Compounds > sk&f 82958

sk&f 82958 and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

sk&f 82958 has been researched along with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's9 (69.23)18.2507
2000's4 (30.77)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Boyce, S; Iversen, SD; Rupniak, NM; Steventon, M1
Fukuda, T; Nomoto, M1
Bédard, PJ; Blanchet, PJ; Grondin, R1
Bédard, PJ; Blanchet, PJ; Di Paolo, T; Goulet, M; Grondin, R1
Domino, EF1
Kuno, S1
Bédard, PJ; Di Paolo, T; Goulet, M; Grondin, R; Morissette, M2
Bédard, PJ; Blanchet, PJ; Calon, F; Di Paolo, T; Goulet, M; Grondin, R; Morissette, M2
Bédard, PJ; Blanchet, PJ; Calon, F; Di Paolo, T; Ghribi, O; Goulet, M; Grondin, R; Morissette, M1
Bédard, PJ; Grégoire, L; Samadi, P1
Domino, EF; Ni, L1

Other Studies

13 other study(ies) available for sk&f 82958 and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

ArticleYear
Weak antiparkinsonian activity of the D1 agonist C-APB (SKF 82958) and lack of synergism with a D2 agonist in primates.
    Clinical neuropharmacology, 1992, Volume: 15, Issue:4

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antiparkinson Agents; Benzazepines; Dopamine Agents; Drug Synergism; Male; Motor Activity; Parkinson Disease, Secondary; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Saimiri

1992
The effects of D1 and D2 dopamine receptor agonist and antagonist on parkinsonism in chronic MPTP-treated monkeys.
    Advances in neurology, 1993, Volume: 60

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antiparkinson Agents; Benzazepines; Callithrix; Corpus Striatum; Dopamine; Dopamine Agents; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Female; Indoles; Male; Motor Activity; Parkinson Disease, Secondary; Phenanthridines; Receptors, Dopamine D1; Receptors, Dopamine D2

1993
Dyskinesia and wearing-off following dopamine D1 agonist treatment in drug-naive 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned primates.
    Movement disorders : official journal of the Movement Disorder Society, 1996, Volume: 11, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Benzazepines; Brain; Dopamine Agents; Dopamine Agonists; Dyskinesia, Drug-Induced; Female; Levodopa; Macaca fascicularis; Motor Skills; Neurologic Examination; Parkinson Disease, Secondary; Receptors, Dopamine D1

1996
Dyskinesias and tolerance induced by chronic treatment with a D1 agonist administered in pulsatile or continuous mode do not correlate with changes of putaminal D1 receptors in drug-naive MPTP monkeys.
    Brain research, 1996, May-06, Volume: 719, Issue:1-2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Benzazepines; Catecholamines; Dopamine Agonists; Drug Administration Schedule; Drug Tolerance; Dyskinesia, Drug-Induced; Female; Infusion Pumps, Implantable; Injections, Subcutaneous; Macaca fascicularis; Motor Activity; Parkinson Disease, Secondary; Putamen; Receptors, Dopamine D1

1996
Selective full dopamine D1-like (SKF-82958) and D2-like (N-0923) agonist combination in the MPTP monkey model of hemiparkinsonism.
    Brain research bulletin, 1997, Volume: 43, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Benzazepines; Disease Models, Animal; Dopamine Agonists; Drug Evaluation, Preclinical; Drug Interactions; Female; Macaca nemestrina; Parkinson Disease, Secondary; Receptors, Dopamine D1; Receptors, Dopamine D2; Tetrahydronaphthalenes; Thiophenes

1997
Differential therapeutic effects of dopamine D1 and D2 agonists in MPTP-induced parkinsonian monkeys: clinical implications.
    European neurology, 1997, Volume: 38 Suppl 1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antiparkinson Agents; Apomorphine; Benzazepines; Dopamine Agonists; Macaca fascicularis; Parkinson Disease, Secondary; Receptors, Dopamine D1; Receptors, Dopamine D2

1997
Differential regulation of striatal preproenkephalin and preprotachykinin mRNA levels in MPTP-lesioned monkeys chronically treated with dopamine D1 or D2 receptor agonists.
    Journal of neurochemistry, 1999, Volume: 72, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Behavior, Animal; Benzazepines; Brain Chemistry; Cabergoline; Corpus Striatum; Denervation; Dopamine Agents; Dopamine Agonists; Enkephalins; Ergolines; Female; Gene Expression; Macaca fascicularis; Movement Disorders; Protein Precursors; Pulsatile Flow; Receptors, Dopamine D1; Receptors, Dopamine D2; RNA, Messenger; Tachykinins

1999
Chronic D1 and D2 dopaminomimetic treatment of MPTP-denervated monkeys: effects on basal ganglia GABA(A)/benzodiazepine receptor complex and GABA content.
    Neurochemistry international, 1999, Volume: 35, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Autoradiography; Basal Ganglia; Benzazepines; Cabergoline; Denervation; Dopamine Agonists; Ergolines; Female; Flunitrazepam; gamma-Aminobutyric Acid; Macaca fascicularis; Ovariectomy; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, GABA-A; Tritium

1999
Dopamine D1 receptor mRNA and receptor levels in the striatum of MPTP monkeys chronically treated with SKF-82958.
    European journal of pharmacology, 1999, Aug-13, Volume: 378, Issue:3

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Benzazepines; Caudate Nucleus; Corpus Striatum; Dopamine; Dopamine Agents; Dopamine Agonists; Macaca fascicularis; Nucleus Accumbens; Putamen; Receptors, Dopamine D1; RNA, Messenger

1999
125I-CGP 64213 binding to GABA(B) receptors in the brain of monkeys: effect of MPTP and dopaminomimetic treatments.
    Experimental neurology, 2000, Volume: 163, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antiparkinson Agents; Autoradiography; Basal Ganglia; Benzazepines; Benzoates; Binding Sites; Brain; Cabergoline; Corpus Striatum; Dopamine Agonists; Drug Administration Schedule; Dyskinesia, Drug-Induced; Ergolines; Female; GABA Antagonists; GABA-B Receptor Antagonists; Injections, Subcutaneous; Iodine Radioisotopes; Macaca fascicularis; Organophosphorus Compounds; Parkinson Disease, Secondary; Receptors, GABA-B; Substantia Nigra; Thalamus

2000
Alteration of glutamate receptors in the striatum of dyskinetic 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated monkeys following dopamine agonist treatment.
    Progress in neuro-psychopharmacology & biological psychiatry, 2002, Volume: 26, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Benzazepines; Corpus Striatum; Dopamine Agonists; Female; Glutamic Acid; Glutamine; Glycine; Macaca fascicularis; Ovariectomy; Parkinsonian Disorders; Receptors, Glutamate; Reference Values

2002
Opioid antagonists increase the dyskinetic response to dopaminergic agents in parkinsonian monkeys: interaction between dopamine and opioid systems.
    Neuropharmacology, 2003, Volume: 45, Issue:7

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Benzazepines; Dopamine; Dopamine Agents; Dopamine Agonists; Dyskinesia, Drug-Induced; Endorphins; Female; Levodopa; Macaca fascicularis; Motor Activity; Naloxone; Naltrexone; Narcotic Antagonists; Parkinson Disease, Secondary; Quinpirole; Receptors, Dopamine D1; Receptors, Dopamine D2; Synaptic Transmission

2003
Biperiden enhances L-DOPA methyl ester and dopamine D(l) receptor agonist SKF-82958 but antagonizes D(2)/D(3) receptor agonist rotigotine antihemiparkinsonian actions.
    European journal of pharmacology, 2008, Dec-03, Volume: 599, Issue:1-3

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antiparkinson Agents; Behavior, Animal; Benzazepines; Biperiden; Disease Models, Animal; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Interactions; Female; Levodopa; Macaca nemestrina; Muscarinic Antagonists; Parkinsonian Disorders; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Dopamine D3; Tetrahydronaphthalenes; Thiophenes

2008