Compounds > sodium salicylate
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sodium salicylate and diclofenac

sodium salicylate has been researched along with diclofenac in 9 studies

Compound Research Comparison

Studies
(sodium salicylate)		Trials
(sodium salicylate)		Recent Studies (post-2010)
(sodium salicylate)		Studies
(diclofenac)		Trials
(diclofenac)		Recent Studies (post-2010) (diclofenac)
2,031501718,8741,8743,616

Protein Interaction Comparison

ProteinTaxonomysodium salicylate (IC50)diclofenac (IC50)
Aldo-keto reductase family 1 member B10Homo sapiens (human)1.9
Prostaglandin G/H synthase 1 Bos taurus (cattle)0.003
Prostaglandin G/H synthase 1Ovis aries (sheep)1.3376
Interleukin-8Homo sapiens (human)0.008
Prostaglandin G/H synthase 1Homo sapiens (human)0.0415
Sodium- and chloride-dependent GABA transporter 1Rattus norvegicus (Norway rat)0.5
C-X-C chemokine receptor type 1Homo sapiens (human)0.012
Sodium- and chloride-dependent GABA transporter 2Rattus norvegicus (Norway rat)0.5
Sodium- and chloride-dependent GABA transporter 3Rattus norvegicus (Norway rat)0.5
Prostaglandin G/H synthase 2Homo sapiens (human)0.4165
Prostaglandin G/H synthase 2 Rattus norvegicus (Norway rat)0.5
Sodium- and chloride-dependent betaine transporterRattus norvegicus (Norway rat)0.5
Prostaglandin G/H synthase 2Ovis aries (sheep)1.6867
Prostaglandin G/H synthase 2Mus musculus (house mouse)0.0502
Solute carrier family 22 member 6Homo sapiens (human)4
Prostaglandin G/H synthase 1 Rattus norvegicus (Norway rat)0.5
P2Y purinoceptor 12Rattus norvegicus (Norway rat)0.02

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19901 (11.11)18.7374
1990's1 (11.11)18.2507
2000's6 (66.67)29.6817
2010's1 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kozubík, A; Netíková, J; Pipalová, I; Pospísil, M1
Demirtaş, RN; Oner, C1
Gülay, Z; Oktem, IM; Yücesoy, M1
Giuliano, F; Mitchell, JA; Warner, TD1
Banerjee, R; Mohanakumar, KP; Sairam, K; Saravanan, KS1
Brooks, G; Crabbe, MJ; Harper, JV; Shattock, MJ; Wang, Y; Yu, XM1
Bishop-Bailey, D; Mitchell, JA; Vojnovic, I; Warner, TD1
Deveci, MS; Dogrul, A; Gul, H; Gülmez, SE; Ossipov, MH; Porreca, F; Tulunay, FC1
Kazama, I; Maruyama, Y; Murata, Y1

Trials

1 trial(s) available for sodium salicylate and diclofenac

ArticleYear
The treatment of lateral epicondylitis by iontophoresis of sodium salicylate and sodium diclofenac.
    Clinical rehabilitation, 1998, Volume: 12, Issue:1

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Female; Humans; Iontophoresis; Male; Middle Aged; Pain Measurement; Random Allocation; Sodium Salicylate; Tennis Elbow

1998

Other Studies

8 other study(ies) available for sodium salicylate and diclofenac

ArticleYear
Effect of indomethacin, diclofenac sodium and sodium salicylate on peripheral blood cell counts in sublethally gamma-irradiated mice.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 1989, Volume: 165, Issue:8

    Topics: Animals; Blood Cell Count; Diclofenac; Dose-Response Relationship, Drug; Hematopoiesis; Indomethacin; Male; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Radiation Injuries, Experimental; Sodium Salicylate; Time Factors

1989
In-vitro synergistic effect of fluconazole with nonsteroidal anti-inflammatory agents against Candida albicans strains.
    Journal of chemotherapy (Florence, Italy), 2000, Volume: 12, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antifungal Agents; Candida albicans; Diclofenac; Drug Synergism; Fluconazole; Humans; Microbial Sensitivity Tests; Piroxicam; Sodium Salicylate

2000
Sodium salicylate inhibits prostaglandin formation without affecting the induction of cyclooxygenase-2 by bacterial lipopolysaccharide in vivo.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 299, Issue:3

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blotting, Western; Cardiovascular System; Cholinesterase Inhibitors; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Drug Interactions; Enzyme Induction; Isoenzymes; Isoflurophate; Lipopolysaccharides; Male; Nitrates; Nitrites; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Rats, Wistar; Sodium Salicylate

2001
Non-steroidal anti-inflammatory drug sodium salicylate, but not diclofenac or celecoxib, protects against 1-methyl-4-phenyl pyridinium-induced dopaminergic neurotoxicity in rats.
    Brain research, 2003, Mar-21, Volume: 966, Issue:2

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Corpus Striatum; Diclofenac; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Gentisates; Hydroxybenzoates; Hydroxyl Radical; In Vitro Techniques; Male; Mortality; Neurodegenerative Diseases; Neuroprotective Agents; Pyrazoles; Rats; Rats, Inbred Strains; Rats, Sprague-Dawley; Sodium Salicylate; Sulfonamides

2003
Non-steroidal anti-inflammatory drugs (NSAIDs) inhibit vascular smooth muscle cell proliferation via differential effects on the cell cycle.
    The Journal of pharmacy and pharmacology, 2003, Volume: 55, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta; Aspirin; Cell Division; Cell Line; Diclofenac; Dose-Response Relationship, Drug; Flow Cytometry; Ibuprofen; Indomethacin; Muscle, Smooth, Vascular; Rats; Sodium Salicylate; Sulindac

2003
Influence of plasma protein on the potencies of inhibitors of cyclooxygenase-1 and -2.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2006, Volume: 20, Issue:3

    Topics: Aspirin; Blood Platelets; Blood Proteins; Calcimycin; Calcium; Celecoxib; Cell Line; Cerebrospinal Fluid Proteins; Cyclooxygenase 1; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Humans; Indomethacin; Ionophores; Lactones; Meloxicam; Naproxen; Organ Specificity; Organic Chemicals; Protein Binding; Pyrazoles; Sodium Salicylate; Sulfonamides; Sulfones; Synovial Fluid; Thiazines; Thiazoles; Thromboxane A2

2006
The local antinociceptive actions of nonsteroidal antiinflammatory drugs in the mouse radiant heat tail-flick test.
    Anesthesia and analgesia, 2007, Volume: 104, Issue:4

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diclofenac; Dipyrone; Disease Models, Animal; Dose-Response Relationship, Drug; Hot Temperature; Injections, Intradermal; Injections, Intraperitoneal; Ketorolac; Lysine; Male; Mice; Mice, Inbred BALB C; Motor Activity; Naloxone; Narcotic Antagonists; Pain; Reaction Time; Sodium Salicylate; Tail; Time Factors

2007
Suppressive effects of nonsteroidal anti-inflammatory drugs diclofenac sodium, salicylate and indomethacin on delayed rectifier K+-channel currents in murine thymocytes.
    Immunopharmacology and immunotoxicology, 2012, Volume: 34, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Indomethacin; Kv1.3 Potassium Channel; Male; Membrane Potentials; Mice; Sodium Salicylate; Thymocytes

2012