sk&f 83959 has been researched along with sch 23390 in 5 studies
| Studies (sk&f 83959) | Trials (sk&f 83959) | Recent Studies (post-2010) (sk&f 83959) | Studies (sch 23390) | Trials (sch 23390) | Recent Studies (post-2010) (sch 23390) |
|---|---|---|---|---|---|
| 94 | 0 | 46 | 803 | 0 | 585 |
| Protein | Taxonomy | sk&f 83959 (IC50) | sch 23390 (IC50) |
|---|---|---|---|
| D(2) dopamine receptor | Homo sapiens (human) | 1.0405 | |
| D | Rattus norvegicus (Norway rat) | 0.001 | |
| D(1A) dopamine receptor | Homo sapiens (human) | 0.0461 | |
| D(1B) dopamine receptor | Homo sapiens (human) | 0.0011 | |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | 0.0006 | |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 0.3891 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cai, F; Chen, JG; Fu, H; Gu, J; Liu, C; Liu, J; Ma, LQ; Wang, F; Wang, JH; Xie, N | 1 |
| Ding, F; Gu, X; Li, A; Wang, D; Yin, Y; Zhang, X; Zhen, X; Zhou, J; Zhou, Z | 1 |
| Chu, HY; Hu, GY; Jin, GZ; Yang, Z; Zhao, B; Zhen, X | 1 |
| Cao, X; Chu, HY; Hu, GY; Jin, GZ; Wu, Q; Zhang, A; Zhen, X; Zhou, S | 1 |
| Fan, B; Li, GY; Li, T; Ma, TH; Zheng, YC | 1 |
5 other study(ies) available for sk&f 83959 and sch 23390
| Article | Year |
|---|---|
Activation of phosphatidylinositol-linked novel D1 dopamine receptors inhibits high-voltage-activated Ca2+ currents in primary cultured striatal neurons.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Animals, Newborn; Benzazepines; Biophysics; Calcineurin; Calcium; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Corpus Striatum; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; Female; Glutamate Decarboxylase; Heparin; Male; Membrane Potentials; Models, Biological; Neural Inhibition; Neurons; Patch-Clamp Techniques; Phosphatidylinositols; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Substance P; Type C Phospholipases | 2009 |
Activation of phosphatidylinositol-linked D1-like receptor modulates FGF-2 expression in astrocytes via IP3-dependent Ca2+ signaling.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Animals, Newborn; Astrocytes; Benzazepines; Calcium Signaling; Cells, Cultured; Culture Media, Conditioned; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Enzyme Inhibitors; Fibroblast Growth Factor 2; Gene Expression Regulation; Inositol 1,4,5-Trisphosphate; Mesencephalon; Mice; Mice, Inbred C57BL; Neurons; Neurotoxins; Phosphatidylinositols; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Tyrosine 3-Monooxygenase | 2009 |
Activation of phosphatidylinositol-linked D1-like receptors increases spontaneous glutamate release in rat somatosensory cortical neurons in vitro.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Dopamine Agonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Male; Neurons; Organ Culture Techniques; Phosphatidylinositols; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Somatosensory Cortex; Synaptic Transmission | 2010 |
SKF83959 suppresses excitatory synaptic transmission in rat hippocampus via a dopamine receptor-independent mechanism.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Cells, Cultured; Excitatory Postsynaptic Potentials; Hippocampus; Male; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Synaptic Transmission | 2011 |
The D₁ dopamine receptor agonist, SKF83959, attenuates hydrogen peroxide-induced injury in RGC-5 cells involving the extracellular signal-regulated kinase/p38 pathways.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Butadienes; Cell Line; Dopamine Agonists; Dopamine Antagonists; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation; Hydrogen Peroxide; Imidazoles; JNK Mitogen-Activated Protein Kinases; Mice; Nitriles; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Pyridines; Rats; Receptors, Dopamine D1; Retinal Ganglion Cells; Signal Transduction | 2012 |