Page last updated: 2024-09-03

sl 84.0418 and pyrroles

sl 84.0418 has been researched along with pyrroles in 11 studies

Compound Research Comparison

Studies (sl 84.0418)	Trials (sl 84.0418)	Recent Studies (post-2010) (sl 84.0418)	Studies (pyrroles)	Trials (pyrroles)	Recent Studies (post-2010) (pyrroles)
11	1	0	26,129	2,815	12,100

Research

Studies (11)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	10 (90.91)	18.2507
2000's	1 (9.09)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Angel, I; Arbilla, S; Berry, C; Galzin, AM; Langer, SZ; Niddam, R; Pimoule, C; Schoemaker, H; Sevrin, M; Wick, A	1
Colafranceschi, C; Guinebault, P; McAnena-Morice, D; Rouchouse, A	1
Angel, I; Langer, SZ	1
Angel, I; Garcia-Barrado, MJ; Henquin, JC; Jonas, JC	1
Berlin, I; Blacker, C; Cesselin, F; Chalon, S; Fuseau, E; Landault, C; Puech, AJ; Rosenzweig, P	1
Angel, I; Henquin, JC; Jonas, JC; Langer, SZ; Plant, TD	1
Angel, I; Grosset, A; Langer, SZ; Perrault, G; Schoemaker, H	1
Angel, I; Burcelin, R; Girard, J; Langer, SZ; Prouteau, M	1
Dan, K; Hirose, H; Maruyama, H; Nakamura, K; Saruta, T; Seto, Y	1
Angel, I; Coste, A; Eon, MT; Guillot, E	1
Capasso, A; Loizzo, A	1

Trials

1 trial(s) available for sl 84.0418 and pyrroles

Article	Year
Reduction of hyperglycemia after oral glucose load by the new alpha 2-adrenergic receptor antagonist SL 84.0418 in healthy subjects. Clinical pharmacology and therapeutics, 1994, Volume: 55, Issue:3 Topics: Administration, Oral; Adrenergic alpha-Antagonists; Adult; Blood Glucose; C-Peptide; Catecholamines; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Glipizide; Glucagon; Glucose Tolerance Test; Humans; Hypoglycemic Agents; Indoles; Insulin; Male; Pyrroles; Reference Values	1994

Article

Year

Reduction of hyperglycemia after oral glucose load by the new alpha 2-adrenergic receptor antagonist SL 84.0418 in healthy subjects.

Clinical pharmacology and therapeutics, 1994, Volume: 55, Issue:3

Topics: Administration, Oral; Adrenergic alpha-Antagonists; Adult; Blood Glucose; C-Peptide; Catecholamines; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Glipizide; Glucagon; Glucose Tolerance Test; Humans; Hypoglycemic Agents; Indoles; Insulin; Male; Pyrroles; Reference Values

1994

Other Studies

10 other study(ies) available for sl 84.0418 and pyrroles

Article	Year
SL 84.0418: a novel, potent and selective alpha-2 adrenoceptor antagonist: in vitro pharmacological profile. The Journal of pharmacology and experimental therapeutics, 1992, Volume: 263, Issue:3 Topics: Adrenergic alpha-Antagonists; Animals; Binding Sites; Cricetinae; Dogs; In Vitro Techniques; Indoles; Ion Channels; Lipolysis; Male; Mesocricetus; Norepinephrine; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyrroles; Rabbits; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha	1992
Plasma determination of the enantiomers of SL 84.0418, a new antihyperglycaemic drug, by HPLC on a chiral alpha 1-AGP column. Chirality, 1992, Volume: 4, Issue:2 Topics: Adrenergic alpha-Antagonists; Chromatography, High Pressure Liquid; Drug Stability; Humans; Hyperglycemia; Indoles; Orosomucoid; Pyrroles; Reproducibility of Results; Stereoisomerism	1992
Pre- and postsynaptic alpha-2 adrenoceptors as target for drug discovery. Journal of neural transmission. Supplementum, 1991, Volume: 34 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Azepines; Dioxanes; Dogs; Hyperglycemia; Hypoglycemic Agents; Hypothalamus; Idazoxan; In Vitro Techniques; Indoles; Insulin; Insulin Secretion; Islets of Langerhans; Male; Muscle Contraction; Muscle, Smooth; Muscle, Smooth, Vascular; Norepinephrine; Pyrroles; Rats; Receptors, Adrenergic, alpha; Synapses	1991
The imidazoline SL 84.0418 shows stereoselectivity in blocking alpha 2-adrenoceptors but not ATP-sensitive K+ channels in pancreatic B-cells. European journal of pharmacology, 1994, Oct-13, Volume: 264, Issue:1 Topics: Adenosine Triphosphate; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Diazoxide; Female; Glucose; Indoles; Insulin; Islets of Langerhans; Mice; Potassium; Potassium Channels; Pyrroles; Stereoisomerism	1994
In vitro stimulation of insulin release by SL 84.0418, a new alpha 2-adrenoceptor antagonist. European journal of pharmacology, 1994, Mar-11, Volume: 254, Issue:1-2 Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Diazoxide; Dioxanes; Electrophysiology; Female; Glucose; Idazoxan; In Vitro Techniques; Indoles; Insulin; Islets of Langerhans; Mice; Potassium Channels; Pyrroles; Rubidium Radioisotopes; Tolbutamide	1994
In vivo pharmacological profile of SL 84.0418, a new selective, peripherally active alpha 2-adrenoceptor antagonist. European journal of pharmacology, 1993, Apr-06, Volume: 234, Issue:2-3 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blood Glucose; Blood Pressure; Brimonidine Tartrate; Clonidine; Decerebrate State; Dioxanes; Epinephrine; Heart Rate; Hyperglycemia; Idazoxan; Indoles; Male; Mice; Motor Activity; Norepinephrine; Peripheral Nerves; Prazosin; Pyrroles; Quinoxalines; Rats; Rats, Sprague-Dawley; Stereoisomerism; Vasoconstriction	1993
Normalization of insulin secretion by a selective alpha 2-adrenoceptor antagonist restores GLUT-4 glucose transporter expression in adipose tissue of type II diabetic rats. Endocrinology, 1996, Volume: 137, Issue:5 Topics: Adipose Tissue; Adipose Tissue, Brown; Adrenergic alpha-Antagonists; Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Gene Expression; Glucose Tolerance Test; Glucose Transporter Type 4; Indoles; Insulin; Insulin Secretion; Monosaccharide Transport Proteins; Muscle Proteins; Muscle, Skeletal; Myocardium; Pyrroles; Rats; Rats, Wistar; RNA, Messenger	1996
Effects of alpha 2-adrenergic agonism, imidazolines, and G-protein on insulin secretion in beta cells. Metabolism: clinical and experimental, 1997, Volume: 46, Issue:10 Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Cricetinae; Glucose; GTP-Binding Proteins; Humans; Imidazoles; Indoles; Insulin; Insulin Secretion; Insulinoma; Islets of Langerhans; Kinetics; Molecular Structure; Oxymetazoline; Pancreatic Neoplasms; Pertussis Toxin; Phentolamine; Pyrroles; Quinolizines; Receptors, Adrenergic, alpha-2; Tumor Cells, Cultured; Virulence Factors, Bordetella	1997
Mechanisms of the hypoglycemic effects of the alpha2-adrenoceptor antagonists SL84.0418 and deriglidole. Life sciences, 1998, Volume: 62, Issue:9 Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Blood Glucose; Chlorisondamine; Diabetes Mellitus, Experimental; Diazoxide; Female; Glucose Tolerance Test; Hypoglycemic Agents; Imidazoles; Indoles; Insulin; Insulin Antagonists; Insulin Secretion; Male; Mice; Norepinephrine; Propranolol; Pyrroles; Rats; Rats, Sprague-Dawley; Species Specificity	1998
Alpha2-adrenoceptor antagonist SL 84.0418 reduces the expression of neocortical spike-and-wave spindling episodes in DBA/2J mice. Progress in neuro-psychopharmacology & biological psychiatry, 2003, Volume: 27, Issue:1 Topics: Animals; Disease Models, Animal; Electroencephalography; Indoles; Male; Mice; Mice, Inbred DBA; Neocortex; Pyrroles; Receptors, Adrenergic, alpha	2003