sodium-nitrite and indole-3-carboxylic-acid

sodium-nitrite has been researched along with indole-3-carboxylic-acid* in 1 studies

Other Studies

1 other study(ies) available for sodium-nitrite and indole-3-carboxylic-acid

Article	Year
Isolation and characterization of products from the nitrosation of the alkaloid gramine. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1985, Volume: 23, Issue:9 The nitrosation of gramine, a tertiary amine alkaloid present in barley malt, was carried out by reaction with sodium nitrite in buffered acetic acid (pH 3.4) for 1 hr at room temperature. Two major non-volatile products of the nitrosation reaction were isolated by preparative HPLC and characterized as indole-3-carboxylic acid and N1-nitroso-3-nitromethylindole. This interpretation was supported by spectral data. The nature of these products indicated that gramine did not undergo nitrosation by the expected mechanism of nitrosative dealkylation. A mechanism is offered to explain the labile nature of the dimethylamino group found in gramine. Topics: Alkaloids; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Indole Alkaloids; Indoles; Isomerism; Nitrites; Sodium Nitrite	1985

Article

Year

Isolation and characterization of products from the nitrosation of the alkaloid gramine.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1985, Volume: 23, Issue:9

The nitrosation of gramine, a tertiary amine alkaloid present in barley malt, was carried out by reaction with sodium nitrite in buffered acetic acid (pH 3.4) for 1 hr at room temperature. Two major non-volatile products of the nitrosation reaction were isolated by preparative HPLC and characterized as indole-3-carboxylic acid and N1-nitroso-3-nitromethylindole. This interpretation was supported by spectral data. The nature of these products indicated that gramine did not undergo nitrosation by the expected mechanism of nitrosative dealkylation. A mechanism is offered to explain the labile nature of the dimethylamino group found in gramine.

Topics: Alkaloids; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Indole Alkaloids; Indoles; Isomerism; Nitrites; Sodium Nitrite

1985