sk&f 86466 has been researched along with guanabenz in 7 studies
| Studies (sk&f 86466) | Trials (sk&f 86466) | Recent Studies (post-2010) (sk&f 86466) | Studies (guanabenz) | Trials (guanabenz) | Recent Studies (post-2010) (guanabenz) |
|---|---|---|---|---|---|
| 73 | 3 | 9 | 446 | 42 | 96 |
| Protein | Taxonomy | sk&f 86466 (IC50) | guanabenz (IC50) |
|---|---|---|---|
| trace amine-associated receptor 1 | Homo sapiens (human) | 1.173 | |
| Solute carrier family 22 member 1 | Homo sapiens (human) | 4.85 | |
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | 0.204 | |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 0.041 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 0.149 | |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | 1.106 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 2.068 | |
| Amine oxidase [flavin-containing] A | Homo sapiens (human) | 1.787 | |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | 0.472 | |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 0.392 | |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | 0.204 | |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | 2.068 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 0.097 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (85.71) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Downie, JW; Espey, MJ; Gajewski, JB | 1 |
| Cherniack, NS; Cragg, PA; Kou, YR; Prabhakar, NR | 1 |
| Bisgard, GE; Hedrick, MS; Pizarro, J; Ryan, ML | 1 |
| Hieble, JP; Kolpak, DC | 1 |
| Bisgard, GE; Hedrick, MS; Ryan, ML | 1 |
| Coles, SK; Dick, TE; Ernsberger, P | 1 |
| Paul, IA; Peeler, DF; Piletz, JE; Stec, DE; Zhu, H | 1 |
7 other study(ies) available for sk&f 86466 and guanabenz
| Article | Year |
|---|---|
Alpha 2-adrenoceptors not imidazole receptors mediate depression of a sacral spinal reflex in the cat.
Topics: Action Potentials; Adrenergic alpha-Antagonists; Animals; Benzazepines; Cats; Clonidine; Female; Guanabenz; Imidazoline Receptors; Male; Receptors, Adrenergic, alpha; Receptors, Drug; Reflex; Spinal Cord; Yohimbine | 1991 |
Effect of arterial chemoreceptor stimulation: role of norepinephrine in hypoxic chemotransmission.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Benzazepines; Blood Pressure; Carbon Dioxide; Carotid Body; Carotid Sinus; Cats; Chemoreceptor Cells; Guanabenz; Hypoxia; In Vitro Techniques; Infusions, Intra-Arterial; Norepinephrine; Oxygen; Partial Pressure; Receptors, Adrenergic, alpha-2 | 1993 |
Modulation of respiratory rhythm by alpha 2-adrenoceptors in awake and anesthetized goats.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Antagonists; Anesthesia; Animals; Benzazepines; Blood Gas Analysis; Blood Pressure; Carotid Body; Clonidine; Goats; Guanabenz; Heart Rate; Hypercapnia; Phrenic Nerve; Respiration, Artificial; Respiratory Mechanics; Vagotomy | 1994 |
Mediation of the hypotensive action of systemic clonidine in the rat by alpha 2-adrenoceptors.
Topics: Animals; Benzazepines; Blood Pressure; Clonidine; Guanabenz; Imidazoline Receptors; Male; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Drug | 1993 |
Recurrent laryngeal nerve activation by alpha 2 adrenergic agonists in goats.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Apnea; Benzazepines; Carbon Dioxide; Chemoreceptor Cells; Clonidine; Goats; Guanabenz; Partial Pressure; Phrenic Nerve; Recurrent Laryngeal Nerve; Respiration; Sodium Cyanide | 1995 |
Post-hypoxic frequency decline does not depend on alpha2-adrenergic receptors in the adult rat.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Benzazepines; Cerebral Ventricles; Guanabenz; Idazoxan; Infusions, Parenteral; Male; Rats; Rats, Sprague-Dawley; Respiratory Mechanics | 1998 |
Non-adrenergic exploratory behavior induced by moxonidine at mildly hypotensive doses.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Benzazepines; Blood Pressure; Brain; Dose-Response Relationship, Drug; Epinephrine; Exploratory Behavior; Guanabenz; Hypertension; Hypotension; Imidazoles; Imidazoline Receptors; Male; Mice; Receptors, Adrenergic, alpha-2; Receptors, Drug; Sympathetic Nervous System | 2003 |