sk&f 99085 has been researched along with ketoconazole in 1 studies
| Studies (sk&f 99085) | Trials (sk&f 99085) | Recent Studies (post-2010) (sk&f 99085) | Studies (ketoconazole) | Trials (ketoconazole) | Recent Studies (post-2010) (ketoconazole) |
|---|---|---|---|---|---|
| 15 | 2 | 3 | 149 | 0 | 120 |
| Protein | Taxonomy | sk&f 99085 (IC50) | ketoconazole (IC50) |
|---|---|---|---|
| Bile salt export pump | Homo sapiens (human) | 3.4 | |
| Steroid 17-alpha-hydroxylase/17,20 lyase | Homo sapiens (human) | 1.175 | |
| Epoxide hydrolase 1 | Homo sapiens (human) | 0.04 | |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | 1.058 | |
| Cytochrome P450 3A4 | Homo sapiens (human) | 0.2303 | |
| Cytochrome P450 2D6 | Homo sapiens (human) | 2.774 | |
| Aromatase | Homo sapiens (human) | 1.3026 | |
| Cytochrome P450 11B1, mitochondrial | Homo sapiens (human) | 0.4519 | |
| Cytochrome P450 11B2, mitochondrial | Homo sapiens (human) | 0.1272 | |
| Cytochrome P450 3A5 | Homo sapiens (human) | 0.2535 | |
| Bifunctional epoxide hydrolase 2 | Homo sapiens (human) | 0.04 | |
| 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial | Homo sapiens (human) | 0.3 | |
| Sterol 14-alpha demethylase | Trypanosoma cruzi strain CL Brener | 0.014 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hashimoto, Y; Ohgane, K; Sagimori, I; Yoshioka, H | 1 |
1 other study(ies) available for sk&f 99085 and ketoconazole
| Article | Year |
|---|---|
Luciferase-based HMG-CoA reductase degradation assay for activity and selectivity profiling of oxy(lano)sterols.
Topics: HEK293 Cells; Humans; Hydroxymethylglutaryl CoA Reductases; Lanosterol; Molecular Structure; Oxysterols; Sterol Regulatory Element Binding Proteins; Structure-Activity Relationship | 2020 |