doxorubicin; Enzyme Inhibitors; Humans; Hydrolysis; MCF-7 Cells; Models, Molecular; Molecular Conformation; Neoplasm Proteins; Plasmids; Salicylates; Sodium Salicylate; Sulfasalazine

2014