sodium-cyanoborohydride has been researched along with pipecolic-acid* in 1 studies
1 other study(ies) available for sodium-cyanoborohydride and pipecolic-acid
Article | Year |
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A one-pot, reductive amination/6-endo-trig cyclisation for the stereoselective synthesis of 6-substituted-4-oxopipecolic acids.
The first stereoselective synthesis of 2,6-trans-6-substituted-4-oxo-L-pipecolic acids using a tandem reductive amination/6-endo-trig cyclisation process is described. The sequential reduction and cyclisation mediated by sodium cyanoborohydride allowed the preparation of a series of highly functionalised 6-alkyl and 6-aryl analogues. Topics: Amination; Borohydrides; Crystallography, X-Ray; Cyclization; Molecular Conformation; Oxidation-Reduction; Pipecolic Acids; Stereoisomerism | 2011 |