sodium-cyanoborohydride and titanium-tetrachloride

sodium-cyanoborohydride has been researched along with titanium-tetrachloride* in 1 studies

Other Studies

1 other study(ies) available for sodium-cyanoborohydride and titanium-tetrachloride

Article	Year
A convenient method for the stereoselective conversion of aryl peptidyl ketones into the corresponding aryl aminomethin derivatives, a novel class of modified peptides. Protein and peptide letters, 2005, Volume: 12, Issue:4 In this paper we describe a reductive amination procedure that can be employed in the preparation of a novel class of pseudopeptides in which a specific amide bond is replaced by a CH(Ar)NH group. The developed methodology, performed using NaBH(3)CN and TiCl(4), is characterized by the formation of diastereomeric intermediates in a relative 1:1 ratio. It provides aryl aminomethin pseudopeptides in moderate but satisfactory yields and with definite stereochemistry on the asymmetric centres next to the modified peptide bond. Topics: Amination; Benzylamines; Borohydrides; Dipeptides; Indicators and Reagents; Ketones; Molecular Conformation; Peptides; Titanium	2005

Article

Year

A convenient method for the stereoselective conversion of aryl peptidyl ketones into the corresponding aryl aminomethin derivatives, a novel class of modified peptides.

Protein and peptide letters, 2005, Volume: 12, Issue:4

In this paper we describe a reductive amination procedure that can be employed in the preparation of a novel class of pseudopeptides in which a specific amide bond is replaced by a CH(Ar)NH group. The developed methodology, performed using NaBH(3)CN and TiCl(4), is characterized by the formation of diastereomeric intermediates in a relative 1:1 ratio. It provides aryl aminomethin pseudopeptides in moderate but satisfactory yields and with definite stereochemistry on the asymmetric centres next to the modified peptide bond.

Topics: Amination; Benzylamines; Borohydrides; Dipeptides; Indicators and Reagents; Ketones; Molecular Conformation; Peptides; Titanium

2005