sk&f 95282 has been researched along with piperidines in 47 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (12.77) | 18.7374 |
| 1990's | 28 (59.57) | 18.2507 |
| 2000's | 6 (12.77) | 29.6817 |
| 2010's | 7 (14.89) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bodnar, RJ; Hough, LB; Koch, JE | 1 |
| Hough, LB; Nalwalk, JW | 2 |
| Chakravarty, AK; Puri, S; Ray, A; Sen, P | 1 |
| Maeyama, K; Onodera, K; Sakai, N; Watanabe, T; Yanai, K | 1 |
| Boussard, M; Jantos, H; Monti, JM; Olivera, S; Orellana, C | 1 |
| Battles, AH; Hough, LB; Nalwalk, JW | 1 |
| Eberle, NB; Glick, SD; Gogas, KR; Hough, LB; Lyon, RA; Parsons, ME; Ward, SJ; Young, RC | 1 |
| Gogas, KR; Hough, LB | 3 |
| Calcutt, CR; Ganellin, CR; Griffiths, R; Leigh, BK; Maguire, JP; Mitchell, RC; Mylek, ME; Parsons, ME; Smith, IR; Young, RC | 1 |
| Camarota, NA; Cue, D; Eberle, N; Gogas, KR; Hough, LB; Jackowski, S | 1 |
| Imaizumi, M; Miyazaki, S; Onodera, K | 2 |
| Fleckenstein, AE; Lookingland, KJ; Moore, KE | 2 |
| Wong, CL | 1 |
| Barke, KE; Bodnar, RJ; Hough, LB; Koch, JE; Nalwalk, JW | 1 |
| Misawa, M; Onodera, K; Suzuki, T; Takamori, K | 1 |
| Adami, M; Bertaccini, G; Coruzzi, G; Poli, E; Pozzoli, C | 1 |
| Schilling, L; Wahl, M | 1 |
| Adachi, N; Hirakawa, M; Itano, Y; Oishi, R; Saeki, K; Yamada, T | 1 |
| D'Souza, T; Dryer, SE; Nowak, JZ; Sek, B | 1 |
| Eaton, SJ; Eoh, S; Harrington, ME; Hoque, S; Meyer, J | 1 |
| Ito, C; Onodera, K; Sato, M; Watanabe, T | 1 |
| Hayashi, Y; Kagawa, K; Mammoto, T; Mashimo, T; Yamamoto, Y; Yamatodani, A; Yoshiya, I | 1 |
| Imaizumi, M; Miyazaki, S; Onodera, K; Timmerman, H | 1 |
| Itoh, C; Onodera, K; Sato, M; Watanabe, T | 1 |
| Misawa, M; Mori, T; Onodera, K; Suzuki, T; Tsuji, M | 1 |
| Bertaccini, G; Coppelli, G; Coruzzi, G; Poli, E; Pozzoli, C | 1 |
| Inokuchi, A; Komiyama, S; Liu, F; Ureshino, M; Yokomitsu, S | 1 |
| Meade, HM; Seeley, NA; Sturman, G | 1 |
| Chen, Z; Fujii, Y; Kamei, C; Sugimoto, Y; Suzuki, G | 1 |
| Affricano, D; Angelucci, L; Lombardo, K; Nicolai, R; Scaccianoce, S | 1 |
| Hough, LB; Lu, Q; Montero, MJ; Nalwalk, JW; Shan, Z; Svokos, K; Wentland, MP | 1 |
| Kuramasu, A; Mobarakeh, JI; Sakurada, S; Takahashi, K; Yanai, K | 1 |
| Krishna, DR; Kumar, KV; Palit, G | 1 |
| Chen, Z; Dai, HB; Fu, QL; Shen, Y | 1 |
| Chen, Z; Dai, H; Fan, Y; Fu, Q; Hu, W; Shen, Y; Zhang, W | 1 |
| Hasanein, P | 1 |
| Canto-de-Souza, A; Kishi, MS; Mattioli, R; Serafim, KR | 1 |
| Jin, CY; Pertovaara, A; Viisanen, H; Wei, H; You, HJ | 1 |
| Darras, FH; Decker, M; Khan, N; Nurulain, SM; Saad, A; Sadek, B | 1 |
| Kieć-Kononowiczc, K; Saad, A; Sadek, B; Shafiullah, M; Subramanian, D; Łażewska, D | 1 |
| Baldi, E; Blandina, P; Bucherelli, C; Costa, A; Fabbri, R; Munari, L; Passani, MB; Provensi, G | 1 |
| Alachkar, A; Gryboś, A; Handzlik, J; Honkisz, E; Kiec-Kononowicz, K; Latacz, G; Lubelska, A; Sadek, B; Siwek, A; Stark, H; Łażewska, D | 1 |
47 other study(ies) available for sk&f 95282 and piperidines
| Article | Year |
|---|---|
Potentiation of 2-deoxy-D-glucose antinociception, but not hyperphagia by zolantidine, a histamine (H2) receptor antagonist.
Topics: Animals; Benzothiazoles; Deoxyglucose; Histamine H2 Antagonists; Hot Temperature; Hyperphagia; Male; Nociceptors; Phenoxypropanolamines; Piperidines; Rats; Rats, Inbred Strains; Thiazoles | 1992 |
Inhibition of morphine antinociception by centrally administered histamine H2 receptor antagonists.
Topics: Animals; Benzothiazoles; Brain; Cimetidine; Histamine H2 Antagonists; Injections, Intraventricular; Male; Morphine; Nociceptors; Phenoxypropanolamines; Piperidines; Rats; Rats, Inbred Strains; Receptors, Histamine H2; Thiazoles | 1992 |
Central histaminergic involvement during stress in rats.
Topics: Animals; Antibody Formation; Benzothiazoles; Brain; Corticosterone; Histamine; Histamine H2 Antagonists; Histidine Decarboxylase; Male; Methylhistidines; Peptic Ulcer; Pheniramine; Phenoxypropanolamines; Piperidines; Rats; Rats, Wistar; Stress, Physiological; Thiazoles | 1992 |
Effects of thioperamide, a histamine H3 receptor antagonist, on locomotor activity and brain histamine content in mast cell-deficient W/Wv mice.
Topics: Animals; Benzothiazoles; Brain Chemistry; Dopamine; Histamine; Histamine Antagonists; Histamine H2 Antagonists; Mast Cells; Methylhistamines; Mice; Mice, Mutant Strains; Motor Activity; Phenoxypropanolamines; Piperidines; Pyrilamine; Receptors, Histamine H3; Thiazoles | 1991 |
Sleep variables are unaltered by zolantidine in rats: are histamine H2-receptors not involved in sleep regulation?
Topics: Animals; Benzothiazoles; Diphenhydramine; Dose-Response Relationship, Drug; Histamine H2 Antagonists; Male; Phenoxypropanolamines; Piperidines; Rats; Rats, Inbred Strains; Receptors, Histamine H2; Reference Values; Sleep; Thiazoles; Time Factors; Wakefulness | 1990 |
Zolantidine-induced attenuation of morphine antinociception in rhesus monkeys.
Topics: Animals; Benzothiazoles; Dose-Response Relationship, Drug; Double-Blind Method; Female; Histamine H2 Antagonists; Macaca mulatta; Morphine; Pain; Phenoxypropanolamines; Piperidines; Thiazoles | 1990 |
A role for histamine and H2-receptors in opioid antinociception.
Topics: Analgesia; Animals; Benzothiazoles; Cimetidine; Histamine; Male; Morphine; Phenoxypropanolamines; Piperidines; Ranitidine; Rats; Rats, Inbred Strains; Receptors, Histamine H2; Receptors, Opioid; Thiazoles | 1989 |
Inhibition of naloxone-resistant antinociception by centrally administered H2-antagonists.
Topics: Analgesia; Animals; Benzothiazoles; Brain; Dose-Response Relationship, Drug; Drug Resistance; Histamine; Histamine H2 Antagonists; Male; Naloxone; Phenoxypropanolamines; Piperidines; Rats; Rats, Inbred Strains; Thiazoles | 1989 |
Zolantidine (SK&F 95282) is a potent selective brain-penetrating histamine H2-receptor antagonist.
Topics: Animals; Benzothiazoles; Binding, Competitive; Brain Chemistry; Cimetidine; Cyclic AMP; Female; Guinea Pigs; Hippocampus; Histamine H2 Antagonists; In Vitro Techniques; Male; Phenoxypropanolamines; Piperidines; Rats; Thiazoles; Uterus | 1988 |
Effects of zolantidine a brain-penetrating H2-receptor antagonist, on naloxone-sensitive and naloxone-resistant analgesia.
Topics: Analgesia; Animals; Benzothiazoles; Brain; Drug Interactions; Drug Resistance; Histamine H2 Antagonists; Male; Naloxone; Phenoxypropanolamines; Piperidines; Rats; Rats, Inbred Strains; Thiazoles | 1988 |
H2-receptor-mediated stress-induced analgesia is dependent on neither pituitary nor adrenal activation.
Topics: Adrenalectomy; Analgesia; Animals; Benzothiazoles; Electroshock; Histamine H2 Antagonists; Hypophysectomy; Male; Naloxone; Phenoxypropanolamines; Piperidines; Rats; Rats, Inbred Strains; Receptors, Histamine H2; Reference Values; Thiazoles | 1988 |
Actions of the brain-penetrating H2-antagonist zolantidine on histamine dynamics and metabolism in rat brain.
Topics: Animals; Benzothiazoles; Brain; Brain Chemistry; Dose-Response Relationship, Drug; Histamine; Histamine N-Methyltransferase; In Vitro Techniques; Kidney; Kinetics; Methylhistamines; Methyltransferases; Phenoxypropanolamines; Piperidines; Rats; Rats, Inbred Strains; Thiazoles | 1988 |
Effects of thioperamide, a histamine H3-receptor antagonist, on a scopolamine-induced learning deficit using an elevated plus-maze test in mice.
Topics: Animals; Benzothiazoles; Histamine; Histamine Antagonists; Male; Maze Learning; Mice; Mice, Inbred ICR; Phenoxypropanolamines; Piperidines; Scopolamine; Thiazoles | 1995 |
Histaminergic neurons mediate restraint stress-induced activation of central 5-hydroxytryptaminergic neurons in the rat.
Topics: Animals; Benzothiazoles; Histamine; Histamine H2 Antagonists; Histidine Decarboxylase; Hydroxyindoleacetic Acid; Male; Methylhistidines; Neurons; Nucleus Accumbens; Phenoxypropanolamines; Piperidines; Pyrilamine; Rats; Receptors, Histamine H1; Restraint, Physical; Serotonin; Suprachiasmatic Nucleus; Thiazoles | 1994 |
Effects of a histamine H2 receptor agonist and antagonist on restraint-induced antinociception in female mice.
Topics: Animals; Benzothiazoles; Cimetidine; Dimaprit; Female; Histamine Agonists; Histamine H2 Antagonists; Mice; Mice, Inbred Strains; Pain Measurement; Phenoxypropanolamines; Piperidines; Reaction Time; Restraint, Physical; Stress, Psychological; Thiazoles | 1995 |
Modulation of morphine antinociception by the brain-penetrating H2 antagonist zolantidine: detailed characterization in five nociceptive test systems.
Topics: Animals; Benzothiazoles; Blood-Brain Barrier; Histamine H2 Antagonists; Hot Temperature; Male; Morphine; Pain; Pain Measurement; Phenoxypropanolamines; Piperidines; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Thiazoles | 1995 |
Importance of histamine H2 receptors in restraint-morphine interactions.
Topics: Analysis of Variance; Animals; Benzothiazoles; Histamine; Histamine H2 Antagonists; Male; Morphine; Pain; Phenoxypropanolamines; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Histamine H2; Restraint, Physical; Thiazoles; Time Factors | 1995 |
Effects of the histaminergic system on the morphine-induced conditioned place preference in mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benzazepines; Benzothiazoles; Conditioning, Operant; Dihydroxyphenylalanine; Dopamine; Dose-Response Relationship, Drug; Histamine; Histamine H2 Antagonists; Histidine; Histidine Decarboxylase; Homovanillic Acid; Limbic System; Male; Methylhistidines; Mice; Mice, Inbred Strains; Morphine; Phenoxypropanolamines; Piperidines; Prosencephalon; Thiazoles | 1995 |
Activity of the new histamine H2-receptor antagonist zolantidine at cardiac and gastric H2-receptors.
Topics: Animals; Benzothiazoles; Cats; Female; Gastric Fistula; Gastric Mucosa; Guinea Pigs; Heart Rate; Histamine H2 Antagonists; Male; Myocardial Contraction; Phenoxypropanolamines; Piperidines; Ranitidine; Rats; Rats, Wistar; Thiazoles | 1994 |
Activation of noradrenergic neurons projecting to the diencephalon following central administration of histamine is mediated by H1 receptors.
Topics: Animals; Benzothiazoles; Cerebral Ventricles; Diencephalon; Histamine; Histamine H2 Antagonists; Injections, Intraventricular; Male; Methoxyhydroxyphenylglycol; Neurons; Norepinephrine; Paraventricular Hypothalamic Nucleus; Phenoxypropanolamines; Piperidines; Preoptic Area; Pyrilamine; Rats; Receptors, Histamine H1; Thiazoles | 1994 |
Effects of antihistaminics on experimental brain edema.
Topics: Animals; Antioxidants; Benzothiazoles; Blood-Brain Barrier; Brain Edema; Dexamethasone; Freezing; Histamine; Histamine Antagonists; Histamine H2 Antagonists; Lipid Peroxidation; Male; Parietal Lobe; Phenoxypropanolamines; Piperidines; Pregnatrienes; Pyrilamine; Rats; Rats, Sprague-Dawley; Thiazoles; Water-Electrolyte Balance | 1994 |
Aggravation of ischemic neuronal damage in the rat hippocampus by impairment of histaminergic neurotransmission.
Topics: Animals; Benzothiazoles; Brain Ischemia; Cell Death; Hippocampus; Histamine Agonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Male; Methylhistamines; Methylhistidines; Neurons; Phenoxypropanolamines; Piperidines; Pyrilamine; Rats; Rats, Wistar; Receptors, Histamine; Synaptic Transmission; Thiazoles | 1993 |
Does histamine stimulate cyclic AMP formation in the avian pineal gland via a novel (non-H1, non-H2, non-H3) histamine receptor subtype.
Topics: Animals; Benzothiazoles; Chickens; Cyclic AMP; Ducks; Histamine; Histamine Agonists; Histamine H2 Antagonists; Ion Channels; Male; Methylation; Phenoxypropanolamines; Pineal Gland; Piperidines; Receptors, Histamine; Stimulation, Chemical; Thiazoles | 1995 |
Circadian rhythm photic phase shifts are not altered by histamine receptor antagonists.
Topics: Animals; Benzothiazoles; Cimetidine; Circadian Rhythm; Cricetinae; Histamine Antagonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Male; Mesocricetus; Phenoxypropanolamines; Photoperiod; Piperidines; Pyrilamine; Receptors, Histamine H3; Thiazoles | 1996 |
Effects of histamine agents on methamphetamine-induced stereotyped behavior and behavioral sensitization in rats.
Topics: Animals; Benzothiazoles; Brain; Central Nervous System Stimulants; Histamine Agents; Histidine; Male; Methamphetamine; Methylhistidines; Motor Activity; Phenoxypropanolamines; Piperidines; Pyrilamine; Rats; Rats, Wistar; Receptors, Histamine; Stereotyped Behavior; Thiazoles | 1997 |
Interactions between neuronal histamine and halothane anesthesia in rats.
Topics: Anesthetics, Inhalation; Animals; Benzothiazoles; Drug Interactions; Enzyme Inhibitors; Halothane; Histamine Antagonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Histamine Release; Male; Methylhistidines; Microdialysis; Neurons; Phenoxypropanolamines; Piperidines; Pyrilamine; Rats; Rats, Sprague-Dawley; Thiazoles | 1997 |
Effects of clobenpropit (VUF-9153), a histamine H3-receptor antagonist, on learning and memory, and on cholinergic and monoaminergic systems in mice.
Topics: Acetylcholine; Animals; Avoidance Learning; Benzothiazoles; Biogenic Monoamines; Brain; Drug Interactions; Histamine Antagonists; Histamine H2 Antagonists; Imidazoles; Male; Memory; Methylhistamines; Mice; Mice, Inbred ICR; Phenoxypropanolamines; Piperidines; Pyrilamine; Receptors, Histamine H1; Receptors, Histamine H3; Scopolamine; Thiazoles; Thiourea | 1997 |
Motor behavioural function for histamine-dopamine interaction in brain.
Topics: Animals; Benzazepines; Benzothiazoles; Brain; Brain Chemistry; Central Nervous System Stimulants; Dopamine Agents; Dopamine Antagonists; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Histidine; Methamphetamine; Motor Activity; Phenoxypropanolamines; Piperidines; Pyrilamine; Rats; Rats, Wistar; Stereotyped Behavior; Thiazoles | 1998 |
Cognitive involvement by negative modulation of histamine H2 receptors in passive avoidance task in mice.
Topics: Animals; Avoidance Learning; Benzothiazoles; Cognition; Drug Interactions; Histamine Agonists; Histamine H2 Antagonists; Injections, Intraventricular; Male; Memory; Methylhistamines; Mice; Mice, Inbred ICR; Phenoxypropanolamines; Piperidines; Receptors, Histamine H2; Thiazoles | 1998 |
Generalization of D-, L- and DL-chlorpheniramine and zolantidine to the discriminative stimulus effects of cocaine and methamphetamine.
Topics: Animals; Antidepressive Agents, Tricyclic; Benzothiazoles; Chlorpheniramine; Clomipramine; Cocaine; Desipramine; Discrimination, Psychological; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Generalization, Stimulus; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Male; Methamphetamine; Middle Aged; Phenoxypropanolamines; Piperazines; Piperidines; Rats; Rats, Inbred F344; Thiazoles | 1997 |
Effects of histamine H2 receptor agonists and antagonists on the isolated guinea pig gallbladder.
Topics: Animals; Benzothiazoles; Dopamine Agents; Famotidine; Gallbladder; Guanidines; Guinea Pigs; Histamine; Histamine Agonists; Histamine H2 Antagonists; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Phenoxypropanolamines; Piperidines; Pyridines; Receptors, Histamine H2; Sincalide; Thiazoles; Triazoles | 1999 |
Effects of the antihistaminergic drugs diphenhydramine and zolantidine on vestibular-induced hypothalamic neuronal activity in the guinea pig.
Topics: Animals; Benzothiazoles; Caloric Tests; Diphenhydramine; Guinea Pigs; Histamine H1 Antagonists; Hypothalamus; Injections, Intravenous; Male; Neurons; Phenoxypropanolamines; Piperidines; Thiazoles; Vestibule, Labyrinth | 1999 |
Histamine H2-receptor modulation in two mouse models of seizure susceptibility.
Topics: Acoustic Stimulation; Animals; Anticonvulsants; Benzothiazoles; Convulsants; Dimaprit; Female; Histamine Agonists; Histamine Antagonists; Male; Mice; Mice, Inbred DBA; Pentylenetetrazole; Phenoxypropanolamines; Piperidines; Receptors, Histamine H2; Seizures; Thiazoles | 1999 |
Effects of histamine and related compounds on regional cerebral blood flow in rats.
Topics: Animals; Benzothiazoles; Blood Pressure; Brain Chemistry; Dimaprit; Diphenhydramine; Drug Interactions; Hippocampus; Histamine; Histamine Agonists; Histamine Antagonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Histidine; Male; Phenoxypropanolamines; Piperidines; Pyrilamine; Rats; Rats, Wistar; Regional Blood Flow; Thiazoles; Time Factors | 1999 |
Studies on the involvement of histamine in the hypothalamic-pituitary-adrenal axis activation induced by nerve growth factor.
Topics: Adrenal Glands; Animals; Benzothiazoles; Catheterization; Corticosterone; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Hypothalamo-Hypophyseal System; Male; Metiamide; Mice; Nerve Growth Factor; Phenoxypropanolamines; Piperidines; Pituitary-Adrenal System; Promethazine; Rats; Rats, Wistar; Thiazoles | 2000 |
Antinociceptive, brain-penetrating derivatives related to improgan, a non-opioid analgesic.
Topics: Algorithms; Analgesics; Animals; Behavior, Animal; Benzothiazoles; Brain; Cimetidine; Dose-Response Relationship, Drug; Histamine H2 Antagonists; Injections, Intraventricular; Male; Mice; Molecular Structure; Pain; Pain Measurement; Phenoxypropanolamines; Piperidines; Quinazolines; Quinazolinones; Rats; Rats, Sprague-Dawley; Thiazoles; Time Factors; Triazoles | 2005 |
Enhanced antinociceptive effects of morphine in histamine H2 receptor gene knockout mice.
Topics: Analysis of Variance; Animals; Benzothiazoles; Brain; Capsaicin; Drug Synergism; Ganglia, Spinal; Histamine H2 Antagonists; Hot Temperature; Hyperalgesia; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Morphine; Narcotics; Pain Measurement; Phenoxypropanolamines; Piperidines; Reaction Time; Receptors, Histamine H2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Touch | 2006 |
Histaminergic H1 receptors mediate L-histidine-induced anxiety in elevated plus-maze test in mice.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Benzothiazoles; Diazepam; Dose-Response Relationship, Drug; Histamine Antagonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Histidine; Male; Mice; Phenoxypropanolamines; Piperidines; Pyrilamine; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H3 | 2007 |
[Reversing effect of histamine on neurotoxicity induced by beta-amyloid1-42].
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Benzothiazoles; Diphenhydramine; Dose-Response Relationship, Drug; Histamine; Histamine H2 Antagonists; Histamine H3 Antagonists; Imidazoles; Neuroprotective Agents; PC12 Cells; Phenoxypropanolamines; Piperidines; Rats; Receptors, Histamine H2; Receptors, Histamine H3; Thiourea | 2007 |
Carnosine protects against Abeta42-induced neurotoxicity in differentiated rat PC12 cells.
Topics: Amyloid beta-Peptides; Animals; Benzothiazoles; Carnosine; Cell Differentiation; Diphenhydramine; Drug Interactions; Glutamic Acid; Histamine H1 Antagonists; Histamine H2 Antagonists; Histamine H3 Antagonists; Imidazoles; Neurons; Neurotoxins; PC12 Cells; Peptide Fragments; Phenoxypropanolamines; Piperidines; Rats; Receptors, N-Methyl-D-Aspartate; Thiourea | 2008 |
Two histamine H2 receptor antagonists, zolantidine and cimetidine, modulate nociception in cholestatic rats.
Topics: Analgesia; Animals; Benzothiazoles; Cholestasis; Cimetidine; Dimaprit; Disease Models, Animal; Histamine H2 Antagonists; Male; Naloxone; Narcotic Antagonists; Pain; Pain Measurement; Pain Perception; Phenoxypropanolamines; Piperidines; Rats; Rats, Wistar; Receptors, Histamine H2; Rotarod Performance Test | 2011 |
H₁ but not H₂ histamine antagonist receptors mediate anxiety-related behaviors and emotional memory deficit in mice subjected to elevated plus-maze testing.
Topics: Animals; Anxiety; Benzothiazoles; Chlorpheniramine; Histamine H1 Antagonists; Histamine H2 Antagonists; Male; Maze Learning; Memory Disorders; Mice; Microinjections; Phenoxypropanolamines; Piperidines; Receptors, Histamine H1 | 2013 |
Histamine in the locus coeruleus promotes descending noradrenergic inhibition of neuropathic hypersensitivity.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic Neurons; Animals; Benzothiazoles; Bicuculline; GABA-A Receptor Antagonists; Histamine; Histamine H2 Antagonists; Hot Temperature; Hyperalgesia; Imidazoles; Indans; Locus Coeruleus; Male; Neuralgia; Phenoxypropanolamines; Physical Stimulation; Piperidines; Prazosin; Rats; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Receptors, Histamine; Spinal Nerves | 2014 |
The dual-acting H3 receptor antagonist and AChE inhibitor UW-MD-71 dose-dependently enhances memory retrieval and reverses dizocilpine-induced memory impairment in rats.
Topics: Animals; Avoidance Learning; Benzothiazoles; Cholinesterase Inhibitors; Disease Models, Animal; Dizocilpine Maleate; Donepezil; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Histamine H3 Antagonists; Indans; Male; Memory; Memory Disorders; Nootropic Agents; Phenoxypropanolamines; Piperidines; Pyrilamine; Pyrroles; Quinazolines; Random Allocation; Rats, Wistar; Receptors, Histamine H3 | 2016 |
Anticonvulsant and procognitive properties of the non-imidazole histamine H3 receptor antagonist DL77 in male adult rats.
Topics: Animals; Anticonvulsants; Avoidance Learning; Benzothiazoles; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Epilepsy; Histamine Agonists; Histamine H2 Antagonists; Histamine H3 Antagonists; Male; Memory; Methylhistamines; Nootropic Agents; Phenoxypropanolamines; Phenyl Ethers; Phenytoin; Piperidines; Random Allocation; Rats, Wistar; Receptors, Histamine H3 | 2016 |
Histaminergic Neurotransmission as a Gateway for the Cognitive Effect of Oleoylethanolamide in Contextual Fear Conditioning.
Topics: Analysis of Variance; Animals; Benzothiazoles; Cognition; Conditioning, Psychological; Endocannabinoids; Enzyme Inhibitors; Fear; Freezing Reaction, Cataleptic; Histamine; Histamine Agents; Hypothalamus; Male; Methylhistidines; Microdialysis; Oleic Acids; Phenoxypropanolamines; Piperidines; Rats; Rats, Wistar | 2017 |
Anticonvulsant evaluation of novel non-imidazole histamine H3R antagonists in different convulsion models in rats.
Topics: Animals; Anticonvulsants; Benzothiazoles; Disease Models, Animal; Dose-Response Relationship, Drug; Histamine H3 Antagonists; Humans; Male; Phenoxypropanolamines; Piperidines; Pyrilamine; Rats; Rats, Wistar; Reaction Time; Seizures; Strychnine | 2018 |