Page last updated: 2024-09-03

sk&f 89748 and yohimbine

sk&f 89748 has been researched along with yohimbine in 2 studies

Compound Research Comparison

Studies
(sk&f 89748)
Trials
(sk&f 89748)
Recent Studies (post-2010)
(sk&f 89748)
Studies
(yohimbine)
Trials
(yohimbine)
Recent Studies (post-2010) (yohimbine)
16005,893253532

Protein Interaction Comparison

ProteinTaxonomysk&f 89748 (IC50)yohimbine (IC50)
Alpha-2A adrenergic receptorHomo sapiens (human)0.0353
Cytochrome P450 2D6Homo sapiens (human)1.02
D(2) dopamine receptorHomo sapiens (human)2.06
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)1.3
Alpha-2B adrenergic receptorHomo sapiens (human)0.0428
Alpha-2C adrenergic receptorHomo sapiens (human)0.0466
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)0.126
Alpha-2B adrenergic receptorRattus norvegicus (Norway rat)0.0682
Alpha-2C adrenergic receptorRattus norvegicus (Norway rat)0.0682
Alpha-2A adrenergic receptorRattus norvegicus (Norway rat)0.0682
Alpha-1D adrenergic receptorRattus norvegicus (Norway rat)1.3
Alpha-1D adrenergic receptorHomo sapiens (human)1.013
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)0.126
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.074
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)1.3
5-hydroxytryptamine receptor 6Homo sapiens (human)1.689

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19902 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
DeMarinis, RM; Hieble, JP1
Fowler, PJ; Grous, M; Matthews, WD; Price, W1

Other Studies

2 other study(ies) available for sk&f 89748 and yohimbine

ArticleYear
l-1,2,3,4-Tetrahydro-8-methoxy-5-(methylthio)-2-naphthalenamine: a potent and selective agonist at alpha 1-adrenoceptors.
    Journal of medicinal chemistry, 1983, Volume: 26, Issue:9

    Topics: Adrenergic alpha-Agonists; Animals; Arteries; Crystallography; Naphthalenes; Norepinephrine; Rabbits; Stereoisomerism; Tetrahydronaphthalenes; Vasoconstriction; X-Rays

1983
Pharmacological differentiation of postsynaptic alpha adrenoceptors in the dog saphenous vein.
    The Journal of pharmacology and experimental therapeutics, 1984, Volume: 229, Issue:3

    Topics: Animals; Azepines; Dogs; Female; Male; Muscle Contraction; Muscle, Smooth, Vascular; Naphthols; Norepinephrine; Phenoxybenzamine; Prazosin; Receptors, Adrenergic, alpha; Saphenous Vein; Tetrahydronaphthalenes; Yohimbine

1984