Page last updated: 2024-08-16

sk&f 97541 and 3-aminopropylphosphinic acid

sk&f 97541 has been researched along with 3-aminopropylphosphinic acid in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (42.86)18.2507
2000's2 (28.57)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baumann, PA; Brugger, F; Froestl, W; Gentsch, C; Hall, RG; Jaekel, J; Mickel, SJ; Olpe, HR; Strub, D; von Sprecher, G1
Baumann, PA; Bernasconi, R; Diel, PJ; Froestl, W; Hall, RG; Maier, L; Melillo, V; Mickel, SJ; Strub, D; von Sprecher, G1
Alstermark, C; Amin, K; Dinn, SR; Elebring, T; Fitzpatrick, K; Fjellström, O; Geiss, WB; Gottfries, J; Guzzo, PR; Harding, JP; Holmén, A; Kothare, M; Lehmann, A; Mattsson, JP; Nilsson, K; Sundén, G; Swanson, M; von Unge, S; Woo, AM; Wyle, MJ; Zheng, X1
Annamalai, T; Chen, JL; Chernov-Rogan, T; Dilip, U; Gallop, MA; Grindstaff, K; Koller, K; Peng, G; Phan, T; Wustrow, DJ; Xu, F; Zhang, X1
Howson, W; Lacey, MG; Seabrook, GR1
Farb, DH; Gravielle, MC; Lyons, HR; Martin, SC; Russek, SJ; Steiger, JL1
Antonsson, M; Aurell-Holmberg, A; Blackshaw, LA; Brändén, L; Elebring, T; Jensen, J; Kärrberg, L; Lehmann, A; Mattsson, JP; Nilsson, K; Oja, SS; Saransaari, P; von Unge, S1

Other Studies

7 other study(ies) available for sk&f 97541 and 3-aminopropylphosphinic acid

ArticleYear
Phosphinic acid analogues of GABA. 1. New potent and selective GABAB agonists.
    Journal of medicinal chemistry, 1995, Aug-18, Volume: 38, Issue:17

    Topics: Animals; Behavior, Animal; Cats; Crystallography, X-Ray; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; In Vitro Techniques; Magnetic Resonance Spectroscopy; Male; Organophosphonates; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Stereoisomerism; Structure-Activity Relationship

1995
Phosphinic acid analogues of GABA. 2. Selective, orally active GABAB antagonists.
    Journal of medicinal chemistry, 1995, Aug-18, Volume: 38, Issue:17

    Topics: Administration, Oral; Amnesia; Animals; Cerebral Cortex; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Learning; Long-Term Potentiation; Magnetic Resonance Spectroscopy; Phosphinic Acids; Protein Binding; Radioligand Assay; Rats; Receptors, GABA-B; Structure-Activity Relationship

1995
Synthesis and pharmacological evaluation of novel gamma-aminobutyric acid type B (GABAB) receptor agonists as gastroesophageal reflux inhibitors.
    Journal of medicinal chemistry, 2008, Jul-24, Volume: 51, Issue:14

    Topics: Animals; Dose-Response Relationship, Drug; GABA Agonists; GABA-B Receptor Agonists; Gastroesophageal Reflux; Humans; Magnetic Resonance Spectroscopy; Spectrometry, Mass, Fast Atom Bombardment

2008
Discovery of a novel potent GABA(B) receptor agonist.
    Bioorganic & medicinal chemistry letters, 2011, Nov-01, Volume: 21, Issue:21

    Topics: Animals; Baclofen; Blood-Brain Barrier; Drug Discovery; GABA Agonists; Humans; Mice; Receptors, GABA-B

2011
Electrophysiological characterization of potent agonists and antagonists at pre- and postsynaptic GABAB receptors on neurones in rat brain slices.
    British journal of pharmacology, 1990, Volume: 101, Issue:4

    Topics: Animals; Baclofen; Bicuculline; Brain; Corpus Striatum; Electrophysiology; GABA-A Receptor Antagonists; In Vitro Techniques; Membrane Potentials; Neurons; Organophosphorus Compounds; Rats; Receptors, GABA-A; Substantia Nigra; Synapses

1990
Differential expression of gamma-aminobutyric acid type B receptor subunit mRNAs in the developing nervous system and receptor coupling to adenylyl cyclase in embryonic neurons.
    The Journal of comparative neurology, 2004, May-17, Volume: 473, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Baclofen; Binding Sites; Blotting, Western; Chlorocebus aethiops; COS Cells; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; GABA Agonists; gamma-Aminobutyric Acid; Gene Expression Regulation, Developmental; In Situ Hybridization; Inhibitory Concentration 50; Male; Nervous System; Neurons; Organophosphorus Compounds; Phosphodiesterase Inhibitors; Protein Subunits; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transfection; Tritium

2004
Different in vitro and in vivo profiles of substituted 3-aminopropylphosphinate and 3-aminopropyl(methyl)phosphinate GABA(B) receptor agonists as inhibitors of transient lower oesophageal sphincter relaxation.
    British journal of pharmacology, 2012, Volume: 165, Issue:6

    Topics: Animals; Brain; Cerebral Cortex; CHO Cells; Cricetinae; Cricetulus; Dogs; Esophageal Sphincter, Lower; Female; GABA-B Receptor Agonists; Humans; Hypothermia; In Vitro Techniques; Mice; Mice, Inbred C57BL; Muscle Relaxation; Organophosphorus Compounds; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, GABA-A; Receptors, GABA-B

2012