sodium-nitrite and gramine

sodium-nitrite has been researched along with gramine* in 2 studies

Other Studies

2 other study(ies) available for sodium-nitrite and gramine

Article	Year
Identification of minor nitrosation products of the alkaloid gramine by mass spectrometry. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1987, Volume: 25, Issue:11 The nitrosation of gramine, a tertiary amine alkaloid present in barley malt, was carried out by reaction with sodium nitrite in buffered acetic acid (pH 3.4) for 1 hr at room temperature. Following the previous isolation and identification of the major nitrosation products (Ahmad et al. Fd Chem. Toxic. 1985, 23, 841), two minor products were isolated by HPLC and identified as indolin-3-one oxime and indole-3-aldehyde. Identification was based on mass spectrometry. The results give strong support to the hypothesis that gramine does not undergo nitrosation by nitrosative dealkylation. Topics: Alkaloids; Indole Alkaloids; Mass Spectrometry; Nitrosamines; Sodium Nitrite	1987
Isolation and characterization of products from the nitrosation of the alkaloid gramine. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1985, Volume: 23, Issue:9 The nitrosation of gramine, a tertiary amine alkaloid present in barley malt, was carried out by reaction with sodium nitrite in buffered acetic acid (pH 3.4) for 1 hr at room temperature. Two major non-volatile products of the nitrosation reaction were isolated by preparative HPLC and characterized as indole-3-carboxylic acid and N1-nitroso-3-nitromethylindole. This interpretation was supported by spectral data. The nature of these products indicated that gramine did not undergo nitrosation by the expected mechanism of nitrosative dealkylation. A mechanism is offered to explain the labile nature of the dimethylamino group found in gramine. Topics: Alkaloids; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Indole Alkaloids; Indoles; Isomerism; Nitrites; Sodium Nitrite	1985

Article

Year

Identification of minor nitrosation products of the alkaloid gramine by mass spectrometry.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1987, Volume: 25, Issue:11

The nitrosation of gramine, a tertiary amine alkaloid present in barley malt, was carried out by reaction with sodium nitrite in buffered acetic acid (pH 3.4) for 1 hr at room temperature. Following the previous isolation and identification of the major nitrosation products (Ahmad et al. Fd Chem. Toxic. 1985, 23, 841), two minor products were isolated by HPLC and identified as indolin-3-one oxime and indole-3-aldehyde. Identification was based on mass spectrometry. The results give strong support to the hypothesis that gramine does not undergo nitrosation by nitrosative dealkylation.

Topics: Alkaloids; Indole Alkaloids; Mass Spectrometry; Nitrosamines; Sodium Nitrite

1987

Isolation and characterization of products from the nitrosation of the alkaloid gramine.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1985, Volume: 23, Issue:9

The nitrosation of gramine, a tertiary amine alkaloid present in barley malt, was carried out by reaction with sodium nitrite in buffered acetic acid (pH 3.4) for 1 hr at room temperature. Two major non-volatile products of the nitrosation reaction were isolated by preparative HPLC and characterized as indole-3-carboxylic acid and N1-nitroso-3-nitromethylindole. This interpretation was supported by spectral data. The nature of these products indicated that gramine did not undergo nitrosation by the expected mechanism of nitrosative dealkylation. A mechanism is offered to explain the labile nature of the dimethylamino group found in gramine.

Topics: Alkaloids; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Indole Alkaloids; Indoles; Isomerism; Nitrites; Sodium Nitrite

1985