sl 84.0418 has been researched along with idazoxan in 3 studies
| Studies (sl 84.0418) | Trials (sl 84.0418) | Recent Studies (post-2010) (sl 84.0418) | Studies (idazoxan) | Trials (idazoxan) | Recent Studies (post-2010) (idazoxan) |
|---|---|---|---|---|---|
| 11 | 1 | 0 | 1,499 | 40 | 123 |
| Protein | Taxonomy | sl 84.0418 (IC50) | idazoxan (IC50) |
|---|---|---|---|
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 0.0083 | |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0195 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 0.0195 | |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | 0.0537 | |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0195 | |
| Alpha-1A adrenergic receptor | Homo sapiens (human) | 2.884 | |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0195 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Angel, I; Langer, SZ | 1 |
| Angel, I; Henquin, JC; Jonas, JC; Langer, SZ; Plant, TD | 1 |
| Angel, I; Grosset, A; Langer, SZ; Perrault, G; Schoemaker, H | 1 |
3 other study(ies) available for sl 84.0418 and idazoxan
| Article | Year |
|---|---|
Pre- and postsynaptic alpha-2 adrenoceptors as target for drug discovery.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Azepines; Dioxanes; Dogs; Hyperglycemia; Hypoglycemic Agents; Hypothalamus; Idazoxan; In Vitro Techniques; Indoles; Insulin; Insulin Secretion; Islets of Langerhans; Male; Muscle Contraction; Muscle, Smooth; Muscle, Smooth, Vascular; Norepinephrine; Pyrroles; Rats; Receptors, Adrenergic, alpha; Synapses | 1991 |
In vitro stimulation of insulin release by SL 84.0418, a new alpha 2-adrenoceptor antagonist.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Diazoxide; Dioxanes; Electrophysiology; Female; Glucose; Idazoxan; In Vitro Techniques; Indoles; Insulin; Islets of Langerhans; Mice; Potassium Channels; Pyrroles; Rubidium Radioisotopes; Tolbutamide | 1994 |
In vivo pharmacological profile of SL 84.0418, a new selective, peripherally active alpha 2-adrenoceptor antagonist.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blood Glucose; Blood Pressure; Brimonidine Tartrate; Clonidine; Decerebrate State; Dioxanes; Epinephrine; Heart Rate; Hyperglycemia; Idazoxan; Indoles; Male; Mice; Motor Activity; Norepinephrine; Peripheral Nerves; Prazosin; Pyrroles; Quinoxalines; Rats; Rats, Sprague-Dawley; Stereoisomerism; Vasoconstriction | 1993 |