sodium-oxybate and nooglutil

sodium-oxybate has been researched along with nooglutil* in 1 studies

Other Studies

1 other study(ies) available for sodium-oxybate and nooglutil

Article	Year
[The sodium oxybutyrate and nooglutil correction of dopamine release in the striatum of prenatally alcoholized rat pups]. Biulleten' eksperimental'noi biologii i meditsiny, 1993, Volume: 116, Issue:7 The influence of prenatal exposure to ethanol on endogenous Dopamine (DA) release from perfused isolated striata of 20-day-old rats was studied, as well as its correction by nootropic drugs: sodium hydroxy butyrate and nooglutil. Administration of 20% ethanol per os at a daily dose of 5 mg per kg during the entire period of pregnancy led to a significant decrease in basal and K(+)-evoked DA efflux. Hydroxy-butyrate and Nooglutil (50 and 25 mg per kg, subcutaneously, daily from the 8th to the 20th day of life) normalized these alterations in alcohol-exposed neonates, although their effects on the offsprings of non-alcoholized rats were opposite. The probable neurochemical targets of ethanol and nootropics are discussed. Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Ethanol; Female; Glutamates; Male; Nicotinic Acids; Pregnancy; Prenatal Exposure Delayed Effects; Psychotropic Drugs; Rats; Sodium Oxybate	1993

Article

Year

[The sodium oxybutyrate and nooglutil correction of dopamine release in the striatum of prenatally alcoholized rat pups].

Biulleten' eksperimental'noi biologii i meditsiny, 1993, Volume: 116, Issue:7

The influence of prenatal exposure to ethanol on endogenous Dopamine (DA) release from perfused isolated striata of 20-day-old rats was studied, as well as its correction by nootropic drugs: sodium hydroxy butyrate and nooglutil. Administration of 20% ethanol per os at a daily dose of 5 mg per kg during the entire period of pregnancy led to a significant decrease in basal and K(+)-evoked DA efflux. Hydroxy-butyrate and Nooglutil (50 and 25 mg per kg, subcutaneously, daily from the 8th to the 20th day of life) normalized these alterations in alcohol-exposed neonates, although their effects on the offsprings of non-alcoholized rats were opposite. The probable neurochemical targets of ethanol and nootropics are discussed.

Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Ethanol; Female; Glutamates; Male; Nicotinic Acids; Pregnancy; Prenatal Exposure Delayed Effects; Psychotropic Drugs; Rats; Sodium Oxybate

1993