Page last updated: 2024-09-03

sn 23862 and n-((n,n-dimethylamino)ethyl)-5-(n,n-bis(2-chloroethyl)amino)-2,4-dinitrobenzamide

sn 23862 has been researched along with n-((n,n-dimethylamino)ethyl)-5-(n,n-bis(2-chloroethyl)amino)-2,4-dinitrobenzamide in 5 studies

Compound Research Comparison

Studies
(sn 23862)
Trials
(sn 23862)
Recent Studies (post-2010)
(sn 23862)
Studies
(n-((n,n-dimethylamino)ethyl)-5-(n,n-bis(2-chloroethyl)amino)-2,4-dinitrobenzamide)
Trials
(n-((n,n-dimethylamino)ethyl)-5-(n,n-bis(2-chloroethyl)amino)-2,4-dinitrobenzamide)
Recent Studies (post-2010) (n-((n,n-dimethylamino)ethyl)-5-(n,n-bis(2-chloroethyl)amino)-2,4-dinitrobenzamide)
2004500

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (80.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cliffe, S; Denny, WA; Palmer, BD; Wilson, WR1
Atwell, GJ; Denny, WA; Palmer, BD; Schultz, D; Wilson, WR; Xu, XZ1
Anderson, RF; Boyd, M; Denny, WA; Palmer, BD; Wilson, WR1
Denny, WA; Lee, HH; Palmer, BD; Wilson, WR1
Atwell, GJ; Denny, WA; Hogg, A; Patterson, AV; Pruijn, FB; Pullen, SM; Wilson, WR; Yang, S1

Other Studies

5 other study(ies) available for sn 23862 and n-((n,n-dimethylamino)ethyl)-5-(n,n-bis(2-chloroethyl)amino)-2,4-dinitrobenzamide

ArticleYear
Hypoxia-selective antitumor agents. 5. Synthesis of water-soluble nitroaniline mustards with selective cytotoxicity for hypoxic mammalian cells.
    Journal of medicinal chemistry, 1992, Aug-21, Volume: 35, Issue:17

    Topics: Aniline Compounds; Aniline Mustard; Animals; Antineoplastic Agents; Cell Survival; Chemical Phenomena; Chemistry, Physical; CHO Cells; Cricetinae; Humans; Molecular Structure; Mustard Compounds; NAD(P)H Dehydrogenase (Quinone); Oxidation-Reduction; Oxygen; Rats; Solubility; Structure-Activity Relationship; Tumor Cells, Cultured; Water

1992
Hypoxia-selective antitumor agents. 9. Structure-activity relationships for hypoxia-selective cytotoxicity among analogues of 5-[N,N-bis(2-chloroethyl)amino]-2,4-dinitrobenzamide.
    Journal of medicinal chemistry, 1994, Jul-08, Volume: 37, Issue:14

    Topics: Aniline Mustard; Animals; Antineoplastic Agents; Cell Hypoxia; CHO Cells; Cricetinae; NAD(P)H Dehydrogenase (Quinone); Rats; Structure-Activity Relationship

1994
Hypoxia-selective antitumor agents. 14. Synthesis and hypoxic cell cytotoxicity of regioisomers of the hypoxia-selective cytotoxin 5-[N,N-bis(2-chloroethyl)amino]-2,4-dinitrobenzamide.
    Journal of medicinal chemistry, 1996, Jun-21, Volume: 39, Issue:13

    Topics: Aniline Mustard; Animals; Antineoplastic Agents; Cell Division; Cell Hypoxia; Cell Line; Cell Survival; Cricetinae; Cricetulus; Crystallography, X-Ray; Isomerism; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Inbred C3H; Molecular Structure; Structure-Activity Relationship; Tumor Cells, Cultured

1996
Synthesis and hypoxia-selective cytotoxicity of a 2-nitroimidazole mustard.
    Bioorganic & medicinal chemistry letters, 1998, Jul-07, Volume: 8, Issue:13

    Topics: Aniline Mustard; Animals; Antineoplastic Agents; Cell Hypoxia; Cell Line; Cricetinae; Cricetulus; Nitroimidazoles; Tumor Cells, Cultured

1998
Synthesis and structure-activity relationships for 2,4-dinitrobenzamide-5-mustards as prodrugs for the Escherichia coli nfsB nitroreductase in gene therapy.
    Journal of medicinal chemistry, 2007, Mar-22, Volume: 50, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Bystander Effect; Cell Line, Tumor; Drug Screening Assays, Antitumor; Enzyme Activation; Escherichia coli Proteins; Female; Genetic Therapy; Humans; Least-Squares Analysis; Male; Mice; Mice, Nude; Multivariate Analysis; Nitrogen Mustard Compounds; Nitroreductases; Prodrugs; Quantitative Structure-Activity Relationship; Transplantation, Heterologous

2007