Protein | Taxonomy | sodium salicylate (IC50) | chlorpromazine (IC50) |
Adenylate cyclase type 1 | Rattus norvegicus (Norway rat) | | 1.3 |
Spike glycoprotein | Betacoronavirus England 1 | | 9.51 |
Replicase polyprotein 1ab | Betacoronavirus England 1 | | 9.51 |
Solute carrier family 22 member 1 | Homo sapiens (human) | | 4.3 |
Transmembrane protease serine 2 | Homo sapiens (human) | | 9.51 |
Glutamate receptor ionotropic, NMDA 2D | Homo sapiens (human) | | 0.85 |
Glutamate receptor ionotropic, NMDA 3B | Homo sapiens (human) | | 0.85 |
Voltage-dependent L-type calcium channel subunit alpha-1F | Homo sapiens (human) | | 3.4 |
5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | | 0.0052 |
Potassium channel subfamily K member 2 | Homo sapiens (human) | | 2.7 |
Tyrosine-protein kinase Fyn | Homo sapiens (human) | | 8.68 |
Procathepsin L | Homo sapiens (human) | | 9.51 |
Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | | 0.019 |
Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | | 0.652 |
Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | | 0.149 |
Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | | 0.025 |
Alpha-2A adrenergic receptor | Homo sapiens (human) | | 0.352 |
Replicase polyprotein 1a | Severe acute respiratory syndrome-related coronavirus | | 9.51 |
Replicase polyprotein 1ab | Human coronavirus 229E | | 9.51 |
Replicase polyprotein 1ab | Severe acute respiratory syndrome-related coronavirus | | 9.51 |
Calmodulin-1 | Homo sapiens (human) | | 7.63 |
Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | | 9.51 |
Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | | 0.083 |
Angiotensin-converting enzyme | Oryctolagus cuniculus (rabbit) | | 5.8275 |
D(2) dopamine receptor | Homo sapiens (human) | | 0.0142 |
Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | | 0.031 |
Alpha-2B adrenergic receptor | Homo sapiens (human) | | 0.026 |
Alpha-2C adrenergic receptor | Homo sapiens (human) | | 0.374 |
D | Rattus norvegicus (Norway rat) | | 0.1414 |
D(3) dopamine receptor | Rattus norvegicus (Norway rat) | | 0.0416 |
5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | | 4.685 |
Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | | 1.4791 |
D(2) dopamine receptor | Bos taurus (cattle) | | 0.5328 |
Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | | 0.206 |
D(1A) dopamine receptor | Homo sapiens (human) | | 0.225 |
D(4) dopamine receptor | Homo sapiens (human) | | 1.365 |
Adenylate cyclase type 3 | Rattus norvegicus (Norway rat) | | 1.3 |
Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | | 1.4791 |
Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | | 1.4791 |
Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | | 0.031 |
Sodium-dependent noradrenaline transporter | Homo sapiens (human) | | 0.019 |
Sodium-dependent dopamine transporter | Rattus norvegicus (Norway rat) | | 1.4791 |
Histamine H2 receptor | Homo sapiens (human) | | 2.626 |
Alpha-1D adrenergic receptor | Homo sapiens (human) | | 0.004 |
D(1B) dopamine receptor | Rattus norvegicus (Norway rat) | | 0.0416 |
Adenylate cyclase type 2 | Rattus norvegicus (Norway rat) | | 1.3 |
Adenylate cyclase type 4 | Rattus norvegicus (Norway rat) | | 1.3 |
5-hydroxytryptamine receptor 2A | Homo sapiens (human) | | 0.0036 |
5-hydroxytryptamine receptor 2C | Homo sapiens (human) | | 0.0052 |
5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | | 4.685 |
Trypanothione reductase | Trypanosoma cruzi | | 5.8 |
D(4) dopamine receptor | Rattus norvegicus (Norway rat) | | 0.0416 |
Sodium-dependent serotonin transporter | Homo sapiens (human) | | 0.0795 |
Melanocortin receptor 5 | Homo sapiens (human) | | 7.617 |
Pleiotropic ABC efflux transporter of multiple drugs | Saccharomyces cerevisiae S288C | | 4.5 |
Histamine H1 receptor | Homo sapiens (human) | | 0.0145 |
Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | | 1.3 |
D(3) dopamine receptor | Homo sapiens (human) | | 0.012 |
Sodium channel protein type 1 subunit alpha | Homo sapiens (human) | | 4.3 |
Sodium channel protein type 4 subunit alpha | Homo sapiens (human) | | 4.3 |
Adenylate cyclase type 8 | Rattus norvegicus (Norway rat) | | 1.3 |
5-hydroxytryptamine receptor 2B | Homo sapiens (human) | | 0.126 |
Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | | 0.031 |
5-hydroxytryptamine receptor 6 | Homo sapiens (human) | | 0.057 |
Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | | 9.51 |
D(2) dopamine receptor | Rattus norvegicus (Norway rat) | | 0.0365 |
Calmodulin | Bos taurus (cattle) | | 2.5 |
Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | | 1.3 |
Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | | 1.3 |
Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | | 1.3 |
Sodium channel protein type 7 subunit alpha | Homo sapiens (human) | | 4.3 |
Voltage-dependent L-type calcium channel subunit alpha-1D | Homo sapiens (human) | | 3.4 |
Sodium-dependent dopamine transporter | Homo sapiens (human) | | 2.643 |
Adenylate cyclase type 6 | Rattus norvegicus (Norway rat) | | 1.3 |
Adenylate cyclase type 5 | Rattus norvegicus (Norway rat) | | 1.3 |
Glutamate receptor ionotropic, NMDA 1 | Homo sapiens (human) | | 0.85 |
Aldehyde oxidase | Homo sapiens (human) | | 0.57 |
Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | | 1.9602 |
Glutamate receptor ionotropic, NMDA 2A | Homo sapiens (human) | | 0.85 |
Glutamate receptor ionotropic, NMDA 2B | Homo sapiens (human) | | 0.85 |
Voltage-dependent L-type calcium channel subunit alpha-1S | Homo sapiens (human) | | 3.4 |
Voltage-dependent L-type calcium channel subunit alpha-1C | Homo sapiens (human) | | 3.4 |
Sodium channel protein type 5 subunit alpha | Homo sapiens (human) | | 4.3 |
Glutamate receptor ionotropic, NMDA 2C | Homo sapiens (human) | | 0.85 |
Sodium channel protein type 9 subunit alpha | Homo sapiens (human) | | 4.3 |
Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | | 1.3 |
Nuclear receptor subfamily 3 group C member 3 | Bos taurus (cattle) | | 5.8275 |
Adenylyl cyclase 7 | Rattus norvegicus (Norway rat) | | 1.3 |
Glutamate receptor ionotropic, NMDA 3A | Homo sapiens (human) | | 0.85 |
Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | | 1.3 |
D | Bos taurus (cattle) | | 0.646 |
Sodium channel protein type 2 subunit alpha | Homo sapiens (human) | | 4.3 |
Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | | 0.451 |
Angiotensin-converting enzyme 2 | Homo sapiens (human) | | 9.51 |
Sodium channel protein type 3 subunit alpha | Homo sapiens (human) | | 4.3 |
Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | | 1.3 |
Sodium channel protein type 11 subunit alpha | Homo sapiens (human) | | 4.3 |
Sodium channel protein type 8 subunit alpha | Homo sapiens (human) | | 4.3 |
Sodium channel protein type 10 subunit alpha | Homo sapiens (human) | | 4.3 |
Authors | Studies |
Bozkowa, K; Hofman, H; Piekarczyk, A; Prokopczyk, J; Wańkowicz, B | 1 |
Meiselman, HJ | 1 |
Chabanel, A; Chien, S; Reinhart, W | 1 |
Levy, L | 1 |
Selye, H; Somogyi, A | 1 |
Collier, HO; McDonald-Gibson, WJ; Saeed, SA | 1 |
Frings, CS; Queen, CA | 1 |
Bhalla, TN; Bhargava, KP; Kohli, RP; Sinha, JN | 1 |
Buczko, W; Danysz, A; Moniuszko, J; Wiśniewski, K; Zarebski, M | 1 |
Betticher, DC; Geiser, J; Reinhart, WH | 1 |
SHARP, GW | 1 |
CHITTAL, SM; SHETH, UK | 1 |
GOLDMAN, AS; YAKOVAC, WC | 1 |
KOLODNY, SC; LASKIN, DM | 1 |
BIZZI, A; CODEGONI, AM; GARATTINI, S | 1 |
KIRPEKAR, SM; LEWIS, JJ | 1 |
Oghalai, JS | 1 |
Kazama, I; Kokumai, T; Maruyama, Y; Takahashi, S | 1 |
Article | Year |
[Binding capacity of some drugs to plasma proteins of newborns in comparison with adults (author's transl)].Klinische Padiatrie, 1977, Volume: 189, Issue:5
Topics: Adult; Age Factors; Animals; Chlorpromazine; Fetal Blood; Humans; Infant; Infant, Newborn; Protein Binding; Rabbits; Sodium Salicylate; Sulfamethazine; Sulfamethoxazole; Sulfonamides | 1977 |
Rheology of shape-transformed human red cells.Biorheology, 1978, Volume: 15, Issue:3-4
Topics: Adult; Blood Viscosity; Chlorpromazine; Erythrocytes; Humans; Microscopy, Electron, Scanning; Nitrophenols; Rheology; Sodium Salicylate | 1978 |
Increased resistance to membrane deformation of shape-transformed human red blood cells.Blood, 1987, Volume: 69, Issue:3
Topics: Adenosine Triphosphate; Chlorpromazine; Erythrocyte Deformability; Erythrocyte Membrane; Erythrocytes, Abnormal; Humans; Membrane Fluidity; Sodium Salicylate; Stress, Mechanical | 1987 |
Effects of different classes of drugs on the passive cutaneous anaphylaxis.Archives internationales de pharmacodynamie et de therapie, 1967, Volume: 165, Issue:1
Topics: Animals; Anti-Inflammatory Agents; Chlorpromazine; Guinea Pigs; Iproniazid; Male; Mice; Passive Cutaneous Anaphylaxis; Phenylbutazone; Polymyxins; Prochlorperazine; Promazine; Rats; Reserpine; Sodium Salicylate; Thyroxine | 1967 |
Tourniquet poditis--an experimental pedal inflammation in the rat.Arzneimittel-Forschung, 1969, Volume: 19, Issue:6
Topics: Animals; Anti-Bacterial Agents; Chlorpromazine; Cyproheptadine; Depression, Chemical; Dextrans; Dibenzylchlorethamine; Edema; Female; Foot Diseases; Formaldehyde; Histamine; Hydrocortisone; Inflammation; Ischemia; Lead; p-Methoxy-N-methylphenethylamine; Phenoxybenzamine; Phentolamine; Polymyxins; Rats; Scandium; Serotonin; Sodium Salicylate; Stimulation, Chemical; Sympatholytics; Tourniquets | 1969 |
Apomorphine and morphine stimulate prostaglandin biosynthesis.Nature, 1974, Nov-01, Volume: 252, Issue:5478
Topics: Animals; Apomorphine; Aspirin; Cattle; Chlorpromazine; Chromatography, Thin Layer; Dose-Response Relationship, Drug; Male; Mixed Function Oxygenases; Morphine; Prostaglandins; Seminal Vesicles; Sodium Salicylate; Stimulation, Chemical; Tritium | 1974 |
Preparation and use of a urine control for certain drugs of abuse.Clinical chemistry, 1972, Volume: 18, Issue:11
Topics: Chlorpromazine; Chromatography, Thin Layer; Ethchlorvynol; Humans; Pharmaceutical Preparations; Sodium Salicylate; Substance-Related Disorders | 1972 |
Aconitine-induced writhing: a method for assessment of analgesic activity.Japanese journal of pharmacology, 1969, Volume: 19, Issue:1
Topics: Aconitum; Analgesics; Animals; Aspirin; Behavior, Animal; Chlorpromazine; Imipramine; Mephenesin; Methaqualone; Methods; Mice; Morphine; Phenoxybenzamine; Phenylbutazone; Phenytoin; Sodium Salicylate | 1969 |
[Effect of certain drugs in alloxan diabetes].Polski tygodnik lekarski (Warsaw, Poland : 1960), 1968, Mar-18, Volume: 23, Issue:12
Topics: Animals; Chlorpromazine; Diabetes Mellitus, Experimental; Epinephrine; Mice; Neostigmine; Sodium Salicylate | 1968 |
Effect of RBC shape and deformability on pulmonary O2 diffusing capacity and resistance to flow in rabbit lungs.Journal of applied physiology (Bethesda, Md. : 1985), 1995, Volume: 78, Issue:3
Topics: Animals; Blood Pressure; Chlorpromazine; Erythrocyte Deformability; Erythrocytes; In Vitro Techniques; Oxygen; Pulmonary Circulation; Pulmonary Diffusing Capacity; Rabbits; Sodium Salicylate; Vascular Resistance | 1995 |
Effect of certain anti-arthritic compounds on the permeability of synovial membrane in the rabbit.Annals of the rheumatic diseases, 1963, Volume: 22Topics: Animals; Chlorpromazine; Gold; Permeability; Phenylbutazone; Rabbits; Sodium Salicylate; Synovial Membrane | 1963 |
EFFECT OF DRUGS ON CONDITIONED AVOIDANCE RESPONSE IN RATS.Archives internationales de pharmacodynamie et de therapie, 1963, Aug-02, Volume: 144Topics: Avoidance Learning; Chlordiazepoxide; Chlorpromazine; Cocaine; Codeine; Conditioning, Operant; Ethanol; Hydroxyzine; Meperidine; Methylphenidate; Morphine; Pharmacology; Promethazine; Rats; Research; Sodium Salicylate | 1963 |
PREVENTION OF SALICYLATE TERATOGENICITY IN IMMOBILIZED RATS BY CERTAIN CENTRAL NERVOUS SYSTEM DEPRESSANTS.Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1964, Volume: 115Topics: Abnormalities, Drug-Induced; Central Nervous System Depressants; Chlorpromazine; Fetal Death; Immobilization; Pentobarbital; Pharmacology; Pregnancy; Pregnancy, Animal; Rats; Research; Salicylates; Sodium Salicylate; Toxicology | 1964 |
INHIBITION OF EXUDATE PRODUCTION BY ANTI-INFLAMMATORY DRUGS.Journal of oral therapeutics and pharmacology, 1965, Volume: 1Topics: Anti-Inflammatory Agents; Chlorpheniramine; Chlorpromazine; Deoxyribonuclease I; Exudates and Transudates; Hyaluronoglucosaminidase; Hydrocortisone; Inflammation; Pharmacology; Prednisolone; Promethazine; Rats; Research; Sodium Salicylate; Streptodornase and Streptokinase; Streptokinase; Trimeprazine; Trypsin | 1965 |
SALICYLATE, A POWERFUL INHIBITOR OF FREE FATTY ACID RELEASE.Nature, 1964, Dec-19, Volume: 204Topics: Adipose Tissue; Adrenalectomy; Adrenocorticotropic Hormone; Antimetabolites; Aspirin; Benzoates; Chlorpromazine; Cold Temperature; Fasting; Fatty Acids; Fatty Acids, Nonesterified; Lipid Metabolism; Norepinephrine; Pharmacology; Propylthiouracil; Rats; Research; Salicylates; Sodium Salicylate | 1964 |
Effects of reserpine, chlorpromazine and sodium salicylate on the enzymic activity of rat liver.British journal of pharmacology and chemotherapy, 1960, Volume: 15Topics: 2,4-Dinitrophenol; Animals; Chlorpromazine; Enzymes; Liver; Rats; Reserpine; Sodium Salicylate | 1960 |
Chlorpromazine inhibits cochlear function in guinea pigs.Hearing research, 2004, Volume: 198, Issue:1-2
Topics: Acoustic Stimulation; Action Potentials; Animals; Chlorpromazine; Cochlea; Cyclooxygenase Inhibitors; Dopamine Antagonists; Dose-Response Relationship, Drug; Endolymph; Female; Guinea Pigs; Hair Cells, Auditory, Outer; Male; Otoacoustic Emissions, Spontaneous; Perilymph; Sodium Salicylate; Spiral Ganglion; Stria Vascularis | 2004 |
Amphipaths differentially modulate membrane surface deformation in rat peritoneal mast cells during exocytosis.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2013, Volume: 31, Issue:4-5
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Membrane; Cells, Cultured; Chlorpromazine; Exocytosis; Fluorescent Dyes; Guanosine 5'-O-(3-Thiotriphosphate); Isoquinolines; Male; Mast Cells; Membrane Potentials; Microscopy, Confocal; Patch-Clamp Techniques; Peritoneal Cavity; Rats; Rats, Wistar; Sodium Salicylate | 2013 |