sk&f 89748 has been researched along with clonidine in 4 studies
| Studies (sk&f 89748) | Trials (sk&f 89748) | Recent Studies (post-2010) (sk&f 89748) | Studies (clonidine) | Trials (clonidine) | Recent Studies (post-2010) (clonidine) |
|---|---|---|---|---|---|
| 16 | 0 | 0 | 13,692 | 2,044 | 1,394 |
| Protein | Taxonomy | sk&f 89748 (IC50) | clonidine (IC50) |
|---|---|---|---|
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 0.101 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 0.0353 | |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | 0.0115 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 5.365 | |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0173 | |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0173 | |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0173 | |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | 1.21 | |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | 5.365 | |
| Alpha-2A adrenergic receptor | Bos taurus (cattle) | 0.002 | |
| Nischarin | Rattus norvegicus (Norway rat) | 0.3662 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Esbenshade, TA; Han, C; Hollinger, S; Minneman, KP; Theroux, TL | 1 |
| Chiu, AT; McCall, DE; Thoolen, MJ; Timmermans, PB | 1 |
| Dinovo, EC; Haddox, VG; Menon, MK | 1 |
| De Jonge, A; Demarinis, RM; Doods, HN; Hieble, JP; Mathy, MJ; Matthews, WD; Thoolen, MJ; Timmermans, PB; Van Zwieten, PA; Wilffert, B | 1 |
4 other study(ies) available for sk&f 89748 and clonidine
| Article | Year |
|---|---|
Selectivity of agonists for cloned alpha 1-adrenergic receptor subtypes.
Topics: Adrenergic alpha-1 Receptor Agonists; Animals; Binding, Competitive; Catecholamines; Cattle; Cell Line; Cloning, Molecular; Cricetinae; Humans; Imidazoles; Inositol Phosphates; Phenethylamines; Phenoxybenzamine; Radioligand Assay; Rats; Receptors, Adrenergic, alpha-1; Recombinant Proteins; Tetralones | 1994 |
Ca++ utilization in the constriction of rat aorta to full and partial alpha-1 adrenoceptor agonists.
Topics: Adrenergic alpha-Agonists; Animals; Aorta; Calcium; Clonidine; Dose-Response Relationship, Drug; Ethanolamines; Imidazoles; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Potassium; Rats; Rats, Inbred Strains; Tetrahydronaphthalenes | 1986 |
Modification of certain pharmacological effects of ethanol by lipophilic alpha-1 adrenergic agonists.
Topics: Adrenergic alpha-Agonists; Animals; Body Temperature; Clonidine; Drug Interactions; Ethanol; Hypnosis; Imidazoles; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Motor Activity; Pentobarbital; Tetrahydronaphthalenes | 1987 |
Alpha 1-adrenoceptor-mediated vasoconstriction in vivo to enantiomers of SK & F 89748-A.
Topics: Adrenergic alpha-Agonists; Animals; Binding, Competitive; Blood Pressure; Cats; Clonidine; Decerebrate State; Dose-Response Relationship, Drug; Male; Naphthalenes; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Stereoisomerism; Tetrahydronaphthalenes; Vasoconstriction | 1984 |